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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GMEB2

Z-value: 0.99

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Transcription factors associated with GMEB2

Gene Symbol Gene ID Gene Info
ENSG00000101216.6 glucocorticoid modulatory element binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB2hg19_v2_chr20_-_62258394_62258464-0.096.6e-01Click!

Activity profile of GMEB2 motif

Sorted Z-values of GMEB2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_78511586 2.95 ENST00000370759.3
GIPC PDZ domain containing family, member 2
chr10_+_35415719 1.93 ENST00000474362.1
ENST00000374721.3
cAMP responsive element modulator
chr11_-_2906979 1.89 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr17_-_58469591 1.68 ENST00000589335.1
ubiquitin specific peptidase 32
chr10_-_131762105 1.66 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr3_-_52479043 1.65 ENST00000231721.2
ENST00000475739.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr10_+_35416090 1.61 ENST00000354759.3
cAMP responsive element modulator
chr4_+_42399856 1.55 ENST00000319234.4
shisa family member 3
chr11_-_33913708 1.55 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr10_+_35415978 1.50 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
cAMP responsive element modulator
chrX_+_55478538 1.46 ENST00000342972.1
melanoma antigen family H, 1
chr1_+_61547894 1.44 ENST00000403491.3
nuclear factor I/A
chr14_-_53019211 1.42 ENST00000557374.1
ENST00000281741.4
thioredoxin domain containing 16
chr1_+_92495528 1.32 ENST00000370383.4
epoxide hydrolase 4
chr8_-_125384927 1.31 ENST00000297632.6
transmembrane protein 65
chr12_+_53440753 1.30 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr10_+_35416223 1.29 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr2_-_43453734 1.27 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr2_+_61108771 1.18 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_+_43328004 1.17 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr11_+_31531291 1.13 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr16_-_4588469 1.12 ENST00000588381.1
ENST00000563332.2
cell death-inducing p53 target 1
chr11_-_2160180 1.09 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr10_-_33625154 1.06 ENST00000265371.4
neuropilin 1
chr9_+_43684902 1.06 ENST00000377564.3
ENST00000276974.6
contactin associated protein-like 3B
chr17_+_56769924 1.06 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51 paralog C
chr7_+_12726474 1.04 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ADP-ribosylation factor-like 4A
chr2_+_189156721 1.01 ENST00000409927.1
ENST00000409805.1
GULP, engulfment adaptor PTB domain containing 1
chr12_+_27396901 1.00 ENST00000541191.1
ENST00000389032.3
serine/threonine kinase 38 like
chr2_+_189156586 1.00 ENST00000409830.1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_177053307 0.98 ENST00000331462.4
homeobox D1
chr6_-_41909191 0.97 ENST00000512426.1
ENST00000372987.4
cyclin D3
chr11_-_31531121 0.95 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_+_25992884 0.94 ENST00000606723.2
U91328.19
chr1_+_90098606 0.93 ENST00000370454.4
leucine rich repeat containing 8 family, member C
chr2_+_189156389 0.91 ENST00000409843.1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_58223228 0.85 ENST00000478253.1
ENST00000295962.4
abhydrolase domain containing 6
chr2_+_61108650 0.84 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr16_-_67217844 0.83 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895-like
chr11_-_124981475 0.82 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr17_+_75137034 0.82 ENST00000436233.4
ENST00000443798.4
SEC14-like 1 (S. cerevisiae)
chr4_+_170541660 0.82 ENST00000513761.1
ENST00000347613.4
chloride channel, voltage-sensitive 3
chr13_-_33112823 0.81 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr19_+_10527449 0.81 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr7_+_139025875 0.80 ENST00000297534.6
chromosome 7 open reading frame 55
chr12_+_13349650 0.80 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
epithelial membrane protein 1
chr17_-_73975444 0.79 ENST00000293217.5
ENST00000537812.1
acyl-CoA oxidase 1, palmitoyl
chr3_-_122512619 0.78 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr2_-_27712583 0.78 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
intraflagellar transport 172 homolog (Chlamydomonas)
chr17_+_75136980 0.77 ENST00000585618.1
ENST00000413679.2
SEC14-like 1 (S. cerevisiae)
chr6_-_52860171 0.77 ENST00000370963.4
glutathione S-transferase alpha 4
chr1_+_66797687 0.76 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr1_+_6845578 0.75 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr16_-_4588822 0.75 ENST00000564828.1
cell death-inducing p53 target 1
chr8_-_77912431 0.75 ENST00000357039.4
ENST00000522527.1
peroxisomal biogenesis factor 2
chr18_-_2571437 0.74 ENST00000574676.1
ENST00000574538.1
ENST00000319888.6
methyltransferase like 4
chr2_-_222436988 0.73 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPH receptor A4
chr21_+_38445539 0.72 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr13_-_78492927 0.72 ENST00000334286.5
endothelin receptor type B
chr17_-_15902951 0.71 ENST00000472495.1
zinc finger, SWIM-type containing 7
chr8_-_27630102 0.71 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
coiled-coil domain containing 25
chr1_+_42921761 0.71 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr22_-_38902300 0.71 ENST00000403230.1
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr4_+_170541678 0.71 ENST00000360642.3
ENST00000512813.1
chloride channel, voltage-sensitive 3
chr7_+_12250833 0.70 ENST00000396668.3
transmembrane protein 106B
chr7_+_120590803 0.70 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr16_-_88772670 0.70 ENST00000562544.1
ring finger protein 166
chr2_-_44588624 0.69 ENST00000438314.1
ENST00000409936.1
prolyl endopeptidase-like
chr2_+_109335929 0.69 ENST00000283195.6
RAN binding protein 2
chr20_-_35402123 0.69 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1, MIS12 kinetochore complex component
chr19_+_18118972 0.69 ENST00000593560.2
ENST00000222250.4
arrestin domain containing 2
chr1_-_229644034 0.68 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
nucleoporin 133kDa
chr17_+_25621102 0.67 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WD repeat and SOCS box containing 1
chr19_+_35417798 0.67 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
zinc finger protein 30
chr1_-_154909329 0.67 ENST00000368467.3
phosphomevalonate kinase
chr19_+_35417939 0.67 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr12_-_42877408 0.66 ENST00000552240.1
prickle homolog 1 (Drosophila)
chr16_-_4588762 0.66 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
cell death-inducing p53 target 1
chr11_-_116968987 0.65 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr5_-_76383133 0.65 ENST00000255198.2
zinc finger, BED-type containing 3
chr10_+_35464513 0.64 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
cAMP responsive element modulator
chr14_-_76127519 0.63 ENST00000256319.6
chromosome 14 open reading frame 1
chr2_+_44589036 0.62 ENST00000402247.1
ENST00000407131.1
ENST00000403853.3
ENST00000378494.3
calmodulin-lysine N-methyltransferase
chr2_-_44588893 0.61 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
prolyl endopeptidase-like
chr5_+_175298573 0.60 ENST00000512824.1
complexin 2
chr2_-_202645835 0.60 ENST00000264276.6
amyotrophic lateral sclerosis 2 (juvenile)
chr1_-_155881156 0.60 ENST00000539040.1
ENST00000368323.3
Ras-like without CAAX 1
chr6_+_127587755 0.60 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr9_-_77643307 0.60 ENST00000376834.3
ENST00000376830.3
chromosome 9 open reading frame 41
chr15_+_49170083 0.60 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr1_+_74663896 0.59 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr12_-_46121554 0.59 ENST00000609803.1
long intergenic non-protein coding RNA 938
chr6_+_24495067 0.59 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr2_+_42721689 0.58 ENST00000405592.1
metastasis associated 1 family, member 3
chr2_-_44588679 0.58 ENST00000409411.1
prolyl endopeptidase-like
chrX_-_77150911 0.58 ENST00000373336.3
magnesium transporter 1
chr2_-_44588694 0.57 ENST00000409957.1
prolyl endopeptidase-like
chr6_-_144329531 0.57 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr2_-_85829496 0.57 ENST00000409668.1
transmembrane protein 150A
chrX_+_55026763 0.57 ENST00000374987.3
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr10_+_18948311 0.57 ENST00000377275.3
ADP-ribosylation factor-like 5B
chr2_-_85829811 0.56 ENST00000306353.3
transmembrane protein 150A
chr2_-_220083671 0.56 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_246670519 0.55 ENST00000388985.4
ENST00000490107.1
SET and MYND domain containing 3
chr10_+_22610124 0.54 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr2_-_45838374 0.54 ENST00000263736.4
S1 RNA binding domain 1
chr10_-_50747064 0.54 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr1_+_87380299 0.54 ENST00000370551.4
ENST00000370550.5
heparan sulfate 2-O-sulfotransferase 1
chr1_+_220960033 0.53 ENST00000366910.5
mitochondrial amidoxime reducing component 1
chr1_+_243419306 0.53 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
serologically defined colon cancer antigen 8
chr4_+_39460689 0.53 ENST00000381846.1
lipoic acid synthetase
chr1_-_150980828 0.53 ENST00000361936.5
ENST00000361738.6
family with sequence similarity 63, member A
chr4_+_113152978 0.52 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr15_-_55700457 0.52 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr4_-_39640513 0.52 ENST00000511809.1
ENST00000505729.1
small integral membrane protein 14
chr17_-_8059638 0.52 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr3_-_160823158 0.52 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_+_61851157 0.52 ENST00000578681.1
ENST00000583590.1
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr17_-_62097904 0.52 ENST00000583366.1
intercellular adhesion molecule 2
chr7_-_156685841 0.51 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr3_+_180319918 0.51 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
tetratricopeptide repeat domain 14
chr4_-_110651143 0.51 ENST00000243501.5
phospholipase A2, group XIIA
chr9_+_91933407 0.51 ENST00000375807.3
ENST00000339901.4
SECIS binding protein 2
chr4_-_148605265 0.50 ENST00000541232.1
ENST00000322396.6
protein arginine methyltransferase 10 (putative)
chr17_+_66511540 0.49 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr22_-_38902325 0.49 ENST00000396821.3
ENST00000381633.3
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr15_-_55700522 0.49 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr13_+_57715052 0.49 ENST00000377931.1
proline rich 20A
chr21_-_33984865 0.49 ENST00000458138.1
chromosome 21 open reading frame 59
chr14_-_103987679 0.48 ENST00000553610.1
creatine kinase, brain
chr2_-_220083692 0.48 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr9_-_125667618 0.48 ENST00000423239.2
ring finger and CCCH-type domains 2
chr11_+_95523823 0.48 ENST00000538658.1
centrosomal protein 57kDa
chr4_+_39460659 0.47 ENST00000513731.1
lipoic acid synthetase
chr21_-_33984888 0.47 ENST00000382549.4
ENST00000540881.1
chromosome 21 open reading frame 59
chr2_-_198299726 0.47 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr5_-_162887071 0.47 ENST00000302764.4
NudC domain containing 2
chrX_-_134478012 0.47 ENST00000370766.3
zinc finger protein 75D
chr3_-_160823040 0.46 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_+_63448918 0.46 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
reticulon 3
chr19_-_41903161 0.46 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr4_+_39460620 0.46 ENST00000340169.2
ENST00000261434.3
lipoic acid synthetase
chr17_+_75084717 0.46 ENST00000561721.2
ENST00000589827.1
ENST00000392476.2
SEC14-like 1 (S. cerevisiae)
chr5_-_162887054 0.46 ENST00000517501.1
NudC domain containing 2
chr17_-_15903002 0.46 ENST00000399277.1
zinc finger, SWIM-type containing 7
chrX_+_102883887 0.45 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr11_+_61583721 0.45 ENST00000257261.6
fatty acid desaturase 2
chr11_-_2162468 0.45 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr4_-_73935409 0.45 ENST00000507544.2
ENST00000295890.4
COX18 cytochrome C oxidase assembly factor
chr6_+_123110465 0.45 ENST00000539041.1
sphingomyelin phosphodiesterase, acid-like 3A
chr1_+_42922173 0.45 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr1_+_154474689 0.44 ENST00000368482.4
tudor domain containing 10
chr3_+_9975497 0.44 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
cysteine-rich with EGF-like domains 1
chr1_-_119683251 0.44 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr16_-_20753114 0.44 ENST00000396083.2
THUMP domain containing 1
chr17_-_15902903 0.44 ENST00000486655.1
zinc finger, SWIM-type containing 7
chr3_-_69129501 0.44 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr9_+_79792410 0.44 ENST00000357409.5
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr3_+_182511266 0.43 ENST00000323116.5
ENST00000493826.1
ATPase, class VI, type 11B
chr10_+_82168240 0.43 ENST00000372187.5
ENST00000372185.1
family with sequence similarity 213, member A
chr4_+_39184024 0.42 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WD repeat domain 19
chr16_+_3019246 0.42 ENST00000318782.8
ENST00000293978.8
progestin and adipoQ receptor family member IV
chr10_-_49459800 0.42 ENST00000305531.3
FERM and PDZ domain containing 2
chr5_+_140625147 0.41 ENST00000231173.3
protocadherin beta 15
chr4_-_76439483 0.41 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_-_55496174 0.41 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr10_-_18948156 0.41 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr1_-_87379785 0.41 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr16_+_19079215 0.41 ENST00000544894.2
ENST00000561858.1
coenzyme Q7 homolog, ubiquinone (yeast)
chr8_+_118533049 0.41 ENST00000522839.1
mediator complex subunit 30
chr2_-_68694390 0.41 ENST00000377957.3
F-box protein 48
chr3_+_134205000 0.41 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
centrosomal protein 63kDa
chr6_-_79944336 0.41 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chrX_-_67653614 0.41 ENST00000355520.5
oligophrenin 1
chr9_-_5833027 0.41 ENST00000339450.5
endoplasmic reticulum metallopeptidase 1
chr9_+_91933726 0.41 ENST00000534113.2
SECIS binding protein 2
chr4_-_186317034 0.41 ENST00000505916.1
LRP2 binding protein
chr1_-_713985 0.40 ENST00000428504.1
RP11-206L10.2
chrX_-_119763835 0.40 ENST00000371313.2
ENST00000304661.5
C1GALT1-specific chaperone 1
chr11_+_95523621 0.40 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr7_+_102715573 0.40 ENST00000434153.1
armadillo repeat containing 10
chr2_-_107084826 0.40 ENST00000304514.7
ENST00000409886.3
RANBP2-like and GRIP domain containing 3
chr5_+_82373317 0.40 ENST00000282268.3
ENST00000338635.6
X-ray repair complementing defective repair in Chinese hamster cells 4
chr17_-_7165662 0.40 ENST00000571881.2
ENST00000360325.7
claudin 7
chr5_-_178054105 0.40 ENST00000316308.4
CDC-like kinase 4
chr1_+_150039369 0.40 ENST00000369130.3
ENST00000369128.5
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr15_-_55700216 0.39 ENST00000569205.1
cell cycle progression 1
chr3_+_134204881 0.39 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
centrosomal protein 63kDa
chr1_-_15850676 0.39 ENST00000440484.1
ENST00000333868.5
caspase 9, apoptosis-related cysteine peptidase
chr20_+_54933971 0.39 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr8_-_37594944 0.39 ENST00000330539.1
Uncharacterized protein
chr4_-_77135046 0.39 ENST00000264896.2
scavenger receptor class B, member 2
chr1_-_52344471 0.39 ENST00000352171.7
ENST00000354831.7
nardilysin (N-arginine dibasic convertase)
chr1_+_210001309 0.39 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chr22_+_47158578 0.38 ENST00000355704.3
TBC1 domain family, member 22A
chr2_-_88125286 0.38 ENST00000327544.6
RANBP2-like and GRIP domain containing 2
chr17_-_58469687 0.38 ENST00000590133.1
ubiquitin specific peptidase 32
chr9_+_79792269 0.38 ENST00000376634.4
ENST00000376636.3
ENST00000360280.3
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr1_-_22109484 0.38 ENST00000529637.1
ubiquitin specific peptidase 48
chr8_-_97247759 0.38 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
ubiquinol-cytochrome c reductase binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.4 2.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.1 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.3 1.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 0.9 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.3 0.8 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3 1.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.3 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.1 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 1.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 0.6 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.2 0.5 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.7 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.7 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.2 1.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.5 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.7 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.7 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.3 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.6 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.1 GO:0015871 choline transport(GO:0015871)
0.1 2.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.5 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.4 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1 6.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.8 GO:0061525 hindgut development(GO:0061525)
0.1 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825) interkinetic nuclear migration(GO:0022027)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 1.5 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:0051410 detoxification of nitrogen compound(GO:0051410)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 1.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 1.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.3 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 1.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.6 GO:0032025 response to cobalt ion(GO:0032025)
0.0 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:2000373 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.9 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 1.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.8 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 2.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.8 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 1.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.0 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.4 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0044359 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.0 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.1 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.0 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.3 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.0 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.4 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0097196 Shu complex(GO:0097196)
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 2.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.3 0.8 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 0.7 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.2 0.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 2.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.1 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.2 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.2 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 3.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 1.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 5.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.4 7.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 1.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 2.1 GO:0039552 RIG-I binding(GO:0039552)
0.3 1.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.6 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 0.6 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2 0.5 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.7 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.5 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 1.2 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 2.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 1.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.5 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) small protein activating enzyme binding(GO:0044388)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 2.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines