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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for GUAAACA

Z-value: 1.06

Motif logo

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miRNA associated with seed GUAAACA

NamemiRBASE accession
hsa-miR-30a-5p
MIMAT0000087
hsa-miR-30b-5p
MIMAT0000420
hsa-miR-30c-5p
MIMAT0000244
hsa-miR-30d-5p
MIMAT0000245
hsa-miR-30e-5p
MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_58206655 3.69 ENST00000377918.3
PCDH17
protocadherin 17
chr12_-_42877764 3.53 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr10_-_131762105 3.00 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr5_-_100238956 2.66 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr4_-_149365827 2.62 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr10_-_81205373 2.16 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr15_-_52970820 2.12 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr2_-_157189180 1.98 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_134070439 1.96 ENST00000264360.5
PCDH10
protocadherin 10
chr20_+_58508817 1.94 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr18_-_22932080 1.90 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr5_+_52285144 1.84 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr7_-_27224795 1.84 ENST00000006015.3
HOXA11
homeobox A11
chr14_+_100259666 1.72 ENST00000262233.6
ENST00000334192.4
EML1
echinoderm microtubule associated protein like 1
chr8_-_103668114 1.70 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr1_+_221051699 1.66 ENST00000366903.6
HLX
H2.0-like homeobox
chr20_-_45984401 1.64 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr9_-_14314066 1.58 ENST00000397575.3
NFIB
nuclear factor I/B
chr2_-_217236750 1.48 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr8_-_124553437 1.46 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr14_-_105635090 1.37 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr17_+_42634844 1.36 ENST00000315323.3
FZD2
frizzled family receptor 2
chr18_-_29264669 1.35 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr4_-_89744457 1.31 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr18_+_60190226 1.30 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr7_+_8008418 1.30 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr6_-_16761678 1.30 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr19_+_34745442 1.26 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr15_+_41221536 1.23 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr14_-_74253948 1.22 ENST00000394071.2
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr6_+_15246501 1.22 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr19_-_11450249 1.22 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr5_-_72861484 1.21 ENST00000296785.3
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr1_+_204042723 1.20 ENST00000367204.1
SOX13
SRY (sex determining region Y)-box 13
chr3_+_110790590 1.20 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr12_-_31744031 1.19 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chrX_+_107069063 1.19 ENST00000262843.6
MID2
midline 2
chr1_+_61547894 1.18 ENST00000403491.3
NFIA
nuclear factor I/A
chr11_-_67888671 1.17 ENST00000265689.4
CHKA
choline kinase alpha
chr3_-_98312548 1.16 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr3_-_18466787 1.16 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr4_+_26862400 1.16 ENST00000467011.1
ENST00000412829.2
STIM2
stromal interaction molecule 2
chr8_+_56792377 1.15 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr14_+_57735614 1.14 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr3_+_150126101 1.14 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr2_-_198540719 1.13 ENST00000295049.4
RFTN2
raftlin family member 2
chr6_+_107811162 1.12 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr18_-_12702769 1.11 ENST00000262127.2
CEP76
centrosomal protein 76kDa
chrX_+_118108571 1.11 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr3_-_129407535 1.10 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr16_+_53088885 1.09 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_-_102268628 1.09 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_12250886 1.08 ENST00000444443.1
ENST00000396667.3
TMEM106B
transmembrane protein 106B
chrX_-_135849484 1.05 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr6_+_86159821 1.03 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr8_+_37654424 1.03 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr9_+_115513003 1.02 ENST00000374232.3
SNX30
sorting nexin family member 30
chr6_+_158957431 1.01 ENST00000367090.3
TMEM181
transmembrane protein 181
chr9_-_139440314 1.00 ENST00000277541.6
NOTCH1
notch 1
chr8_-_82754427 0.99 ENST00000353788.4
ENST00000520618.1
ENST00000518183.1
ENST00000396330.2
ENST00000519119.1
ENST00000345957.4
SNX16
sorting nexin 16
chr2_-_43453734 0.99 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr9_-_111882195 0.99 ENST00000374586.3
TMEM245
transmembrane protein 245
chr4_+_41362796 0.99 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_173684047 0.98 ENST00000546011.1
ENST00000209884.4
KLHL20
kelch-like family member 20
chr14_-_91526922 0.97 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr10_+_70320413 0.96 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr12_-_42538657 0.95 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr14_-_38725573 0.95 ENST00000342213.2
CLEC14A
C-type lectin domain family 14, member A
chr22_+_40573921 0.93 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr9_-_14693417 0.92 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr6_-_108395907 0.92 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chr1_-_45672221 0.90 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr20_-_31071239 0.90 ENST00000359676.5
C20orf112
chromosome 20 open reading frame 112
chr13_-_110438914 0.89 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr6_+_143929307 0.89 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr2_-_166651191 0.88 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr7_-_41742697 0.88 ENST00000242208.4
INHBA
inhibin, beta A
chr12_-_12419703 0.86 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr7_-_112579869 0.85 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr15_+_96873921 0.85 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_+_32288725 0.84 ENST00000315285.3
SPAST
spastin
chr5_+_36152163 0.84 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr20_+_306221 0.84 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr3_+_107241783 0.83 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr17_-_76356148 0.83 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chrX_-_33146477 0.83 ENST00000378677.2
DMD
dystrophin
chr17_-_65241281 0.82 ENST00000358691.5
ENST00000580168.1
HELZ
helicase with zinc finger
chr4_-_85887503 0.81 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr12_+_20522179 0.81 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr9_-_125590818 0.81 ENST00000259467.4
PDCL
phosducin-like
chr9_-_27573392 0.81 ENST00000380003.3
C9orf72
chromosome 9 open reading frame 72
chr12_-_80084862 0.81 ENST00000328827.4
PAWR
PRKC, apoptosis, WT1, regulator
chr9_-_80646374 0.81 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_-_27205136 0.80 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr6_-_111927449 0.80 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr10_-_33623564 0.79 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr10_-_46030841 0.79 ENST00000453424.2
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr1_-_20812690 0.79 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_-_111093406 0.78 ENST00000379671.3
NREP
neuronal regeneration related protein
chr8_-_89339705 0.77 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr2_-_209119831 0.77 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr1_+_244214577 0.76 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr17_-_61920280 0.76 ENST00000448276.2
ENST00000577990.1
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr11_+_86748863 0.75 ENST00000340353.7
TMEM135
transmembrane protein 135
chr4_+_174089904 0.75 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr19_+_13261216 0.74 ENST00000587885.1
ENST00000292433.3
IER2
immediate early response 2
chr1_-_197169672 0.74 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr9_-_127703333 0.74 ENST00000373555.4
GOLGA1
golgin A1
chr2_-_201828356 0.74 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr2_-_64371546 0.72 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr3_-_56502375 0.72 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr2_-_164592497 0.71 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr3_+_194406603 0.71 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr6_-_53409890 0.70 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr5_-_148930960 0.70 ENST00000261798.5
ENST00000377843.2
CSNK1A1
casein kinase 1, alpha 1
chr12_-_90049828 0.69 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr20_-_18038521 0.69 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr11_+_134094508 0.69 ENST00000281187.5
ENST00000525095.2
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe)
chrX_-_114468605 0.68 ENST00000538422.1
ENST00000317135.8
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr15_+_51200859 0.67 ENST00000261842.5
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr6_-_79787902 0.67 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr12_-_53893399 0.67 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr14_-_78083112 0.67 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr16_+_68119440 0.67 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_+_136289030 0.66 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr3_+_112280857 0.66 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr9_-_72287191 0.66 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr19_+_32896697 0.65 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr1_+_27114418 0.65 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr3_-_195163803 0.64 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr20_+_57226284 0.64 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16
syntaxin 16
chr2_-_100106419 0.63 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr8_+_28351707 0.63 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr12_+_72233487 0.63 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15
TBC1 domain family, member 15
chr4_-_170192185 0.63 ENST00000284637.9
SH3RF1
SH3 domain containing ring finger 1
chr14_+_96829814 0.62 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSKIP
GSK3B interacting protein
chr1_+_64936428 0.62 ENST00000371073.2
ENST00000290039.5
CACHD1
cache domain containing 1
chr2_+_120517174 0.62 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr13_-_113242439 0.61 ENST00000375669.3
ENST00000261965.3
TUBGCP3
tubulin, gamma complex associated protein 3
chr8_+_26240414 0.61 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_+_74459876 0.61 ENST00000299563.4
RNF169
ring finger protein 169
chr1_-_22109682 0.61 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr5_+_77656339 0.60 ENST00000538629.1
SCAMP1
secretory carrier membrane protein 1
chr14_+_77228532 0.60 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr3_+_25469724 0.59 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr1_-_236228403 0.59 ENST00000366595.3
NID1
nidogen 1
chr7_-_35077653 0.58 ENST00000310974.4
DPY19L1
dpy-19-like 1 (C. elegans)
chr1_+_70876891 0.58 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr5_+_122110691 0.58 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2
sorting nexin 2
chr10_+_89264625 0.58 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr11_+_22688150 0.58 ENST00000454584.2
GAS2
growth arrest-specific 2
chr3_+_58223228 0.58 ENST00000478253.1
ENST00000295962.4
ABHD6
abhydrolase domain containing 6
chr1_+_120839005 0.57 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr4_-_110651143 0.57 ENST00000243501.5
PLA2G12A
phospholipase A2, group XIIA
chr15_-_72490114 0.56 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr19_-_33716750 0.56 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chrX_-_74376108 0.55 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr15_-_65579177 0.55 ENST00000444347.2
ENST00000261888.6
PARP16
poly (ADP-ribose) polymerase family, member 16
chr12_+_111843749 0.55 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr7_+_65338230 0.55 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr6_+_121756809 0.54 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr17_-_37557846 0.54 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr1_+_117910047 0.53 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr2_-_70475730 0.53 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr3_-_134093395 0.53 ENST00000249883.5
AMOTL2
angiomotin like 2
chr15_+_85359911 0.52 ENST00000258888.5
ALPK3
alpha-kinase 3
chr13_+_33160553 0.52 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr5_+_176560742 0.52 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr1_+_147013182 0.51 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr2_+_233562015 0.51 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr11_-_116968987 0.51 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr20_+_54933971 0.50 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr5_+_53813536 0.50 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
SNX18
sorting nexin 18
chr3_+_142838091 0.50 ENST00000309575.3
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr8_+_92082424 0.50 ENST00000285420.4
ENST00000404789.3
OTUD6B
OTU domain containing 6B
chr7_-_130080977 0.49 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr6_-_52441713 0.49 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr1_-_143913143 0.49 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr10_+_65281123 0.49 ENST00000298249.4
ENST00000373758.4
REEP3
receptor accessory protein 3
chr12_-_39299406 0.49 ENST00000331366.5
CPNE8
copine VIII
chr1_+_215740709 0.49 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr10_-_48416849 0.49 ENST00000249598.1
GDF2
growth differentiation factor 2
chr15_+_52043758 0.49 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr11_-_67141090 0.48 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr16_+_12070567 0.48 ENST00000566228.1
SNX29
sorting nexin 29
chr10_-_23003460 0.48 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_+_50898881 0.48 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr2_-_99552620 0.47 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr7_+_102553430 0.47 ENST00000339431.4
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr14_+_53196872 0.47 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr20_+_48599506 0.47 ENST00000244050.2
SNAI1
snail family zinc finger 1
chr9_-_6007787 0.47 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
KIAA2026
chr10_+_92980517 0.47 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr6_+_153071925 0.46 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr19_-_6110474 0.46 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr3_-_149688896 0.45 ENST00000239940.7
PFN2
profilin 2
chr1_-_91487013 0.45 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr2_+_33661382 0.45 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_+_24741013 0.45 ENST00000315183.7
ENST00000395799.3
TNRC6A
trinucleotide repeat containing 6A
chr1_-_115212696 0.45 ENST00000393276.3
ENST00000393277.1
DENND2C
DENN/MADD domain containing 2C

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.7 1.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.7 2.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.6 1.8 GO:0033341 regulation of collagen binding(GO:0033341)
0.4 3.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.4 1.2 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4 1.1 GO:0009405 pathogenesis(GO:0009405)
0.4 1.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.3 1.0 GO:2000974 mitral valve formation(GO:0003192) cardiac right atrium morphogenesis(GO:0003213) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 1.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 1.2 GO:0072554 blood vessel lumenization(GO:0072554)
0.3 0.9 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 0.9 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.3 1.6 GO:1903758 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3 1.0 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.3 0.8 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.2 GO:0060067 cervix development(GO:0060067)
0.2 1.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.7 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2 0.7 GO:0007412 axon target recognition(GO:0007412)
0.2 1.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.6 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 0.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 2.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 0.8 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) ganglion morphogenesis(GO:0061552) blood vessel endothelial cell fate specification(GO:0097101) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.9 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 1.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.4 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 1.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.4 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1 0.9 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.4 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.5 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.6 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.7 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.4 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.5 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 0.7 GO:0060214 endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.1 0.3 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 1.0 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.3 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.2 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.9 GO:0035973 aggrephagy(GO:0035973)
0.1 0.2 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.1 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.4 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.7 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.7 GO:0032328 alanine transport(GO:0032328)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.7 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 1.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0001555 oocyte growth(GO:0001555)
0.1 1.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.3 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.2 GO:0045082 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.3 GO:0071878 negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.3 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.2 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.7 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.6 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.1 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.4 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.2 GO:0010958 regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:2000687 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0048319 mesoderm migration involved in gastrulation(GO:0007509) axial mesoderm morphogenesis(GO:0048319)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0051036 regulation of multivesicular body size(GO:0010796) regulation of endosome size(GO:0051036)
0.0 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 1.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 1.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.1 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.2 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.6 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.8 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 1.0 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.6 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 1.2 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 1.2 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.9 GO:0090102 cochlea development(GO:0090102)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 1.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.8 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:2000480 negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.3 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.5 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 0.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 0.9 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.7 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.2 0.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 1.2 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.2 1.9 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.1 0.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.8 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.6 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.9 GO:0097443 sorting endosome(GO:0097443)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 1.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.8 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004103 choline kinase activity(GO:0004103)
0.3 2.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.0 GO:0019961 interferon binding(GO:0019961)
0.3 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 0.8 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 0.8 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 0.7 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.2 0.6 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.2 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 3.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.5 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 1.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0031692 alpha-1B adrenergic receptor binding(GO:0031692)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0052827 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol pentakisphosphate phosphatase activity(GO:0052827) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.7 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 1.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 1.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0000828 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0032050 very-low-density lipoprotein particle receptor activity(GO:0030229) clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 0.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.6 PID EPO PATHWAY EPO signaling pathway
0.0 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 3.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.8 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development