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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HBP1

Z-value: 0.95

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
HBP1
ENSG00000105856.9 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg19_v2_chr7_+_106809406_106809460-0.793.1e-06Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_127455200 3.59 ENST00000398101.3
MGLL
monoglyceride lipase
chr3_+_72937182 2.98 ENST00000389617.4
GXYLT2
glucoside xylosyltransferase 2
chr6_-_44233361 2.77 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr12_-_89919965 2.77 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr7_-_92777606 2.66 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr2_-_220264703 2.33 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr4_+_86525299 2.00 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr12_-_89920030 1.92 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr19_-_6690723 1.91 ENST00000601008.1
C3
complement component 3
chr1_+_65613340 1.88 ENST00000546702.1
AK4
adenylate kinase 4
chr11_+_73087309 1.79 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr1_+_145209092 1.77 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr5_+_125758813 1.71 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr1_-_47082495 1.68 ENST00000545730.1
ENST00000531769.1
ENST00000319928.3
MKNK1
MOB3C
MAP kinase interacting serine/threonine kinase 1
MOB kinase activator 3C
chr10_+_24528108 1.61 ENST00000438429.1
KIAA1217
KIAA1217
chr11_+_20044096 1.60 ENST00000533917.1
NAV2
neuron navigator 2
chr3_+_111805182 1.55 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52
chromosome 3 open reading frame 52
chr7_-_2354099 1.55 ENST00000222990.3
SNX8
sorting nexin 8
chr7_+_18535786 1.55 ENST00000406072.1
HDAC9
histone deacetylase 9
chr2_+_74425689 1.43 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr15_+_75074410 1.43 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_+_65216462 1.41 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_4853442 1.40 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chrX_+_18725758 1.35 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr22_+_30477000 1.31 ENST00000403975.1
HORMAD2
HORMA domain containing 2
chr10_+_82300575 1.31 ENST00000313455.4
SH2D4B
SH2 domain containing 4B
chr1_+_65613217 1.30 ENST00000545314.1
AK4
adenylate kinase 4
chr19_-_18508396 1.27 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr20_+_45523227 1.24 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr10_+_111765562 1.22 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr12_-_89919765 1.20 ENST00000541909.1
ENST00000313546.3
POC1B
POC1 centriolar protein B
chr11_-_65667884 1.20 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr15_+_75074385 1.20 ENST00000220003.9
CSK
c-src tyrosine kinase
chr1_+_111773349 1.18 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr2_+_219433588 1.13 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr10_-_60027642 1.12 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr2_-_239197201 1.06 ENST00000254658.3
PER2
period circadian clock 2
chr6_+_149539767 1.05 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr17_-_39165366 1.04 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr11_-_65667997 1.03 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr22_-_18256742 1.01 ENST00000317361.7
BID
BH3 interacting domain death agonist
chr19_+_39390320 0.96 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr4_+_100495864 0.96 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr6_-_35992270 0.95 ENST00000394602.2
ENST00000355574.2
SLC26A8
solute carrier family 26 (anion exchanger), member 8
chr3_-_145878954 0.94 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_+_31805131 0.94 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr8_-_8751068 0.91 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr17_-_48207157 0.91 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr20_-_48330377 0.90 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr12_+_21654714 0.87 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr3_+_100428268 0.86 ENST00000240851.4
TFG
TRK-fused gene
chr11_+_94277017 0.86 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr4_-_119757322 0.83 ENST00000379735.5
SEC24D
SEC24 family member D
chr19_+_17830051 0.82 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr3_+_100428316 0.81 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG
TRK-fused gene
chr2_-_197226875 0.80 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_-_119757239 0.79 ENST00000280551.6
SEC24D
SEC24 family member D
chr7_+_29874341 0.78 ENST00000409290.1
ENST00000242140.5
WIPF3
WAS/WASL interacting protein family, member 3
chr15_-_66649010 0.77 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr4_-_47983519 0.77 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr12_-_99548270 0.74 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_-_42143963 0.74 ENST00000585388.1
ENST00000293406.3
LSM12
LSM12 homolog (S. cerevisiae)
chr3_+_100428188 0.72 ENST00000418917.2
ENST00000490574.1
TFG
TRK-fused gene
chr21_+_45138941 0.72 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr7_-_75443118 0.72 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr2_-_239197238 0.71 ENST00000254657.3
PER2
period circadian clock 2
chr7_-_105319536 0.68 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr6_+_30614779 0.68 ENST00000293604.6
ENST00000376473.5
C6orf136
chromosome 6 open reading frame 136
chr2_-_224702257 0.67 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr17_-_41856305 0.66 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr17_+_56270084 0.66 ENST00000225371.5
EPX
eosinophil peroxidase
chr19_+_39390587 0.65 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr5_+_156887027 0.65 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr1_+_44435646 0.64 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2
DPH2 homolog (S. cerevisiae)
chr3_+_140770183 0.64 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr16_-_745946 0.64 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr20_+_25176318 0.62 ENST00000354989.5
ENST00000360031.2
ENST00000376652.4
ENST00000439162.1
ENST00000433417.1
ENST00000417467.1
ENST00000433259.2
ENST00000427553.1
ENST00000435520.1
ENST00000418890.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr3_-_52090461 0.62 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr19_+_34855925 0.61 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr1_+_85527987 0.61 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr19_+_34855874 0.61 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chrX_-_135333514 0.61 ENST00000370661.1
ENST00000370660.3
MAP7D3
MAP7 domain containing 3
chr11_+_67183557 0.60 ENST00000445895.2
CARNS1
carnosine synthase 1
chr4_+_159236462 0.60 ENST00000460056.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr8_+_63161491 0.59 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chrX_+_152599604 0.58 ENST00000370251.3
ENST00000421401.3
ZNF275
zinc finger protein 275
chr16_+_11762270 0.57 ENST00000329565.5
SNN
stannin
chr19_+_34856141 0.57 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr11_+_43702322 0.55 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr21_+_34602200 0.55 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr11_+_69061594 0.54 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr3_+_5163905 0.54 ENST00000256496.3
ENST00000419534.2
ARL8B
ADP-ribosylation factor-like 8B
chr2_+_208576259 0.53 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chrX_+_150151824 0.53 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr10_-_134756030 0.53 ENST00000368586.5
ENST00000368582.2
TTC40
tetratricopeptide repeat domain 40
chr2_-_224702201 0.51 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr21_+_34602377 0.51 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr7_+_117120017 0.50 ENST00000003084.6
ENST00000454343.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr7_-_150721570 0.50 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr17_-_42327236 0.50 ENST00000399246.2
AC003102.1
AC003102.1
chr19_+_49055332 0.49 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr12_-_58146128 0.49 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr15_+_57884117 0.49 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr6_+_135818979 0.48 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271
long intergenic non-protein coding RNA 271
chr16_+_31366536 0.48 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_+_30614886 0.48 ENST00000376471.4
C6orf136
chromosome 6 open reading frame 136
chr6_+_29555683 0.47 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr6_-_30640811 0.47 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr19_+_19144384 0.46 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr9_-_128246769 0.46 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr17_+_40950900 0.46 ENST00000588527.1
CNTD1
cyclin N-terminal domain containing 1
chr14_+_102430855 0.46 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr11_+_57435219 0.46 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr2_+_208576355 0.45 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1
cyclin Y-like 1
chr17_-_36904437 0.45 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr1_+_12976450 0.45 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr20_-_23967432 0.45 ENST00000286890.4
ENST00000278765.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr6_-_9933500 0.44 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr7_+_65540853 0.44 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr4_+_26322409 0.44 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_231902193 0.44 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr19_-_3500635 0.44 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr19_+_18794470 0.44 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr15_+_57884086 0.44 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr8_-_11725549 0.44 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB
cathepsin B
chr2_-_30144432 0.43 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr11_-_89653576 0.41 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr7_+_65540780 0.41 ENST00000304874.9
ASL
argininosuccinate lyase
chr5_-_16465901 0.41 ENST00000308683.2
ZNF622
zinc finger protein 622
chr11_-_47574664 0.40 ENST00000310513.5
ENST00000531165.1
CELF1
CUGBP, Elav-like family member 1
chr9_-_25678856 0.39 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr1_-_53163992 0.39 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr10_-_120101752 0.39 ENST00000369170.4
FAM204A
family with sequence similarity 204, member A
chr7_-_135612198 0.38 ENST00000589735.1
LUZP6
leucine zipper protein 6
chr16_-_3661578 0.37 ENST00000294008.3
SLX4
SLX4 structure-specific endonuclease subunit
chr22_-_22337154 0.37 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr5_+_140762268 0.36 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr19_+_3506261 0.36 ENST00000441788.2
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr20_-_33872548 0.36 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr4_+_26322185 0.35 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_140071011 0.35 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr1_-_154155595 0.34 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3
tropomyosin 3
chr3_-_197025447 0.34 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr1_+_13736907 0.34 ENST00000316412.5
PRAMEF20
PRAME family member 20
chr2_-_207629997 0.33 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr5_+_150040403 0.33 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr3_+_184032313 0.33 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_66725837 0.32 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chrX_-_23926004 0.32 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr5_-_140070897 0.31 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr15_+_57884199 0.31 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GCOM1
MYZAP
POLR2M
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr3_+_184032419 0.31 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr2_+_12246664 0.31 ENST00000449986.1
AC096559.1
AC096559.1
chr15_+_34261089 0.30 ENST00000383263.5
CHRM5
cholinergic receptor, muscarinic 5
chr22_-_50708781 0.29 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr6_-_133035185 0.29 ENST00000367928.4
VNN1
vanin 1
chrX_+_108779004 0.28 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr20_-_33872518 0.28 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr19_-_6333614 0.28 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr2_-_207630033 0.28 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr1_-_12946025 0.28 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr3_+_184032283 0.27 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr22_-_30956746 0.27 ENST00000437282.1
ENST00000447224.1
ENST00000427899.1
ENST00000406955.1
ENST00000452827.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_-_161056802 0.27 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr6_+_42531798 0.26 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr2_-_69180083 0.26 ENST00000328895.4
GKN2
gastrokine 2
chr13_-_20077417 0.25 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr12_-_100378006 0.25 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_56092187 0.25 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579
chr3_-_197026152 0.25 ENST00000419354.1
DLG1
discs, large homolog 1 (Drosophila)
chr12_-_93835665 0.25 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr22_+_20105259 0.25 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr20_-_1373682 0.25 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr8_+_23104130 0.25 ENST00000313219.7
ENST00000519984.1
CHMP7
charged multivesicular body protein 7
chr19_-_45657028 0.25 ENST00000429338.1
ENST00000589776.1
NKPD1
NTPase, KAP family P-loop domain containing 1
chrX_+_23925918 0.25 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr11_-_3818688 0.25 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr1_-_154155675 0.25 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr17_+_8152590 0.25 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
PFAS
phosphoribosylformylglycinamidine synthase
chr10_-_73976884 0.24 ENST00000317126.4
ENST00000545550.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr7_-_5821314 0.24 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr8_-_116504448 0.24 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr4_-_46126093 0.24 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr14_-_94759595 0.24 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_-_186288097 0.24 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr1_+_13516066 0.23 ENST00000332192.6
PRAMEF21
PRAME family member 21
chr12_-_93836028 0.23 ENST00000318066.2
UBE2N
ubiquitin-conjugating enzyme E2N
chr7_-_149158187 0.22 ENST00000247930.4
ZNF777
zinc finger protein 777
chr6_+_10521574 0.22 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_+_96038476 0.21 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
CAST
calpastatin
chr2_+_207630081 0.21 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr14_-_94759408 0.21 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr20_+_44486246 0.21 ENST00000255152.2
ENST00000454862.2
ZSWIM3
zinc finger, SWIM-type containing 3
chr3_+_159943362 0.21 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr17_+_6918093 0.21 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr11_+_5410607 0.20 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr4_+_153457404 0.20 ENST00000604157.1
ENST00000594836.1
MIR4453
microRNA 4453
chr19_-_38714847 0.20 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr22_+_24236191 0.20 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr19_+_4198072 0.20 ENST00000262970.5
ANKRD24
ankyrin repeat domain 24

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6 1.8 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.5 3.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 2.2 GO:0007296 vitellogenesis(GO:0007296)
0.4 1.8 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.3 2.6 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.3 3.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.3 0.9 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.3 2.8 GO:0042940 D-amino acid transport(GO:0042940)
0.3 0.8 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 0.7 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.4 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.2 0.7 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.7 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.2 2.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.6 GO:0021564 vagus nerve development(GO:0021564)
0.2 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.8 GO:0002215 defense response to nematode(GO:0002215)
0.2 1.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.2 0.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.7 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 1.0 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.8 GO:0048478 replication fork protection(GO:0048478)
0.1 0.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 1.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 1.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 1.0 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 5.8 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.9 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.2 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0010446 response to alkaline pH(GO:0010446)
0.1 2.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.6 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.4 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0051684 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 1.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:2000400 pantothenate metabolic process(GO:0015939) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.4 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 1.2 GO:0001895 retina homeostasis(GO:0001895)
0.0 1.0 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.8 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.5 GO:0007618 mating(GO:0007618)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 2.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 1.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 3.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 2.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.6 1.8 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.5 3.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.5 1.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 0.9 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 1.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.7 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.2 1.4 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.2 0.7 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.7 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.2 1.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.2 1.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 3.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 2.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.2 GO:0004568 chitinase activity(GO:0004568)
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.8 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0030332 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) cyclin binding(GO:0030332)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0043394 proteoglycan binding(GO:0043394)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 1.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 3.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction