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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HMX1

Z-value: 0.80

Motif logo

Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.5 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg19_v2_chr4_-_8873531_88735430.048.5e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_49259643 1.89 ENST00000309739.5
Rho family GTPase 1
chr12_+_57482665 1.29 ENST00000300131.3
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr5_-_81046904 1.20 ENST00000515395.1
single-stranded DNA binding protein 2
chr12_+_57482877 1.20 ENST00000342556.6
ENST00000357680.4
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr5_-_81046841 1.15 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
single-stranded DNA binding protein 2
chr4_-_186733363 1.14 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr11_+_59522900 1.12 ENST00000529177.1
syntaxin 3
chr19_+_1407733 1.09 ENST00000592453.1
DAZ associated protein 1
chr14_+_63671577 0.96 ENST00000555125.1
ras homolog family member J
chr11_+_59522837 0.95 ENST00000437946.2
syntaxin 3
chr16_+_88872176 0.92 ENST00000569140.1
chromatin licensing and DNA replication factor 1
chr9_-_130617029 0.71 ENST00000373203.4
endoglin
chr1_-_41328018 0.70 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr9_-_130616915 0.69 ENST00000344849.3
endoglin
chr2_+_106682135 0.68 ENST00000437659.1
chromosome 2 open reading frame 40
chr2_+_106682103 0.66 ENST00000238044.3
chromosome 2 open reading frame 40
chr7_-_156685841 0.66 ENST00000354505.4
ENST00000540390.1
limb development membrane protein 1
chr12_+_53440753 0.63 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr9_+_82186682 0.60 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_45935663 0.60 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
zinc finger and BTB domain containing 7C
chr17_+_66509019 0.59 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr11_-_128392085 0.57 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr15_+_89402148 0.57 ENST00000560601.1
aggrecan
chr14_+_56585048 0.56 ENST00000267460.4
pellino E3 ubiquitin protein ligase family member 2
chr11_-_64815333 0.56 ENST00000533842.1
ENST00000532802.1
ENST00000530139.1
ENST00000526516.1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr3_+_5020801 0.54 ENST00000256495.3
basic helix-loop-helix family, member e40
chr1_-_27286897 0.51 ENST00000320567.5
chromosome 1 open reading frame 172
chr21_-_40032581 0.50 ENST00000398919.2
v-ets avian erythroblastosis virus E26 oncogene homolog
chr9_+_82186872 0.49 ENST00000376544.3
ENST00000376520.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_+_53123314 0.48 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
long intergenic non-protein coding RNA 1155
chr5_+_139027877 0.46 ENST00000302517.3
CXXC finger protein 5
chr3_+_20081515 0.45 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr4_+_86396321 0.43 ENST00000503995.1
Rho GTPase activating protein 24
chr17_-_6947225 0.43 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr3_-_128294929 0.42 ENST00000356020.2
chromosome 3 open reading frame 27
chr17_+_79989937 0.42 ENST00000580965.1
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_-_85930246 0.42 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr13_+_25254545 0.39 ENST00000218548.6
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr22_-_18923655 0.38 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr9_-_140082983 0.38 ENST00000323927.2
anaphase promoting complex subunit 2
chr3_+_101546827 0.37 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr3_+_127391769 0.37 ENST00000393363.3
ENST00000232744.8
ENST00000453791.2
ankyrin repeat and BTB (POZ) domain containing 1
chr1_-_167059830 0.37 ENST00000367868.3
glycoprotein A33 (transmembrane)
chr12_+_53400176 0.37 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
eukaryotic translation initiation factor 4B
chr19_-_46526304 0.36 ENST00000008938.4
peptidoglycan recognition protein 1
chr17_+_79989500 0.36 ENST00000306897.4
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr3_+_151986709 0.35 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr4_-_80993717 0.35 ENST00000307333.7
anthrax toxin receptor 2
chr17_-_7165662 0.34 ENST00000571881.2
ENST00000360325.7
claudin 7
chrX_+_13587712 0.34 ENST00000361306.1
ENST00000380602.3
EGF-like-domain, multiple 6
chr20_-_35374456 0.34 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG family member 3
chr3_+_57994127 0.32 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
filamin B, beta
chr17_-_74533734 0.32 ENST00000589342.1
cytoglobin
chr5_+_156693091 0.31 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr1_-_53387386 0.31 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
enoyl CoA hydratase domain containing 2
chr17_+_79990058 0.31 ENST00000584341.1
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr10_-_99531709 0.30 ENST00000266066.3
secreted frizzled-related protein 5
chr9_-_131644202 0.30 ENST00000320665.6
ENST00000436267.2
cysteine conjugate-beta lyase, cytoplasmic
chr1_-_154946825 0.30 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC (Src homology 2 domain containing) transforming protein 1
chr17_-_62097904 0.29 ENST00000583366.1
intercellular adhesion molecule 2
chr17_-_73874654 0.29 ENST00000254816.2
tripartite motif containing 47
chr22_-_37640456 0.29 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_-_11430221 0.29 ENST00000514690.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr19_-_14316980 0.28 ENST00000361434.3
ENST00000340736.6
latrophilin 1
chrX_+_70443050 0.28 ENST00000361726.6
gap junction protein, beta 1, 32kDa
chr1_-_46598371 0.28 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_-_32229523 0.27 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
brain-specific angiogenesis inhibitor 2
chr18_+_11981427 0.27 ENST00000269159.3
inositol(myo)-1(or 4)-monophosphatase 2
chr12_+_53399942 0.27 ENST00000262056.9
eukaryotic translation initiation factor 4B
chr19_-_1401486 0.27 ENST00000252288.2
ENST00000447102.3
guanidinoacetate N-methyltransferase
chr7_-_156685890 0.27 ENST00000353442.5
limb development membrane protein 1
chr8_+_145691411 0.27 ENST00000301332.2
kinesin family member C2
chr4_+_86396265 0.26 ENST00000395184.1
Rho GTPase activating protein 24
chr13_+_25254693 0.26 ENST00000381946.3
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr2_+_204801471 0.26 ENST00000316386.6
ENST00000435193.1
inducible T-cell co-stimulator
chr5_+_156693159 0.26 ENST00000347377.6
cytoplasmic FMR1 interacting protein 2
chr1_-_46598284 0.26 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_-_32229934 0.26 ENST00000398542.1
brain-specific angiogenesis inhibitor 2
chr3_+_49711777 0.26 ENST00000442186.1
ENST00000438011.1
ENST00000457042.1
acylaminoacyl-peptide hydrolase
chr8_-_105479270 0.25 ENST00000521573.2
ENST00000351513.2
dihydropyrimidinase
chr7_+_155250824 0.25 ENST00000297375.4
engrailed homeobox 2
chr22_+_47070490 0.25 ENST00000408031.1
GRAM domain containing 4
chr7_-_132261253 0.25 ENST00000321063.4
plexin A4
chr1_+_39546988 0.24 ENST00000484793.1
microtubule-actin crosslinking factor 1
chr1_-_33168336 0.24 ENST00000373484.3
syncoilin, intermediate filament protein
chr22_-_38349552 0.23 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
chromosome 22 open reading frame 23
chr17_-_15244894 0.23 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr12_-_55378452 0.23 ENST00000449076.1
thymocyte expressed, positive selection associated 1
chr19_-_10697895 0.23 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr15_+_24920541 0.23 ENST00000329468.2
nuclear pore associated protein 1
chr5_-_81046922 0.23 ENST00000514493.1
ENST00000320672.4
single-stranded DNA binding protein 2
chr17_-_62097927 0.22 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr6_+_41606176 0.22 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr17_+_77751931 0.22 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr9_-_131644306 0.22 ENST00000302586.3
cysteine conjugate-beta lyase, cytoplasmic
chr14_-_25103388 0.22 ENST00000526004.1
ENST00000415355.3
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr7_+_31009148 0.22 ENST00000409904.3
ENST00000409316.1
growth hormone releasing hormone receptor
chr9_+_10613163 0.22 ENST00000429581.2
RP11-87N24.2
chr21_-_40685536 0.21 ENST00000341322.4
bromodomain and WD repeat domain containing 1
chr14_-_25103472 0.21 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr14_+_63671105 0.21 ENST00000316754.3
ras homolog family member J
chr2_-_27545921 0.21 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MpV17 mitochondrial inner membrane protein
chr7_-_37488834 0.21 ENST00000310758.4
engulfment and cell motility 1
chr3_+_39093481 0.21 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
WD repeat domain 48
chr11_-_417388 0.21 ENST00000332725.3
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr12_+_41831485 0.21 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr3_+_69788576 0.21 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr9_+_131644398 0.20 ENST00000372599.3
leucine rich repeat containing 8 family, member A
chr20_+_30640004 0.20 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
hemopoietic cell kinase
chr3_-_107941209 0.20 ENST00000492106.1
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_-_27712583 0.20 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
intraflagellar transport 172 homolog (Chlamydomonas)
chr1_+_39547082 0.20 ENST00000602421.1
microtubule-actin crosslinking factor 1
chr11_-_417308 0.20 ENST00000397632.3
ENST00000382520.2
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr1_-_51425902 0.20 ENST00000396153.2
Fas (TNFRSF6) associated factor 1
chr3_+_50192537 0.20 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_-_125775629 0.20 ENST00000383598.2
solute carrier family 41, member 3
chr3_+_50192499 0.19 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr20_+_30639991 0.19 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
hemopoietic cell kinase
chr2_-_27545431 0.19 ENST00000233545.2
MpV17 mitochondrial inner membrane protein
chr9_+_131644388 0.19 ENST00000372600.4
leucine rich repeat containing 8 family, member A
chr11_-_33743952 0.19 ENST00000534312.1
CD59 molecule, complement regulatory protein
chr12_+_81110684 0.19 ENST00000228644.3
myogenic factor 5
chr17_+_79679369 0.19 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_+_10091783 0.19 ENST00000324883.5
grainyhead-like 1 (Drosophila)
chr2_-_197457335 0.19 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr17_+_79679299 0.19 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr18_+_11981547 0.18 ENST00000588927.1
inositol(myo)-1(or 4)-monophosphatase 2
chr2_+_10091815 0.18 ENST00000324907.9
grainyhead-like 1 (Drosophila)
chr6_-_2245892 0.18 ENST00000380815.4
GDP-mannose 4,6-dehydratase
chr3_-_52864680 0.18 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr9_+_131644781 0.18 ENST00000259324.5
leucine rich repeat containing 8 family, member A
chrX_-_20284958 0.17 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr20_+_3451732 0.17 ENST00000446916.2
attractin
chr19_-_2308127 0.17 ENST00000404279.1
leucine rich repeat and Ig domain containing 3
chrX_+_110924346 0.17 ENST00000371979.3
ENST00000251943.4
ENST00000486353.1
ENST00000394780.3
ENST00000495283.1
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr5_-_172662303 0.16 ENST00000517440.1
ENST00000329198.4
NK2 homeobox 5
chr11_-_116968987 0.16 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr8_+_145438870 0.16 ENST00000527931.1
family with sequence similarity 203, member B
chr16_+_3062457 0.16 ENST00000445369.2
claudin 9
chr1_+_160336851 0.16 ENST00000302101.5
nescient helix loop helix 1
chr7_+_130131907 0.16 ENST00000223215.4
ENST00000437945.1
mesoderm specific transcript
chr4_-_141348999 0.16 ENST00000325617.5
calmegin
chr19_-_19006920 0.16 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr10_+_99258625 0.16 ENST00000370664.3
ubiquitin domain containing 1
chr19_+_41305330 0.16 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr4_-_141348789 0.15 ENST00000414773.1
calmegin
chr8_-_67525473 0.15 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr8_+_32406179 0.15 ENST00000405005.3
neuregulin 1
chr3_-_138553779 0.15 ENST00000461451.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr12_+_70132632 0.15 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr17_-_72709050 0.15 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300 molecule-like family member f
chr6_+_30131318 0.15 ENST00000376688.1
tripartite motif containing 15
chr9_-_130331297 0.15 ENST00000373312.3
family with sequence similarity 129, member B
chr10_+_126150369 0.15 ENST00000392757.4
ENST00000368842.5
ENST00000368839.1
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr22_+_38349670 0.15 ENST00000442738.2
ENST00000460648.1
ENST00000407936.1
ENST00000488684.1
ENST00000492213.1
ENST00000606538.1
ENST00000405557.1
polymerase (RNA) II (DNA directed) polypeptide F
chr19_-_10687907 0.14 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr10_-_135122603 0.14 ENST00000368563.2
tubulin, gamma complex associated protein 2
chr9_+_137967366 0.14 ENST00000252854.4
olfactomedin 1
chr3_-_88198965 0.14 ENST00000467332.1
ENST00000462901.1
CGG triplet repeat binding protein 1
chr1_-_51425772 0.14 ENST00000371778.4
Fas (TNFRSF6) associated factor 1
chr1_-_24194771 0.14 ENST00000374479.3
fucosidase, alpha-L- 1, tissue
chr9_-_116061476 0.14 ENST00000441031.3
ring finger protein 183
chr19_-_7939319 0.14 ENST00000539422.1
Protein FLJ22184
chr6_+_2246023 0.14 ENST00000530833.1
ENST00000525811.1
ENST00000534441.1
ENST00000533653.1
ENST00000534468.1
GMDS antisense RNA 1 (head to head)
chr6_-_8102714 0.14 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr5_+_141016969 0.14 ENST00000518856.1
RELT-like 2
chr1_-_207095212 0.14 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr14_+_23564700 0.13 ENST00000554203.1
chromosome 14 open reading frame 119
chr5_+_141016508 0.13 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELT-like 2
chr8_+_87878640 0.13 ENST00000518476.1
cyclic nucleotide binding domain containing 1
chr17_+_66508537 0.13 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_+_154947126 0.13 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr16_+_56623433 0.13 ENST00000570176.1
metallothionein 3
chr20_+_21284416 0.13 ENST00000539513.1
5'-3' exoribonuclease 2
chr1_-_109940550 0.13 ENST00000256637.6
sortilin 1
chr1_+_154947148 0.13 ENST00000368436.1
ENST00000308987.5
CDC28 protein kinase regulatory subunit 1B
chr6_+_2245982 0.13 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS antisense RNA 1 (head to head)
chr13_+_35516390 0.13 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr1_-_17338267 0.13 ENST00000326735.8
ATPase type 13A2
chr3_-_49066811 0.12 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chrX_-_153285251 0.12 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr11_-_110561721 0.12 ENST00000357139.3
Rho GTPase activating protein 20
chr3_-_18466787 0.12 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr19_+_41305612 0.12 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
egl-9 family hypoxia-inducible factor 2
chr12_-_7077125 0.12 ENST00000545555.2
prohibitin 2
chr20_+_21283941 0.12 ENST00000377191.3
ENST00000430571.2
5'-3' exoribonuclease 2
chr9_+_116263639 0.12 ENST00000343817.5
regulator of G-protein signaling 3
chr11_-_33744256 0.12 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59 molecule, complement regulatory protein
chr7_-_752577 0.12 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_-_188624 0.11 ENST00000399953.3
nitrogen permease regulator-like 3 (S. cerevisiae)
chr20_+_49348081 0.11 ENST00000371610.2
par-6 family cell polarity regulator beta
chr19_+_41305627 0.11 ENST00000593525.1
egl-9 family hypoxia-inducible factor 2
chr16_+_12995614 0.11 ENST00000423335.2
shisa family member 9
chr22_+_47158578 0.11 ENST00000355704.3
TBC1 domain family, member 22A
chr1_-_110052302 0.11 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chrX_+_135579238 0.11 ENST00000535601.1
ENST00000448450.1
ENST00000425695.1
HIV-1 Tat specific factor 1
chr5_+_10353780 0.11 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr9_-_116061145 0.11 ENST00000416588.2
ring finger protein 183
chr9_+_125273081 0.11 ENST00000335302.5
olfactory receptor, family 1, subfamily J, member 2
chr15_-_41166414 0.11 ENST00000220507.4
ras homolog family member V

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0001300 chronological cell aging(GO:0001300)
0.4 2.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 0.9 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.3 2.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.4 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.4 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.4 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 1.9 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.5 GO:0035948 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.1 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 1.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.2 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.6 GO:0030578 PML body organization(GO:0030578)
0.1 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0003285 atrioventricular node development(GO:0003162) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) septum secundum development(GO:0003285)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.2 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:2000374 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
0.0 0.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 1.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.5 1.4 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.6 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 1.4 GO:0005534 galactose binding(GO:0005534)
0.2 0.6 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 0.6 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 1.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 2.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 3.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes