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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HMX3

Z-value: 0.87

Motif logo

Transcription factors associated with HMX3

Gene Symbol Gene ID Gene Info
ENSG00000188620.9 H6 family homeobox 3

Activity profile of HMX3 motif

Sorted Z-values of HMX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_101439242 2.96 ENST00000296420.4
endomucin
chr4_+_156588249 2.79 ENST00000393832.3
guanylate cyclase 1, soluble, alpha 3
chr4_-_90756769 2.48 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_101439148 2.32 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
endomucin
chr12_-_10022735 2.17 ENST00000228438.2
C-type lectin domain family 2, member B
chr17_+_39394250 2.07 ENST00000254072.6
keratin associated protein 9-8
chr4_-_90759440 2.00 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr2_+_173686303 1.81 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr9_+_71986182 1.77 ENST00000303068.7
family with sequence similarity 189, member A2
chr8_-_93029865 1.73 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_41985048 1.72 ENST00000599801.1
ENST00000595063.1
ENST00000598215.1
AC011526.1
chr4_-_90757364 1.60 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_159080806 1.55 ENST00000590648.1
family with sequence similarity 198, member B
chr12_+_51318513 1.50 ENST00000332160.4
methyltransferase like 7A
chr2_+_89890533 1.49 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr10_-_7513904 1.46 ENST00000420395.1
RP5-1031D4.2
chr6_-_76203454 1.41 ENST00000237172.7
filamin A interacting protein 1
chrX_-_154033661 1.40 ENST00000393531.1
membrane protein, palmitoylated 1, 55kDa
chr1_-_110933611 1.20 ENST00000472422.2
ENST00000437429.2
solute carrier family 16, member 4
chr2_-_191115229 1.18 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr21_+_17909594 1.15 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr5_-_55412774 1.14 ENST00000434982.2
ankyrin repeat domain 55
chr10_-_126849588 1.11 ENST00000411419.2
C-terminal binding protein 2
chr7_+_150413645 1.11 ENST00000307194.5
GTPase, IMAP family member 1
chr5_+_140227048 1.11 ENST00000532602.1
protocadherin alpha 9
chr1_+_109102652 1.08 ENST00000370035.3
ENST00000405454.1
family with sequence similarity 102, member B
chr6_-_84419101 1.08 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr14_-_105420241 1.07 ENST00000557457.1
AHNAK nucleoprotein 2
chr9_+_99690592 1.07 ENST00000354649.3
NUT family member 2G
chr16_+_20775358 1.03 ENST00000440284.2
acyl-CoA synthetase medium-chain family member 3
chr2_-_136873735 1.01 ENST00000409817.1
chemokine (C-X-C motif) receptor 4
chr8_+_97506033 1.00 ENST00000518385.1
syndecan 2
chr5_+_112849373 0.98 ENST00000161863.4
ENST00000515883.1
YTH domain containing 2
chr6_-_52859046 0.97 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr5_+_121647386 0.97 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
synuclein, alpha interacting protein
chr4_-_104021009 0.97 ENST00000509245.1
ENST00000296424.4
3-hydroxybutyrate dehydrogenase, type 2
chr14_+_64680854 0.96 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr4_+_90823130 0.94 ENST00000508372.1
multimerin 1
chr15_+_25200074 0.92 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
small nuclear ribonucleoprotein polypeptide N
chr11_+_62104897 0.91 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
asparaginase like 1
chr17_-_295730 0.90 ENST00000329099.4
family with sequence similarity 101, member B
chr11_+_7618413 0.89 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_76540386 0.89 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr6_+_168196210 0.87 ENST00000597278.1
Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793
chr22_-_29107919 0.87 ENST00000434810.1
ENST00000456369.1
checkpoint kinase 2
chr1_-_21377447 0.86 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_110933663 0.85 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chrX_+_13671225 0.84 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr17_+_32597232 0.83 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
chemokine (C-C motif) ligand 7
chr12_-_27167233 0.81 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
transmembrane 7 superfamily member 3
chr12_-_6055398 0.81 ENST00000327087.8
ENST00000356134.5
ENST00000546188.1
anoctamin 2
chr5_-_94417339 0.80 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr8_-_17555164 0.80 ENST00000297488.6
microtubule associated tumor suppressor 1
chr17_+_67498538 0.79 ENST00000589647.1
mitogen-activated protein kinase kinase 6
chr5_+_95066823 0.79 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr11_+_5410607 0.78 ENST00000328611.3
olfactory receptor, family 51, subfamily M, member 1
chr13_-_110438914 0.78 ENST00000375856.3
insulin receptor substrate 2
chr11_-_101000445 0.78 ENST00000534013.1
progesterone receptor
chr10_-_101945771 0.77 ENST00000370408.2
ENST00000407654.3
ER lipid raft associated 1
chr3_+_124223586 0.76 ENST00000393496.1
kalirin, RhoGEF kinase
chr21_+_17791648 0.76 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr9_-_5833027 0.75 ENST00000339450.5
endoplasmic reticulum metallopeptidase 1
chr12_-_10959892 0.75 ENST00000240615.2
taste receptor, type 2, member 8
chr8_-_19459993 0.75 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr4_-_138453606 0.75 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr19_+_45844032 0.74 ENST00000589837.1
kinesin light chain 3
chr7_+_63361201 0.74 ENST00000450544.1
RP11-340I6.8
chr3_+_51895621 0.74 ENST00000333127.3
IQ motif containing F2
chr17_+_56769924 0.74 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51 paralog C
chr6_+_28249299 0.73 ENST00000405948.2
piggyBac transposable element derived 1
chr8_+_62747349 0.73 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
chr6_+_28249332 0.72 ENST00000259883.3
piggyBac transposable element derived 1
chr21_+_17791838 0.72 ENST00000453910.1
long intergenic non-protein coding RNA 478
chr3_-_165555200 0.69 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr2_+_179149636 0.69 ENST00000409631.1
oxysterol binding protein-like 6
chr4_-_48782259 0.68 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr4_-_110624564 0.68 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
caspase 6, apoptosis-related cysteine peptidase
chr6_+_72922590 0.67 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr2_+_108994633 0.66 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr8_+_134125727 0.66 ENST00000521107.1
thyroglobulin
chr2_-_68290106 0.65 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D nuclear receptor corepressor
chr11_-_102576537 0.65 ENST00000260229.4
matrix metallopeptidase 27
chr6_+_73076432 0.64 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr10_-_95241951 0.64 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr3_+_16216137 0.63 ENST00000339732.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr5_+_175288631 0.63 ENST00000509837.1
complexin 2
chr1_-_86861660 0.63 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr22_+_29702996 0.63 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
growth arrest-specific 2 like 1
chr6_+_116691001 0.62 ENST00000537543.1
dermatan sulfate epimerase
chr2_+_1417228 0.62 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
thyroid peroxidase
chr10_+_81462983 0.61 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUT family member 2B
chr2_-_99279928 0.61 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_+_109237717 0.61 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr5_-_9630463 0.61 ENST00000382492.2
taste receptor, type 2, member 1
chr7_-_72992865 0.60 ENST00000452475.1
transducin (beta)-like 2
chrX_+_55744228 0.60 ENST00000262850.7
Ras-related GTP binding B
chr1_-_21377383 0.59 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr11_+_101983176 0.59 ENST00000524575.1
Yes-associated protein 1
chr12_-_10978957 0.59 ENST00000240619.2
taste receptor, type 2, member 10
chr7_+_150382781 0.59 ENST00000223293.5
ENST00000474605.1
GTPase, IMAP family member 2
chr12_-_25055177 0.58 ENST00000538118.1
branched chain amino-acid transaminase 1, cytosolic
chr14_-_74551096 0.58 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr11_-_124981475 0.58 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr15_+_65843130 0.57 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr7_-_121784285 0.57 ENST00000417368.2
aminoadipate-semialdehyde synthase
chr6_+_148663729 0.56 ENST00000367467.3
SAM and SH3 domain containing 1
chr14_+_31046959 0.56 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr6_+_72922505 0.56 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr7_+_138943265 0.55 ENST00000483726.1
ubinuclein 2
chr1_-_174992544 0.55 ENST00000476371.1
mitochondrial ribosomal protein S14
chr2_-_89247338 0.55 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr17_+_66521936 0.55 ENST00000592800.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr16_-_66584059 0.55 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr21_-_31869451 0.54 ENST00000334058.2
keratin associated protein 19-4
chr7_+_80275953 0.54 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr12_+_101988627 0.54 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr5_-_93447333 0.53 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr6_+_32605195 0.53 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chrX_-_154033793 0.52 ENST00000369534.3
ENST00000413259.3
membrane protein, palmitoylated 1, 55kDa
chr8_-_93978309 0.52 ENST00000517858.1
ENST00000378861.5
triple QxxK/R motif containing
chr17_-_76870222 0.52 ENST00000585421.1
TIMP metallopeptidase inhibitor 2
chr8_-_17752996 0.51 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chrX_+_55744166 0.51 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr2_+_28618532 0.51 ENST00000545753.1
FOS-like antigen 2
chr10_+_101491968 0.51 ENST00000370476.5
ENST00000370472.4
cutC copper transporter
chr9_+_21409146 0.51 ENST00000380205.1
interferon, alpha 8
chr6_-_158589259 0.51 ENST00000367101.1
ENST00000367104.3
ENST00000367102.2
serine active site containing 1
chr1_+_196788887 0.50 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr17_-_76870126 0.50 ENST00000586057.1
TIMP metallopeptidase inhibitor 2
chr5_-_42812143 0.50 ENST00000514985.1
selenoprotein P, plasma, 1
chr16_-_90096309 0.49 ENST00000408886.2
chromosome 16 open reading frame 3
chr1_-_45140074 0.49 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
transmembrane protein 53
chr2_+_108994466 0.49 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr4_+_83956312 0.49 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr11_+_92085262 0.49 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr5_-_94417314 0.49 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr12_+_29376673 0.48 ENST00000547116.1
fatty acyl CoA reductase 2
chr11_+_34643600 0.48 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr19_+_58193388 0.48 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
Uncharacterized protein
chr7_+_107224364 0.47 ENST00000491150.1
B-cell receptor-associated protein 29
chr2_+_24272543 0.47 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr4_+_83956237 0.47 ENST00000264389.2
COP9 signalosome subunit 4
chr21_-_40033618 0.47 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chrX_+_36053908 0.47 ENST00000378660.2
calponin homology domain containing 2
chr8_-_17752912 0.46 ENST00000398054.1
ENST00000381840.2
fibrinogen-like 1
chr3_-_105588231 0.46 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_+_58702742 0.46 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr14_-_23426322 0.46 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr8_-_93978333 0.46 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
triple QxxK/R motif containing
chr8_-_93978346 0.46 ENST00000523580.1
triple QxxK/R motif containing
chr12_+_29376592 0.45 ENST00000182377.4
fatty acyl CoA reductase 2
chr4_-_110723194 0.45 ENST00000394635.3
complement factor I
chr1_-_150978953 0.45 ENST00000493834.2
family with sequence similarity 63, member A
chr12_+_29302119 0.45 ENST00000536681.3
fatty acyl CoA reductase 2
chr9_+_27109392 0.45 ENST00000406359.4
TEK tyrosine kinase, endothelial
chrX_-_57164058 0.45 ENST00000374906.3
spindlin family, member 2A
chr1_+_43291220 0.44 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr17_-_21156578 0.44 ENST00000399011.2
ENST00000468196.1
chromosome 17 open reading frame 103
chr6_+_27791862 0.44 ENST00000355057.1
histone cluster 1, H4j
chr4_-_110723134 0.44 ENST00000510800.1
ENST00000512148.1
complement factor I
chr10_+_13203543 0.43 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chrX_-_16730984 0.43 ENST00000380241.3
CTP synthase 2
chr17_+_56315787 0.43 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr14_+_96000930 0.43 ENST00000331334.4
glutaredoxin 5
chr8_-_121457332 0.43 ENST00000518918.1
mitochondrial ribosomal protein L13
chr16_+_20775024 0.43 ENST00000289416.5
acyl-CoA synthetase medium-chain family member 3
chr19_+_15852203 0.43 ENST00000305892.1
olfactory receptor, family 10, subfamily H, member 3
chrX_-_16730688 0.42 ENST00000359276.4
CTP synthase 2
chr7_+_101460882 0.42 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1
chr10_-_91011548 0.42 ENST00000456827.1
lipase A, lysosomal acid, cholesterol esterase
chr17_-_79105734 0.42 ENST00000417379.1
apoptosis-associated tyrosine kinase
chr6_+_32709119 0.42 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr12_+_52695617 0.42 ENST00000293525.5
keratin 86
chr12_+_125549925 0.41 ENST00000316519.6
acetoacetyl-CoA synthetase
chr1_+_367640 0.41 ENST00000426406.1
olfactory receptor, family 4, subfamily F, member 29
chr3_-_114343039 0.41 ENST00000481632.1
zinc finger and BTB domain containing 20
chr12_+_58087901 0.41 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr9_+_130911770 0.41 ENST00000372998.1
lipocalin 2
chr12_+_101988774 0.40 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr2_+_90121477 0.40 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr14_+_23012122 0.40 ENST00000390534.1
T cell receptor alpha joining 3
chr20_-_29978286 0.40 ENST00000376315.2
defensin, beta 119
chr6_-_35656685 0.40 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr19_+_10222189 0.40 ENST00000321826.4
purinergic receptor P2Y, G-protein coupled, 11
chr11_-_31531121 0.40 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_+_13842559 0.40 ENST00000586600.1
coiled-coil domain containing 130
chr16_+_33204156 0.40 ENST00000398667.4
TP53 target 3C
chr6_-_116575226 0.40 ENST00000420283.1
TSPY-like 4
chr19_+_1041212 0.39 ENST00000433129.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr11_+_57308979 0.39 ENST00000457912.1
smoothelin-like 1
chr14_+_22433675 0.39 ENST00000390442.3
T cell receptor alpha variable 12-3
chr5_-_176433350 0.38 ENST00000377227.4
ENST00000377219.2
ubiquitin interaction motif containing 1
chr1_-_35658736 0.38 ENST00000357214.5
splicing factor proline/glutamine-rich
chr10_-_18948156 0.38 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr5_+_140220769 0.38 ENST00000531613.1
ENST00000378123.3
protocadherin alpha 8
chrX_+_47444613 0.37 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr2_-_89292422 0.37 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr19_-_36001113 0.37 ENST00000434389.1
dermokine
chr16_-_19897455 0.37 ENST00000568214.1
ENST00000569479.1
G protein-coupled receptor, family C, group 5, member B
chr15_-_55700457 0.36 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.5 2.8 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3 2.1 GO:0006574 valine catabolic process(GO:0006574)
0.3 0.9 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 0.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 0.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 1.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.8 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 2.0 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.8 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.8 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 2.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.8 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.8 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.9 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 1.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.7 GO:0015705 iodide transport(GO:0015705)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.4 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 2.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.3 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.4 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 1.8 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.9 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.5 GO:0098870 neuronal action potential propagation(GO:0019227) positive regulation of axon regeneration(GO:0048680) action potential propagation(GO:0098870)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.0 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.9 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.3 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 1.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0051552 coumarin metabolic process(GO:0009804) flavone metabolic process(GO:0051552)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.5 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 3.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.5 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.6 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:1904430 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.3 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 2.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.0 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 1.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 2.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 0.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.3 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 0.8 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 1.9 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 1.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 2.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0070404 NADH binding(GO:0070404)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.2 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 7.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+