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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXA1

Z-value: 0.61

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
HOXA1
ENSG00000105991.7 homeobox A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg19_v2_chr7_-_27135591_27135658-0.154.6e-01Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_42276574 1.14 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr17_-_42277203 0.83 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr22_-_30866564 0.73 ENST00000435069.1
ENST00000415957.2
ENST00000540910.1
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr6_+_80129989 0.55 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr6_+_32006042 0.55 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr6_-_31651817 0.50 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_+_65215604 0.47 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr20_-_30458491 0.46 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr6_+_32006159 0.45 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr12_-_96794143 0.41 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr14_+_21498666 0.40 ENST00000481535.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr2_-_4021643 0.37 ENST00000454455.1
AC107070.1
AC107070.1
chr10_-_65028817 0.36 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr12_-_52911718 0.36 ENST00000548409.1
KRT5
keratin 5
chr12_+_10658489 0.35 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr17_+_61554413 0.34 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
ACE
angiotensin I converting enzyme
chr7_-_100808394 0.34 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr5_+_133861339 0.32 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr7_-_100808843 0.30 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr2_-_71062938 0.30 ENST00000410009.3
CD207
CD207 molecule, langerin
chr10_-_65028938 0.30 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr19_-_51192661 0.30 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr16_+_28303804 0.30 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr11_-_2162162 0.29 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_-_42927251 0.28 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr5_-_20575959 0.28 ENST00000507958.1
CDH18
cadherin 18, type 2
chr12_-_85306562 0.27 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr5_+_159656437 0.27 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr11_+_5509915 0.27 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr7_-_44180884 0.27 ENST00000458240.1
ENST00000223364.3
MYL7
myosin, light chain 7, regulatory
chr2_+_162016827 0.26 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr12_+_12878829 0.25 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr5_+_36152179 0.24 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_89623194 0.24 ENST00000445946.3
KLLN
killin, p53-regulated DNA replication inhibitor
chr8_+_22132847 0.24 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr2_-_154335300 0.24 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_+_2005425 0.24 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr17_+_61571746 0.23 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr12_-_95510743 0.23 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_+_23637763 0.23 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr9_-_97402413 0.22 ENST00000414122.1
FBP1
fructose-1,6-bisphosphatase 1
chr10_-_98945515 0.22 ENST00000371070.4
SLIT1
slit homolog 1 (Drosophila)
chr1_-_13673511 0.22 ENST00000344998.3
ENST00000334600.6
PRAMEF14
PRAME family member 14
chr11_-_126870655 0.21 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr2_+_162016804 0.21 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr2_+_162016916 0.21 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr3_+_196366616 0.21 ENST00000426755.1
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr17_-_27278445 0.20 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr7_+_104654623 0.20 ENST00000311117.3
ENST00000334877.4
ENST00000257745.4
ENST00000334914.7
ENST00000478990.1
ENST00000495267.1
ENST00000476671.1
KMT2E
lysine (K)-specific methyltransferase 2E
chr2_+_161993465 0.20 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr20_+_52105495 0.20 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr19_-_38746979 0.20 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr8_-_27115931 0.19 ENST00000523048.1
STMN4
stathmin-like 4
chr8_+_22132810 0.19 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr9_-_130679257 0.19 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr19_+_5681011 0.18 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chrX_+_130192318 0.18 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr1_-_92351769 0.18 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr3_-_150920979 0.18 ENST00000309180.5
ENST00000480322.1
GPR171
G protein-coupled receptor 171
chr2_-_75788038 0.18 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr20_+_46130619 0.18 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr3_+_98250743 0.17 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr8_+_98788003 0.17 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr6_-_41122063 0.17 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
TREML1
triggering receptor expressed on myeloid cells-like 1
chr19_-_40732594 0.17 ENST00000430325.2
ENST00000433940.1
CNTD2
cyclin N-terminal domain containing 2
chr19_+_13875316 0.16 ENST00000319545.8
ENST00000593245.1
ENST00000040663.6
MRI1
methylthioribose-1-phosphate isomerase 1
chr21_-_46340884 0.16 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_104034827 0.16 ENST00000393158.2
PDGFD
platelet derived growth factor D
chr12_-_96794330 0.16 ENST00000261211.3
CDK17
cyclin-dependent kinase 17
chr17_-_3499125 0.16 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr9_-_123676827 0.16 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr7_+_139529040 0.16 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr20_+_30467600 0.16 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr1_-_13452656 0.16 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr19_+_39916575 0.16 ENST00000601124.1
CTB-60E11.4
CTB-60E11.4
chr11_-_2193025 0.16 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase
chr7_+_79765071 0.16 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chrX_-_63005405 0.16 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_161993412 0.16 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr2_-_70189397 0.15 ENST00000320256.4
ASPRV1
aspartic peptidase, retroviral-like 1
chr8_+_1993173 0.15 ENST00000523438.1
MYOM2
myomesin 2
chr3_+_196366555 0.15 ENST00000328557.4
NRROS
negative regulator of reactive oxygen species
chr8_+_1993152 0.15 ENST00000262113.4
MYOM2
myomesin 2
chr3_+_48264816 0.15 ENST00000296435.2
ENST00000576243.1
CAMP
cathelicidin antimicrobial peptide
chr7_-_120497178 0.15 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr16_-_49890016 0.15 ENST00000563137.2
ZNF423
zinc finger protein 423
chr3_+_38537960 0.15 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr6_-_154677900 0.15 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr11_-_104035088 0.15 ENST00000302251.5
PDGFD
platelet derived growth factor D
chr1_-_24469602 0.15 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr15_+_48009541 0.15 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chrX_-_57937067 0.14 ENST00000358697.4
ZXDA
zinc finger, X-linked, duplicated A
chr8_-_40755333 0.14 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr17_-_15502111 0.14 ENST00000354433.3
CDRT1
CMT1A duplicated region transcript 1
chr9_+_125281420 0.14 ENST00000340750.1
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr2_+_233897382 0.14 ENST00000233840.3
NEU2
sialidase 2 (cytosolic sialidase)
chr11_-_61647935 0.14 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr6_+_140175987 0.14 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr3_-_149093499 0.14 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr8_+_68864330 0.14 ENST00000288368.4
PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_139528952 0.14 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr6_+_90272027 0.14 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr2_-_47142884 0.14 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
MCFD2
multiple coagulation factor deficiency 2
chr15_-_74501310 0.13 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr5_+_108083517 0.13 ENST00000281092.4
ENST00000536402.1
FER
fer (fps/fes related) tyrosine kinase
chrX_-_52258669 0.13 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr17_+_39975544 0.13 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr5_-_693500 0.13 ENST00000360578.5
TPPP
tubulin polymerization promoting protein
chr5_+_36152163 0.13 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr17_+_39975455 0.13 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_+_367640 0.12 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr17_-_39041479 0.12 ENST00000167588.3
KRT20
keratin 20
chr14_+_65453432 0.12 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr4_+_113970772 0.12 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr12_-_51740463 0.12 ENST00000293636.1
CELA1
chymotrypsin-like elastase family, member 1
chr3_+_51863433 0.12 ENST00000444293.1
IQCF3
IQ motif containing F3
chrM_+_4431 0.12 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr13_+_102104952 0.12 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_44916098 0.12 ENST00000296125.4
TGM4
transglutaminase 4
chr7_-_101212244 0.12 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
LINC01007
long intergenic non-protein coding RNA 1007
chr1_-_151319710 0.11 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_-_45140074 0.11 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53
transmembrane protein 53
chrX_-_10645773 0.11 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr12_-_71533055 0.11 ENST00000552128.1
TSPAN8
tetraspanin 8
chr19_-_51141196 0.11 ENST00000338916.4
SYT3
synaptotagmin III
chr1_+_65730385 0.11 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_+_150040403 0.11 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr8_-_117043 0.11 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr10_-_33623310 0.11 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr3_-_129612394 0.11 ENST00000505616.1
ENST00000426664.2
TMCC1
transmembrane and coiled-coil domain family 1
chr1_-_205391178 0.11 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr1_+_3614591 0.11 ENST00000378290.4
TP73
tumor protein p73
chr16_-_28303360 0.11 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr5_-_133702761 0.11 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
CDKL3
cyclin-dependent kinase-like 3
chr10_+_89264625 0.11 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr20_+_30458431 0.11 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr12_+_8276495 0.11 ENST00000546339.1
CLEC4A
C-type lectin domain family 4, member A
chrX_-_25034065 0.10 ENST00000379044.4
ARX
aristaless related homeobox
chr1_+_159409512 0.10 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr16_+_66914264 0.10 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr22_-_19419205 0.10 ENST00000340170.4
ENST00000263208.5
HIRA
histone cell cycle regulator
chr8_+_86099884 0.10 ENST00000517476.1
ENST00000521429.1
E2F5
E2F transcription factor 5, p130-binding
chr6_+_50061315 0.10 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr13_+_30002846 0.10 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr4_-_145061788 0.09 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA
GYPB
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr15_+_84908573 0.09 ENST00000424966.1
ENST00000422563.2
GOLGA6L4
golgin A6 family-like 4
chr10_+_62538248 0.09 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr6_-_31689456 0.09 ENST00000495859.1
ENST00000375819.2
LY6G6C
lymphocyte antigen 6 complex, locus G6C
chr14_-_81408031 0.09 ENST00000216517.6
CEP128
centrosomal protein 128kDa
chr7_+_100136811 0.09 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr20_+_36012051 0.09 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr17_-_3195876 0.09 ENST00000323404.1
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr8_-_27468945 0.09 ENST00000405140.3
CLU
clusterin
chr2_+_181845298 0.09 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr12_+_57610562 0.09 ENST00000349394.5
NXPH4
neurexophilin 4
chr5_+_78532003 0.08 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr1_-_20306909 0.08 ENST00000375111.3
ENST00000400520.3
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr8_-_79717750 0.08 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr10_+_62538089 0.08 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chrM_+_9207 0.08 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr16_-_88752889 0.08 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr1_+_55271736 0.08 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr2_+_181845074 0.08 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr6_-_47009996 0.08 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr1_+_107683436 0.08 ENST00000370068.1
NTNG1
netrin G1
chr7_+_94139105 0.08 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr10_+_18689637 0.08 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_+_87285257 0.08 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr10_-_79397391 0.08 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_71774516 0.08 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr9_-_97402531 0.08 ENST00000415431.1
FBP1
fructose-1,6-bisphosphatase 1
chr1_-_1822495 0.08 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr19_+_58180303 0.08 ENST00000318203.5
ZSCAN4
zinc finger and SCAN domain containing 4
chr14_-_81408063 0.08 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr12_-_86650045 0.08 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_-_78365437 0.08 ENST00000380311.4
ENST00000540686.1
ENST00000255189.3
DMGDH
dimethylglycine dehydrogenase
chr12_-_55378452 0.08 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr16_+_23847339 0.08 ENST00000303531.7
PRKCB
protein kinase C, beta
chr1_-_53018654 0.08 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr15_-_58306295 0.07 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_+_240255166 0.07 ENST00000319653.9
FMN2
formin 2
chr5_+_125758865 0.07 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr22_+_25615489 0.07 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr9_+_116037922 0.07 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr1_-_12958101 0.07 ENST00000235347.4
PRAMEF10
PRAME family member 10
chr13_-_36050819 0.07 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_-_90229142 0.07 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr3_+_98072698 0.07 ENST00000354924.2
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr12_-_129570545 0.07 ENST00000389441.4
TMEM132D
transmembrane protein 132D
chr7_-_3214287 0.07 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr5_+_162864575 0.07 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr20_-_3154162 0.07 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr6_-_36725157 0.07 ENST00000393189.2
CPNE5
copine V
chr3_+_150264555 0.07 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr3_+_14444063 0.07 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr8_-_27468842 0.07 ENST00000523500.1
CLU
clusterin
chr8_-_27469196 0.07 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr3_+_9834179 0.06 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr12_-_88423164 0.06 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr7_-_126892303 0.06 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.3 GO:0050894 determination of affect(GO:0050894)
0.1 0.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 1.9 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.2 GO:0052314 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.0 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.3 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.0 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.2 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.6 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.1 2.0 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0045179 axon hillock(GO:0043203) apical cortex(GO:0045179)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.3 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)