Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for HMX2

Z-value: 0.57

Motif logo

logo of

Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 H6 family homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX2hg19_v2_chr10_+_124907638_1249076600.048.6e-01Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_7618413 1.28 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_148663729 0.85 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr10_-_7513904 0.83 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr8_-_101571933 0.78 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr9_+_27109392 0.77 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr8_-_101571964 0.75 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr1_+_109102652 0.73 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr8_-_93978357 0.71 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr4_-_138453606 0.71 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr2_-_201374781 0.70 ENST00000359878.3
ENST00000409157.1
KCTD18
potassium channel tetramerization domain containing 18
chr18_+_42260861 0.64 ENST00000282030.5
SETBP1
SET binding protein 1
chr5_+_95066823 0.63 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr21_+_31768348 0.63 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr8_-_93978346 0.57 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr8_-_93978333 0.56 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr2_-_151344172 0.55 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr6_-_51952418 0.54 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr3_+_16216137 0.53 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr17_+_56769924 0.51 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr5_+_156696362 0.51 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr17_-_29641084 0.51 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr1_+_201979645 0.51 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr15_+_67835517 0.49 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr8_-_93978309 0.47 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr1_+_15943995 0.47 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr15_+_55700741 0.45 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr7_+_77325738 0.45 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr1_+_186798073 0.45 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_-_13134045 0.45 ENST00000512044.2
DLC1
deleted in liver cancer 1
chrX_-_57164058 0.44 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr19_-_44384291 0.39 ENST00000324394.6
ZNF404
zinc finger protein 404
chr12_+_64798095 0.39 ENST00000332707.5
XPOT
exportin, tRNA
chr22_+_39795746 0.38 ENST00000216160.6
ENST00000331454.3
TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr2_-_169104651 0.38 ENST00000355999.4
STK39
serine threonine kinase 39
chr4_+_25915896 0.38 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr4_+_86749045 0.37 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr4_+_25915822 0.37 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr12_-_122985067 0.37 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr19_-_36001113 0.36 ENST00000434389.1
DMKN
dermokine
chr4_+_86748898 0.35 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr3_+_145782358 0.35 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr17_-_47755436 0.32 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr14_+_57857262 0.32 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr17_-_46671323 0.32 ENST00000239151.5
HOXB5
homeobox B5
chr10_-_120925054 0.32 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4
sideroflexin 4
chr1_+_62439037 0.31 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr12_-_10541575 0.30 ENST00000540818.1
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr12_+_25205568 0.29 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr9_-_111882195 0.29 ENST00000374586.3
TMEM245
transmembrane protein 245
chr10_+_94594351 0.29 ENST00000371552.4
EXOC6
exocyst complex component 6
chr7_+_75024903 0.29 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr6_+_12290586 0.28 ENST00000379375.5
EDN1
endothelin 1
chr15_+_41056255 0.28 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr3_+_111697843 0.28 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr4_-_48782259 0.27 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr5_+_156607829 0.27 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr2_-_99279928 0.26 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr5_+_61602055 0.26 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr6_+_151561085 0.26 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_213189168 0.26 ENST00000366962.3
ENST00000360506.2
ANGEL2
angel homolog 2 (Drosophila)
chr6_-_151773232 0.26 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr15_+_41056218 0.26 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr7_-_7680601 0.26 ENST00000396682.2
RPA3
replication protein A3, 14kDa
chr14_+_32798547 0.25 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_217804377 0.25 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chr19_-_3772209 0.25 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chr2_+_1417228 0.24 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr17_+_67498538 0.24 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_+_140227048 0.24 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr6_+_26124373 0.24 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr13_-_103426112 0.23 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr4_-_26492076 0.23 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chrX_-_153979315 0.23 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr15_-_50558223 0.23 ENST00000267845.3
HDC
histidine decarboxylase
chr10_-_126849588 0.22 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr13_+_27998681 0.22 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr6_+_64345698 0.21 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr13_-_103426081 0.21 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr9_-_21385396 0.21 ENST00000380206.2
IFNA2
interferon, alpha 2
chr15_-_55700522 0.20 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr7_+_5920429 0.20 ENST00000242104.5
OCM
oncomodulin
chr12_+_133614119 0.20 ENST00000327668.7
ZNF84
zinc finger protein 84
chr1_-_108231101 0.20 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr1_-_70820357 0.19 ENST00000370944.4
ENST00000262346.6
ANKRD13C
ankyrin repeat domain 13C
chr11_-_64684672 0.19 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr10_-_47239738 0.19 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr9_+_99690592 0.18 ENST00000354649.3
NUTM2G
NUT family member 2G
chr10_+_48189612 0.18 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr7_+_39125365 0.18 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr19_+_52772821 0.17 ENST00000439461.1
ZNF766
zinc finger protein 766
chr15_-_55700457 0.17 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr3_-_46249878 0.17 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr3_+_39424828 0.17 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chr9_+_27109133 0.17 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr12_+_25205446 0.17 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr14_+_32798462 0.17 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_131843377 0.16 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1
dolichyldiphosphatase 1
chr2_+_24272543 0.16 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr7_-_84569561 0.16 ENST00000439105.1
AC074183.4
AC074183.4
chr9_+_130026756 0.16 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr3_+_173116225 0.15 ENST00000457714.1
NLGN1
neuroligin 1
chr1_+_99127225 0.15 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr4_+_83956237 0.15 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr6_+_25754927 0.15 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr4_+_83956312 0.15 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr10_+_116697946 0.14 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chr2_-_55237484 0.14 ENST00000394609.2
RTN4
reticulon 4
chr1_-_21377383 0.14 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_51952367 0.14 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr5_-_43397184 0.14 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr8_-_37797621 0.14 ENST00000524298.1
ENST00000307599.4
GOT1L1
glutamic-oxaloacetic transaminase 1-like 1
chr2_+_109237717 0.13 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr14_+_31091511 0.13 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chr20_-_29978286 0.13 ENST00000376315.2
DEFB119
defensin, beta 119
chr3_-_114343039 0.13 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_11918988 0.13 ENST00000376468.3
NPPB
natriuretic peptide B
chr2_-_20251744 0.13 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr10_-_22292675 0.13 ENST00000376946.1
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr10_-_115613828 0.13 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr7_+_97736197 0.12 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr13_+_50570019 0.12 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr3_+_23847394 0.12 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr14_-_59950724 0.12 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr20_+_5986727 0.11 ENST00000378863.4
CRLS1
cardiolipin synthase 1
chr5_-_169725231 0.11 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_179280668 0.11 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr17_-_15469590 0.11 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr1_-_111174054 0.11 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr19_+_15852203 0.10 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr4_+_83821835 0.10 ENST00000302236.5
THAP9
THAP domain containing 9
chrX_+_133594168 0.10 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr22_+_42095497 0.10 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr20_+_5986756 0.10 ENST00000452938.1
CRLS1
cardiolipin synthase 1
chr19_+_54641444 0.10 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chrX_+_119737806 0.10 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr17_+_48823896 0.10 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr9_+_12693336 0.10 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr10_-_99205607 0.10 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr15_-_40074996 0.10 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr7_-_32529973 0.10 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_111334678 0.10 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr10_-_12238071 0.09 ENST00000491614.1
ENST00000537776.1
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr19_-_41985048 0.09 ENST00000599801.1
ENST00000595063.1
ENST00000598215.1
AC011526.1
AC011526.1
chr12_-_123450986 0.09 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr14_+_65381079 0.09 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr11_+_122753391 0.09 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr15_+_58702742 0.09 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr8_+_62737875 0.09 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
RP11-705O24.1
chr3_+_23847432 0.08 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr1_+_33546714 0.08 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr3_+_186560462 0.08 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr2_-_190044480 0.08 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr3_+_186560476 0.08 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr19_+_52772832 0.08 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr4_+_90823130 0.08 ENST00000508372.1
MMRN1
multimerin 1
chr4_-_138453559 0.08 ENST00000511115.1
PCDH18
protocadherin 18
chr6_-_9977801 0.08 ENST00000316020.6
ENST00000491508.1
OFCC1
orofacial cleft 1 candidate 1
chr19_+_40877583 0.08 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr14_-_106494587 0.08 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr16_-_67517716 0.08 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr19_+_12175504 0.07 ENST00000439326.3
ZNF844
zinc finger protein 844
chr5_+_154393260 0.07 ENST00000435029.4
KIF4B
kinesin family member 4B
chr9_+_130159409 0.07 ENST00000373371.3
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr8_-_67974552 0.07 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr2_-_152590982 0.07 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr9_-_97090926 0.07 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUTM2F
NUT family member 2F
chr6_+_26204825 0.07 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr10_-_121296045 0.06 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr17_+_54230819 0.06 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr1_-_110933611 0.06 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr14_+_27342334 0.06 ENST00000548170.1
ENST00000552926.1
RP11-384J4.1
RP11-384J4.1
chr9_-_95055956 0.06 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr7_-_155604967 0.06 ENST00000297261.2
SHH
sonic hedgehog
chr1_-_11865351 0.06 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_70820451 0.06 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr17_-_73663245 0.06 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr10_-_22292613 0.05 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr6_-_2751146 0.05 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr2_+_118572226 0.05 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr19_-_14889349 0.05 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr1_-_110933663 0.05 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr5_-_22853429 0.05 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr19_+_58144529 0.05 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr1_+_239882842 0.05 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr18_+_76829441 0.04 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr10_+_81462983 0.04 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUTM2B
NUT family member 2B
chr12_+_26164645 0.04 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_+_112408768 0.04 ENST00000368656.2
ENST00000604268.1
FAM229B
family with sequence similarity 229, member B
chr4_+_166248775 0.04 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr19_+_41281416 0.04 ENST00000597140.1
MIA
melanoma inhibitory activity
chr2_+_27070964 0.04 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr17_-_295730 0.04 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr20_-_16554078 0.04 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
KIF16B
kinesin family member 16B
chr2_-_160654745 0.04 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr11_-_118972575 0.03 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_+_23851928 0.03 ENST00000467766.1
ENST00000424381.1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr2_+_211342432 0.03 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr12_+_128399917 0.02 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr10_+_13203543 0.02 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chr17_-_29641104 0.02 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 0.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.5 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.3 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.5 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0048680 neuronal action potential propagation(GO:0019227) positive regulation of axon regeneration(GO:0048680) action potential propagation(GO:0098870)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:2000172 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.7 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis