Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for HES1

Z-value: 0.93

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.682.0e-04Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_89182178 3.65 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 3.60 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 3.16 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr2_-_225907150 2.63 ENST00000258390.7
dedicator of cytokinesis 10
chr3_-_127541679 2.48 ENST00000265052.5
monoglyceride lipase
chr11_-_60719213 2.18 ENST00000227880.3
solute carrier family 15 (oligopeptide transporter), member 3
chr1_-_9189229 2.01 ENST00000377411.4
G protein-coupled receptor 157
chr7_+_73703728 2.01 ENST00000361545.5
ENST00000223398.6
CAP-GLY domain containing linker protein 2
chr16_+_2039946 1.85 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr1_+_23037323 1.80 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPH receptor B2
chr7_-_47621736 1.74 ENST00000311160.9
tensin 3
chr2_+_150187020 1.70 ENST00000334166.4
LY6/PLAUR domain containing 6
chr22_-_50963976 1.68 ENST00000252785.3
ENST00000395693.3
SCO2 cytochrome c oxidase assembly protein
chr3_-_127542021 1.67 ENST00000434178.2
monoglyceride lipase
chr3_-_127542051 1.65 ENST00000398104.1
monoglyceride lipase
chr22_-_50964558 1.40 ENST00000535425.1
ENST00000439934.1
SCO2 cytochrome c oxidase assembly protein
chr6_-_143266297 1.39 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr16_-_72127456 1.35 ENST00000562153.1
thioredoxin-like 4B
chr1_-_205290865 1.35 ENST00000367157.3
NUAK family, SNF1-like kinase, 2
chr21_+_34697209 1.29 ENST00000270139.3
interferon (alpha, beta and omega) receptor 1
chr10_-_105615164 1.21 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr7_-_558876 1.20 ENST00000354513.5
ENST00000402802.3
platelet-derived growth factor alpha polypeptide
chr1_+_165797024 1.18 ENST00000372212.4
uridine-cytidine kinase 2
chr8_-_142011036 1.16 ENST00000520892.1
protein tyrosine kinase 2
chr2_+_102759199 1.11 ENST00000409288.1
ENST00000410023.1
interleukin 1 receptor, type I
chr6_-_154831779 1.08 ENST00000607772.1
CNKSR family member 3
chr2_-_25142708 1.06 ENST00000260600.5
ENST00000435135.1
adenylate cyclase 3
chr21_+_45285050 1.05 ENST00000291572.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_151038785 1.04 ENST00000413040.2
ENST00000568733.1
negative regulator of ubiquitin-like proteins 1
chr22_-_50964849 1.02 ENST00000543927.1
ENST00000423348.1
SCO2 cytochrome c oxidase assembly protein
chr17_-_1394940 1.01 ENST00000570984.2
ENST00000361007.2
myosin IC
chr8_+_145064233 1.01 ENST00000529301.1
ENST00000395068.4
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr22_-_31503490 1.00 ENST00000400299.2
Selenoprotein M
chr20_+_6748311 0.98 ENST00000378827.4
bone morphogenetic protein 2
chr8_+_145064215 0.96 ENST00000313269.5
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_+_42724423 0.96 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr11_-_67981295 0.96 ENST00000405515.1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr22_+_29279552 0.96 ENST00000544604.2
zinc and ring finger 3
chr2_-_10588630 0.95 ENST00000234111.4
ornithine decarboxylase 1
chr6_+_44095347 0.94 ENST00000323267.6
transmembrane protein 63B
chr3_+_133292851 0.93 ENST00000503932.1
CDV3 homolog (mouse)
chr8_+_104384616 0.93 ENST00000520337.1
collagen triple helix repeat containing 1
chr16_-_54963026 0.91 ENST00000560208.1
ENST00000557792.1
colorectal neoplasia differentially expressed (non-protein coding)
chr10_+_103892787 0.91 ENST00000278070.2
ENST00000413464.2
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr6_-_43543702 0.90 ENST00000265351.7
exportin 5
chr1_-_111743285 0.89 ENST00000357640.4
DENN/MADD domain containing 2D
chr10_+_90750493 0.89 ENST00000357339.2
ENST00000355279.2
Fas cell surface death receptor
chr4_+_1873155 0.88 ENST00000507820.1
ENST00000514045.1
Wolf-Hirschhorn syndrome candidate 1
chr17_+_74381343 0.86 ENST00000392496.3
sphingosine kinase 1
chr3_+_133292574 0.86 ENST00000264993.3
CDV3 homolog (mouse)
chr7_-_131241361 0.85 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr6_+_37787704 0.85 ENST00000474522.1
zinc finger, AN1-type domain 3
chr10_+_90750378 0.85 ENST00000355740.2
ENST00000352159.4
Fas cell surface death receptor
chr8_-_141645645 0.83 ENST00000519980.1
ENST00000220592.5
argonaute RISC catalytic component 2
chr19_+_14544099 0.82 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr14_+_93799556 0.81 ENST00000256339.4
unc-79 homolog (C. elegans)
chr21_-_44495919 0.79 ENST00000398158.1
cystathionine-beta-synthase
chr2_-_136743169 0.78 ENST00000264161.4
aspartyl-tRNA synthetase
chr1_+_41445413 0.78 ENST00000541520.1
CTP synthase 1
chr17_-_48207157 0.78 ENST00000330175.4
ENST00000503131.1
sterile alpha motif domain containing 14
chr17_-_28257080 0.77 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr5_+_156693091 0.77 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr2_+_219433588 0.76 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr17_+_46985731 0.76 ENST00000360943.5
ubiquitin-conjugating enzyme E2Z
chr2_-_136743039 0.76 ENST00000537273.1
aspartyl-tRNA synthetase
chr19_+_33072373 0.76 ENST00000586035.1
programmed cell death 5
chr11_+_65029421 0.75 ENST00000541089.1
polymerase (DNA directed), alpha 2, accessory subunit
chr20_+_61273797 0.74 ENST00000217159.1
solute carrier organic anion transporter family, member 4A1
chr8_+_32406179 0.74 ENST00000405005.3
neuregulin 1
chr20_+_55966444 0.72 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chr15_-_58357932 0.70 ENST00000347587.3
aldehyde dehydrogenase 1 family, member A2
chr3_-_47823298 0.69 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr17_+_7348658 0.69 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr11_-_9286921 0.68 ENST00000328194.3
DENN/MADD domain containing 5A
chr17_-_79849438 0.68 ENST00000331204.4
ENST00000505490.2
Aly/REF export factor
chr5_+_156693159 0.68 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr22_+_38302285 0.68 ENST00000215957.6
MICAL-like 1
chr16_-_72127550 0.67 ENST00000268483.3
thioredoxin-like 4B
chrX_-_9734004 0.67 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr17_+_7348374 0.67 ENST00000306071.2
ENST00000572857.1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr15_-_58357866 0.67 ENST00000537372.1
aldehyde dehydrogenase 1 family, member A2
chr9_+_33025209 0.65 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr12_-_89919965 0.65 ENST00000548729.1
POC1B-GALNT4 readthrough
chr1_+_44445549 0.65 ENST00000356836.6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr19_+_49622646 0.65 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr19_+_984313 0.65 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WD repeat domain 18
chr10_-_62493223 0.64 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr16_-_54962625 0.64 ENST00000559432.1
colorectal neoplasia differentially expressed (non-protein coding)
chr19_+_33071974 0.63 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
programmed cell death 5
chr1_-_167522982 0.63 ENST00000370509.4
cellular repressor of E1A-stimulated genes 1
chr6_+_31588478 0.63 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr1_+_44444865 0.62 ENST00000372324.1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr16_-_4466622 0.62 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr1_-_6662919 0.62 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr8_+_141521386 0.61 ENST00000220913.5
ENST00000519533.1
chromatin accessibility complex 1
chr8_-_145515055 0.60 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
block of proliferation 1
chr7_+_100303676 0.59 ENST00000303151.4
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr12_+_7023491 0.59 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr10_+_81107271 0.59 ENST00000448165.1
peptidylprolyl isomerase F
chr1_-_231004220 0.59 ENST00000366663.5
chromosome 1 open reading frame 198
chr6_+_44094627 0.59 ENST00000259746.9
transmembrane protein 63B
chr7_-_139477500 0.58 ENST00000406875.3
ENST00000428878.2
homeodomain interacting protein kinase 2
chr17_+_7255208 0.58 ENST00000333751.3
potassium channel tetramerization domain containing 11
chr3_+_9773409 0.58 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
bromodomain and PHD finger containing, 1
chr16_-_54962704 0.57 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
colorectal neoplasia differentially expressed (non-protein coding)
chr3_-_179754806 0.57 ENST00000485199.1
peroxisomal biogenesis factor 5-like
chr13_-_102068706 0.57 ENST00000251127.6
sodium leak channel, non-selective
chr8_+_31496809 0.56 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr3_+_133292759 0.56 ENST00000431519.2
CDV3 homolog (mouse)
chr21_-_40685536 0.55 ENST00000341322.4
bromodomain and WD repeat domain containing 1
chr2_+_178077477 0.55 ENST00000411529.2
ENST00000435711.1
heterogeneous nuclear ribonucleoprotein A3
chr17_+_45726803 0.55 ENST00000535458.2
ENST00000583648.1
karyopherin (importin) beta 1
chr15_+_52311398 0.55 ENST00000261845.5
mitogen-activated protein kinase 6
chr9_-_140484917 0.55 ENST00000298585.2
zinc finger, MYND-type containing 19
chr11_+_94277017 0.54 ENST00000358752.2
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr1_-_38273840 0.54 ENST00000373044.2
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr12_+_107349497 0.54 ENST00000548125.1
ENST00000280756.4
chromosome 12 open reading frame 23
chr10_-_90751038 0.54 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr19_-_1863567 0.53 ENST00000250916.4
Kruppel-like factor 16
chr11_-_46142615 0.53 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr21_-_18985230 0.53 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr10_-_121302195 0.53 ENST00000369103.2
regulator of G-protein signaling 10
chr17_-_74722536 0.53 ENST00000585429.1
jumonji domain containing 6
chr2_+_201390843 0.53 ENST00000357799.4
ENST00000409203.3
shugoshin-like 2 (S. pombe)
chr16_-_54962415 0.53 ENST00000501177.3
ENST00000559598.2
colorectal neoplasia differentially expressed (non-protein coding)
chr20_-_43280325 0.52 ENST00000537820.1
adenosine deaminase
chr19_+_489140 0.52 ENST00000587541.1
mucosal vascular addressin cell adhesion molecule 1
chr21_+_45138941 0.52 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr12_-_109251345 0.51 ENST00000360239.3
ENST00000326495.5
ENST00000551165.1
slingshot protein phosphatase 1
chr6_+_43543864 0.51 ENST00000372236.4
ENST00000535400.1
polymerase (DNA directed), eta
chr1_-_23670817 0.51 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr17_-_78450398 0.51 ENST00000306773.4
neuronal pentraxin I
chr2_+_106361333 0.50 ENST00000233154.4
ENST00000451463.2
NCK adaptor protein 2
chr12_-_106641728 0.50 ENST00000378026.4
cytoskeleton-associated protein 4
chr11_-_65430251 0.50 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr2_+_192543153 0.49 ENST00000425611.2
nucleic acid binding protein 1
chr17_+_79650962 0.49 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_+_94577074 0.49 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr12_+_77158021 0.49 ENST00000550876.1
zinc finger, DHHC-type containing 17
chr2_+_192542850 0.49 ENST00000410026.2
nucleic acid binding protein 1
chr17_+_36861735 0.48 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr19_+_10982336 0.48 ENST00000344150.4
coactivator-associated arginine methyltransferase 1
chr7_-_80548667 0.48 ENST00000265361.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr17_+_28256874 0.48 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr6_+_31126291 0.48 ENST00000376257.3
ENST00000376255.4
transcription factor 19
chr12_+_7023735 0.48 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr11_-_615570 0.47 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr10_-_99094458 0.47 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_43424500 0.47 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
solute carrier family 2 (facilitated glucose transporter), member 1
chr14_-_53162361 0.47 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr7_-_92463210 0.47 ENST00000265734.4
cyclin-dependent kinase 6
chr6_-_13814663 0.47 ENST00000359495.2
ENST00000379170.4
mitochondrial calcium uniporter regulator 1
chr16_-_4466565 0.46 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16 readthrough
coronin 7
chr3_+_127348005 0.46 ENST00000342480.6
podocalyxin-like 2
chr14_-_77279153 0.46 ENST00000251089.2
angel homolog 1 (Drosophila)
chr2_-_224702257 0.46 ENST00000409375.1
adaptor-related protein complex 1, sigma 3 subunit
chr12_-_89920030 0.45 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr14_+_103243813 0.45 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TNF receptor-associated factor 3
chr7_-_130353553 0.45 ENST00000330992.7
ENST00000445977.2
coatomer protein complex, subunit gamma 2
chr13_+_76123883 0.45 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr2_-_120124258 0.44 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
chromosome 2 open reading frame 76
chr12_+_26111823 0.44 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr9_+_92219919 0.44 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr2_-_135476552 0.44 ENST00000281924.6
transmembrane protein 163
chr1_+_41707996 0.44 ENST00000425554.1
RP11-399E6.1
chr19_-_38397285 0.44 ENST00000303868.5
WD repeat domain 87
chrX_+_153770421 0.44 ENST00000369609.5
ENST00000369607.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr17_-_73257667 0.44 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
chr3_-_179754556 0.43 ENST00000263962.8
peroxisomal biogenesis factor 5-like
chr8_-_72756667 0.43 ENST00000325509.4
musculin
chr19_+_10982189 0.43 ENST00000327064.4
ENST00000588947.1
coactivator-associated arginine methyltransferase 1
chr21_+_45527171 0.43 ENST00000291576.7
ENST00000456705.1
PWP2 periodic tryptophan protein homolog (yeast)
chr5_+_151151504 0.43 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr16_-_4401258 0.42 ENST00000577031.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr16_-_4401284 0.42 ENST00000318059.3
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr22_-_45636650 0.42 ENST00000336156.5
KIAA0930
chr8_+_38614807 0.42 ENST00000330691.6
ENST00000348567.4
transforming, acidic coiled-coil containing protein 1
chr7_-_140340576 0.42 ENST00000275884.6
ENST00000475837.1
DENN/MADD domain containing 2A
chr5_+_6633534 0.42 ENST00000537411.1
ENST00000538824.1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr3_+_130613226 0.41 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATPase, Ca++ transporting, type 2C, member 1
chr5_+_151151471 0.41 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_30185971 0.41 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr1_-_23670752 0.41 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr14_-_67982146 0.40 ENST00000557779.1
ENST00000557006.1
transmembrane protein 229B
chr21_-_43373999 0.40 ENST00000380486.3
C2 calcium-dependent domain containing 2
chr14_-_95236551 0.40 ENST00000238558.3
goosecoid homeobox
chr2_-_120124383 0.40 ENST00000334816.7
chromosome 2 open reading frame 76
chr7_-_2354099 0.40 ENST00000222990.3
sorting nexin 8
chr6_-_43197189 0.40 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr1_-_19283163 0.39 ENST00000455833.2
intermediate filament family orphan 2
chr2_-_224702201 0.39 ENST00000446015.2
adaptor-related protein complex 1, sigma 3 subunit
chr16_-_87417351 0.39 ENST00000311635.7
F-box protein 31
chr22_-_39151463 0.39 ENST00000405510.1
ENST00000433561.1
Sad1 and UNC84 domain containing 2
chr3_-_170744498 0.39 ENST00000382808.4
ENST00000314251.3
solute carrier family 2 (facilitated glucose transporter), member 2
chr5_-_6633397 0.39 ENST00000264670.6
ENST00000539938.1
NOP2/Sun RNA methyltransferase family, member 2
chr1_+_28844778 0.38 ENST00000411533.1
regulator of chromosome condensation 1
chr10_-_79397391 0.38 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr22_+_45559722 0.38 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
nucleoporin 50kDa
chr8_+_1922024 0.38 ENST00000320248.3
kelch repeat and BTB (POZ) domain containing 11
chr4_-_926161 0.38 ENST00000511163.1
cyclin G associated kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 5.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.5 1.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.4 1.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.4 1.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4 1.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.4 1.1 GO:0008355 olfactory learning(GO:0008355)
0.3 1.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 1.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 0.9 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.3 1.2 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 1.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 0.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 0.8 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.3 0.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 0.8 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 1.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 1.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.9 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 0.4 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.2 0.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.8 GO:0046102 inosine metabolic process(GO:0046102)
0.2 1.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.2 1.8 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.2 0.6 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 4.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.2 2.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.5 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.5 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 0.5 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 1.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.7 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.2 0.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.2 0.6 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.4 GO:0035799 ureter maturation(GO:0035799)
0.1 0.4 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 1.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.4 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 2.0 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.9 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.5 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.5 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) mammary gland specification(GO:0060594) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.5 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.4 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:1905068 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.6 GO:0060992 response to fungicide(GO:0060992)
0.1 1.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.5 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0044111 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) development involved in symbiotic interaction(GO:0044111)
0.1 0.5 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.1 0.7 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.3 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.5 GO:0045007 depurination(GO:0045007)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 2.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.2 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.4 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 1.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.3 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.4 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.4 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.5 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.8 GO:0032780 protein import into mitochondrial matrix(GO:0030150) negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.9 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 1.7 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.6 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.0 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.5 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0071499 cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 2.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:2000619 regulation of histone H4-K16 acetylation(GO:2000618) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.8 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 1.0 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.0 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0045820 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.0 GO:0038001 paracrine signaling(GO:0038001) corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.4 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.0 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 2.1 GO:0015992 proton transport(GO:0015992)
0.0 3.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.3 1.0 GO:0045160 myosin I complex(GO:0045160)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 0.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 0.5 GO:0071159 NF-kappaB complex(GO:0071159)
0.2 0.5 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 0.6 GO:1990742 microvesicle(GO:1990742)
0.2 0.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 11.1 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 2.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.7 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0044326 chromaffin granule membrane(GO:0042584) dendritic spine neck(GO:0044326)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 3.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 2.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.0 GO:0030016 myofibril(GO:0030016)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 5.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.2 GO:0035578 azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 1.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 2.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.5 1.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 1.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.4 4.1 GO:0004645 phosphorylase activity(GO:0004645)
0.4 1.1 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.4 1.1 GO:0019961 interferon binding(GO:0019961)
0.3 1.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 5.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.3 GO:0004461 lactose synthase activity(GO:0004461)
0.3 1.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.3 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 0.8 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.3 1.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 0.8 GO:0098808 mRNA cap binding(GO:0098808)
0.3 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.2 0.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 0.5 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 0.5 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.2 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.7 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.9 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.5 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.6 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.9 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 0.3 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 0.3 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.2 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.5 GO:0035240 dopamine binding(GO:0035240)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 3.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 12.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 3.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription