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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HINFP

Z-value: 0.64

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Transcription factors associated with HINFP

Gene Symbol Gene ID Gene Info
ENSG00000172273.8 histone H4 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HINFPhg19_v2_chr11_+_118992269_1189923340.321.2e-01Click!

Activity profile of HINFP motif

Sorted Z-values of HINFP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_149363662 2.15 ENST00000355292.3
ENST00000358102.3
nuclear receptor subfamily 3, group C, member 2
chr10_-_131762105 1.89 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr1_+_109102652 1.44 ENST00000370035.3
ENST00000405454.1
family with sequence similarity 102, member B
chr22_-_28197486 1.34 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr10_+_94608218 1.33 ENST00000371543.1
exocyst complex component 6
chr1_+_61547405 1.23 ENST00000371189.4
nuclear factor I/A
chr4_-_186733363 1.23 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr3_+_110790590 1.14 ENST00000485303.1
poliovirus receptor-related 3
chr1_+_61547894 1.14 ENST00000403491.3
nuclear factor I/A
chr6_+_24495185 1.02 ENST00000348925.2
aldehyde dehydrogenase 5 family, member A1
chr4_-_18023350 1.00 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr13_-_77460525 0.95 ENST00000377474.2
ENST00000317765.2
potassium channel tetramerization domain containing 12
chr19_-_49843539 0.90 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
chr1_+_212458834 0.86 ENST00000261461.2
protein phosphatase 2, regulatory subunit B', alpha
chr1_-_92351769 0.85 ENST00000212355.4
transforming growth factor, beta receptor III
chr17_-_46690839 0.85 ENST00000498634.2
homeobox B8
chr6_+_35310312 0.84 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
peroxisome proliferator-activated receptor delta
chr10_+_99079008 0.77 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr6_-_144329531 0.71 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr4_+_123747834 0.71 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr3_-_129612394 0.67 ENST00000505616.1
ENST00000426664.2
transmembrane and coiled-coil domain family 1
chr6_+_35310391 0.67 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
peroxisome proliferator-activated receptor delta
chr7_+_94023873 0.66 ENST00000297268.6
collagen, type I, alpha 2
chr12_+_53773944 0.65 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr6_-_111804905 0.64 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_-_43453734 0.63 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr10_+_94608245 0.59 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr19_+_1249869 0.59 ENST00000591446.2
midnolin
chr9_-_98279241 0.58 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
patched 1
chr1_+_6845578 0.58 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr18_+_268148 0.57 ENST00000581677.1
RP11-705O1.8
chr12_-_90102594 0.57 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_46766577 0.52 ENST00000256689.5
solute carrier family 38, member 2
chr4_-_492891 0.52 ENST00000338977.5
ENST00000511833.2
zinc finger protein 721
chr4_+_166128735 0.50 ENST00000226725.6
kelch-like family member 2
chr1_+_212208919 0.49 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr10_-_131909071 0.49 ENST00000456581.1
long intergenic non-protein coding RNA 959
chr13_-_41240717 0.48 ENST00000379561.5
forkhead box O1
chr9_+_139921916 0.48 ENST00000314330.2
chromosome 9 open reading frame 139
chrX_-_119695279 0.47 ENST00000336592.6
cullin 4B
chr4_+_123747979 0.46 ENST00000608478.1
fibroblast growth factor 2 (basic)
chr4_-_107237374 0.46 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBC1 domain containing kinase
chr1_+_22351977 0.45 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr4_-_107237340 0.45 ENST00000394706.3
TBC1 domain containing kinase
chr12_-_2113583 0.45 ENST00000397173.4
ENST00000280665.6
decapping mRNA 1B
chr1_+_6845497 0.44 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr11_-_73309228 0.43 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr6_+_24495067 0.43 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr19_-_36545649 0.43 ENST00000292894.1
THAP domain containing 8
chr8_+_6565854 0.43 ENST00000285518.6
1-acylglycerol-3-phosphate O-acyltransferase 5
chr1_-_36916011 0.43 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
organic solute carrier partner 1
chr1_-_22109682 0.41 ENST00000400301.1
ENST00000532737.1
ubiquitin specific peptidase 48
chr1_+_93913713 0.40 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr13_-_22178284 0.36 ENST00000468222.2
ENST00000382374.4
mitochondrial calcium uptake 2
chr6_-_139695757 0.35 ENST00000367651.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr7_-_17980091 0.35 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
sorting nexin 13
chr11_+_62104897 0.34 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
asparaginase like 1
chr6_+_56820018 0.34 ENST00000370746.3
BEN domain containing 6
chr11_-_62380199 0.33 ENST00000419857.1
ENST00000394773.2
echinoderm microtubule associated protein like 3
chr6_+_56819773 0.33 ENST00000370750.2
BEN domain containing 6
chr11_+_66045634 0.33 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr1_-_22109484 0.33 ENST00000529637.1
ubiquitin specific peptidase 48
chr1_-_153919128 0.33 ENST00000361217.4
DENN/MADD domain containing 4B
chr3_-_38691119 0.33 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
sodium channel, voltage-gated, type V, alpha subunit
chrX_+_154299690 0.32 ENST00000340647.4
ENST00000330045.7
BRCA1/BRCA2-containing complex, subunit 3
chrX_+_154299753 0.32 ENST00000369459.2
ENST00000369462.1
ENST00000411985.1
ENST00000399042.1
BRCA1/BRCA2-containing complex, subunit 3
chr3_+_49209023 0.32 ENST00000332780.2
kelch domain containing 8B
chr9_+_37120536 0.31 ENST00000336755.5
ENST00000534928.1
ENST00000322831.6
zinc finger, CCHC domain containing 7
chr6_-_24721054 0.31 ENST00000378119.4
chromosome 6 open reading frame 62
chr1_-_16563641 0.31 ENST00000375599.3
REM2 and RAB-like small GTPase 1
chr17_-_6616678 0.31 ENST00000381074.4
ENST00000293800.6
ENST00000572352.1
ENST00000576323.1
ENST00000573648.1
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr3_-_196295437 0.30 ENST00000429115.1
WD repeat domain 53
chr11_+_3876859 0.30 ENST00000300737.4
stromal interaction molecule 1
chr10_-_62761188 0.29 ENST00000357917.4
Rho-related BTB domain containing 1
chr17_-_66453562 0.29 ENST00000262139.5
ENST00000546360.1
WD repeat domain, phosphoinositide interacting 1
chr11_-_2162162 0.29 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr20_-_30458491 0.29 ENST00000339738.5
dual specificity phosphatase 15
chr11_-_2162468 0.28 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr4_-_111119804 0.28 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr5_+_61602055 0.28 ENST00000381103.2
kinesin heavy chain member 2A
chr14_+_64971292 0.27 ENST00000358738.3
ENST00000394712.2
zinc finger and BTB domain containing 1
chr12_+_90102729 0.27 ENST00000605386.1
long intergenic non-protein coding RNA 936
chr12_+_12510045 0.27 ENST00000314565.4
loss of heterozygosity, 12, chromosomal region 1
chr20_-_30458019 0.27 ENST00000486996.1
ENST00000398084.2
dual specificity phosphatase 15
chr11_+_66059339 0.27 ENST00000327259.4
transmembrane protein 151A
chr11_+_64879317 0.26 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
transmembrane 7 superfamily member 2
chr13_+_48877895 0.26 ENST00000267163.4
retinoblastoma 1
chr2_+_204193129 0.26 ENST00000417864.1
abl-interactor 2
chr10_-_104179682 0.26 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr1_-_36916066 0.25 ENST00000315643.9
organic solute carrier partner 1
chr1_-_94703118 0.25 ENST00000260526.6
ENST00000370217.3
Rho GTPase activating protein 29
chr1_-_212208842 0.25 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
integrator complex subunit 7
chr11_+_28131821 0.25 ENST00000379199.2
ENST00000303459.6
methyltransferase like 15
chr3_-_49377499 0.24 ENST00000265560.4
ubiquitin specific peptidase 4 (proto-oncogene)
chr17_-_73178599 0.24 ENST00000578238.1
small ubiquitin-like modifier 2
chr19_+_917287 0.24 ENST00000592648.1
ENST00000234371.5
KISS1 receptor
chr3_-_13009168 0.23 ENST00000273221.4
IQ motif and Sec7 domain 1
chr12_+_70637494 0.23 ENST00000548159.1
ENST00000549750.1
ENST00000551043.1
CCR4-NOT transcription complex, subunit 2
chr12_+_51985001 0.23 ENST00000354534.6
sodium channel, voltage gated, type VIII, alpha subunit
chr17_+_17206635 0.23 ENST00000389022.4
5',3'-nucleotidase, mitochondrial
chr16_+_14726672 0.23 ENST00000261658.2
ENST00000563971.1
bifunctional apoptosis regulator
chr17_+_38024417 0.22 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
zona pellucida binding protein 2
chr1_-_169455169 0.22 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr1_-_114355083 0.22 ENST00000261441.5
round spermatid basic protein 1
chr1_+_107599267 0.21 ENST00000361318.5
ENST00000370078.1
protein arginine methyltransferase 6
chr17_-_16395455 0.21 ENST00000409083.3
family with sequence similarity 211, member A
chr9_-_123555655 0.21 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
F-box and WD repeat domain containing 2
chr12_+_56521840 0.21 ENST00000394048.5
extended synaptotagmin-like protein 1
chr2_+_204193149 0.20 ENST00000422511.2
abl-interactor 2
chr19_+_14017116 0.20 ENST00000589606.1
coiled-coil and C2 domain containing 1A
chr22_+_18593507 0.20 ENST00000330423.3
tubulin, alpha 8
chr8_+_26240414 0.20 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr4_+_91048706 0.20 ENST00000509176.1
coiled-coil serine-rich protein 1
chr19_+_34972543 0.20 ENST00000590071.2
Wilms tumor 1 interacting protein
chr3_+_32433154 0.20 ENST00000334983.5
ENST00000349718.4
CKLF-like MARVEL transmembrane domain containing 7
chr14_-_92572894 0.19 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr14_-_64971288 0.19 ENST00000394715.1
zinc finger and BTB domain containing 25
chr3_-_48936272 0.19 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr17_+_30593195 0.19 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
rhomboid, veinlet-like 3 (Drosophila)
chr11_-_66336060 0.18 ENST00000310325.5
cathepsin F
chr4_+_154387480 0.18 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
chr4_-_77997126 0.17 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
cyclin I
chr17_-_73179046 0.17 ENST00000314523.7
ENST00000420826.2
small ubiquitin-like modifier 2
chr3_+_183853052 0.17 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr19_+_14017003 0.17 ENST00000318003.7
coiled-coil and C2 domain containing 1A
chr12_+_69633317 0.17 ENST00000435070.2
cleavage and polyadenylation specific factor 6, 68kDa
chr21_+_35445827 0.17 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr3_-_28390120 0.16 ENST00000334100.6
5-azacytidine induced 2
chr16_+_81069433 0.16 ENST00000299575.4
ATM interactor
chr12_+_52400719 0.16 ENST00000293662.4
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr11_-_68039364 0.16 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
chromosome 11 open reading frame 24
chr2_+_30670077 0.16 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
lysocardiolipin acyltransferase 1
chr6_+_26104104 0.16 ENST00000377803.2
histone cluster 1, H4c
chr3_+_32433363 0.16 ENST00000465248.1
CKLF-like MARVEL transmembrane domain containing 7
chr7_-_26240357 0.16 ENST00000354667.4
ENST00000356674.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr6_-_35464817 0.16 ENST00000338863.7
TEA domain family member 3
chr2_-_97523721 0.16 ENST00000393537.4
ankyrin repeat domain 39
chr3_-_49377446 0.15 ENST00000351842.4
ENST00000416417.1
ENST00000415188.1
ubiquitin specific peptidase 4 (proto-oncogene)
chr16_-_70557430 0.15 ENST00000393612.4
ENST00000564653.1
ENST00000323786.5
component of oligomeric golgi complex 4
chr5_+_43121698 0.15 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
zinc finger protein 131
chr2_-_54087066 0.15 ENST00000394705.2
ENST00000352846.3
ENST00000406625.2
G protein-coupled receptor 75
GPR75-ASB3 readthrough
Ankyrin repeat and SOCS box protein 3
chr12_+_7282795 0.15 ENST00000266546.6
calsyntenin 3
chr2_+_120770581 0.15 ENST00000263713.5
erythrocyte membrane protein band 4.1 like 5
chr8_-_102217796 0.14 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
zinc finger protein 706
chr9_-_139922726 0.14 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr16_-_30006922 0.14 ENST00000564026.1
HIRA interacting protein 3
chr22_+_29168652 0.14 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr9_-_139922631 0.14 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_185014496 0.14 ENST00000367510.3
ring finger protein 2
chr17_+_11501816 0.14 ENST00000454412.2
dynein, axonemal, heavy chain 9
chr5_-_127873496 0.13 ENST00000508989.1
fibrillin 2
chr20_-_30458432 0.13 ENST00000375966.4
ENST00000278979.3
dual specificity phosphatase 15
chr8_-_66754172 0.13 ENST00000401827.3
phosphodiesterase 7A
chr3_+_152552685 0.13 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr16_+_56225248 0.13 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr9_+_96214166 0.13 ENST00000375389.3
ENST00000333936.5
ENST00000340893.4
family with sequence similarity 120A
chr18_+_54814288 0.13 ENST00000585477.1
biorientation of chromosomes in cell division 1-like 2
chr8_-_27462822 0.12 ENST00000522098.1
clusterin
chr15_-_75932528 0.12 ENST00000403490.1
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr17_+_11501748 0.12 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr2_-_37384175 0.12 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
eukaryotic translation initiation factor 2-alpha kinase 2
chr5_+_56469939 0.12 ENST00000506184.2
GC-rich promoter binding protein 1
chr6_-_33267101 0.12 ENST00000497454.1
ral guanine nucleotide dissociation stimulator-like 2
chr20_-_35492048 0.12 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr8_-_144241432 0.12 ENST00000430474.2
lymphocyte antigen 6 complex, locus H
chr3_+_196295482 0.12 ENST00000440469.1
ENST00000311630.6
F-box protein 45
chr17_+_48450575 0.12 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr2_+_64068074 0.11 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UDP-glucose pyrophosphorylase 2
chr8_-_144241664 0.11 ENST00000342752.4
lymphocyte antigen 6 complex, locus H
chr19_+_6372444 0.11 ENST00000245812.3
alkB, alkylation repair homolog 7 (E. coli)
chr3_+_63897605 0.11 ENST00000487717.1
ataxin 7
chr19_-_14117074 0.11 ENST00000588885.1
ENST00000254325.4
regulatory factor X, 1 (influences HLA class II expression)
chr2_-_233352531 0.11 ENST00000304546.1
endothelin converting enzyme-like 1
chr6_-_35464727 0.11 ENST00000402886.3
TEA domain family member 3
chr17_-_1420182 0.11 ENST00000421807.2
inositol polyphosphate-5-phosphatase K
chr11_+_64073699 0.10 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr19_-_45004556 0.10 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
zinc finger protein 180
chr19_-_39881777 0.10 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_-_6440624 0.10 ENST00000311051.3
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr13_-_31040060 0.10 ENST00000326004.4
ENST00000341423.5
high mobility group box 1
chr1_-_1510204 0.09 ENST00000291386.3
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
chr5_+_56469843 0.09 ENST00000514387.2
GC-rich promoter binding protein 1
chr12_+_56137064 0.09 ENST00000257868.5
ENST00000546799.1
growth differentiation factor 11
chr6_+_56819895 0.09 ENST00000370748.3
BEN domain containing 6
chr5_-_154317740 0.09 ENST00000285873.7
gem (nuclear organelle) associated protein 5
chr1_-_197115818 0.09 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr10_+_124907638 0.09 ENST00000339992.3
H6 family homeobox 2
chr8_-_100905925 0.09 ENST00000518171.1
cytochrome c oxidase subunit VIc
chr5_+_65440032 0.09 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr11_-_6440283 0.09 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr1_+_29063119 0.08 ENST00000474884.1
ENST00000542507.1
YTH domain family, member 2
chr1_+_214454492 0.08 ENST00000366957.5
ENST00000415093.2
SET and MYND domain containing 2
chrX_-_154299501 0.08 ENST00000369476.3
ENST00000369484.3
mature T-cell proliferation 1
C-x(9)-C motif containing 4
chr19_+_45754505 0.08 ENST00000262891.4
ENST00000300843.4
MAP/microtubule affinity-regulating kinase 4
chr5_-_132166579 0.08 ENST00000378679.3
shroom family member 1
chr11_-_6633799 0.08 ENST00000299424.4
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr21_+_35445811 0.07 ENST00000399312.2
mitochondrial ribosomal protein S6
chr6_+_30312908 0.07 ENST00000433076.2
ENST00000442966.2
ENST00000428040.2
ENST00000436442.2
ribonuclease P/MRP 21kDa subunit
chr6_-_89673280 0.07 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNA guanylyltransferase and 5'-phosphatase
chr20_+_57267669 0.07 ENST00000356091.6
aminopeptidase-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0009450 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 0.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.2 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 1.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.6 GO:0010157 response to chlorate(GO:0010157)
0.1 0.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 1.5 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.5 GO:1902617 response to fluoride(GO:1902617)
0.1 0.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.3 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.6 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.3 GO:0071930 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 2.4 GO:0072189 ureter development(GO:0072189)
0.1 0.6 GO:0071386 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.6 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.5 GO:0032328 alanine transport(GO:0032328)
0.1 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 1.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.8 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:2001151 negative regulation of glycogen (starch) synthase activity(GO:2000466) regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156) metanephric proximal tubule development(GO:0072237)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 1.0 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 1.5 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 1.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 3.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs