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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXA4

Z-value: 0.49

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Transcription factors associated with HOXA4

Gene Symbol Gene ID Gene Info
HOXA4
ENSG00000197576.9 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA4hg19_v2_chr7_-_27170352_271704180.491.2e-02Click!

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_28586006 0.95 ENST00000253063.3
SESN2
sestrin 2
chr5_-_38557561 0.74 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr4_-_41884620 0.73 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr20_+_53092123 0.71 ENST00000262593.5
DOK5
docking protein 5
chr20_+_53092232 0.70 ENST00000395939.1
DOK5
docking protein 5
chr19_+_12949251 0.69 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr10_-_92681033 0.56 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr5_-_13944652 0.45 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr10_-_106240032 0.45 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr15_+_75080883 0.45 ENST00000567571.1
CSK
c-src tyrosine kinase
chr5_+_49962495 0.44 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr7_-_14026063 0.43 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr4_-_41884582 0.41 ENST00000499082.2
LINC00682
long intergenic non-protein coding RNA 682
chr7_-_27170352 0.39 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr8_-_95449155 0.37 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr5_+_67586465 0.34 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_+_90744533 0.31 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr13_-_46716969 0.29 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_88188254 0.29 ENST00000309495.5
ZNF654
zinc finger protein 654
chr8_-_28347737 0.28 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr3_-_52486841 0.28 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr5_-_1882858 0.28 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr6_+_50681541 0.26 ENST00000008391.3
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr17_-_39211463 0.26 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr4_+_88754069 0.26 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr2_+_171571827 0.25 ENST00000375281.3
SP5
Sp5 transcription factor
chr2_-_69098566 0.25 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr17_-_77924627 0.25 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr6_-_55739542 0.24 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr17_-_10452929 0.24 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr11_-_69633792 0.24 ENST00000334134.2
FGF3
fibroblast growth factor 3
chr11_+_5372738 0.23 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr3_-_188665428 0.23 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr4_+_88754113 0.23 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chrM_+_5824 0.23 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr8_+_77593474 0.22 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr1_-_100643765 0.22 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr1_+_167298281 0.22 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr7_+_107110488 0.22 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr10_-_69455873 0.21 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr8_+_77593448 0.21 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr2_-_180427304 0.21 ENST00000336917.5
ZNF385B
zinc finger protein 385B
chr2_-_145278475 0.21 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr10_-_105845674 0.21 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr1_+_155658849 0.20 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
DAP3
death associated protein 3
chr1_-_12677714 0.20 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr8_-_10512569 0.20 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr12_+_12938541 0.19 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr10_+_77056134 0.19 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr15_+_51669444 0.19 ENST00000396399.2
GLDN
gliomedin
chr5_+_49962772 0.19 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_40315640 0.19 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr18_+_13612613 0.18 ENST00000586765.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr16_+_7382745 0.18 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_100273736 0.17 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr18_+_28956740 0.17 ENST00000308128.4
ENST00000359747.4
DSG4
desmoglein 4
chr12_+_72058130 0.17 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr18_-_658244 0.17 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr3_+_137490748 0.17 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr17_-_10325261 0.17 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr14_+_37131058 0.16 ENST00000361487.6
PAX9
paired box 9
chr1_-_204329013 0.16 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_+_160160283 0.16 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr7_-_14028488 0.16 ENST00000405358.4
ETV1
ets variant 1
chr1_+_160160346 0.15 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr13_-_28545276 0.15 ENST00000381020.7
CDX2
caudal type homeobox 2
chr1_-_42384343 0.15 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr9_+_87284675 0.15 ENST00000376208.1
ENST00000304053.6
ENST00000277120.3
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr9_-_113761720 0.15 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr2_-_80531399 0.15 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr7_+_144052381 0.15 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr5_+_40909354 0.15 ENST00000313164.9
C7
complement component 7
chrX_-_55024967 0.14 ENST00000545676.1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_893200 0.14 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr12_-_57037284 0.13 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr9_+_87284622 0.13 ENST00000395882.1
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr14_+_39734482 0.13 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5
CTAGE family, member 5
chr3_+_107241783 0.13 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr3_+_188664988 0.12 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr20_-_45035223 0.12 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr10_-_62332357 0.12 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_10421853 0.12 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr10_-_95462265 0.12 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr2_-_163099885 0.12 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr12_+_53818855 0.12 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr11_-_5364809 0.12 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr7_-_14026123 0.11 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr8_+_22424551 0.11 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr5_+_60933634 0.11 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr11_+_112046190 0.11 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr7_+_95115210 0.10 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr6_-_31514516 0.10 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_+_108855558 0.10 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
RP11-59E19.1
chr6_-_117150198 0.10 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr9_+_44867571 0.10 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chrX_-_84634737 0.10 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr2_-_163100045 0.10 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr11_+_124481361 0.10 ENST00000284288.2
PANX3
pannexin 3
chr22_+_22930626 0.10 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr2_-_105030466 0.09 ENST00000449772.1
AC068535.3
AC068535.3
chr18_-_24128496 0.09 ENST00000417602.1
KCTD1
potassium channel tetramerization domain containing 1
chr8_-_139926236 0.09 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr14_-_36989336 0.09 ENST00000522719.2
NKX2-1
NK2 homeobox 1
chr18_-_21017817 0.09 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241
transmembrane protein 241
chr22_+_26138108 0.09 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B
myosin XVIIIB
chr6_-_31514333 0.09 ENST00000376151.4
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr6_+_31514622 0.08 ENST00000376146.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr12_-_91398796 0.08 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr6_+_50786414 0.08 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr16_+_6533380 0.08 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_-_48785216 0.08 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr7_+_7811992 0.08 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr17_-_56082455 0.08 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr7_+_129015484 0.08 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr5_+_152870106 0.08 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr15_+_89631647 0.08 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2
abhydrolase domain containing 2
chr15_+_89631381 0.08 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr4_+_189060573 0.07 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr4_+_66536248 0.07 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chrX_-_84634708 0.07 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr11_-_62313090 0.07 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr5_+_147582387 0.07 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr2_-_80531824 0.07 ENST00000295057.3
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr10_+_118305435 0.07 ENST00000369221.2
PNLIP
pancreatic lipase
chr5_+_133562095 0.07 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr3_+_122103014 0.07 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr17_-_10372875 0.06 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr1_-_108231101 0.06 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chrX_+_41548259 0.06 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr9_-_113341985 0.06 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr12_+_106976678 0.06 ENST00000392842.1
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr7_-_29234802 0.06 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr10_-_101825151 0.06 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr10_+_11047259 0.06 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr16_+_86229728 0.06 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr9_-_113342160 0.06 ENST00000401783.2
ENST00000374461.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr5_+_66300446 0.06 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_41548220 0.05 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr14_-_80697396 0.05 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr12_-_10959892 0.05 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr4_-_109541539 0.05 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr6_-_116447283 0.05 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr20_+_32150140 0.05 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chrX_+_37639302 0.05 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr3_-_57233966 0.04 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr7_-_14029283 0.04 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr2_+_53994927 0.04 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chr14_-_38064198 0.04 ENST00000250448.2
FOXA1
forkhead box A1
chr16_+_57728701 0.04 ENST00000569375.1
ENST00000360716.3
ENST00000569167.1
ENST00000394337.4
ENST00000563126.1
ENST00000336825.8
CCDC135
coiled-coil domain containing 135
chr13_-_84456527 0.04 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr6_-_26235206 0.04 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr10_-_75415825 0.04 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr13_-_53422640 0.04 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr5_+_152870734 0.03 ENST00000521843.2
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr12_-_11091862 0.03 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chrX_-_119445263 0.03 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chrX_-_119445306 0.03 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr14_-_36988882 0.03 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr7_+_117251671 0.03 ENST00000468795.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_+_53848549 0.03 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr12_-_86650045 0.03 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_+_80351910 0.02 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr11_+_27062860 0.02 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_140714430 0.02 ENST00000393008.3
MRPS33
mitochondrial ribosomal protein S33
chr12_-_86650077 0.01 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr17_+_54230819 0.01 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr5_+_152870287 0.01 ENST00000340592.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr11_-_13517565 0.01 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr12_+_27677085 0.01 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr6_+_152011628 0.01 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr5_+_69321074 0.01 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr6_-_55740352 0.00 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr4_-_185139062 0.00 ENST00000296741.2
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 1.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.3 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.4 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.3 GO:0014894 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.5 GO:0021670 lateral ventricle development(GO:0021670) outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation