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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for GMEB2
Z-value: 0.99
Motif logo
Transcription factors associated with GMEB2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GMEB2
|
ENSG00000101216.6 | glucocorticoid modulatory element binding protein 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB2 | hg19_v2_chr20_-_62258394_62258464 | -0.09 | 6.6e-01 | Click! |
Activity profile of GMEB2 motif
Sorted Z-values of GMEB2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of GMEB2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:0009107 | lipoate biosynthetic process(GO:0009107) |
| 0.4 | 2.1 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.4 | 1.1 | GO:0007497 | posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100) |
| 0.3 | 1.9 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.3 | 0.9 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.3 | 0.8 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.3 | 1.1 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
| 0.3 | 0.8 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.2 | 1.1 | GO:0061552 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.2 | 1.9 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.2 | 0.6 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 0.2 | 0.5 | GO:0051780 | mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780) |
| 0.2 | 0.2 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.2 | 0.7 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.2 | 0.7 | GO:0051664 | nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664) |
| 0.2 | 1.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 0.5 | GO:0045799 | mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.2 | 0.7 | GO:2000690 | negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.2 | 1.1 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.2 | 0.5 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.2 | 0.6 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.2 | 1.2 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 0.7 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.1 | 0.4 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.1 | 1.3 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.1 | 0.6 | GO:0006696 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 0.1 | 0.5 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.1 | 0.9 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 2.1 | GO:0015871 | choline transport(GO:0015871) |
| 0.1 | 2.0 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.5 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
| 0.1 | 0.9 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.1 | 1.1 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.1 | 0.4 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 0.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 0.4 | GO:0002086 | diaphragm contraction(GO:0002086) |
| 0.1 | 0.6 | GO:0006083 | acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.1 | 0.4 | GO:1905123 | regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123) |
| 0.1 | 6.7 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 0.5 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.1 | 0.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 1.4 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 0.8 | GO:0061525 | hindgut development(GO:0061525) |
| 0.1 | 0.4 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.1 | 0.7 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 0.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 1.0 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 0.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.1 | 0.7 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.1 | 0.5 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.1 | 0.4 | GO:0038170 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.1 | 0.3 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.1 | 0.9 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 1.3 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 1.5 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 0.5 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 0.3 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.1 | 0.6 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.1 | 0.2 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.1 | 0.5 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) interkinetic nuclear migration(GO:0022027) |
| 0.1 | 0.7 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.8 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 2.8 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.1 | 0.1 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
| 0.1 | 1.5 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.1 | 0.4 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.1 | 0.3 | GO:0032417 | positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.1 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.5 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) |
| 0.1 | 0.3 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.1 | 0.2 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.1 | 0.2 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.1 | 0.2 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
| 0.1 | 0.3 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.1 | 1.3 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.7 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 0.3 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.2 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 1.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.2 | GO:0019853 | L-ascorbic acid biosynthetic process(GO:0019853) |
| 0.0 | 0.2 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.0 | 0.1 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 1.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.2 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.0 | 0.1 | GO:0051257 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.0 | 0.2 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 0.0 | 0.3 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.0 | 0.2 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 1.4 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.2 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.0 | 1.3 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 0.2 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.0 | 0.6 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 0.0 | 1.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.0 | 0.3 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.0 | 0.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.0 | 0.2 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.0 | 0.3 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.1 | GO:0046833 | snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833) |
| 0.0 | 0.1 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
| 0.0 | 0.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.7 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.0 | 0.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.1 | GO:0071673 | positive regulation of smooth muscle cell chemotaxis(GO:0071673) |
| 0.0 | 0.2 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.0 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 0.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.0 | 0.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 0.6 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.0 | 0.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.8 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.1 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.0 | 0.5 | GO:0007379 | segment specification(GO:0007379) |
| 0.0 | 0.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.0 | 0.1 | GO:0032242 | regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545) |
| 0.0 | 0.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 0.9 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.2 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.3 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.0 | 0.1 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 0.0 | 0.2 | GO:2000373 | phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.0 | 0.9 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 1.1 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 0.9 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
| 0.0 | 1.4 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 0.3 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.0 | 0.8 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.0 | 0.5 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.0 | 2.2 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.3 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.3 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.4 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 2.8 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.0 | 0.1 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.3 | GO:0043382 | positive regulation of memory T cell differentiation(GO:0043382) |
| 0.0 | 0.4 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.0 | 0.1 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.0 | 0.1 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.0 | 0.5 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 0.1 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 1.0 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.3 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 0.1 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 0.1 | GO:2000395 | regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.0 | 0.1 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 0.0 | 0.2 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.0 | 0.2 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 0.1 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.0 | 0.2 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 0.3 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 0.1 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.0 | 0.2 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.0 | 0.0 | GO:0046103 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.0 | 0.4 | GO:0036344 | platelet morphogenesis(GO:0036344) |
| 0.0 | 0.1 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.0 | 0.2 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.0 | 0.1 | GO:0010635 | regulation of mitochondrial fusion(GO:0010635) |
| 0.0 | 0.6 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.7 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.0 | 0.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 0.1 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.0 | 0.2 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 0.2 | GO:0046146 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.0 | 0.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 0.1 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.0 | 0.5 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 0.1 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 0.3 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.2 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.0 | 0.1 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 0.1 | GO:0030047 | actin modification(GO:0030047) |
| 0.0 | 0.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.1 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.3 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.3 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.0 | 0.1 | GO:0044359 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.0 | 0.0 | GO:0034552 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 0.0 | 0.9 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.9 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.0 | 0.1 | GO:0006294 | nucleotide-excision repair, preincision complex assembly(GO:0006294) |
| 0.0 | 0.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.0 | 0.3 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
| 0.0 | 0.4 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.0 | 1.0 | GO:0000724 | double-strand break repair via homologous recombination(GO:0000724) |
| 0.0 | 0.5 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.0 | 0.3 | GO:0036119 | response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.0 | 0.1 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.0 | 0.0 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.0 | 0.0 | GO:0006850 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 0.0 | 0.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.1 | GO:0097152 | mesenchymal cell apoptotic process(GO:0097152) |
| 0.0 | 1.0 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.5 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.0 | 0.4 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.0 | 0.1 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.0 | 0.1 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.0 | 0.1 | GO:0071028 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.0 | 0.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.5 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.0 | 0.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.3 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.6 | GO:0097196 | Shu complex(GO:0097196) |
| 0.3 | 0.9 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.3 | 2.5 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.3 | 0.8 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
| 0.2 | 0.7 | GO:0000939 | nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939) |
| 0.2 | 0.8 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.2 | 2.0 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 1.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.6 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 0.4 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.1 | 0.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.1 | 0.4 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.7 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 1.1 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.3 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.1 | 1.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 0.7 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.0 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 0.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 0.2 | GO:0097134 | Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134) |
| 0.1 | 0.6 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.1 | 0.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.1 | 0.3 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.1 | 0.2 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.1 | 0.2 | GO:0032173 | septin ring(GO:0005940) septin collar(GO:0032173) |
| 0.1 | 0.2 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.1 | 0.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 0.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 0.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.1 | 0.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 0.3 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.1 | 0.5 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.3 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
| 0.0 | 0.5 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 1.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.3 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 0.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 0.4 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.1 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.0 | 0.5 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.7 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.5 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.5 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.7 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.6 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.3 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.2 | GO:0072357 | glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.5 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.2 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 0.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.1 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.0 | 0.3 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.1 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 3.0 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.5 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.5 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.0 | 0.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.7 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 1.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.2 | GO:0097413 | Lewy body(GO:0097413) |
| 0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 1.0 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.3 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 0.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.0 | 0.5 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.1 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.4 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 5.9 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 1.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.1 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.0 | 0.1 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 0.0 | 0.4 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.1 | GO:0000801 | central element(GO:0000801) |
| 0.0 | 0.2 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 0.3 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 1.4 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.3 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:0016992 | lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283) |
| 0.4 | 7.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.4 | 1.2 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.4 | 1.1 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.3 | 1.0 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
| 0.3 | 2.1 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.3 | 1.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 0.8 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.2 | 0.6 | GO:0035034 | histone acetyltransferase regulator activity(GO:0035034) |
| 0.2 | 0.6 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 0.2 | 0.5 | GO:0015130 | mevalonate transmembrane transporter activity(GO:0015130) |
| 0.2 | 0.5 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.1 | 0.7 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.1 | 0.4 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.1 | 0.9 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 0.5 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.1 | 1.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 0.4 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.1 | 1.1 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 0.3 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.1 | 0.5 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 0.5 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.1 | 1.1 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 0.8 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.1 | 1.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 2.5 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 0.4 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.1 | 1.9 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.8 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.1 | 0.3 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 0.3 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.1 | 0.2 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.1 | 1.4 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.3 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.1 | 0.3 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
| 0.1 | 1.0 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.4 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 0.6 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 0.8 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.2 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.1 | 0.2 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 0.1 | 1.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.2 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 0.5 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 0.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.5 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
| 0.1 | 1.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 0.2 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.1 | 0.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 0.2 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.1 | 2.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.6 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.1 | 0.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.1 | 0.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.1 | 0.2 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.0 | 0.1 | GO:0031531 | thyrotropin-releasing hormone receptor binding(GO:0031531) |
| 0.0 | 0.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 1.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.5 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.1 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.0 | 0.6 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 0.1 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.4 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 1.6 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.7 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.2 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.5 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) |
| 0.0 | 0.1 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.0 | 0.2 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.0 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 1.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.2 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.1 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) small protein activating enzyme binding(GO:0044388) |
| 0.0 | 1.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 1.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.5 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.2 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.7 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.0 | 0.1 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.0 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.1 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.1 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.0 | 0.3 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.4 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.0 | 0.4 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.0 | 0.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.1 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.0 | 0.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 1.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.9 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.1 | GO:0016160 | amylase activity(GO:0016160) |
| 0.0 | 0.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.1 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.1 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 0.0 | 0.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.0 | 0.1 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.0 | 0.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.5 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.0 | 0.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.1 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 0.5 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.1 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.0 | 0.2 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 0.2 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.0 | 0.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.1 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.0 | 0.1 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.1 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.2 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.0 | 0.1 | GO:0001016 | RNA polymerase III regulatory region DNA binding(GO:0001016) |
| 0.0 | 0.1 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 0.4 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 1.3 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.0 | 0.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.4 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.1 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 3.6 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 1.1 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.0 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 2.8 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.1 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.0 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.6 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.6 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 1.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.1 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 0.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.6 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.5 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.6 | PID ENDOTHELIN PATHWAY | Endothelins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 1.2 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.1 | 1.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.1 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 2.0 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 0.3 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.0 | 0.8 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.7 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.9 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 0.6 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.5 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 1.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.5 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.5 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.6 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.2 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 1.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.7 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.0 | 1.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 1.1 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.0 | 2.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.3 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 0.6 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.5 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.3 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.8 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.4 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 0.7 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.0 | 0.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.1 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.0 | 0.6 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.5 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.1 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.0 | 0.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.1 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |