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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GLIS2

Z-value: 0.48

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Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
ENSG00000126603.4 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4364762_4364762,
hg19_v2_chr16_+_4382225_4382225
-0.311.3e-01Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_45973120 2.07 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr3_-_18466026 1.44 ENST00000417717.2
SATB homeobox 1
chr5_+_68788594 1.37 ENST00000396442.2
ENST00000380766.2
occludin
chr2_+_48757278 1.25 ENST00000404752.1
ENST00000406226.1
stonin 1
chr1_-_92371839 0.97 ENST00000370399.2
transforming growth factor, beta receptor III
chr22_+_31523734 0.80 ENST00000402238.1
ENST00000404453.1
ENST00000401755.1
inositol polyphosphate-5-phosphatase J
chr14_-_105635090 0.80 ENST00000331782.3
ENST00000347004.2
jagged 2
chr1_-_186649543 0.65 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr16_+_55542910 0.64 ENST00000262134.5
lysophosphatidylcholine acyltransferase 2
chr6_+_84743436 0.59 ENST00000257776.4
melanocortin 2 receptor accessory protein 2
chr14_-_54955721 0.57 ENST00000554908.1
glia maturation factor, beta
chr10_+_94608218 0.55 ENST00000371543.1
exocyst complex component 6
chr5_+_140566 0.54 ENST00000502646.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr1_-_20503917 0.52 ENST00000429261.2
phospholipase A2, group IIC
chr20_+_30598231 0.52 ENST00000300415.8
ENST00000262659.8
cerebral cavernous malformation 2-like
chrX_+_46433193 0.45 ENST00000276055.3
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr19_+_11200038 0.45 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
low density lipoprotein receptor
chr22_-_28197486 0.45 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr1_-_24127256 0.43 ENST00000418277.1
UDP-galactose-4-epimerase
chr9_+_139839711 0.42 ENST00000224181.3
complement component 8, gamma polypeptide
chr2_-_113999260 0.41 ENST00000468980.2
paired box 8
chrX_+_118108571 0.40 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr19_+_50979753 0.39 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
ER membrane protein complex subunit 10
chr17_+_61571746 0.39 ENST00000579409.1
angiotensin I converting enzyme
chr21_-_31869451 0.39 ENST00000334058.2
keratin associated protein 19-4
chr6_-_2903514 0.39 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr2_+_24272576 0.38 ENST00000380986.4
ENST00000452109.1
FK506 binding protein 1B, 12.6 kDa
chr3_-_125802765 0.38 ENST00000514891.1
ENST00000512470.1
ENST00000504035.1
ENST00000360370.4
ENST00000513723.1
ENST00000510651.1
ENST00000514333.1
solute carrier family 41, member 3
chr11_+_86748863 0.37 ENST00000340353.7
transmembrane protein 135
chr1_+_44412577 0.37 ENST00000372343.3
importin 13
chr10_-_33623564 0.37 ENST00000374875.1
ENST00000374822.4
neuropilin 1
chr19_-_2050852 0.37 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr9_-_34710066 0.37 ENST00000378792.1
ENST00000259607.2
chemokine (C-C motif) ligand 21
chr6_-_133119668 0.34 ENST00000275227.4
ENST00000538764.1
solute carrier family 18, subfamily B, member 1
chr11_+_125034586 0.34 ENST00000298282.9
PBX/knotted 1 homeobox 2
chrX_-_70474910 0.33 ENST00000373988.1
ENST00000373998.1
zinc finger, MYM-type 3
chr19_-_41859814 0.33 ENST00000221930.5
transforming growth factor, beta 1
chr3_+_44626446 0.33 ENST00000441021.1
ENST00000322734.2
zinc finger protein 660
chr11_-_2160180 0.33 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chrX_+_118108601 0.32 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr8_+_118533049 0.32 ENST00000522839.1
mediator complex subunit 30
chr10_+_94608245 0.31 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr11_+_844067 0.31 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chr20_-_30310797 0.31 ENST00000422920.1
BCL2-like 1
chr3_-_125803105 0.31 ENST00000346785.5
ENST00000315891.6
solute carrier family 41, member 3
chr4_-_107237340 0.31 ENST00000394706.3
TBC1 domain containing kinase
chr8_-_29120580 0.31 ENST00000524189.1
kinesin family member 13B
chr4_-_107237374 0.30 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBC1 domain containing kinase
chr19_+_49891475 0.30 ENST00000447857.3
coiled-coil domain containing 155
chr20_-_30458019 0.30 ENST00000486996.1
ENST00000398084.2
dual specificity phosphatase 15
chr6_-_119670919 0.28 ENST00000368468.3
mannosidase, alpha, class 1A, member 1
chr17_-_5138099 0.28 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr9_-_35112376 0.28 ENST00000488109.2
family with sequence similarity 214, member B
chr10_-_75634219 0.28 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr2_+_24272543 0.27 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr22_-_38794490 0.27 ENST00000400206.2
casein kinase 1, epsilon
chr15_-_31283798 0.27 ENST00000435680.1
ENST00000425768.1
myotubularin related protein 10
chr3_-_197282821 0.27 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
3-hydroxybutyrate dehydrogenase, type 1
chr15_-_90233866 0.27 ENST00000561257.1
peroxisomal biogenesis factor 11 alpha
chr22_-_21482046 0.26 ENST00000419447.1
POM121 transmembrane nucleoporin-like 7
chr11_+_31531291 0.26 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr22_-_50700140 0.26 ENST00000215659.8
mitogen-activated protein kinase 12
chr19_+_10527449 0.26 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr14_+_23842018 0.26 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr16_-_4664860 0.26 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBA-like domain containing 1
chr9_+_134103496 0.25 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr20_-_30310656 0.25 ENST00000376055.4
BCL2-like 1
chr14_-_105531759 0.24 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
G protein-coupled receptor 132
chr11_-_31531121 0.24 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_-_42759300 0.24 ENST00000222329.4
Ets2 repressor factor
chrX_-_10557949 0.23 ENST00000380780.1
midline 1 (Opitz/BBB syndrome)
chr12_+_57853918 0.23 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr19_+_36602104 0.23 ENST00000585332.1
ENST00000262637.4
ovo-like zinc finger 3
chr16_-_3306587 0.23 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr19_-_17185848 0.23 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr19_+_45409011 0.22 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr20_-_30310693 0.22 ENST00000307677.4
ENST00000420653.1
BCL2-like 1
chr10_+_14880287 0.21 ENST00000437161.2
heat shock 70kDa protein 14
chr16_-_49890016 0.21 ENST00000563137.2
zinc finger protein 423
chr19_+_1905365 0.20 ENST00000329478.2
ENST00000602400.1
ENST00000409472.1
adenosine deaminase, tRNA-specific 3
secretory carrier membrane protein 4
chr2_+_181845074 0.20 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
ubiquitin-conjugating enzyme E2E 3
chr1_+_64936428 0.20 ENST00000371073.2
ENST00000290039.5
cache domain containing 1
chr1_-_54411255 0.20 ENST00000371377.3
heat shock protein family B (small), member 11
chr14_-_23426270 0.20 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr12_+_57998400 0.20 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)
chr20_+_33462888 0.20 ENST00000336325.4
acyl-CoA synthetase short-chain family member 2
chr14_-_23426322 0.19 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr14_-_23426337 0.19 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr1_+_150980889 0.19 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
prune exopolyphosphatase
chr2_+_131113609 0.19 ENST00000347849.3
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr11_-_76381029 0.19 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr11_+_66624527 0.19 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr22_+_31489344 0.19 ENST00000404574.1
smoothelin
chr11_-_1036706 0.19 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chr16_-_67185117 0.19 ENST00000449549.3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr7_+_133812052 0.18 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr9_-_98279241 0.18 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
patched 1
chr19_-_46405861 0.18 ENST00000322217.5
Myb-related transcription factor, partner of profilin
chr19_-_19006920 0.18 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr4_-_106394866 0.18 ENST00000502596.1
pyrophosphatase (inorganic) 2
chr17_-_76921459 0.18 ENST00000262768.7
TIMP metallopeptidase inhibitor 2
chr15_+_85359911 0.18 ENST00000258888.5
alpha-kinase 3
chr17_+_78075361 0.18 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr15_-_90234006 0.17 ENST00000300056.3
ENST00000559170.1
peroxisomal biogenesis factor 11 alpha
chr8_+_1772132 0.17 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
Rho guanine nucleotide exchange factor (GEF) 10
chr11_+_121447469 0.17 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_-_28518153 0.17 ENST00000356897.1
interleukin 27
chr12_+_57998595 0.17 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
deltex homolog 3 (Drosophila)
chr20_-_35492048 0.17 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr2_+_169312350 0.17 ENST00000305747.6
ceramide synthase 6
chrX_+_152240819 0.17 ENST00000421798.3
ENST00000535416.1
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chrX_+_53449839 0.17 ENST00000457095.1
RIB43A domain with coiled-coils 1
chr16_+_3070356 0.16 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
tumor necrosis factor receptor superfamily, member 12A
chr7_-_4998802 0.16 ENST00000406755.1
ENST00000404774.3
ENST00000401401.3
monocyte to macrophage differentiation-associated 2
chr7_+_140373619 0.16 ENST00000483369.1
aarF domain containing kinase 2
chr16_+_3070313 0.16 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr12_-_133263893 0.16 ENST00000535270.1
ENST00000320574.5
polymerase (DNA directed), epsilon, catalytic subunit
chr2_+_131113580 0.16 ENST00000175756.5
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr1_-_201123546 0.16 ENST00000435310.1
ENST00000485839.2
ENST00000367330.1
transmembrane protein 9
chr19_-_3061397 0.16 ENST00000586839.1
amino-terminal enhancer of split
chr9_+_127539481 0.16 ENST00000373580.3
olfactomedin-like 2A
chr11_+_66045634 0.16 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr16_+_765092 0.16 ENST00000568223.2
meteorin, glial cell differentiation regulator
chr2_+_108905325 0.15 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
sulfotransferase family, cytosolic, 1C, member 2
chr15_+_91478493 0.15 ENST00000418476.2
unc-45 homolog A (C. elegans)
chr19_+_11909329 0.15 ENST00000323169.5
ENST00000450087.1
zinc finger protein 491
chr1_-_201123586 0.15 ENST00000414605.2
ENST00000367334.5
ENST00000367332.1
transmembrane protein 9
chr1_+_201979645 0.15 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_-_39282221 0.15 ENST00000453413.2
potassium channel, subfamily K, member 17
chr10_+_70320413 0.15 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr17_+_7788104 0.14 ENST00000380358.4
chromodomain helicase DNA binding protein 3
chr5_-_176836577 0.14 ENST00000253496.3
coagulation factor XII (Hageman factor)
chr3_-_28390581 0.14 ENST00000479665.1
5-azacytidine induced 2
chr19_+_17337473 0.14 ENST00000598068.1
occludin/ELL domain containing 1
chr7_-_752577 0.14 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_32110467 0.14 ENST00000440872.2
ENST00000373703.4
penta-EF-hand domain containing 1
chr17_-_27224621 0.14 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
flotillin 2
chr7_+_140372953 0.14 ENST00000072869.4
ENST00000476491.1
aarF domain containing kinase 2
chr19_+_41103063 0.14 ENST00000308370.7
latent transforming growth factor beta binding protein 4
chr19_-_18653781 0.14 ENST00000596558.2
ENST00000453489.2
FK506 binding protein 8, 38kDa
chr7_-_130080977 0.14 ENST00000223208.5
centrosomal protein 41kDa
chr21_-_45671014 0.13 ENST00000436357.1
DNA (cytosine-5-)-methyltransferase 3-like
chrX_-_102319092 0.13 ENST00000372728.3
brain expressed, X-linked 1
chr21_+_42539701 0.13 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
beta-site APP-cleaving enzyme 2
chr19_+_14640372 0.13 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
trans-2,3-enoyl-CoA reductase
chr1_+_41157421 0.13 ENST00000372654.1
nuclear transcription factor Y, gamma
chr11_-_119217365 0.13 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chr6_-_39282329 0.13 ENST00000373231.4
potassium channel, subfamily K, member 17
chr1_-_54411240 0.13 ENST00000371378.2
heat shock protein family B (small), member 11
chr19_+_17337406 0.13 ENST00000597836.1
occludin/ELL domain containing 1
chr20_-_30433396 0.13 ENST00000375978.3
forkhead box S1
chr5_+_139027877 0.13 ENST00000302517.3
CXXC finger protein 5
chr19_+_56159509 0.13 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
coiled-coil domain containing 106
chr3_-_48470838 0.13 ENST00000358459.4
ENST00000358536.4
plexin B1
chr7_+_2671663 0.13 ENST00000407643.1
tweety family member 3
chr20_+_57226284 0.13 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
syntaxin 16
chr19_+_55105085 0.13 ENST00000251372.3
ENST00000453777.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr2_-_89310012 0.12 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr19_-_54850417 0.12 ENST00000291759.4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr6_-_32908765 0.12 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr2_-_179343268 0.12 ENST00000424785.2
FK506 binding protein 7
chr20_+_57226841 0.12 ENST00000358029.4
ENST00000361830.3
syntaxin 16
chr22_-_19974616 0.12 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
armadillo repeat gene deleted in velocardiofacial syndrome
chr3_-_28390298 0.12 ENST00000457172.1
5-azacytidine induced 2
chr2_-_85829496 0.12 ENST00000409668.1
transmembrane protein 150A
chr1_-_40157345 0.12 ENST00000372844.3
hippocalcin like 4
chr1_+_150954493 0.12 ENST00000368947.4
annexin A9
chrX_+_153656978 0.12 ENST00000369762.2
ENST00000422890.1
ATPase, H+ transporting, lysosomal accessory protein 1
chr6_+_17393839 0.12 ENST00000489374.1
ENST00000378990.2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_+_811073 0.11 ENST00000382862.3
ENST00000563651.1
mesothelin
chr1_+_41157671 0.11 ENST00000534399.1
ENST00000372653.1
nuclear transcription factor Y, gamma
chr19_-_41256207 0.11 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr8_+_38243951 0.11 ENST00000297720.5
leucine zipper-EF-hand containing transmembrane protein 2
chr19_-_35454953 0.11 ENST00000404801.1
zinc finger protein 792
chr6_+_33048222 0.11 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chrX_+_54834159 0.11 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
melanoma antigen family D, 2
chr13_-_42535214 0.11 ENST00000379310.3
ENST00000281496.6
von Willebrand factor A domain containing 8
chr3_-_11888246 0.11 ENST00000455809.1
ENST00000444133.2
ENST00000273037.5
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
chr11_-_64510409 0.11 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_2702681 0.11 ENST00000382159.3
guanine nucleotide binding protein (G protein), gamma 7
chr20_-_52687059 0.11 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr12_+_50451331 0.11 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr17_+_38278530 0.11 ENST00000398532.4
male-specific lethal 1 homolog (Drosophila)
chr19_-_821931 0.11 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chr1_-_156675368 0.11 ENST00000368222.3
cellular retinoic acid binding protein 2
chr6_+_28109703 0.11 ENST00000457389.2
ENST00000330236.6
zinc finger with KRAB and SCAN domains 8
chr3_+_52017454 0.10 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
aminoacylase 1
chrX_+_53449805 0.10 ENST00000414955.2
RIB43A domain with coiled-coils 1
chr10_-_104179682 0.10 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr1_-_242162375 0.10 ENST00000357246.3
microtubule-associated protein 1 light chain 3 gamma
chr21_-_39288743 0.10 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr5_-_1524015 0.10 ENST00000283415.3
lysophosphatidylcholine acyltransferase 1
chr19_+_56159362 0.10 ENST00000593069.1
ENST00000308964.3
coiled-coil domain containing 106
chr19_-_4517613 0.10 ENST00000301286.3
perilipin 4
chr11_-_796197 0.10 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr17_+_75315534 0.10 ENST00000590294.1
ENST00000329047.8
septin 9
chr17_+_48503603 0.10 ENST00000502667.1
acyl-CoA synthetase family member 2
chr2_-_208490027 0.10 ENST00000458426.1
ENST00000406927.2
ENST00000425132.1
methyltransferase like 21A
chr11_+_64058758 0.10 ENST00000538767.1
potassium channel, subfamily K, member 4
chr17_+_73996987 0.10 ENST00000588812.1
ENST00000448471.1
cyclin-dependent kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.4 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.4 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:1900126 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.8 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.4 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.8 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.4 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.1 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.4 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:0036146 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 0.2 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.2 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.3 GO:0009624 response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.3 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.5 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.6 GO:0097009 energy homeostasis(GO:0097009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.6 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.8 GO:0034485 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.0 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins