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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GFI1B

Z-value: 0.77

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Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
GFI1B
ENSG00000165702.8 growth factor independent 1B transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1Bhg19_v2_chr9_+_135854091_135854159-0.144.9e-01Click!

Activity profile of GFI1B motif

Sorted Z-values of GFI1B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41362796 3.36 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr4_-_159080806 2.72 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr4_+_42399856 2.43 ENST00000319234.4
SHISA3
shisa family member 3
chr4_-_186697044 2.37 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr15_-_70994612 1.53 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_164528866 1.49 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr9_-_14180778 1.48 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr4_-_186696425 1.40 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr8_-_6420565 1.26 ENST00000338312.6
ANGPT2
angiopoietin 2
chr1_+_33005020 1.15 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr3_-_18466026 1.14 ENST00000417717.2
SATB1
SATB homeobox 1
chr2_-_136873735 1.13 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr16_+_4838412 1.12 ENST00000589327.1
SMIM22
small integral membrane protein 22
chr8_-_6420759 1.11 ENST00000523120.1
ANGPT2
angiopoietin 2
chr7_+_79765071 1.09 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr19_+_36602104 1.07 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr7_-_86595190 1.06 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr16_+_12058961 1.03 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr16_+_12059050 1.02 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_210406121 0.99 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr10_+_94590910 0.99 ENST00000371547.4
EXOC6
exocyst complex component 6
chr12_-_59314246 0.97 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr3_+_152017924 0.96 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr14_-_23285069 0.95 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_+_132455118 0.92 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr8_-_6420777 0.90 ENST00000415216.1
ANGPT2
angiopoietin 2
chr14_+_77228532 0.90 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr8_-_6420930 0.89 ENST00000325203.5
ANGPT2
angiopoietin 2
chr14_-_23285011 0.88 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_102268484 0.87 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_+_44229846 0.82 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr1_+_203651937 0.82 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr22_-_37880543 0.82 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_129473859 0.80 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr8_-_102275131 0.78 ENST00000523121.1
KB-1410C5.2
KB-1410C5.2
chr6_+_132455526 0.75 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chrX_+_84499081 0.72 ENST00000276123.3
ZNF711
zinc finger protein 711
chr5_+_150591678 0.70 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr5_-_64920115 0.65 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr12_+_48513009 0.64 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM
phosphofructokinase, muscle
chr10_+_63661053 0.63 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_-_5321549 0.62 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr4_+_48807155 0.62 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr1_-_68698197 0.62 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr4_+_26585538 0.61 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr10_+_97471508 0.60 ENST00000453258.2
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr17_-_46688334 0.59 ENST00000239165.7
HOXB7
homeobox B7
chr12_+_48513570 0.58 ENST00000551804.1
PFKM
phosphofructokinase, muscle
chr10_+_52152766 0.58 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr1_-_182360918 0.58 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chrX_+_129473916 0.58 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chrX_+_84498989 0.57 ENST00000395402.1
ZNF711
zinc finger protein 711
chr17_+_61554413 0.56 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
ACE
angiotensin I converting enzyme
chr2_-_85788652 0.56 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr12_+_124155652 0.56 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chrX_+_84499038 0.54 ENST00000373165.3
ZNF711
zinc finger protein 711
chr19_+_35417939 0.54 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr6_+_42018614 0.53 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr11_+_76571911 0.53 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
ACER3
alkaline ceramidase 3
chr19_+_55417499 0.53 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr19_+_35417844 0.52 ENST00000601957.1
ZNF30
zinc finger protein 30
chr19_-_45681482 0.52 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr3_-_165555200 0.51 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr19_+_35417798 0.51 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
ZNF30
zinc finger protein 30
chr2_-_86116093 0.51 ENST00000377332.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_-_110371664 0.50 ENST00000545389.1
ENST00000423520.1
SEPT10
septin 10
chr1_-_182361327 0.50 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr2_+_47630108 0.49 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr17_-_79827808 0.49 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr22_+_32455111 0.48 ENST00000543737.1
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr22_+_19951192 0.48 ENST00000428707.1
COMT
catechol-O-methyltransferase
chr17_-_295730 0.47 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr11_-_71791726 0.47 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr1_-_182360498 0.46 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chrX_+_7137475 0.46 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr17_-_79481666 0.46 ENST00000575659.1
ACTG1
actin, gamma 1
chr4_+_39184024 0.44 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr7_+_120591170 0.44 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr2_+_234104079 0.44 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr18_+_77905794 0.42 ENST00000587254.1
ENST00000586421.1
AC139100.2
Uncharacterized protein
chr6_-_131384347 0.41 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_+_27799389 0.41 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr8_+_11291429 0.41 ENST00000533578.1
C8orf12
chromosome 8 open reading frame 12
chr6_-_131384373 0.41 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_-_110371412 0.41 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
SEPT10
septin 10
chr1_-_21377383 0.41 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_110656005 0.41 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr12_+_72332618 0.40 ENST00000333850.3
TPH2
tryptophan hydroxylase 2
chr6_+_90272027 0.40 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr1_+_15668240 0.40 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_23886285 0.40 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr16_+_69221028 0.40 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr6_+_44215603 0.40 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr14_+_22538811 0.39 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr10_-_120355149 0.38 ENST00000239032.2
PRLHR
prolactin releasing hormone receptor
chr11_-_33774944 0.37 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr14_-_64194745 0.37 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr7_-_99332719 0.36 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr17_+_74075263 0.36 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr13_+_76362974 0.36 ENST00000497947.2
LMO7
LIM domain 7
chr7_+_134551583 0.36 ENST00000435928.1
CALD1
caldesmon 1
chr19_+_55417530 0.36 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr1_+_220701740 0.36 ENST00000366917.4
MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_-_10978103 0.36 ENST00000404824.2
PDIA6
protein disulfide isomerase family A, member 6
chr18_-_48723690 0.36 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr19_+_41103063 0.36 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr6_-_131384412 0.35 ENST00000445890.2
ENST00000368128.2
ENST00000337057.3
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_201140673 0.35 ENST00000367333.2
TMEM9
transmembrane protein 9
chr2_-_85788605 0.35 ENST00000233838.4
GGCX
gamma-glutamyl carboxylase
chr11_-_82745238 0.35 ENST00000531021.1
RAB30
RAB30, member RAS oncogene family
chr5_+_79703823 0.35 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
ZFYVE16
zinc finger, FYVE domain containing 16
chr6_-_7911042 0.35 ENST00000379757.4
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_+_57878859 0.34 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr2_-_158732340 0.34 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr1_-_21377447 0.34 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_+_109102652 0.34 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr6_-_131321863 0.34 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_68698222 0.33 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr1_-_179834311 0.33 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr17_-_3496171 0.33 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr13_+_111806055 0.33 ENST00000218789.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr11_+_119056178 0.32 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr19_+_17337473 0.31 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr19_-_43269809 0.31 ENST00000406636.3
ENST00000404209.4
ENST00000306511.4
PSG8
pregnancy specific beta-1-glycoprotein 8
chr3_+_152017360 0.31 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr1_+_95616933 0.31 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr7_-_100808843 0.30 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr4_+_154125565 0.30 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr2_+_176987088 0.30 ENST00000249499.6
HOXD9
homeobox D9
chr16_+_4838393 0.30 ENST00000589721.1
SMIM22
small integral membrane protein 22
chr16_+_12995614 0.30 ENST00000423335.2
SHISA9
shisa family member 9
chr22_-_24241117 0.30 ENST00000406213.1
AP000350.4
Uncharacterized protein
chr14_-_68162464 0.30 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr19_+_10736183 0.30 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
SLC44A2
solute carrier family 44 (choline transporter), member 2
chr7_-_100808394 0.29 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr1_-_94703118 0.29 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr2_-_110371720 0.29 ENST00000356688.4
SEPT10
septin 10
chr7_+_102036798 0.29 ENST00000397912.3
ENST00000354783.4
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr11_+_30253410 0.29 ENST00000533718.1
FSHB
follicle stimulating hormone, beta polypeptide
chr1_+_10290822 0.28 ENST00000377083.1
KIF1B
kinesin family member 1B
chr7_+_44040488 0.28 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr2_-_110371777 0.28 ENST00000397712.2
SEPT10
septin 10
chr15_-_59041768 0.28 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM10
ADAM metallopeptidase domain 10
chr19_+_17862274 0.27 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chr8_-_12668962 0.27 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr15_+_32933866 0.27 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
SCG5
secretogranin V (7B2 protein)
chr6_+_153019023 0.27 ENST00000367245.5
ENST00000529453.1
MYCT1
myc target 1
chr12_-_123752624 0.27 ENST00000542174.1
ENST00000535796.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr12_+_100967420 0.27 ENST00000266754.5
ENST00000547754.1
GAS2L3
growth arrest-specific 2 like 3
chr11_-_7961141 0.26 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr14_+_58765103 0.26 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr6_-_56708459 0.26 ENST00000370788.2
DST
dystonin
chr1_+_39796810 0.25 ENST00000289893.4
MACF1
microtubule-actin crosslinking factor 1
chr12_-_4553385 0.25 ENST00000543077.1
FGF6
fibroblast growth factor 6
chr20_-_4795747 0.25 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_+_74663896 0.25 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr10_-_23633720 0.24 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr1_-_220219775 0.24 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr14_-_53417732 0.24 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr3_+_132036243 0.24 ENST00000475741.1
ENST00000351273.7
ACPP
acid phosphatase, prostate
chr11_+_70116779 0.24 ENST00000253925.7
ENST00000389547.3
PPFIA1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr1_+_162602244 0.23 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr4_-_140216948 0.23 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_+_64085560 0.23 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr11_-_5462744 0.23 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr14_-_93214915 0.23 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
LGMN
legumain
chr1_+_220701456 0.23 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr7_+_123488124 0.22 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr11_+_55944094 0.22 ENST00000312298.1
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr11_-_61582579 0.22 ENST00000539419.1
ENST00000545245.1
ENST00000545405.1
ENST00000542506.1
FADS1
fatty acid desaturase 1
chr9_-_110540419 0.22 ENST00000398726.3
AL162389.1
Uncharacterized protein
chr11_-_94964354 0.22 ENST00000536441.1
SESN3
sestrin 3
chr11_+_101785727 0.22 ENST00000263468.8
KIAA1377
KIAA1377
chr8_+_62200509 0.22 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr12_+_48876275 0.22 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr7_+_129007964 0.21 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_+_164529004 0.21 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr3_-_49466686 0.21 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr21_+_35014783 0.21 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
ITSN1
intersectin 1 (SH3 domain protein)
chr4_+_15471489 0.21 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A
coiled-coil and C2 domain containing 2A
chr14_-_80677815 0.21 ENST00000557125.1
ENST00000555750.1
DIO2
deiodinase, iodothyronine, type II
chr21_+_30968360 0.21 ENST00000333765.4
GRIK1-AS2
GRIK1 antisense RNA 2
chr6_-_56707943 0.21 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr8_-_22926623 0.21 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr3_-_187454281 0.21 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr17_+_3100813 0.21 ENST00000381951.1
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr14_-_75330537 0.20 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr1_+_45792541 0.20 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr3_+_121311966 0.20 ENST00000338040.4
FBXO40
F-box protein 40
chr4_-_104640973 0.20 ENST00000304883.2
TACR3
tachykinin receptor 3
chr16_+_30996502 0.20 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_+_131100515 0.20 ENST00000537561.1
ENST00000359850.3
ENST00000521288.1
ENST00000502852.1
NUDT16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chr5_+_53813536 0.20 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chr12_-_56756553 0.19 ENST00000398189.3
ENST00000541105.1
APOF
apolipoprotein F
chr6_+_46620676 0.19 ENST00000371347.5
ENST00000411689.2
SLC25A27
solute carrier family 25, member 27
chr6_-_161695074 0.19 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr19_+_57862622 0.19 ENST00000391705.3
ENST00000443917.2
ENST00000598744.1
ZNF304
zinc finger protein 304
chr16_+_31366455 0.19 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr15_-_83378638 0.19 ENST00000261722.3
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr5_+_56111361 0.19 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.4 2.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.4 1.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.4 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 0.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 0.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 1.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 1.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 3.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.5 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 1.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.3 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 3.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.4 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.5 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.5 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.1 GO:0006788 heme oxidation(GO:0006788)
0.1 0.3 GO:1904647 response to rotenone(GO:1904647)
0.1 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.9 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.2 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 1.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:2000566 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 2.0 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.6 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.9 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.5 GO:0006706 steroid catabolic process(GO:0006706)
0.0 1.3 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 1.5 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.2 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.2 0.5 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.7 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.3 GO:0097386 glial cell projection(GO:0097386)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 3.7 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 1.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 0.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.5 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.2 1.5 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 4.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.8 GO:0032451 demethylase activity(GO:0032451)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 4.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 4.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism