Project
Inflammatory response time course, HUVEC (Wada et al., 2009)
Navigation
Downloads
Results for HNF4G
Z-value: 1.25
Motif logo
Transcription factors associated with HNF4G
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4G | hg19_v2_chr8_+_76452097_76452126 | 0.02 | 9.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_95009837 Show fit | 8.20 |
ENST00000551457.1
|
transmembrane and coiled-coil domain family 3 |
|
| chr1_+_78511586 Show fit | 4.15 |
ENST00000370759.3
|
GIPC PDZ domain containing family, member 2 |
|
| chr17_+_68165657 Show fit | 3.81 |
ENST00000243457.3
|
potassium inwardly-rectifying channel, subfamily J, member 2 |
|
| chr1_+_164528866 Show fit | 3.80 |
ENST00000420696.2
|
pre-B-cell leukemia homeobox 1 |
|
| chr4_+_42399856 Show fit | 3.34 |
ENST00000319234.4
|
shisa family member 3 |
|
| chr11_-_118134997 Show fit | 3.06 |
ENST00000278937.2
|
myelin protein zero-like 2 |
|
| chr20_+_42574317 Show fit | 2.77 |
ENST00000358131.5
|
TOX high mobility group box family member 2 |
|
| chr2_+_12857043 Show fit | 2.73 |
ENST00000381465.2
|
tribbles pseudokinase 2 |
|
| chrX_+_138612889 Show fit | 2.73 |
ENST00000218099.2
ENST00000394090.2 |
coagulation factor IX |
|
| chr1_-_211752073 Show fit | 2.55 |
ENST00000367001.4
|
solute carrier family 30 (zinc transporter), member 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF4G
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 5.1 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.1 | 4.7 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.7 | 4.6 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.0 | 3.8 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.1 | 3.8 | GO:0008206 | bile acid metabolic process(GO:0008206) |
| 0.1 | 3.7 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.4 | 3.5 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 3.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.3 | 2.9 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.5 | 2.7 | GO:0045074 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.3 | 4.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 4.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 4.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 4.0 | GO:0044217 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.1 | 3.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 3.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.8 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 2.7 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.2 | 3.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 3.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 3.6 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 3.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 3.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 3.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.4 | 2.9 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 2.9 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 2.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.8 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 3.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 3.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 2.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 2.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 2.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 1.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.4 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 4.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 4.2 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 3.6 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 3.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 2.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 2.5 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 2.4 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 2.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |