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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HES7_HES5

Z-value: 0.69

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Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
ENSG00000179111.4 hes family bHLH transcription factor 7
ENSG00000197921.5 hes family bHLH transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES5hg19_v2_chr1_-_2461684_2461710-0.481.5e-02Click!
HES7hg19_v2_chr17_-_8027402_8027432-0.311.4e-01Click!

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39851094 4.32 ENST00000302541.6
myosin VIIA and Rab interacting protein
chr14_+_65879437 2.40 ENST00000394585.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr13_+_35516390 1.76 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr14_+_65879668 1.76 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_+_95066823 1.67 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr17_-_62084241 1.51 ENST00000449662.2
intercellular adhesion molecule 2
chr17_+_48172639 1.37 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr3_-_69062764 1.27 ENST00000295571.5
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_125820348 1.21 ENST00000509064.1
ENST00000508835.1
solute carrier family 41, member 3
chr1_+_16083154 1.19 ENST00000375771.1
filamin binding LIM protein 1
chr19_-_3700388 1.12 ENST00000589578.1
ENST00000537021.1
ENST00000539785.1
ENST00000335312.3
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr19_-_55458860 1.07 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLR family, pyrin domain containing 7
chr5_+_78532003 1.06 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr20_-_36793663 1.00 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr19_-_19049791 0.98 ENST00000594439.1
ENST00000221222.11
homer homolog 3 (Drosophila)
chr17_+_30813576 0.96 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr4_-_18023350 0.95 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr6_-_30712313 0.94 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chr21_-_33985127 0.87 ENST00000290155.3
chromosome 21 open reading frame 59
chr20_-_2821271 0.86 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr22_+_24891210 0.85 ENST00000382760.2
ureidopropionase, beta
chr20_+_306221 0.81 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr20_-_36793774 0.81 ENST00000361475.2
transglutaminase 2
chr19_+_13106383 0.80 ENST00000397661.2
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_131265443 0.74 ENST00000306010.7
O-6-methylguanine-DNA methyltransferase
chr2_-_86116093 0.73 ENST00000377332.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_-_63376013 0.70 ENST00000540943.1
phospholipase A2, group XVI
chr3_+_49027308 0.67 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr20_-_45985464 0.66 ENST00000458360.2
ENST00000262975.4
zinc finger, MYND-type containing 8
chr20_-_45985414 0.64 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
zinc finger, MYND-type containing 8
chr9_-_139658965 0.63 ENST00000316144.5
lipocalin 15
chr1_-_231114542 0.60 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
tetratricopeptide repeat domain 13
chr11_+_9595180 0.55 ENST00000450114.2
WEE1 G2 checkpoint kinase
chr13_+_115047097 0.55 ENST00000351487.5
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr14_+_65878565 0.54 ENST00000556518.1
ENST00000557164.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr17_-_61523535 0.53 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr17_-_18266660 0.50 ENST00000582653.1
ENST00000352886.6
serine hydroxymethyltransferase 1 (soluble)
chr1_+_28832455 0.49 ENST00000398958.2
ENST00000427469.1
ENST00000434290.1
ENST00000373833.6
regulator of chromosome condensation 1
chr17_-_61523622 0.49 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr10_+_22605304 0.46 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1 readthrough
COMM domain containing 3
chr13_+_80055581 0.45 ENST00000487865.1
Nedd4 family interacting protein 2
chr2_+_201980961 0.45 ENST00000342795.5
CASP8 and FADD-like apoptosis regulator
chr4_-_144826682 0.44 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr11_-_116968987 0.44 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr10_+_22605374 0.43 ENST00000448361.1
COMM domain containing 3
chr11_-_119066545 0.42 ENST00000415318.1
coiled-coil domain containing 153
chr1_-_45140227 0.42 ENST00000372237.3
transmembrane protein 53
chr13_+_80055284 0.41 ENST00000218652.7
Nedd4 family interacting protein 2
chr1_-_45140074 0.40 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
transmembrane protein 53
chr10_+_180405 0.40 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
zinc finger, MYND-type containing 11
chr4_+_1003742 0.39 ENST00000398484.2
fibroblast growth factor receptor-like 1
chr20_+_35201993 0.38 ENST00000373872.4
TGFB-induced factor homeobox 2
chr1_-_26233423 0.38 ENST00000357865.2
stathmin 1
chr4_-_6202247 0.37 ENST00000409021.3
ENST00000409371.3
janus kinase and microtubule interacting protein 1
chrX_-_16887963 0.37 ENST00000380084.4
retinoblastoma binding protein 7
chr14_-_77737543 0.37 ENST00000298352.4
neuroglobin
chr3_-_151102529 0.37 ENST00000302632.3
purinergic receptor P2Y, G-protein coupled, 12
chr20_+_306177 0.37 ENST00000544632.1
SRY (sex determining region Y)-box 12
chr7_+_101460882 0.37 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1
chr12_+_112204691 0.35 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr15_-_57025759 0.34 ENST00000267807.7
zinc finger protein 280D
chr20_+_35201857 0.34 ENST00000373874.2
TGFB-induced factor homeobox 2
chr14_-_106967788 0.34 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr1_+_231114795 0.34 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1 homolog (S. cerevisiae)
chr11_+_45944190 0.32 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
glycosyltransferase-like 1B
chr12_+_27175476 0.32 ENST00000546323.1
ENST00000282892.3
mediator complex subunit 21
chr17_+_5185552 0.31 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
rabaptin, RAB GTPase binding effector protein 1
chr19_+_50691437 0.31 ENST00000598205.1
myosin, heavy chain 14, non-muscle
chr8_+_142402089 0.31 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr1_+_210111534 0.31 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
synaptotagmin XIV
chr7_+_23636992 0.31 ENST00000307471.3
ENST00000409765.1
coiled-coil domain containing 126
chr1_-_26232951 0.30 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr17_-_42907564 0.30 ENST00000592524.1
gap junction protein, gamma 1, 45kDa
chr16_-_21416640 0.30 ENST00000542817.1
nuclear pore complex interacting protein family, member B3
chr16_-_21849091 0.30 ENST00000537951.1
nuclear pore complex interacting protein family, member B4
chr2_+_201981119 0.30 ENST00000395148.2
CASP8 and FADD-like apoptosis regulator
chr17_-_18950950 0.29 ENST00000284154.5
GRB2-related adaptor protein
chr4_+_113152978 0.29 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr3_-_25824925 0.28 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
N-glycanase 1
chr13_+_27998681 0.28 ENST00000381140.4
general transcription factor IIIA
chr17_+_46048376 0.28 ENST00000338399.4
CDK5 regulatory subunit associated protein 3
chr4_-_76439483 0.28 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_-_3523507 0.28 ENST00000327435.6
acireductone dioxygenase 1
chr16_-_57513657 0.27 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
docking protein 4
chr9_+_92219919 0.26 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr2_+_201980827 0.25 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr12_-_91348949 0.25 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr7_+_99933730 0.24 ENST00000610247.1
paired immunoglobin-like type 2 receptor beta
chr4_+_113152881 0.24 ENST00000274000.5
adaptor-related protein complex 1 associated regulatory protein
chr16_+_770975 0.24 ENST00000569529.1
ENST00000564000.1
ENST00000219535.3
family with sequence similarity 173, member A
chr2_+_27665289 0.24 ENST00000407293.1
keratinocyte associated protein 3
chr17_-_5015129 0.24 ENST00000575898.1
ENST00000416429.2
zinc finger protein 232
chr2_-_105372203 0.23 ENST00000424321.1
long intergenic non-protein coding RNA 1114
chr7_+_23637118 0.23 ENST00000448353.1
coiled-coil domain containing 126
chr7_-_27205136 0.23 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr5_+_159895275 0.22 ENST00000517927.1
microRNA 146a
chr6_-_143771799 0.21 ENST00000237283.8
adenosine deaminase, tRNA-specific 2
chr6_+_46620676 0.21 ENST00000371347.5
ENST00000411689.2
solute carrier family 25, member 27
chr2_+_25264933 0.20 ENST00000401432.3
ENST00000403714.3
EFR3 homolog B (S. cerevisiae)
chr22_-_31741757 0.20 ENST00000215919.3
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_57656570 0.20 ENST00000269834.1
zinc finger, imprinted 3
chr16_-_5115913 0.19 ENST00000474471.3
chromosome 16 open reading frame 89
chr17_-_17109579 0.19 ENST00000321560.3
phospholipase D family, member 6
chr10_-_71169031 0.19 ENST00000373307.1
tachykinin receptor 2
chr2_-_198299726 0.19 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr1_-_109655377 0.19 ENST00000369948.3
chromosome 1 open reading frame 194
chr16_-_30237150 0.18 ENST00000543463.1
Putative NPIP-like protein LOC613037
chr17_-_35969409 0.18 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr8_+_38089198 0.18 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr18_-_46987000 0.18 ENST00000442713.2
ENST00000269445.6
dymeclin
chr9_-_100395756 0.18 ENST00000341170.4
ENST00000354801.2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr4_-_76439596 0.18 ENST00000451788.1
ENST00000512706.1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_+_113403434 0.17 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr19_-_52511334 0.16 ENST00000602063.1
ENST00000597747.1
ENST00000594083.1
ENST00000593650.1
ENST00000599631.1
ENST00000598071.1
ENST00000601178.1
ENST00000376716.5
ENST00000391795.3
zinc finger protein 615
chr7_-_130598059 0.16 ENST00000432045.2
microRNA 29a
chr4_-_6692246 0.16 ENST00000499502.2
RP11-539L10.2
chr4_-_144940477 0.16 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr2_+_74648848 0.16 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr1_+_28261492 0.15 ENST00000373894.3
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_150254936 0.15 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chrX_-_153523462 0.15 ENST00000361930.3
ENST00000369926.1
testis expressed 28
chr17_-_41465674 0.13 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
long intergenic non-protein coding RNA 910
chr16_-_48419361 0.13 ENST00000394725.2
siah E3 ubiquitin protein ligase 1
chr12_-_49318715 0.13 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr6_+_122931366 0.13 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_-_17783135 0.13 ENST00000265018.3
family with sequence similarity 184, member B
chr16_-_81129845 0.13 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr12_-_104350898 0.12 ENST00000552940.1
ENST00000547975.1
ENST00000549478.1
ENST00000546540.1
ENST00000546819.1
ENST00000378090.4
ENST00000547945.1
chromosome 12 open reading frame 73
chr17_-_40346477 0.11 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GH3 domain containing
chr1_+_28261621 0.11 ENST00000549094.1
sphingomyelin phosphodiesterase, acid-like 3B
chrX_-_152736013 0.11 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chr2_-_220108309 0.10 ENST00000409640.1
galactosidase, beta 1-like
chr4_+_2819883 0.10 ENST00000511747.1
ENST00000503393.2
SH3-domain binding protein 2
chr9_+_100395891 0.10 ENST00000375147.3
nuclear cap binding protein subunit 1, 80kDa
chr19_+_37837185 0.10 ENST00000541583.2
HKR1, GLI-Kruppel zinc finger family member
chr12_+_31226779 0.10 ENST00000542838.1
ENST00000407793.2
ENST00000251758.5
ENST00000228264.6
ENST00000438391.2
ENST00000415475.2
ENST00000545668.1
ENST00000350437.4
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr22_+_41777927 0.09 ENST00000266304.4
thyrotrophic embryonic factor
chr5_+_152870287 0.09 ENST00000340592.5
glutamate receptor, ionotropic, AMPA 1
chr2_-_169769787 0.08 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr22_+_37415700 0.08 ENST00000397129.1
mercaptopyruvate sulfurtransferase
chr22_+_37415676 0.08 ENST00000401419.3
mercaptopyruvate sulfurtransferase
chr2_-_220118631 0.08 ENST00000248437.4
tubulin, alpha 4a
chr4_-_184580304 0.08 ENST00000510968.1
ENST00000512740.1
ENST00000327570.9
RWD domain containing 4
chr11_+_64059464 0.07 ENST00000394525.2
potassium channel, subfamily K, member 4
chr22_+_37415728 0.07 ENST00000404802.3
mercaptopyruvate sulfurtransferase
chr19_+_45281118 0.07 ENST00000270279.3
ENST00000341505.4
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr10_+_49514698 0.07 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr11_-_6440624 0.07 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr1_+_166958504 0.07 ENST00000447624.1
maelstrom spermatogenic transposon silencer
chr4_+_184580420 0.06 ENST00000334690.6
ENST00000357207.4
trafficking protein particle complex 11
chr6_-_112194484 0.06 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN oncogene related to SRC, FGR, YES
chr2_+_27665232 0.06 ENST00000543753.1
ENST00000288873.3
keratinocyte associated protein 3
chr16_+_29127282 0.06 ENST00000562902.1
RP11-426C22.5
chr14_+_24641062 0.06 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8 meiotic recombination protein
chrY_-_26194116 0.06 ENST00000306882.4
ENST00000382407.1
chromodomain protein, Y-linked, 1B
chr19_-_36054555 0.05 ENST00000262623.3
ATPase, H+/K+ exchanging, alpha polypeptide
chr22_+_22681656 0.05 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chrX_+_134124968 0.05 ENST00000330288.4
small integral membrane protein 10
chr1_+_210111570 0.05 ENST00000367019.1
ENST00000472886.1
synaptotagmin XIV
chr4_-_184580353 0.04 ENST00000326397.5
RWD domain containing 4
chr7_+_99202003 0.04 ENST00000609449.1
GS1-259H13.2
chr2_+_202655184 0.04 ENST00000410091.3
cyclin-dependent kinase 15
chr9_+_103204553 0.04 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr15_-_43212836 0.04 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
tau tubulin kinase 2
chr1_+_166958497 0.04 ENST00000367870.2
maelstrom spermatogenic transposon silencer
chr1_-_26232522 0.04 ENST00000399728.1
stathmin 1
chr15_-_29561979 0.03 ENST00000332303.4
necdin-like 2
chr4_+_128886532 0.03 ENST00000444616.1
ENST00000388795.5
chromosome 4 open reading frame 29
chr16_+_3550924 0.03 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
clusterin associated protein 1
chrY_+_27768264 0.03 ENST00000361963.2
ENST00000306609.4
chromodomain protein, Y-linked, 1
chr1_+_44457261 0.03 ENST00000372318.3
coiled-coil domain containing 24
chr16_-_23160591 0.03 ENST00000219689.7
ubiquitin specific peptidase 31
chr11_-_777467 0.03 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
Parkinson disease 7 domain containing 1
chr8_-_65711310 0.03 ENST00000310193.3
cytochrome P450, family 7, subfamily B, polypeptide 1
chr19_-_55954230 0.03 ENST00000376325.4
shisa family member 7
chr21_-_47575481 0.02 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
formimidoyltransferase cyclodeaminase
chr3_-_149510553 0.02 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr19_-_4723761 0.02 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
dipeptidyl-peptidase 9
chr17_-_47492164 0.02 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr5_-_143550241 0.02 ENST00000522203.1
Yip1 domain family, member 5
chr8_+_17780483 0.02 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
pericentriolar material 1
chr1_-_201476274 0.01 ENST00000340006.2
cysteine and glycine-rich protein 1
chr16_+_333152 0.01 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
protein disulfide isomerase family A, member 2
chr18_+_9913977 0.01 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr2_+_61372226 0.01 ENST00000426997.1
chromosome 2 open reading frame 74
chr12_+_133066137 0.01 ENST00000434748.2
fibrosin-like 1
chr9_+_706842 0.01 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr2_+_201170596 0.01 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr8_+_104033296 0.01 ENST00000521514.1
ENST00000518738.1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chrX_+_153524024 0.00 ENST00000369915.3
ENST00000217905.7
transketolase-like 1
chrX_-_16888448 0.00 ENST00000468092.1
ENST00000404022.1
ENST00000380087.2
retinoblastoma binding protein 7

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.6 1.8 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.0 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 4.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 1.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 0.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 0.5 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.9 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.7 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 1.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 4.3 GO:0031045 dense core granule(GO:0031045)
0.1 2.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 4.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.6 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 1.3 GO:0045178 basal part of cell(GO:0045178)
0.0 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 1.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.3 1.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 1.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.5 GO:0070905 serine binding(GO:0070905)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 4.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.7 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines