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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GLI2

Z-value: 0.69

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Transcription factors associated with GLI2

Gene Symbol Gene ID Gene Info
ENSG00000074047.16 GLI family zinc finger 2

Activity profile of GLI2 motif

Sorted Z-values of GLI2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_205782304 1.47 ENST00000367137.3
solute carrier family 41 (magnesium transporter), member 1
chr12_+_113354341 1.06 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_+_41158742 0.95 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr1_-_47407097 0.77 ENST00000457840.2
cytochrome P450, family 4, subfamily A, polypeptide 11
chr5_+_131409476 0.74 ENST00000296871.2
colony stimulating factor 2 (granulocyte-macrophage)
chr7_-_47579188 0.67 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
tensin 3
chr19_+_44084696 0.66 ENST00000562255.1
ENST00000569031.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr19_-_7939319 0.66 ENST00000539422.1
Protein FLJ22184
chr15_-_78526855 0.63 ENST00000541759.1
ENST00000558130.1
acyl-CoA synthetase bubblegum family member 1
chr11_+_13690249 0.57 ENST00000532701.1
fatty acyl CoA reductase 1
chr8_+_31497271 0.56 ENST00000520407.1
neuregulin 1
chr17_+_39388700 0.51 ENST00000411528.2
keratin associated protein 9-3
chr11_-_19262486 0.49 ENST00000250024.4
E2F transcription factor 8
chr3_-_107809816 0.48 ENST00000361309.5
ENST00000355354.7
CD47 molecule
chr15_+_59063478 0.47 ENST00000559228.1
ENST00000450403.2
family with sequence similarity 63, member B
chr17_+_77030267 0.45 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr20_+_23168759 0.44 ENST00000411595.1
RP4-737E23.2
chr16_+_88872176 0.42 ENST00000569140.1
chromatin licensing and DNA replication factor 1
chr17_-_3819751 0.42 ENST00000225538.3
purinergic receptor P2X, ligand-gated ion channel, 1
chr14_-_52535712 0.41 ENST00000216286.5
ENST00000541773.1
nidogen 2 (osteonidogen)
chr12_+_4671352 0.40 ENST00000542744.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr9_+_126118449 0.40 ENST00000359999.3
ENST00000373631.3
crumbs homolog 2 (Drosophila)
chr20_-_55100981 0.39 ENST00000243913.4
glucosaminyl (N-acetyl) transferase family member 7
chr14_+_94393605 0.38 ENST00000556222.1
ENST00000554404.1
ENST00000557000.2
family with sequence similarity 181, member A
chr19_+_44085189 0.38 ENST00000562365.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr9_+_126131131 0.37 ENST00000373629.2
crumbs homolog 2 (Drosophila)
chr10_-_49701686 0.36 ENST00000417247.2
Rho GTPase activating protein 22
chr16_+_2880296 0.35 ENST00000571723.1
zymogen granule protein 16B
chr1_-_45308616 0.35 ENST00000447098.2
ENST00000372192.3
patched 2
chr5_-_150460914 0.35 ENST00000389378.2
TNFAIP3 interacting protein 1
chr5_-_172036436 0.35 ENST00000601856.1
AC027309.1
chr5_-_95297534 0.35 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr1_-_21948906 0.35 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr16_+_2880254 0.35 ENST00000570670.1
zymogen granule protein 16B
chr14_+_71108460 0.34 ENST00000256367.2
tetratricopeptide repeat domain 9
chr5_-_58571935 0.34 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr16_-_11681023 0.34 ENST00000570904.1
ENST00000574701.1
lipopolysaccharide-induced TNF factor
chr15_+_67430339 0.33 ENST00000439724.3
SMAD family member 3
chr2_-_100759037 0.33 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
AF4/FMR2 family, member 3
chr7_-_23053693 0.32 ENST00000409763.1
ENST00000409923.1
family with sequence similarity 126, member A
chr7_-_151511911 0.32 ENST00000392801.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_10464570 0.32 ENST00000529739.1
tyrosine kinase 2
chr14_+_94577074 0.31 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr16_-_30022293 0.31 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
double C2-like domains, alpha
chr2_+_11295624 0.30 ENST00000402361.1
ENST00000428481.1
PQ loop repeat containing 3
chr19_-_49015050 0.30 ENST00000600059.1
lemur tyrosine kinase 3
chr5_-_9546180 0.29 ENST00000382496.5
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr14_+_96342729 0.29 ENST00000504119.1
long intergenic non-protein coding RNA 617
chr2_+_241564655 0.29 ENST00000407714.1
G protein-coupled receptor 35
chr7_-_23053719 0.29 ENST00000432176.2
ENST00000440481.1
family with sequence similarity 126, member A
chr12_-_110883346 0.29 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr17_+_29248953 0.29 ENST00000581285.1
ArfGAP with dual PH domains 2
chr3_+_32993065 0.29 ENST00000330953.5
chemokine (C-C motif) receptor 4
chr3_+_88108381 0.28 ENST00000473136.1
Uncharacterized protein
chr14_-_24615523 0.28 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr6_+_163148973 0.28 ENST00000366888.2
PARK2 co-regulated
chr12_-_132690337 0.28 ENST00000541995.1
ENST00000542942.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr12_+_77158021 0.28 ENST00000550876.1
zinc finger, DHHC-type containing 17
chr19_+_45445524 0.28 ENST00000591600.1
apolipoprotein C-IV
chr16_-_74700737 0.28 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
ring finger and WD repeat domain 3
chr19_-_40791211 0.28 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr14_-_24615805 0.28 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_+_2521500 0.27 ENST00000293973.1
netrin 3
chr3_+_42727011 0.27 ENST00000287777.4
kelch-like family member 40
chr16_+_89686991 0.27 ENST00000393092.3
dipeptidase 1 (renal)
chr19_-_11039188 0.27 ENST00000588347.1
Yip1 domain family, member 2
chr8_+_1922024 0.26 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr1_-_153013588 0.26 ENST00000360379.3
small proline-rich protein 2D
chr1_-_21978312 0.26 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr19_+_48824711 0.26 ENST00000599704.1
epithelial membrane protein 3
chr12_+_7079944 0.26 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr20_-_30310656 0.26 ENST00000376055.4
BCL2-like 1
chr16_+_57653989 0.26 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr14_-_71107921 0.26 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr6_-_163148700 0.25 ENST00000366894.1
ENST00000338468.3
parkin RBR E3 ubiquitin protein ligase
chr16_+_57653854 0.25 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr20_+_48599506 0.25 ENST00000244050.2
snail family zinc finger 1
chr16_+_67062996 0.25 ENST00000561924.2
core-binding factor, beta subunit
chr8_+_42010464 0.24 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
adaptor-related protein complex 3, mu 2 subunit
chr20_-_30310693 0.24 ENST00000307677.4
ENST00000420653.1
BCL2-like 1
chr18_+_56807096 0.24 ENST00000588875.1
SEC11 homolog C (S. cerevisiae)
chr19_+_48828582 0.24 ENST00000270221.6
ENST00000596315.1
epithelial membrane protein 3
chr2_+_186603545 0.24 ENST00000424728.1
fibrous sheath interacting protein 2
chrX_+_152086373 0.24 ENST00000318529.8
zinc finger protein 185 (LIM domain)
chr1_+_165796753 0.24 ENST00000367879.4
uridine-cytidine kinase 2
chr20_+_44746939 0.24 ENST00000372276.3
CD40 molecule, TNF receptor superfamily member 5
chr11_+_18416133 0.24 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr17_+_56270084 0.23 ENST00000225371.5
eosinophil peroxidase
chr2_+_37571845 0.23 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr11_+_18416103 0.23 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr3_-_179169330 0.23 ENST00000232564.3
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr12_-_89920030 0.23 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr21_-_45079341 0.23 ENST00000443485.1
ENST00000291560.2
heat shock transcription factor 2 binding protein
chr2_+_37571717 0.22 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chrX_-_15332665 0.22 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chrX_-_48271344 0.22 ENST00000376884.2
ENST00000396928.1
synovial sarcoma, X breakpoint 4B
chr6_+_43739697 0.22 ENST00000230480.6
vascular endothelial growth factor A
chr1_-_241520385 0.22 ENST00000366564.1
regulator of G-protein signaling 7
chr3_+_179280668 0.22 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
actin-like 6A
chr7_-_27170352 0.22 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr16_+_56385290 0.22 ENST00000564727.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_-_241520525 0.22 ENST00000366565.1
regulator of G-protein signaling 7
chrX_-_52683950 0.22 ENST00000298181.5
synovial sarcoma, X breakpoint 7
chr10_+_71389983 0.22 ENST00000373279.4
chromosome 10 open reading frame 35
chr19_+_10563567 0.22 ENST00000344979.3
phosphodiesterase 4A, cAMP-specific
chr16_+_2880369 0.22 ENST00000572863.1
zymogen granule protein 16B
chr19_+_45417921 0.22 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr1_+_70876891 0.21 ENST00000411986.2
cystathionase (cystathionine gamma-lyase)
chr3_-_192635943 0.21 ENST00000392452.2
Mab-21 domain containing 2
chr12_+_112563335 0.21 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr8_+_134203303 0.21 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WNT1 inducible signaling pathway protein 1
chr4_+_95128996 0.21 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_-_994302 0.21 ENST00000265846.5
ArfGAP with dual PH domains 1
chr14_-_106068065 0.21 ENST00000390541.2
immunoglobulin heavy constant epsilon
chr8_+_11627148 0.21 ENST00000436750.3
nei endonuclease VIII-like 2 (E. coli)
chr22_+_39378375 0.21 ENST00000402182.3
ENST00000333467.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr22_+_39378346 0.20 ENST00000407298.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr3_-_45957088 0.20 ENST00000539217.1
leucine zipper transcription factor-like 1
chr4_+_95129061 0.20 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr18_+_12948000 0.20 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr11_-_18765389 0.20 ENST00000477854.1
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr1_+_35220613 0.20 ENST00000338513.1
gap junction protein, beta 5, 31.1kDa
chr15_+_98503922 0.20 ENST00000268042.6
arrestin domain containing 4
chr8_+_11627205 0.20 ENST00000455213.2
ENST00000403422.3
ENST00000528323.1
ENST00000284503.6
nei endonuclease VIII-like 2 (E. coli)
chr16_+_28996114 0.20 ENST00000395461.3
linker for activation of T cells
chr16_+_2880157 0.20 ENST00000382280.3
zymogen granule protein 16B
chr3_+_153839149 0.19 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr11_+_62495541 0.19 ENST00000530625.1
ENST00000513247.2
tetratricopeptide repeat domain 9C
chr10_+_115438920 0.19 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr20_+_44746885 0.19 ENST00000372285.3
CD40 molecule, TNF receptor superfamily member 5
chr6_-_168479839 0.19 ENST00000283309.6
FERM domain containing 1
chr7_+_5919458 0.19 ENST00000416608.1
oncomodulin
chr5_+_113769205 0.19 ENST00000503706.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr3_-_50336548 0.19 ENST00000450489.1
ENST00000513170.1
ENST00000450982.1
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr2_-_43266680 0.19 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr9_-_130742792 0.19 ENST00000373095.1
family with sequence similarity 102, member A
chr19_-_54567159 0.19 ENST00000338372.2
ENST00000376626.1
V-set and transmembrane domain containing 1
chr12_-_93323013 0.19 ENST00000322349.8
early endosome antigen 1
chr5_+_98109322 0.19 ENST00000513185.1
repulsive guidance molecule family member b
chr2_+_65215604 0.18 ENST00000531327.1
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_-_243418621 0.18 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr13_-_30169807 0.18 ENST00000380752.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_70876926 0.18 ENST00000370938.3
ENST00000346806.2
cystathionase (cystathionine gamma-lyase)
chr4_+_38511367 0.18 ENST00000507056.1
RP11-213G21.1
chr17_+_73629500 0.18 ENST00000375215.3
small integral membrane protein 5
chr12_+_101673872 0.18 ENST00000261637.4
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr17_-_77925806 0.18 ENST00000574241.2
TBC1 domain family, member 16
chr9_+_4839762 0.18 ENST00000448872.2
ENST00000441844.1
RNA terminal phosphate cyclase-like 1
chr14_-_51297197 0.18 ENST00000382043.4
ninein (GSK3B interacting protein)
chr1_+_154966058 0.18 ENST00000392487.1
lens epithelial protein
chr5_-_95297678 0.18 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr1_-_52499443 0.18 ENST00000371614.1
KTI12 homolog, chromatin associated (S. cerevisiae)
chr5_-_89705537 0.18 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
centrin, EF-hand protein, 3
chr9_+_841690 0.18 ENST00000382276.3
doublesex and mab-3 related transcription factor 1
chr19_+_55795493 0.18 ENST00000309383.1
BR serine/threonine kinase 1
chr10_+_70320413 0.18 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr5_-_60458179 0.17 ENST00000507416.1
ENST00000339020.3
small integral membrane protein 15
chr2_+_128180842 0.17 ENST00000402125.2
protein C (inactivator of coagulation factors Va and VIIIa)
chr14_+_24605389 0.17 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_+_10381769 0.17 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr5_+_161494770 0.17 ENST00000414552.2
ENST00000361925.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr3_-_184870751 0.17 ENST00000335012.2
chromosome 3 open reading frame 70
chr16_-_11681316 0.17 ENST00000571688.1
lipopolysaccharide-induced TNF factor
chr7_-_131241361 0.17 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr22_-_50964849 0.17 ENST00000543927.1
ENST00000423348.1
SCO2 cytochrome c oxidase assembly protein
chr21_-_28338732 0.17 ENST00000284987.5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr15_+_49447947 0.17 ENST00000327171.3
ENST00000560654.1
galactokinase 2
chr12_-_89919765 0.17 ENST00000541909.1
ENST00000313546.3
POC1 centriolar protein B
chr12_+_57853918 0.17 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr20_-_61051026 0.17 ENST00000252997.2
GATA binding protein 5
chr16_+_67063262 0.17 ENST00000565389.1
core-binding factor, beta subunit
chr19_+_3539152 0.16 ENST00000329493.5
chromosome 19 open reading frame 71
chr4_-_57687847 0.16 ENST00000504762.1
ENST00000248701.4
ENST00000506738.1
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
chr10_-_99258135 0.16 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr10_+_75936444 0.16 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chr17_+_7483761 0.16 ENST00000584180.1
CD68 molecule
chr3_-_126236605 0.16 ENST00000290868.2
urocanate hydratase 1
chr1_-_38273840 0.16 ENST00000373044.2
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr5_+_89770664 0.16 ENST00000503973.1
ENST00000399107.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr12_+_112563303 0.16 ENST00000412615.2
TRAF-type zinc finger domain containing 1
chr11_+_65819802 0.16 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
splicing factor 3b, subunit 2, 145kDa
chr16_+_67063036 0.16 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr17_-_46799872 0.16 ENST00000290294.3
prostate cancer susceptibility candidate 1
chr17_-_42019836 0.16 ENST00000225992.3
pancreatic polypeptide
chr1_-_41487415 0.16 ENST00000372611.1
schlafen-like 1
chr20_-_18447667 0.15 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr16_-_3285144 0.15 ENST00000431561.3
ENST00000396870.4
zinc finger protein 200
chr19_+_36157715 0.15 ENST00000379013.2
ENST00000222275.2
uroplakin 1A
chrX_+_70503433 0.15 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
non-POU domain containing, octamer-binding
chr11_+_60467047 0.15 ENST00000300226.2
membrane-spanning 4-domains, subfamily A, member 8
chr5_+_89770696 0.15 ENST00000504930.1
ENST00000514483.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr8_-_67525524 0.15 ENST00000517885.1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_41487383 0.15 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
schlafen-like 1
chr20_-_61885826 0.15 ENST00000370316.3
Na+/K+ transporting ATPase interacting 4
chr5_+_7869217 0.15 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr7_-_127032363 0.15 ENST00000393312.1
zinc finger protein 800
chr15_-_31453359 0.15 ENST00000542188.1
transient receptor potential cation channel, subfamily M, member 1
chr9_+_15553000 0.15 ENST00000297641.3
coiled-coil domain containing 171
chr5_+_149340282 0.15 ENST00000286298.4
solute carrier family 26 (anion exchanger), member 2
chr1_+_47799446 0.15 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.9 GO:0003095 pressure natriuresis(GO:0003095)
0.2 0.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.2 0.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 0.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.7 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.8 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.6 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.3 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0009644 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.1 0.4 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.1 0.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0033590 response to cobalamin(GO:0033590)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0072061 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0035349 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.5 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0003285 septum secundum development(GO:0003285)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.5 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.3 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 2.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.0 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404)
0.0 0.0 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 1.3 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.0 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.0 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.0 GO:0060434 bronchus morphogenesis(GO:0060434) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0002507 tolerance induction(GO:0002507)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.9 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.2 0.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.8 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0015184 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly