Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for HMBOX1

Z-value: 0.56

Motif logo

logo of

Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
HMBOX1
ENSG00000147421.13 homeobox containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg19_v2_chr8_+_28747884_28747938-0.193.8e-01Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_22234381 1.01 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_-_56236734 0.79 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr2_+_162087577 0.76 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr14_+_22615942 0.63 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr1_-_173176452 0.61 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr7_+_128095900 0.56 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr8_-_63951730 0.55 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr9_-_73029540 0.55 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr7_+_128095945 0.48 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr11_+_19798964 0.47 ENST00000527559.2
NAV2
neuron navigator 2
chr11_-_57194948 0.44 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
SLC43A3
solute carrier family 43, member 3
chr7_+_134576317 0.42 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr4_-_114900831 0.41 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr12_+_51633061 0.40 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr8_+_94929969 0.39 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_+_75874580 0.38 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr19_-_56826157 0.37 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr7_+_100728720 0.37 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr7_-_47579188 0.36 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3
tensin 3
chr15_-_89764929 0.36 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr14_-_50999307 0.35 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_127413481 0.35 ENST00000259254.4
GYPC
glycophorin C (Gerbich blood group)
chr4_-_159080806 0.35 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr4_+_9172135 0.32 ENST00000512047.1
FAM90A26
family with sequence similarity 90, member A26
chr19_+_16178317 0.31 ENST00000344824.6
ENST00000538887.1
TPM4
tropomyosin 4
chr4_-_10117949 0.30 ENST00000508079.1
WDR1
WD repeat domain 1
chr5_+_138629628 0.30 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chrX_+_70752945 0.30 ENST00000373701.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr20_+_43211149 0.30 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_+_206643787 0.29 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr8_+_66955648 0.29 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr1_+_109632425 0.28 ENST00000338272.8
TMEM167B
transmembrane protein 167B
chr5_+_173316341 0.28 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr9_-_101984184 0.28 ENST00000476832.1
ALG2
ALG2, alpha-1,3/1,6-mannosyltransferase
chr2_-_197226875 0.28 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr19_-_7553852 0.27 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr22_-_36635684 0.27 ENST00000358502.5
APOL2
apolipoprotein L, 2
chr22_-_32334403 0.26 ENST00000543051.1
C22orf24
chromosome 22 open reading frame 24
chr3_-_69101413 0.26 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr1_+_89246647 0.25 ENST00000544045.1
PKN2
protein kinase N2
chr11_+_73087309 0.25 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr5_-_133968459 0.24 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1B
SAR1 homolog B (S. cerevisiae)
chr16_-_30597000 0.24 ENST00000470110.1
ENST00000395216.2
ZNF785
zinc finger protein 785
chr1_-_150669500 0.24 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr12_-_77272765 0.23 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr3_-_69101461 0.23 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr19_-_7553889 0.23 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chrX_-_20236970 0.23 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_38347427 0.22 ENST00000273173.4
SLC22A14
solute carrier family 22, member 14
chr6_-_27114577 0.22 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr4_+_119810134 0.22 ENST00000434046.2
SYNPO2
synaptopodin 2
chr4_+_36283213 0.22 ENST00000357504.3
DTHD1
death domain containing 1
chr21_-_46340884 0.22 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chrX_+_70586140 0.22 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr5_+_140810132 0.22 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr19_-_8214730 0.21 ENST00000600128.1
FBN3
fibrillin 3
chr7_+_134576151 0.21 ENST00000393118.2
CALD1
caldesmon 1
chrX_+_70503037 0.21 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr11_-_5207612 0.21 ENST00000380367.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr7_+_128379449 0.20 ENST00000479257.1
CALU
calumenin
chr1_+_206643806 0.20 ENST00000537984.1
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr10_+_115312766 0.19 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr17_+_3118915 0.19 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr3_-_141747439 0.19 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chrX_+_70503433 0.18 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr14_+_31028348 0.18 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr12_+_117013656 0.18 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chrX_+_135730373 0.18 ENST00000370628.2
CD40LG
CD40 ligand
chr9_-_73477826 0.18 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr14_+_50999744 0.18 ENST00000441560.2
ATL1
atlastin GTPase 1
chrX_+_135730297 0.17 ENST00000370629.2
CD40LG
CD40 ligand
chr1_-_153283194 0.17 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr17_+_42925270 0.17 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chrM_+_5824 0.17 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr4_-_122302163 0.17 ENST00000394427.2
QRFPR
pyroglutamylated RFamide peptide receptor
chrX_-_30877837 0.17 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr15_+_69857515 0.17 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr16_-_18908196 0.17 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr20_+_68306 0.17 ENST00000382410.2
DEFB125
defensin, beta 125
chr10_+_24755416 0.17 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr5_-_137667526 0.16 ENST00000503022.1
CDC25C
cell division cycle 25C
chrX_+_70752917 0.16 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_106468204 0.16 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr1_+_24286287 0.15 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr3_-_45838011 0.15 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr12_-_76879852 0.15 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr1_+_207943667 0.15 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chr16_-_71842941 0.15 ENST00000423132.2
ENST00000433195.2
ENST00000569748.1
ENST00000570017.1
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr3_-_45837959 0.15 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_43803475 0.15 ENST00000372470.3
ENST00000413998.2
MPL
myeloproliferative leukemia virus oncogene
chr1_-_217250231 0.15 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chrX_-_15683147 0.15 ENST00000380342.3
TMEM27
transmembrane protein 27
chr6_+_29364416 0.15 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr1_+_175036966 0.15 ENST00000239462.4
TNN
tenascin N
chrX_-_99987088 0.14 ENST00000372981.1
ENST00000263033.5
SYTL4
synaptotagmin-like 4
chr1_+_87595542 0.14 ENST00000461990.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr20_-_43133491 0.14 ENST00000411544.1
SERINC3
serine incorporator 3
chr4_+_144303093 0.13 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr3_+_33155525 0.13 ENST00000449224.1
CRTAP
cartilage associated protein
chr6_-_107235287 0.13 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr8_+_30244580 0.13 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr2_+_68384976 0.13 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr12_+_72080253 0.12 ENST00000549735.1
TMEM19
transmembrane protein 19
chr2_+_159825143 0.12 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr5_+_140762268 0.12 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr7_-_28220354 0.12 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr17_-_55822653 0.12 ENST00000299415.2
AC007431.1
coiled-coil domain containing 182
chr10_+_124913793 0.12 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr20_+_61584026 0.12 ENST00000370351.4
ENST00000370349.3
SLC17A9
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr1_+_27561104 0.12 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr19_-_18654293 0.12 ENST00000597547.1
ENST00000222308.4
ENST00000544835.3
ENST00000610101.1
ENST00000597960.3
ENST00000608443.1
FKBP8
FK506 binding protein 8, 38kDa
chr1_-_167487758 0.12 ENST00000362089.5
CD247
CD247 molecule
chr11_-_58345569 0.12 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr6_+_134758827 0.12 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr1_-_150669604 0.12 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chrX_+_78426469 0.12 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr1_+_87595497 0.11 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr19_-_35992780 0.11 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr1_-_217311090 0.11 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr13_-_108870623 0.11 ENST00000405925.1
LIG4
ligase IV, DNA, ATP-dependent
chr21_+_45725050 0.11 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr2_-_220110187 0.11 ENST00000295759.7
ENST00000392089.2
GLB1L
galactosidase, beta 1-like
chr4_+_74301880 0.11 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr10_+_89419370 0.11 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_+_111303218 0.11 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr17_+_41177220 0.11 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr11_-_64825993 0.11 ENST00000340252.4
ENST00000355721.3
ENST00000356632.3
ENST00000355369.2
ENST00000339885.2
ENST00000358658.3
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr1_+_116654376 0.11 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr17_-_10452929 0.11 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr4_+_120860695 0.11 ENST00000505122.2
RP11-700N1.1
RP11-700N1.1
chr2_-_214016314 0.11 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_+_182850551 0.11 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_-_220110111 0.11 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr2_+_234686976 0.10 ENST00000389758.3
MROH2A
maestro heat-like repeat family member 2A
chr6_-_107235331 0.10 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr1_+_222988363 0.10 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3
RP11-452F19.3
chr1_+_27561007 0.10 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr17_+_26800648 0.10 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_-_6240183 0.10 ENST00000262450.3
ENST00000378021.1
CHD5
chromodomain helicase DNA binding protein 5
chr3_+_38537960 0.10 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr2_+_192543153 0.10 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr17_+_26800756 0.10 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr12_-_62586543 0.10 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr2_+_36923933 0.10 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr12_-_54673871 0.10 ENST00000209875.4
CBX5
chromobox homolog 5
chr7_-_102985288 0.10 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr20_+_42187682 0.09 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr3_-_57326704 0.09 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr8_+_107460147 0.09 ENST00000442977.2
OXR1
oxidation resistance 1
chr10_-_112678904 0.09 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr6_+_167536230 0.09 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr5_+_138629417 0.09 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr20_+_42187608 0.09 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_26199737 0.09 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr16_-_71843047 0.09 ENST00000299980.4
ENST00000393512.3
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_-_152009460 0.09 ENST00000271638.2
S100A11
S100 calcium binding protein A11
chr17_+_26800296 0.09 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_+_222988464 0.09 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr22_-_37880543 0.09 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_+_48611665 0.08 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr4_-_152149033 0.08 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr1_-_32384693 0.08 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr12_-_88423164 0.08 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr2_+_113825547 0.08 ENST00000341010.2
ENST00000337569.3
IL1F10
interleukin 1 family, member 10 (theta)
chr14_-_45431091 0.08 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr2_-_99952769 0.08 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
TXNDC9
thioredoxin domain containing 9
chr14_+_75536280 0.08 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr1_+_196743943 0.08 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr12_+_49121213 0.08 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chrX_+_70586082 0.08 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr17_-_29641084 0.08 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr17_+_3572087 0.07 ENST00000248378.5
ENST00000397133.2
EMC6
ER membrane protein complex subunit 6
chr8_-_67874805 0.07 ENST00000563496.1
TCF24
transcription factor 24
chr14_-_57272366 0.07 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr16_+_21689835 0.07 ENST00000286149.4
ENST00000388958.3
OTOA
otoancorin
chr14_+_75536335 0.07 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr10_+_112679301 0.07 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr6_-_52668605 0.07 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr6_+_138725343 0.07 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr1_+_196743912 0.07 ENST00000367425.4
CFHR3
complement factor H-related 3
chr18_-_31803435 0.07 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4
nucleolar protein 4
chr10_-_94257512 0.06 ENST00000371581.5
IDE
insulin-degrading enzyme
chr17_+_6544078 0.06 ENST00000250101.5
TXNDC17
thioredoxin domain containing 17
chr12_-_10588539 0.06 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr2_+_127782787 0.06 ENST00000564121.1
RP11-521O16.2
RP11-521O16.2
chrX_-_77225135 0.06 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr11_+_5474638 0.06 ENST00000341449.2
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr11_-_47447970 0.06 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chrX_+_37208540 0.06 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr11_+_65769550 0.06 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr19_+_55014085 0.06 ENST00000351841.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr17_-_3571934 0.06 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr6_+_30585486 0.06 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr12_-_53715328 0.06 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
AAAS
achalasia, adrenocortical insufficiency, alacrimia
chr19_+_55014013 0.06 ENST00000301202.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr15_+_79166065 0.05 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr11_-_62572901 0.05 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1
nuclear RNA export factor 1
chr6_+_27114861 0.05 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr1_+_109255279 0.05 ENST00000370017.3
FNDC7
fibronectin type III domain containing 7
chr20_-_48770244 0.05 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.6 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.8 GO:0001554 luteolysis(GO:0001554)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.5 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.3 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.2 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex