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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GSC_GSC2

Z-value: 0.52

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Transcription factors associated with GSC_GSC2

Gene Symbol Gene ID Gene Info
GSC
ENSG00000133937.3 goosecoid homeobox
GSC2
ENSG00000063515.2 goosecoid homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GSC2hg19_v2_chr22_-_19137796_19137796-0.077.5e-01Click!
GSChg19_v2_chr14_-_95236551_952365760.039.0e-01Click!

Activity profile of GSC_GSC2 motif

Sorted Z-values of GSC_GSC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_65583561 0.95 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chrX_+_135279179 0.92 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr19_+_2476116 0.88 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr11_+_33563821 0.87 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr8_-_80993010 0.87 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr12_-_2027639 0.82 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr17_-_14683517 0.76 ENST00000379640.1
AC005863.1
AC005863.1
chr17_+_4643337 0.67 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr10_-_126716459 0.60 ENST00000309035.6
CTBP2
C-terminal binding protein 2
chr17_+_4643300 0.59 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr1_+_153651078 0.58 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr9_+_2015335 0.55 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_170541835 0.49 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr8_+_70378852 0.47 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chrX_+_100333709 0.46 ENST00000372930.4
TMEM35
transmembrane protein 35
chr1_+_162351503 0.45 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr10_-_126849588 0.45 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chrX_-_24665208 0.45 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_-_4643114 0.42 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chrX_-_10588459 0.41 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr9_-_13279563 0.40 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr2_+_189156721 0.40 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_189156586 0.39 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_-_39288092 0.39 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr15_-_52483566 0.38 ENST00000261837.7
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr5_+_53813536 0.38 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chrX_-_10588595 0.37 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr6_+_35310312 0.37 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr1_+_114522049 0.36 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr9_-_13279589 0.35 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr2_-_29297127 0.34 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chrX_-_21676442 0.33 ENST00000379499.2
KLHL34
kelch-like family member 34
chr4_+_170541678 0.30 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr7_-_120497178 0.29 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr1_-_21606013 0.29 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr2_+_189156389 0.28 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_+_170541660 0.27 ENST00000513761.1
ENST00000347613.4
CLCN3
chloride channel, voltage-sensitive 3
chr6_+_130339710 0.27 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr17_-_4689649 0.27 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr14_-_101034407 0.25 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr20_-_18774614 0.24 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chrX_+_135278908 0.24 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr11_-_62752162 0.24 ENST00000458333.2
ENST00000421062.2
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr6_+_35310391 0.23 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr9_+_17134980 0.23 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr17_-_38859996 0.22 ENST00000264651.2
KRT24
keratin 24
chr1_-_201140673 0.22 ENST00000367333.2
TMEM9
transmembrane protein 9
chr19_+_46001697 0.22 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr12_+_6949964 0.21 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr13_+_73632897 0.21 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr17_-_4806369 0.21 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr1_+_156117149 0.21 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_-_76155700 0.20 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr18_-_40857493 0.20 ENST00000255224.3
SYT4
synaptotagmin IV
chr17_+_48911942 0.20 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr2_+_120770581 0.20 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr11_-_62783276 0.19 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr10_-_104178857 0.19 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr1_-_160313025 0.19 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr11_-_76155618 0.18 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr3_-_54962100 0.18 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr14_+_57671888 0.18 ENST00000391612.1
AL391152.1
AL391152.1
chr1_+_17248418 0.17 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr10_-_49482907 0.17 ENST00000374201.3
ENST00000407470.4
FRMPD2
FERM and PDZ domain containing 2
chrX_+_107069063 0.17 ENST00000262843.6
MID2
midline 2
chr17_-_4689727 0.17 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr3_-_49058479 0.16 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr11_-_8680383 0.16 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr9_+_116298778 0.16 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr16_-_29874462 0.15 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr9_+_75229616 0.15 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr6_+_34433844 0.15 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr3_-_98241358 0.15 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr21_-_35016231 0.15 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr9_+_103204553 0.14 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_40555176 0.14 ENST00000338305.6
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr16_-_29875057 0.14 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr6_-_29399744 0.14 ENST00000377154.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr22_+_29664305 0.13 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWSR1
EWS RNA-binding protein 1
chr22_-_29663954 0.13 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr14_-_71107921 0.13 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr11_-_130184555 0.13 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr13_-_95131923 0.13 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr20_+_59654146 0.13 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr13_-_62001982 0.12 ENST00000409186.1
PCDH20
protocadherin 20
chr2_+_120770686 0.12 ENST00000331393.4
ENST00000443124.1
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr13_+_76445187 0.12 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr5_+_161274940 0.12 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_244214577 0.12 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr14_-_106967788 0.11 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chrX_-_24665353 0.11 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr11_-_67120974 0.11 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr12_-_53171128 0.11 ENST00000332411.2
KRT76
keratin 76
chr2_+_120517174 0.11 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr1_+_244816237 0.11 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chrX_-_6146876 0.10 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr11_-_119217365 0.10 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
MFRP
C1QTNF5
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chr7_-_138482849 0.10 ENST00000353492.4
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr12_-_55375622 0.10 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr14_+_21785693 0.10 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chr7_-_138482933 0.09 ENST00000310018.2
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr13_+_36050881 0.09 ENST00000537702.1
NBEA
neurobeachin
chr1_+_145413268 0.09 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr18_-_24443151 0.09 ENST00000440832.3
AQP4
aquaporin 4
chr11_-_47198380 0.09 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr7_-_97881429 0.09 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr15_+_96876340 0.09 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_62783303 0.09 ENST00000336232.2
ENST00000430500.2
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr19_-_49560987 0.08 ENST00000596965.1
CGB7
chorionic gonadotropin, beta polypeptide 7
chr8_+_55528627 0.08 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_+_161275320 0.08 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_+_73521763 0.08 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr19_+_14672755 0.08 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr4_-_147443043 0.08 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr11_-_67290867 0.08 ENST00000353903.5
ENST00000294288.4
CABP2
calcium binding protein 2
chr2_+_219472637 0.08 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr14_+_31046959 0.08 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr18_+_61223393 0.08 ENST00000269491.1
ENST00000382768.1
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr2_+_120770645 0.08 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr2_+_128175997 0.08 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr20_-_48732472 0.07 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr4_+_169552748 0.07 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr5_+_161274685 0.07 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr13_-_31191642 0.07 ENST00000405805.1
HMGB1
high mobility group box 1
chr1_+_151682909 0.07 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chrY_+_16634483 0.07 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr11_+_61522844 0.07 ENST00000265460.5
MYRF
myelin regulatory factor
chr5_+_139781445 0.06 ENST00000532219.1
ENST00000394722.3
ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr4_-_16077741 0.06 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr3_+_49058444 0.06 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr17_-_19651668 0.06 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr15_-_31453359 0.06 ENST00000542188.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr11_+_76156045 0.06 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
C11orf30
chromosome 11 open reading frame 30
chr19_-_51538118 0.06 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr19_-_51538148 0.06 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr15_+_58430567 0.06 ENST00000536493.1
AQP9
aquaporin 9
chr9_+_17135016 0.06 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr3_+_130279178 0.06 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr6_-_41130841 0.05 ENST00000373122.4
TREM2
triggering receptor expressed on myeloid cells 2
chr15_-_31393910 0.05 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr13_+_114321463 0.05 ENST00000335678.6
GRK1
G protein-coupled receptor kinase 1
chr15_+_58430368 0.05 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr7_-_104909435 0.05 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr5_-_149324306 0.05 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chrX_+_41306575 0.05 ENST00000342595.2
ENST00000378220.1
NYX
nyctalopin
chr17_-_19651654 0.05 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr2_-_14541060 0.05 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr12_-_13248598 0.04 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr3_-_193272588 0.04 ENST00000295548.3
ATP13A4
ATPase type 13A4
chr5_+_139781393 0.04 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1
ankyrin repeat and KH domain containing 1
chr12_-_14849470 0.04 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr14_+_52327350 0.04 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chrX_+_99899180 0.04 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr15_-_31453157 0.04 ENST00000559177.1
ENST00000558445.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr7_+_73868220 0.04 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chr5_+_38258511 0.04 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr1_-_36615065 0.04 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chrX_-_49089771 0.04 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr1_+_171227069 0.04 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr4_-_76823681 0.03 ENST00000286719.7
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr5_+_173316341 0.03 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr3_-_193272741 0.03 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr7_-_155326532 0.03 ENST00000406197.1
ENST00000321736.5
CNPY1
canopy FGF signaling regulator 1
chr10_+_52750930 0.03 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chrX_-_48931648 0.03 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr19_-_49843539 0.03 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr17_-_26903900 0.03 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr5_-_150138061 0.03 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr14_-_67981870 0.03 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr19_-_42931567 0.03 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr6_-_41130914 0.03 ENST00000373113.3
ENST00000338469.3
TREM2
triggering receptor expressed on myeloid cells 2
chr4_+_159727272 0.03 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr1_+_159409512 0.02 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr11_-_65624415 0.02 ENST00000524553.1
ENST00000527344.1
CFL1
cofilin 1 (non-muscle)
chr19_-_55866061 0.02 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr10_-_74714533 0.02 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr5_+_50678921 0.02 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr7_+_73868120 0.02 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr7_-_128415844 0.02 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr17_+_38465441 0.02 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr12_-_13248562 0.02 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr11_-_62752429 0.02 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr17_+_68100989 0.02 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_65625330 0.02 ENST00000531407.1
CFL1
cofilin 1 (non-muscle)
chr17_-_7142725 0.01 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHF23
PHD finger protein 23
chr2_+_192141611 0.01 ENST00000392316.1
MYO1B
myosin IB
chr12_-_13248705 0.01 ENST00000396310.2
GSG1
germ cell associated 1
chr3_-_193272874 0.01 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr9_+_4839762 0.01 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr12_-_13248732 0.01 ENST00000396302.3
GSG1
germ cell associated 1
chr16_-_69373396 0.01 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr11_-_62752455 0.01 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr14_-_24551137 0.01 ENST00000396995.1
NRL
neural retina leucine zipper
chr16_+_58010339 0.01 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chrX_+_65382381 0.01 ENST00000519389.1
HEPH
hephaestin
chr14_-_24551195 0.01 ENST00000560550.1
NRL
neural retina leucine zipper
chr1_-_11918988 0.01 ENST00000376468.3
NPPB
natriuretic peptide B
chr18_-_70532906 0.01 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr17_+_43318434 0.01 ENST00000587489.1
FMNL1
formin-like 1
chrX_+_100645812 0.00 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.3 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.6 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.6 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.4 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions