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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for HIVEP1
Z-value: 1.78
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Transcription factors associated with HIVEP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HIVEP1
|
ENSG00000095951.12 | HIVEP zinc finger 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HIVEP1 | hg19_v2_chr6_+_12012536_12012571 | 0.53 | 6.0e-03 | Click! |
Activity profile of HIVEP1 motif
Sorted Z-values of HIVEP1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_76944621 | 12.02 |
ENST00000306602.1
|
CXCL10
|
chemokine (C-X-C motif) ligand 10 |
| chr4_+_74702214 | 11.17 |
ENST00000226317.5
ENST00000515050.1 |
CXCL6
|
chemokine (C-X-C motif) ligand 6 |
| chr19_+_4229495 | 8.77 |
ENST00000221847.5
|
EBI3
|
Epstein-Barr virus induced 3 |
| chr5_-_150460914 | 8.55 |
ENST00000389378.2
|
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr1_-_8000872 | 8.15 |
ENST00000377507.3
|
TNFRSF9
|
tumor necrosis factor receptor superfamily, member 9 |
| chr17_+_40440481 | 8.05 |
ENST00000590726.2
ENST00000452307.2 ENST00000444283.1 ENST00000588868.1 |
STAT5A
|
signal transducer and activator of transcription 5A |
| chr9_-_123691047 | 7.53 |
ENST00000373887.3
|
TRAF1
|
TNF receptor-associated factor 1 |
| chr19_+_45504688 | 7.39 |
ENST00000221452.8
ENST00000540120.1 ENST00000505236.1 |
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B |
| chr1_-_209824643 | 6.70 |
ENST00000391911.1
ENST00000415782.1 |
LAMB3
|
laminin, beta 3 |
| chr17_-_53499310 | 6.37 |
ENST00000262065.3
|
MMD
|
monocyte to macrophage differentiation-associated |
| chr1_+_212738676 | 6.24 |
ENST00000366981.4
ENST00000366987.2 |
ATF3
|
activating transcription factor 3 |
| chr11_+_19798964 | 6.14 |
ENST00000527559.2
|
NAV2
|
neuron navigator 2 |
| chr4_-_74864386 | 5.82 |
ENST00000296027.4
|
CXCL5
|
chemokine (C-X-C motif) ligand 5 |
| chr7_-_22396533 | 5.74 |
ENST00000344041.6
|
RAPGEF5
|
Rap guanine nucleotide exchange factor (GEF) 5 |
| chr11_+_19799327 | 5.69 |
ENST00000540292.1
|
NAV2
|
neuron navigator 2 |
| chr14_+_103589789 | 5.55 |
ENST00000558056.1
ENST00000560869.1 |
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2 |
| chr5_-_150460539 | 5.53 |
ENST00000520931.1
ENST00000520695.1 ENST00000521591.1 ENST00000518977.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr11_-_72492903 | 5.27 |
ENST00000537947.1
|
STARD10
|
StAR-related lipid transfer (START) domain containing 10 |
| chr7_-_22259845 | 5.17 |
ENST00000420196.1
|
RAPGEF5
|
Rap guanine nucleotide exchange factor (GEF) 5 |
| chr9_-_136344197 | 4.93 |
ENST00000414172.1
ENST00000371897.4 |
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6 |
| chr9_-_32526184 | 4.62 |
ENST00000545044.1
ENST00000379868.1 |
DDX58
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| chr12_-_57504069 | 4.59 |
ENST00000543873.2
ENST00000554663.1 ENST00000557635.1 |
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr16_-_11681316 | 4.43 |
ENST00000571688.1
|
LITAF
|
lipopolysaccharide-induced TNF factor |
| chr6_+_31554826 | 4.30 |
ENST00000376089.2
ENST00000396112.2 |
LST1
|
leukocyte specific transcript 1 |
| chr1_+_110453109 | 4.28 |
ENST00000525659.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr14_+_55033815 | 4.14 |
ENST00000554335.1
|
SAMD4A
|
sterile alpha motif domain containing 4A |
| chr6_+_31554779 | 3.98 |
ENST00000376090.2
|
LST1
|
leukocyte specific transcript 1 |
| chr17_+_77021702 | 3.90 |
ENST00000392445.2
ENST00000354124.3 |
C1QTNF1
|
C1q and tumor necrosis factor related protein 1 |
| chr1_+_110453203 | 3.72 |
ENST00000357302.4
ENST00000344188.5 ENST00000329608.6 |
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr6_+_31554962 | 3.70 |
ENST00000376092.3
ENST00000376086.3 ENST00000303757.8 ENST00000376093.2 ENST00000376102.3 |
LST1
|
leukocyte specific transcript 1 |
| chr2_+_161993465 | 3.60 |
ENST00000457476.1
|
TANK
|
TRAF family member-associated NFKB activator |
| chr4_+_139936905 | 3.38 |
ENST00000280614.2
|
CCRN4L
|
CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| chr6_-_31324943 | 3.36 |
ENST00000412585.2
ENST00000434333.1 |
HLA-B
|
major histocompatibility complex, class I, B |
| chr2_-_204400113 | 3.36 |
ENST00000319170.5
|
RAPH1
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
| chr16_+_50730910 | 3.34 |
ENST00000300589.2
|
NOD2
|
nucleotide-binding oligomerization domain containing 2 |
| chr12_-_9913489 | 3.31 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr6_+_138188551 | 3.19 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr11_-_72492878 | 3.18 |
ENST00000535054.1
ENST00000545082.1 |
STARD10
|
StAR-related lipid transfer (START) domain containing 10 |
| chr6_-_31239846 | 3.16 |
ENST00000415537.1
ENST00000376228.5 ENST00000383329.3 |
HLA-C
|
major histocompatibility complex, class I, C |
| chr9_-_130477912 | 3.06 |
ENST00000543175.1
|
PTRH1
|
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) |
| chr6_+_29691198 | 3.02 |
ENST00000440587.2
ENST00000434407.2 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr16_+_53738053 | 2.93 |
ENST00000394647.3
|
FTO
|
fat mass and obesity associated |
| chr14_+_55034599 | 2.81 |
ENST00000392067.3
ENST00000357634.3 |
SAMD4A
|
sterile alpha motif domain containing 4A |
| chr2_-_163175133 | 2.78 |
ENST00000421365.2
ENST00000263642.2 |
IFIH1
|
interferon induced with helicase C domain 1 |
| chr4_-_122085469 | 2.77 |
ENST00000057513.3
|
TNIP3
|
TNFAIP3 interacting protein 3 |
| chr8_-_101321584 | 2.76 |
ENST00000523167.1
|
RNF19A
|
ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| chr14_+_55034330 | 2.76 |
ENST00000251091.5
|
SAMD4A
|
sterile alpha motif domain containing 4A |
| chr6_+_29691056 | 2.70 |
ENST00000414333.1
ENST00000334668.4 ENST00000259951.7 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr6_+_31555045 | 2.69 |
ENST00000396101.3
ENST00000490742.1 |
LST1
|
leukocyte specific transcript 1 |
| chr10_+_13142075 | 2.64 |
ENST00000378757.2
ENST00000430081.1 ENST00000378752.3 ENST00000378748.3 |
OPTN
|
optineurin |
| chr17_-_34207295 | 2.62 |
ENST00000463941.1
ENST00000293272.3 |
CCL5
|
chemokine (C-C motif) ligand 5 |
| chr21_+_34775698 | 2.61 |
ENST00000381995.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr2_+_26568965 | 2.56 |
ENST00000260585.7
ENST00000447170.1 |
EPT1
|
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) |
| chr10_+_13141585 | 2.55 |
ENST00000378764.2
|
OPTN
|
optineurin |
| chr10_+_13142225 | 2.55 |
ENST00000378747.3
|
OPTN
|
optineurin |
| chr7_-_98741642 | 2.54 |
ENST00000361368.2
|
SMURF1
|
SMAD specific E3 ubiquitin protein ligase 1 |
| chr22_-_50964849 | 2.53 |
ENST00000543927.1
ENST00000423348.1 |
SCO2
|
SCO2 cytochrome c oxidase assembly protein |
| chr2_+_161993412 | 2.52 |
ENST00000259075.2
ENST00000432002.1 |
TANK
|
TRAF family member-associated NFKB activator |
| chr1_-_159893507 | 2.52 |
ENST00000368096.1
|
TAGLN2
|
transgelin 2 |
| chr2_+_32853093 | 2.50 |
ENST00000448773.1
ENST00000317907.4 |
TTC27
|
tetratricopeptide repeat domain 27 |
| chr8_+_54793454 | 2.50 |
ENST00000276500.4
|
RGS20
|
regulator of G-protein signaling 20 |
| chr21_+_34775772 | 2.47 |
ENST00000405436.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr8_+_54793425 | 2.47 |
ENST00000522225.1
|
RGS20
|
regulator of G-protein signaling 20 |
| chr11_-_57194218 | 2.46 |
ENST00000529554.1
|
SLC43A3
|
solute carrier family 43, member 3 |
| chr1_+_110453462 | 2.42 |
ENST00000488198.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr13_+_44453969 | 2.35 |
ENST00000325686.6
|
LACC1
|
laccase (multicopper oxidoreductase) domain containing 1 |
| chr20_+_44746939 | 2.33 |
ENST00000372276.3
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5 |
| chr5_+_49962495 | 2.32 |
ENST00000515175.1
|
PARP8
|
poly (ADP-ribose) polymerase family, member 8 |
| chr12_-_50101003 | 2.32 |
ENST00000550488.1
|
FMNL3
|
formin-like 3 |
| chr7_-_98741714 | 2.30 |
ENST00000361125.1
|
SMURF1
|
SMAD specific E3 ubiquitin protein ligase 1 |
| chr12_-_111021110 | 2.30 |
ENST00000354300.3
|
PPTC7
|
PTC7 protein phosphatase homolog (S. cerevisiae) |
| chr8_+_86121448 | 2.23 |
ENST00000520225.1
|
E2F5
|
E2F transcription factor 5, p130-binding |
| chr10_-_100027943 | 2.20 |
ENST00000260702.3
|
LOXL4
|
lysyl oxidase-like 4 |
| chr22_-_19512893 | 2.17 |
ENST00000403084.1
ENST00000413119.2 |
CLDN5
|
claudin 5 |
| chr5_-_138862326 | 2.15 |
ENST00000330794.4
|
TMEM173
|
transmembrane protein 173 |
| chr2_+_102314161 | 2.13 |
ENST00000425019.1
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4 |
| chr11_-_75062829 | 2.12 |
ENST00000393505.4
|
ARRB1
|
arrestin, beta 1 |
| chr22_-_38380543 | 2.08 |
ENST00000396884.2
|
SOX10
|
SRY (sex determining region Y)-box 10 |
| chr6_+_31554456 | 2.08 |
ENST00000339530.4
|
LST1
|
leukocyte specific transcript 1 |
| chr11_+_75526212 | 2.07 |
ENST00000356136.3
|
UVRAG
|
UV radiation resistance associated |
| chr22_+_41075277 | 2.05 |
ENST00000381433.2
|
MCHR1
|
melanin-concentrating hormone receptor 1 |
| chr14_-_24616426 | 2.02 |
ENST00000216802.5
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr2_+_68694678 | 2.02 |
ENST00000303795.4
|
APLF
|
aprataxin and PNKP like factor |
| chr6_-_33290580 | 1.96 |
ENST00000446511.1
ENST00000446403.1 ENST00000414083.2 ENST00000266000.6 ENST00000374542.5 |
DAXX
|
death-domain associated protein |
| chr3_-_58563094 | 1.91 |
ENST00000464064.1
|
FAM107A
|
family with sequence similarity 107, member A |
| chr3_+_9691117 | 1.87 |
ENST00000353332.5
ENST00000420925.1 ENST00000296003.4 ENST00000351233.5 |
MTMR14
|
myotubularin related protein 14 |
| chr19_+_45147313 | 1.87 |
ENST00000406449.4
|
PVR
|
poliovirus receptor |
| chr19_+_45254529 | 1.86 |
ENST00000444487.1
|
BCL3
|
B-cell CLL/lymphoma 3 |
| chr17_+_21191341 | 1.85 |
ENST00000526076.2
ENST00000361818.5 ENST00000316920.6 |
MAP2K3
|
mitogen-activated protein kinase kinase 3 |
| chr4_+_4861385 | 1.85 |
ENST00000382723.4
|
MSX1
|
msh homeobox 1 |
| chr11_-_75062730 | 1.84 |
ENST00000420843.2
ENST00000360025.3 |
ARRB1
|
arrestin, beta 1 |
| chr6_+_29910301 | 1.83 |
ENST00000376809.5
ENST00000376802.2 |
HLA-A
|
major histocompatibility complex, class I, A |
| chr4_+_39046615 | 1.80 |
ENST00000261425.3
ENST00000508137.2 |
KLHL5
|
kelch-like family member 5 |
| chr4_-_80994210 | 1.78 |
ENST00000403729.2
|
ANTXR2
|
anthrax toxin receptor 2 |
| chr20_+_44746885 | 1.77 |
ENST00000372285.3
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5 |
| chr10_+_90750378 | 1.76 |
ENST00000355740.2
ENST00000352159.4 |
FAS
|
Fas cell surface death receptor |
| chr3_-_46068969 | 1.73 |
ENST00000542109.1
ENST00000395946.2 |
XCR1
|
chemokine (C motif) receptor 1 |
| chr2_-_220252603 | 1.72 |
ENST00000322176.7
ENST00000273075.4 |
DNPEP
|
aspartyl aminopeptidase |
| chr7_-_100493744 | 1.70 |
ENST00000428317.1
ENST00000441605.1 |
ACHE
|
acetylcholinesterase (Yt blood group) |
| chr15_-_77712477 | 1.69 |
ENST00000560626.2
|
PEAK1
|
pseudopodium-enriched atypical kinase 1 |
| chr19_+_39390320 | 1.68 |
ENST00000576510.1
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| chr11_-_46142505 | 1.63 |
ENST00000524497.1
ENST00000418153.2 |
PHF21A
|
PHD finger protein 21A |
| chr15_-_41408409 | 1.62 |
ENST00000361937.3
|
INO80
|
INO80 complex subunit |
| chr9_-_32526299 | 1.62 |
ENST00000379882.1
ENST00000379883.2 |
DDX58
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| chr20_+_327668 | 1.62 |
ENST00000382291.3
ENST00000609504.1 ENST00000382285.2 |
NRSN2
|
neurensin 2 |
| chr16_+_56970567 | 1.59 |
ENST00000563911.1
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| chr8_+_120079478 | 1.53 |
ENST00000332843.2
|
COLEC10
|
collectin sub-family member 10 (C-type lectin) |
| chr14_-_35873856 | 1.52 |
ENST00000553342.1
ENST00000216797.5 ENST00000557140.1 |
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| chr6_-_4079334 | 1.50 |
ENST00000492651.1
ENST00000498677.1 ENST00000274673.3 |
FAM217A
|
family with sequence similarity 217, member A |
| chr19_+_39390587 | 1.46 |
ENST00000572515.1
ENST00000392079.3 ENST00000575359.1 ENST00000313582.5 |
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| chr4_+_155484155 | 1.45 |
ENST00000509493.1
|
FGB
|
fibrinogen beta chain |
| chr20_+_2795626 | 1.42 |
ENST00000603872.1
ENST00000380589.4 |
C20orf141
|
chromosome 20 open reading frame 141 |
| chr12_+_53662110 | 1.40 |
ENST00000552462.1
|
ESPL1
|
extra spindle pole bodies homolog 1 (S. cerevisiae) |
| chr12_+_53662073 | 1.40 |
ENST00000553219.1
ENST00000257934.4 |
ESPL1
|
extra spindle pole bodies homolog 1 (S. cerevisiae) |
| chr7_+_7606497 | 1.39 |
ENST00000340080.4
ENST00000405785.1 ENST00000433635.1 |
MIOS
|
missing oocyte, meiosis regulator, homolog (Drosophila) |
| chr1_+_183441600 | 1.38 |
ENST00000367537.3
|
SMG7
|
SMG7 nonsense mediated mRNA decay factor |
| chr2_-_74753332 | 1.38 |
ENST00000451518.1
ENST00000404568.3 |
DQX1
|
DEAQ box RNA-dependent ATPase 1 |
| chr2_+_5832799 | 1.38 |
ENST00000322002.3
|
SOX11
|
SRY (sex determining region Y)-box 11 |
| chr2_-_74753305 | 1.38 |
ENST00000393951.2
|
DQX1
|
DEAQ box RNA-dependent ATPase 1 |
| chr22_+_18043133 | 1.37 |
ENST00000327451.6
ENST00000399813.1 |
SLC25A18
|
solute carrier family 25 (glutamate carrier), member 18 |
| chr22_+_50919944 | 1.36 |
ENST00000395738.2
|
ADM2
|
adrenomedullin 2 |
| chr4_+_5053162 | 1.35 |
ENST00000282908.5
|
STK32B
|
serine/threonine kinase 32B |
| chr10_+_114133773 | 1.34 |
ENST00000354655.4
|
ACSL5
|
acyl-CoA synthetase long-chain family member 5 |
| chr6_+_26538566 | 1.34 |
ENST00000377575.2
|
HMGN4
|
high mobility group nucleosomal binding domain 4 |
| chr17_-_1389419 | 1.34 |
ENST00000575158.1
|
MYO1C
|
myosin IC |
| chr21_+_44589118 | 1.34 |
ENST00000291554.2
|
CRYAA
|
crystallin, alpha A |
| chr2_-_200820459 | 1.33 |
ENST00000354611.4
|
TYW5
|
tRNA-yW synthesizing protein 5 |
| chr3_-_11623804 | 1.32 |
ENST00000451674.2
|
VGLL4
|
vestigial like 4 (Drosophila) |
| chr11_-_3862206 | 1.31 |
ENST00000351018.4
|
RHOG
|
ras homolog family member G |
| chr19_-_40724246 | 1.30 |
ENST00000311308.6
|
TTC9B
|
tetratricopeptide repeat domain 9B |
| chr6_+_160327974 | 1.29 |
ENST00000252660.4
|
MAS1
|
MAS1 oncogene |
| chr6_+_31554612 | 1.29 |
ENST00000211921.7
|
LST1
|
leukocyte specific transcript 1 |
| chr22_+_37257015 | 1.29 |
ENST00000447071.1
ENST00000248899.6 ENST00000397147.4 |
NCF4
|
neutrophil cytosolic factor 4, 40kDa |
| chr14_+_103243813 | 1.28 |
ENST00000560371.1
ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1 |
TRAF3
|
TNF receptor-associated factor 3 |
| chr9_-_34381511 | 1.27 |
ENST00000379124.1
|
C9orf24
|
chromosome 9 open reading frame 24 |
| chr17_-_55822653 | 1.26 |
ENST00000299415.2
|
AC007431.1
|
coiled-coil domain containing 182 |
| chr5_+_69321361 | 1.26 |
ENST00000515588.1
|
SERF1B
|
small EDRK-rich factor 1B (centromeric) |
| chr16_+_57392684 | 1.26 |
ENST00000219235.4
|
CCL22
|
chemokine (C-C motif) ligand 22 |
| chr6_-_43484621 | 1.23 |
ENST00000506469.1
ENST00000503972.1 |
YIPF3
|
Yip1 domain family, member 3 |
| chr9_-_37465396 | 1.21 |
ENST00000307750.4
|
ZBTB5
|
zinc finger and BTB domain containing 5 |
| chr2_-_169887827 | 1.21 |
ENST00000263817.6
|
ABCB11
|
ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
| chr12_-_63328817 | 1.20 |
ENST00000228705.6
|
PPM1H
|
protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| chr15_-_50411412 | 1.20 |
ENST00000284509.6
|
ATP8B4
|
ATPase, class I, type 8B, member 4 |
| chr17_-_1389228 | 1.19 |
ENST00000438665.2
|
MYO1C
|
myosin IC |
| chr22_+_50919995 | 1.19 |
ENST00000362068.2
ENST00000395737.1 |
ADM2
|
adrenomedullin 2 |
| chr21_-_43373999 | 1.17 |
ENST00000380486.3
|
C2CD2
|
C2 calcium-dependent domain containing 2 |
| chrX_+_48367338 | 1.16 |
ENST00000359882.4
ENST00000537758.1 ENST00000367574.4 ENST00000355961.4 ENST00000489940.1 ENST00000361988.3 |
PORCN
|
porcupine homolog (Drosophila) |
| chr3_+_9773409 | 1.16 |
ENST00000433861.2
ENST00000424362.1 ENST00000383829.2 ENST00000302054.3 ENST00000420291.1 |
BRPF1
|
bromodomain and PHD finger containing, 1 |
| chr4_+_169552748 | 1.16 |
ENST00000504519.1
ENST00000512127.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr19_-_10445399 | 1.16 |
ENST00000592945.1
|
ICAM3
|
intercellular adhesion molecule 3 |
| chr2_-_235405679 | 1.15 |
ENST00000390645.2
|
ARL4C
|
ADP-ribosylation factor-like 4C |
| chr7_-_150497406 | 1.15 |
ENST00000492607.1
ENST00000326442.5 ENST00000450753.2 |
TMEM176B
|
transmembrane protein 176B |
| chr2_+_152266604 | 1.15 |
ENST00000430328.2
|
RIF1
|
RAP1 interacting factor homolog (yeast) |
| chr11_+_64052266 | 1.11 |
ENST00000539851.1
|
GPR137
|
G protein-coupled receptor 137 |
| chr7_-_150497621 | 1.10 |
ENST00000434545.1
|
TMEM176B
|
transmembrane protein 176B |
| chr6_+_31554636 | 1.10 |
ENST00000433492.1
|
LST1
|
leukocyte specific transcript 1 |
| chr3_-_119813264 | 1.09 |
ENST00000264235.8
|
GSK3B
|
glycogen synthase kinase 3 beta |
| chr10_-_75401500 | 1.09 |
ENST00000359322.4
|
MYOZ1
|
myozenin 1 |
| chr9_-_34381536 | 1.09 |
ENST00000379126.3
ENST00000379127.1 ENST00000379133.3 |
C9orf24
|
chromosome 9 open reading frame 24 |
| chr2_-_100721178 | 1.08 |
ENST00000409236.2
|
AFF3
|
AF4/FMR2 family, member 3 |
| chr2_+_64681641 | 1.07 |
ENST00000409537.2
|
LGALSL
|
lectin, galactoside-binding-like |
| chr1_+_183441500 | 1.07 |
ENST00000456731.2
|
SMG7
|
SMG7 nonsense mediated mRNA decay factor |
| chr17_+_6926339 | 1.06 |
ENST00000293805.5
|
BCL6B
|
B-cell CLL/lymphoma 6, member B |
| chr3_-_119278376 | 1.05 |
ENST00000478182.1
|
CD80
|
CD80 molecule |
| chr6_-_43484718 | 1.05 |
ENST00000372422.2
|
YIPF3
|
Yip1 domain family, member 3 |
| chr1_+_100818156 | 1.05 |
ENST00000336454.3
|
CDC14A
|
cell division cycle 14A |
| chr1_-_159894319 | 1.04 |
ENST00000320307.4
|
TAGLN2
|
transgelin 2 |
| chr1_-_21616690 | 1.04 |
ENST00000264205.6
|
ECE1
|
endothelin converting enzyme 1 |
| chr16_-_1275257 | 1.03 |
ENST00000234798.4
|
TPSG1
|
tryptase gamma 1 |
| chr1_-_36851475 | 1.03 |
ENST00000373129.3
|
STK40
|
serine/threonine kinase 40 |
| chr11_+_64052692 | 1.02 |
ENST00000377702.4
|
GPR137
|
G protein-coupled receptor 137 |
| chr11_-_61735103 | 1.01 |
ENST00000529191.1
ENST00000529631.1 ENST00000530019.1 ENST00000529548.1 ENST00000273550.7 |
FTH1
|
ferritin, heavy polypeptide 1 |
| chr17_-_39093672 | 1.01 |
ENST00000209718.3
ENST00000436344.3 ENST00000485751.1 |
KRT23
|
keratin 23 (histone deacetylase inducible) |
| chr3_-_157221357 | 1.00 |
ENST00000494677.1
|
VEPH1
|
ventricular zone expressed PH domain-containing 1 |
| chr15_+_59063478 | 1.00 |
ENST00000559228.1
ENST00000450403.2 |
FAM63B
|
family with sequence similarity 63, member B |
| chr4_+_55095264 | 0.98 |
ENST00000257290.5
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide |
| chr4_-_80993717 | 0.97 |
ENST00000307333.7
|
ANTXR2
|
anthrax toxin receptor 2 |
| chr11_+_32914579 | 0.97 |
ENST00000399302.2
|
QSER1
|
glutamine and serine rich 1 |
| chr17_+_6918354 | 0.96 |
ENST00000552775.1
|
C17orf49
|
chromosome 17 open reading frame 49 |
| chr3_-_157221380 | 0.96 |
ENST00000468233.1
|
VEPH1
|
ventricular zone expressed PH domain-containing 1 |
| chr7_+_100271446 | 0.94 |
ENST00000419828.1
ENST00000427895.1 |
GNB2
|
guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| chrX_-_15353629 | 0.93 |
ENST00000333590.4
ENST00000428964.1 ENST00000542278.1 |
PIGA
|
phosphatidylinositol glycan anchor biosynthesis, class A |
| chr2_+_106468204 | 0.93 |
ENST00000425756.1
ENST00000393349.2 |
NCK2
|
NCK adaptor protein 2 |
| chr3_-_119396193 | 0.92 |
ENST00000484810.1
ENST00000497116.1 ENST00000261070.2 |
COX17
|
COX17 cytochrome c oxidase copper chaperone |
| chr19_-_12833164 | 0.92 |
ENST00000356861.5
|
TNPO2
|
transportin 2 |
| chr12_+_10658201 | 0.91 |
ENST00000322446.3
|
EIF2S3L
|
Putative eukaryotic translation initiation factor 2 subunit 3-like protein |
| chr20_+_18488528 | 0.91 |
ENST00000377465.1
|
SEC23B
|
Sec23 homolog B (S. cerevisiae) |
| chr3_-_9291063 | 0.89 |
ENST00000383836.3
|
SRGAP3
|
SLIT-ROBO Rho GTPase activating protein 3 |
| chr18_+_11490077 | 0.89 |
ENST00000586947.1
ENST00000591431.1 |
RP11-712C7.1
|
RP11-712C7.1 |
| chr11_+_58910201 | 0.89 |
ENST00000528737.1
|
FAM111A
|
family with sequence similarity 111, member A |
| chr15_+_59730348 | 0.88 |
ENST00000288228.5
ENST00000559628.1 ENST00000557914.1 ENST00000560474.1 |
FAM81A
|
family with sequence similarity 81, member A |
| chr1_+_155006300 | 0.88 |
ENST00000295542.1
ENST00000392480.1 ENST00000423025.2 ENST00000368419.2 |
DCST1
|
DC-STAMP domain containing 1 |
| chr14_-_69445793 | 0.87 |
ENST00000538545.2
ENST00000394419.4 |
ACTN1
|
actinin, alpha 1 |
| chr17_+_6918064 | 0.86 |
ENST00000546760.1
ENST00000552402.1 |
C17orf49
|
chromosome 17 open reading frame 49 |
| chr5_+_69321074 | 0.86 |
ENST00000380751.5
ENST00000380750.3 ENST00000503931.1 ENST00000506542.1 |
SERF1B
|
small EDRK-rich factor 1B (centromeric) |
| chr17_+_17685422 | 0.86 |
ENST00000395774.1
|
RAI1
|
retinoic acid induced 1 |
| chr12_-_54982300 | 0.86 |
ENST00000547431.1
|
PPP1R1A
|
protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| chr12_-_48298785 | 0.85 |
ENST00000550325.1
ENST00000546653.1 ENST00000549336.1 ENST00000535672.1 ENST00000229022.3 ENST00000548664.1 |
VDR
|
vitamin D (1,25- dihydroxyvitamin D3) receptor |
| chr11_-_67276100 | 0.84 |
ENST00000301488.3
|
CDK2AP2
|
cyclin-dependent kinase 2 associated protein 2 |
| chr5_-_58652788 | 0.84 |
ENST00000405755.2
|
PDE4D
|
phosphodiesterase 4D, cAMP-specific |
Network of associatons between targets according to the STRING database.
First level regulatory network of HIVEP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 14.1 | GO:0085032 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 2.3 | 9.0 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 2.2 | 11.0 | GO:0060611 | mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 2.1 | 6.2 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 2.0 | 8.1 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 1.6 | 4.8 | GO:1902534 | single-organism membrane invagination(GO:1902534) |
| 1.4 | 8.2 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183) |
| 1.3 | 13.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.3 | 11.8 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 1.2 | 14.6 | GO:0010819 | regulation of T cell chemotaxis(GO:0010819) |
| 1.1 | 4.6 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 1.1 | 3.3 | GO:1902523 | detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 1.1 | 3.2 | GO:0070428 | B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 1.0 | 6.1 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 1.0 | 2.9 | GO:0035552 | oxidative single-stranded DNA demethylation(GO:0035552) |
| 0.9 | 7.7 | GO:0061734 | negative regulation of receptor recycling(GO:0001920) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) |
| 0.8 | 9.7 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.8 | 8.8 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.7 | 2.8 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.6 | 17.6 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.6 | 1.9 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.6 | 1.9 | GO:0045082 | positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
| 0.6 | 1.8 | GO:0090427 | activation of meiosis(GO:0090427) |
| 0.6 | 4.1 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.6 | 1.7 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.5 | 2.2 | GO:1903935 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 0.5 | 2.1 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.5 | 1.5 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.5 | 3.9 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.5 | 1.4 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.4 | 2.5 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.4 | 1.1 | GO:0071109 | superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.3 | 2.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.3 | 4.0 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.3 | 5.6 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.3 | 1.8 | GO:0097527 | Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527) |
| 0.3 | 0.8 | GO:1903519 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.3 | 2.8 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.3 | 0.8 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.3 | 2.2 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 1.0 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.3 | 2.0 | GO:0051106 | positive regulation of DNA ligation(GO:0051106) |
| 0.3 | 0.8 | GO:0003050 | regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050) |
| 0.2 | 1.0 | GO:0072275 | metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 0.2 | 1.9 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.2 | 6.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 1.8 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.2 | 1.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.2 | 2.1 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.2 | 1.6 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.2 | 0.6 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.2 | 1.2 | GO:0045425 | positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) |
| 0.2 | 1.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.2 | 5.7 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.2 | 0.5 | GO:0060127 | subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) |
| 0.2 | 1.0 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.2 | 17.3 | GO:0032945 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.2 | 0.6 | GO:0061743 | motor learning(GO:0061743) |
| 0.2 | 0.6 | GO:0009726 | detection of endogenous stimulus(GO:0009726) |
| 0.2 | 0.9 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.1 | 0.4 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 2.1 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.1 | 0.3 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 0.1 | 0.4 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) |
| 0.1 | 2.5 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.1 | 4.4 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.1 | 2.2 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 1.6 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 4.5 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 5.1 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.5 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.1 | 0.7 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.1 | 0.4 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.1 | 0.8 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 0.1 | 1.9 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 1.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 6.1 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 1.6 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 7.5 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.1 | 1.2 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.1 | 1.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.1 | 1.0 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.6 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.1 | 0.9 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.1 | 0.3 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.1 | 0.8 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 2.8 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
| 0.1 | 0.8 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 1.0 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 0.6 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 0.5 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 7.4 | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) |
| 0.1 | 0.5 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 1.4 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 0.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 1.2 | GO:0033630 | positive regulation of cell adhesion mediated by integrin(GO:0033630) |
| 0.1 | 1.2 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.1 | 1.3 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.1 | 0.8 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 0.3 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 2.1 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.1 | 1.4 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.1 | 0.4 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 0.5 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 0.7 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 0.7 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.1 | 0.2 | GO:0033967 | box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258) |
| 0.1 | 0.1 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.1 | 0.2 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
| 0.1 | 0.2 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 0.4 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.1 | 0.9 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.1 | 0.3 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 0.1 | 3.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 0.9 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 1.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 2.5 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.1 | 0.2 | GO:0045229 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.1 | 0.3 | GO:2001184 | positive regulation of interleukin-12 secretion(GO:2001184) |
| 0.1 | 0.7 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.1 | 0.1 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.1 | 1.5 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 0.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.0 | 0.5 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.0 | 0.7 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.0 | 0.2 | GO:1901623 | regulation of lymphocyte chemotaxis(GO:1901623) |
| 0.0 | 0.2 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.0 | 0.0 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 0.0 | 0.2 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.0 | 1.3 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 4.4 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.0 | 0.9 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.7 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.0 | 0.9 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.4 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.0 | 0.2 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.0 | 0.1 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.0 | 2.8 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 1.0 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 2.4 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 0.1 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
| 0.0 | 1.3 | GO:0042026 | protein refolding(GO:0042026) |
| 0.0 | 0.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.0 | 0.2 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.2 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.0 | 2.4 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 1.0 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.0 | 2.0 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 1.6 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.0 | 1.2 | GO:0071173 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.0 | 0.1 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.0 | 0.1 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.0 | 0.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.0 | 0.3 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.0 | 0.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.3 | GO:0050716 | positive regulation of interleukin-1 secretion(GO:0050716) |
| 0.0 | 0.1 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.0 | 0.6 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.0 | 0.2 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 4.4 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.4 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 0.5 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.0 | 0.5 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.0 | 0.4 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.0 | 0.0 | GO:0045359 | negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.0 | 2.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.0 | GO:0002503 | peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.0 | 1.3 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.0 | 0.9 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.1 | GO:0040032 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.0 | 0.5 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 0.1 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:0021554 | optic nerve development(GO:0021554) |
| 0.0 | 0.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.0 | 0.4 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.5 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.0 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.0 | 0.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 0.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.4 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.1 | GO:1990034 | calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034) |
| 0.0 | 0.0 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 0.0 | 0.5 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.4 | GO:0030208 | chondroitin sulfate catabolic process(GO:0030207) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 1.5 | GO:0006497 | protein lipidation(GO:0006497) |
| 0.0 | 1.8 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.2 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 1.8 | 11.0 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.2 | 13.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.9 | 9.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.8 | 6.7 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.6 | 2.5 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.6 | 4.4 | GO:0098560 | cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.5 | 11.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.5 | 3.7 | GO:0043196 | varicosity(GO:0043196) |
| 0.5 | 1.9 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.4 | 1.2 | GO:1990298 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 0.4 | 2.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.3 | 1.4 | GO:0008043 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.3 | 2.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.3 | 1.6 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.3 | 1.0 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.2 | 6.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 0.8 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.2 | 2.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.2 | 1.3 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.2 | 5.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 1.2 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.1 | 0.6 | GO:0031251 | PAN complex(GO:0031251) |
| 0.1 | 1.7 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.9 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 2.1 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 0.6 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.1 | 0.7 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.1 | 1.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 8.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 1.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.3 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.1 | 1.2 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 0.5 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 0.1 | 1.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 1.0 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.9 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 27.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 13.0 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 2.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 1.6 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.1 | 0.7 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 0.2 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.5 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 0.6 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 1.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.5 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 3.3 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.8 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.8 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.0 | 0.8 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 5.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.3 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.0 | 2.3 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 1.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 1.4 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 1.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 3.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 3.7 | GO:0070160 | occluding junction(GO:0070160) |
| 0.0 | 1.2 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 1.9 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 2.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 1.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.7 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.0 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.0 | 3.3 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 1.5 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 1.4 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.8 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 4.1 | GO:0045121 | membrane raft(GO:0045121) |
| 0.0 | 1.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 2.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 1.4 | GO:0031902 | late endosome membrane(GO:0031902) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 12.0 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.5 | 17.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 1.4 | 11.0 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 1.3 | 4.0 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 1.0 | 6.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 1.0 | 5.1 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.8 | 10.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.8 | 5.7 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.8 | 2.4 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.6 | 8.8 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.5 | 3.1 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.5 | 27.6 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.4 | 1.7 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.4 | 2.6 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.4 | 14.0 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 4.9 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.3 | 2.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.3 | 0.9 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 0.3 | 1.4 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.3 | 4.8 | GO:0048185 | activin binding(GO:0048185) |
| 0.3 | 2.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 1.0 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.2 | 1.0 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.2 | 1.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.2 | 2.5 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.2 | 1.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.2 | 3.1 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.2 | 9.5 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.2 | 1.3 | GO:0004945 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.2 | 1.2 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 0.2 | 0.8 | GO:0038181 | bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644) |
| 0.2 | 0.8 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.2 | 1.4 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 0.9 | GO:0016531 | metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531) |
| 0.1 | 1.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 0.8 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 4.2 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 0.5 | GO:0008732 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.1 | 0.5 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.1 | 0.8 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 1.0 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 2.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 23.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 0.4 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 0.3 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.1 | 2.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 2.0 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 1.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.7 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 1.5 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 2.0 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.1 | 2.0 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.1 | 3.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 4.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 1.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 0.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.1 | 0.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.1 | 0.2 | GO:1990259 | protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259) |
| 0.1 | 2.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 2.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 1.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.9 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.9 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.1 | 1.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 2.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 2.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 8.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.1 | 1.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 1.3 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 1.0 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 1.0 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.2 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 0.7 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.2 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.0 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 1.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.3 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.8 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 1.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 7.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 5.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 9.7 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 2.1 | GO:0030551 | cyclic nucleotide binding(GO:0030551) |
| 0.0 | 1.2 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 1.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 3.3 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.0 | 1.2 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.7 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.3 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.2 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 1.6 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 3.9 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.2 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 0.0 | 1.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 2.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.0 | 0.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.7 | GO:0043236 | laminin binding(GO:0043236) |
| 0.0 | 0.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 1.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 1.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.3 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.5 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.3 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.0 | 1.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 2.3 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 0.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.3 | GO:0008200 | ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248) |
| 0.0 | 0.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 1.0 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.3 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 4.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 1.9 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.5 | 27.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.3 | 11.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.3 | 8.8 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.2 | 17.8 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 5.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 3.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.2 | 3.6 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.2 | 5.9 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.2 | 6.3 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.1 | 8.1 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 2.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 7.4 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 3.6 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 1.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 4.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 2.0 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 1.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 1.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 19.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.1 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.9 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 4.2 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 2.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.1 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 1.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.2 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.2 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.2 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 13.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.5 | 34.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.5 | 10.3 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.4 | 8.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 1.2 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.2 | 4.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 7.8 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.2 | 4.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.2 | 8.3 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.2 | 4.8 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 2.1 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 3.3 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 2.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 3.0 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 3.2 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.1 | 5.7 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 4.4 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 3.7 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.8 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 10.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 1.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 1.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 2.2 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 3.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 2.2 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 1.7 | REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| 0.0 | 1.2 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.8 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.0 | 0.8 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 2.8 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.9 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 2.6 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.8 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.7 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.0 | 1.3 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.0 | 3.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.9 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 2.6 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.4 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.4 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 1.2 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.5 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.8 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.4 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 2.3 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.3 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.0 | 0.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |