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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HINFP1

Z-value: 0.35

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity profile of HINFP1 motif

Sorted Z-values of HINFP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_55033815 0.97 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr3_+_133292851 0.64 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr3_+_133292759 0.61 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr3_+_133293278 0.57 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chrX_-_119249819 0.57 ENST00000217999.2
RHOXF1
Rhox homeobox family, member 1
chr15_+_85525205 0.48 ENST00000394553.1
ENST00000339708.5
PDE8A
phosphodiesterase 8A
chr7_+_6144514 0.45 ENST00000306177.5
ENST00000465073.2
USP42
ubiquitin specific peptidase 42
chr16_+_57279248 0.42 ENST00000562023.1
ENST00000563234.1
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr14_+_73704201 0.42 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr19_+_1524072 0.36 ENST00000454744.2
PLK5
polo-like kinase 5
chr15_-_58357932 0.35 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr18_+_12308231 0.35 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
TUBB6
tubulin, beta 6 class V
chr15_-_58357866 0.34 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr20_-_3996165 0.33 ENST00000545616.2
ENST00000358395.6
RNF24
ring finger protein 24
chr10_-_50970322 0.28 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr10_-_50970382 0.28 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr18_+_12308046 0.26 ENST00000317702.5
TUBB6
tubulin, beta 6 class V
chr9_-_94186131 0.23 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr11_-_61658853 0.22 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr20_+_35974532 0.22 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr19_+_33685490 0.22 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr14_+_45366518 0.20 ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chr11_-_61659006 0.18 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr11_+_637246 0.17 ENST00000176183.5
DRD4
dopamine receptor D4
chr13_-_22033392 0.17 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr2_+_58655461 0.15 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr11_+_57435219 0.14 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr17_-_79481666 0.10 ENST00000575659.1
ACTG1
actin, gamma 1
chr10_-_977564 0.09 ENST00000406525.2
LARP4B
La ribonucleoprotein domain family, member 4B
chr10_+_49514698 0.09 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr10_-_97453650 0.05 ENST00000371209.5
ENST00000371217.5
ENST00000430368.2
TCTN3
tectonic family member 3
chr19_-_5680499 0.05 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr1_-_62785054 0.04 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr1_-_43232649 0.04 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr9_-_86595503 0.03 ENST00000376281.4
ENST00000376264.2
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr1_+_222886694 0.03 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr7_-_1609591 0.03 ENST00000288607.2
ENST00000404674.3
PSMG3
proteasome (prosome, macropain) assembly chaperone 3
chr2_+_130939827 0.01 ENST00000409255.1
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr6_-_144416737 0.00 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr2_-_130939115 0.00 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
SMPD4
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr1_+_43232913 0.00 ENST00000372525.5
ENST00000536543.1
C1orf50
chromosome 1 open reading frame 50

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0035799 ureter maturation(GO:0035799)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.4 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.5 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions