Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for GGCAAGA
Z-value: 0.25
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miRNA associated with seed GGCAAGA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-31-5p
|
MIMAT0000089 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_-_72441315 Show fit | 0.54 |
ENST00000305425.4
ENST00000313174.7 ENST00000354591.4 |
dachshund homolog 1 (Drosophila) |
|
| chr10_-_131762105 Show fit | 0.41 |
ENST00000368648.3
ENST00000355311.5 |
early B-cell factor 3 |
|
| chr2_+_45878790 Show fit | 0.37 |
ENST00000306156.3
|
protein kinase C, epsilon |
|
| chr2_+_7057523 Show fit | 0.34 |
ENST00000320892.6
|
ring finger protein 144A |
|
| chr4_+_87856129 Show fit | 0.23 |
ENST00000395146.4
ENST00000507468.1 |
AF4/FMR2 family, member 1 |
|
| chr15_-_71055878 Show fit | 0.23 |
ENST00000322954.6
|
uveal autoantigen with coiled-coil domains and ankyrin repeats |
|
| chr6_-_99395787 Show fit | 0.22 |
ENST00000369244.2
ENST00000229971.1 |
F-box and leucine-rich repeat protein 4 |
|
| chr8_-_89339705 Show fit | 0.22 |
ENST00000286614.6
|
matrix metallopeptidase 16 (membrane-inserted) |
|
| chr9_-_134145880 Show fit | 0.20 |
ENST00000372269.3
ENST00000464831.1 |
family with sequence similarity 78, member A |
|
| chr10_-_52383644 Show fit | 0.20 |
ENST00000361781.2
|
sphingomyelin synthase 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGCAAGA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.1 | 0.4 | GO:0035668 | TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669) |
| 0.0 | 0.2 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.1 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.0 | 0.1 | GO:0045976 | negative regulation of mitotic cell cycle, embryonic(GO:0045976) |
| 0.0 | 0.1 | GO:0021793 | chemorepulsion of branchiomotor axon(GO:0021793) |
| 0.0 | 0.1 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.0 | 0.1 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
| 0.0 | 0.1 | GO:1901143 | insulin catabolic process(GO:1901143) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.1 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.1 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 0.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.0 | 0.2 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 0.2 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.0 | 0.1 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.0 | 0.1 | GO:0043559 | insulin binding(GO:0043559) |
| 0.0 | 0.1 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID LPA4 PATHWAY | LPA4-mediated signaling events |