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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HAND1

Z-value: 0.51

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.2 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg19_v2_chr5_-_153857819_153857824-0.291.6e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 1.50 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr4_+_41614720 1.04 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr4_+_41614909 1.03 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr1_+_164528866 0.84 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr3_+_141103634 0.79 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_-_150754935 0.68 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr2_-_208031943 0.60 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_+_201997595 0.49 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_201997492 0.47 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_201997676 0.47 ENST00000462763.1
ENST00000479953.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_112051994 0.41 ENST00000473539.1
ENST00000315711.8
ENST00000383681.3
CD200
CD200 molecule
chr6_+_80341000 0.40 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr1_-_214638146 0.38 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chrX_+_149531524 0.37 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr19_+_12862486 0.37 ENST00000549706.1
BEST2
bestrophin 2
chr19_+_12862604 0.36 ENST00000553030.1
BEST2
bestrophin 2
chr10_+_99344104 0.36 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr6_-_39282329 0.35 ENST00000373231.4
KCNK17
potassium channel, subfamily K, member 17
chr6_+_35996859 0.35 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr14_-_53331239 0.33 ENST00000553663.1
FERMT2
fermitin family member 2
chr6_-_39282221 0.33 ENST00000453413.2
KCNK17
potassium channel, subfamily K, member 17
chr11_+_124932986 0.32 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_124933191 0.32 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_369804 0.32 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr16_-_10652993 0.30 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr11_+_124932955 0.30 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_-_72432950 0.29 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr20_-_56285595 0.25 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr20_-_56286479 0.24 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_-_25475120 0.23 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr6_-_133119668 0.22 ENST00000275227.4
ENST00000538764.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chr14_+_96722539 0.22 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr1_+_207262627 0.20 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr1_+_207262578 0.20 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr21_+_34602200 0.20 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr12_+_98909260 0.19 ENST00000556029.1
TMPO
thymopoietin
chr8_+_79428539 0.19 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr17_-_36358166 0.19 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr22_+_25003568 0.19 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr1_+_207262540 0.18 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr19_+_507299 0.18 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr7_-_141957847 0.17 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr3_-_15382875 0.17 ENST00000408919.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr3_-_9811595 0.17 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chr1_+_207262170 0.16 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr1_-_52870104 0.16 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr21_+_34602377 0.16 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr1_-_52870059 0.15 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr5_+_36608422 0.15 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_90153696 0.14 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr12_-_10955226 0.13 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr22_+_24999114 0.13 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr22_+_25003606 0.13 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr17_+_66624280 0.12 ENST00000585484.1
RP11-118B18.1
RP11-118B18.1
chr6_+_6588902 0.12 ENST00000230568.4
LY86
lymphocyte antigen 86
chr12_-_110271178 0.12 ENST00000261740.2
ENST00000392719.2
ENST00000346520.2
TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr11_-_2323089 0.12 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr11_+_112130988 0.11 ENST00000595053.1
AP002884.2
LOC100132686 protein; Uncharacterized protein
chr6_+_44191507 0.11 ENST00000371724.1
ENST00000371713.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_45478568 0.11 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr7_-_142207004 0.11 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chrX_-_34675391 0.11 ENST00000275954.3
TMEM47
transmembrane protein 47
chr2_+_3642545 0.11 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr16_+_70328680 0.11 ENST00000563206.1
ENST00000451014.3
ENST00000568625.1
DDX19B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
chr11_-_63330842 0.11 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr10_+_82297658 0.11 ENST00000339284.2
SH2D4B
SH2 domain containing 4B
chr12_-_7261772 0.10 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr17_+_43922241 0.10 ENST00000329196.5
SPPL2C
signal peptide peptidase like 2C
chr11_+_67171391 0.10 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr11_+_67171548 0.10 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr19_-_36304201 0.10 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr9_-_115095123 0.10 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr11_+_67171358 0.10 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr1_-_54405773 0.10 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr17_+_45908974 0.09 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr3_+_123813509 0.09 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr19_+_47421933 0.08 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr8_+_1993152 0.08 ENST00000262113.4
MYOM2
myomesin 2
chr12_+_49717019 0.08 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr14_+_96722152 0.08 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr7_-_20256965 0.08 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr19_-_55866061 0.08 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr22_+_25003626 0.08 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr17_-_56358287 0.08 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr16_-_70729496 0.08 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr7_-_140714739 0.07 ENST00000467334.1
ENST00000324787.5
MRPS33
mitochondrial ribosomal protein S33
chr20_+_58296265 0.07 ENST00000395636.2
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr8_+_1993173 0.07 ENST00000523438.1
MYOM2
myomesin 2
chr17_+_6347729 0.07 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr20_-_1165117 0.07 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr3_-_157251383 0.07 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chrX_+_15767971 0.07 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr6_-_87804815 0.07 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr12_-_25801478 0.07 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr7_+_76139833 0.07 ENST00000257632.5
UPK3B
uroplakin 3B
chrX_-_133930285 0.06 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr10_+_103113802 0.06 ENST00000370187.3
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr17_+_6347761 0.06 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr12_-_57630873 0.06 ENST00000556732.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr20_+_3713314 0.06 ENST00000254963.2
ENST00000542646.1
ENST00000399701.1
HSPA12B
heat shock 70kD protein 12B
chr12_+_53848549 0.06 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr10_+_103113840 0.05 ENST00000393441.4
ENST00000408038.2
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr4_-_40632605 0.05 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr10_+_118350468 0.05 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr7_+_140378955 0.05 ENST00000473512.1
ADCK2
aarF domain containing kinase 2
chr7_+_110731062 0.05 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr7_-_140714430 0.05 ENST00000393008.3
MRPS33
mitochondrial ribosomal protein S33
chr9_+_125376948 0.05 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chrX_+_70364667 0.04 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr2_+_210444142 0.04 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr10_+_118350522 0.04 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr6_+_134210243 0.04 ENST00000367882.4
TCF21
transcription factor 21
chr17_+_11924129 0.03 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr2_+_204732487 0.03 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr20_+_123010 0.03 ENST00000382398.3
DEFB126
defensin, beta 126
chr2_+_231860830 0.03 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr14_-_65409438 0.03 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr19_+_36359341 0.03 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr2_+_98262497 0.03 ENST00000258424.2
COX5B
cytochrome c oxidase subunit Vb
chr14_+_24422795 0.03 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr1_-_32210275 0.03 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr17_-_64216748 0.02 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_231860596 0.02 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr4_-_25161996 0.02 ENST00000513285.1
ENST00000382103.2
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr17_-_43025005 0.02 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr17_-_61781750 0.02 ENST00000582026.1
STRADA
STE20-related kinase adaptor alpha
chr12_+_68042517 0.02 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr12_+_53848505 0.01 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr19_-_13044494 0.01 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr1_-_52344471 0.01 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr12_-_68647281 0.01 ENST00000328087.4
ENST00000538666.1
IL22
interleukin 22
chr14_-_74892805 0.01 ENST00000331628.3
ENST00000554953.1
SYNDIG1L
synapse differentiation inducing 1-like
chr2_-_42588338 0.01 ENST00000234301.2
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr14_-_65409502 0.01 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr11_-_2323290 0.00 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr12_+_67663056 0.00 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr14_+_74083548 0.00 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr10_-_104211294 0.00 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 1.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:2000340 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0018095 sperm axoneme assembly(GO:0007288) protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.4 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.3 GO:0035838 growing cell tip(GO:0035838)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.9 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling