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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXA6

Z-value: 0.55

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Transcription factors associated with HOXA6

Gene Symbol Gene ID Gene Info
HOXA6
ENSG00000106006.6 homeobox A6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v2_chr7_-_27187393_271873930.222.8e-01Click!

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27205136 2.67 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr7_-_27183263 2.36 ENST00000222726.3
HOXA5
homeobox A5
chr8_-_93107443 1.61 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_136172820 1.55 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr18_+_72922710 1.07 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr2_+_66662510 0.99 ENST00000272369.9
ENST00000407092.2
MEIS1
Meis homeobox 1
chr2_+_66662690 0.97 ENST00000488550.1
MEIS1
Meis homeobox 1
chr4_+_129730947 0.96 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr14_-_54423529 0.94 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr8_-_93107696 0.90 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_129730779 0.89 ENST00000226319.6
PHF17
jade family PHD finger 1
chr4_-_41884620 0.81 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr17_-_56082455 0.72 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr8_-_93107827 0.69 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_27723158 0.68 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr9_-_124989804 0.62 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr1_+_61869748 0.55 ENST00000357977.5
NFIA
nuclear factor I/A
chr2_-_164592497 0.54 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr18_-_22932080 0.54 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521
zinc finger protein 521
chr6_+_130339710 0.54 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr16_+_53242350 0.53 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_+_50681541 0.50 ENST00000008391.3
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr10_-_77161650 0.50 ENST00000372524.4
ZNF503
zinc finger protein 503
chr17_+_42634844 0.50 ENST00000315323.3
FZD2
frizzled family receptor 2
chr13_-_67802549 0.49 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr9_+_2015335 0.49 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_244214577 0.49 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr17_-_46671323 0.48 ENST00000239151.5
HOXB5
homeobox B5
chr15_+_96869165 0.48 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_-_88179302 0.47 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr11_+_22696314 0.44 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr7_-_41742697 0.43 ENST00000242208.4
INHBA
inhibin, beta A
chr1_+_65730385 0.43 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_+_6949964 0.43 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr11_+_123396528 0.41 ENST00000322282.7
ENST00000529750.1
GRAMD1B
GRAM domain containing 1B
chr7_-_27142290 0.40 ENST00000222718.5
HOXA2
homeobox A2
chr1_+_87797351 0.39 ENST00000370542.1
LMO4
LIM domain only 4
chr6_-_85474219 0.39 ENST00000369663.5
TBX18
T-box 18
chr14_-_98444438 0.39 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr16_+_53133070 0.38 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_176987088 0.38 ENST00000249499.6
HOXD9
homeobox D9
chr11_-_8290263 0.37 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr14_-_95236551 0.37 ENST00000238558.3
GSC
goosecoid homeobox
chr18_-_30353025 0.36 ENST00000359358.4
KLHL14
kelch-like family member 14
chr17_-_46688334 0.36 ENST00000239165.7
HOXB7
homeobox B7
chr5_+_161274940 0.36 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_104831554 0.36 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr9_+_2158485 0.35 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_177502659 0.34 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr20_-_50418947 0.33 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr7_-_14026123 0.33 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr16_+_53241854 0.33 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_112726393 0.32 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr20_-_50418972 0.32 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr9_+_2158443 0.31 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_37051798 0.31 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr7_+_107110488 0.31 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chrX_-_33146477 0.30 ENST00000378677.2
DMD
dystrophin
chr11_+_20620946 0.30 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr16_+_89334512 0.30 ENST00000602042.1
AC137932.1
AC137932.1
chr17_-_46682321 0.30 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr1_+_84630053 0.29 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_96876340 0.29 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_+_143929307 0.28 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr9_-_20622478 0.27 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_+_160188889 0.26 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_+_88188254 0.26 ENST00000309495.5
ZNF654
zinc finger protein 654
chr12_-_5352315 0.26 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr4_-_72649763 0.25 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr1_+_206557366 0.25 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_8285405 0.25 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr9_+_2159850 0.25 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrY_-_6742068 0.24 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr12_-_24103954 0.24 ENST00000441133.2
ENST00000545921.1
SOX5
SRY (sex determining region Y)-box 5
chr21_-_40033618 0.24 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr7_-_5463175 0.24 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr4_-_153274078 0.24 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_174151536 0.23 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr3_-_114477962 0.23 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr15_+_80364901 0.22 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr2_-_29297127 0.21 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr3_-_114477787 0.21 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_99871570 0.21 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr5_+_161275320 0.21 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_+_177015950 0.20 ENST00000306324.3
HOXD4
homeobox D4
chr9_+_77230499 0.20 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr12_-_122240792 0.20 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr6_-_32157947 0.20 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr3_-_114343039 0.20 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_10115007 0.20 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr15_-_54025300 0.20 ENST00000559418.1
WDR72
WD repeat domain 72
chr5_-_34043310 0.20 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr18_-_52989525 0.20 ENST00000457482.3
TCF4
transcription factor 4
chr12_-_102874330 0.19 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr20_+_11898507 0.19 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chrX_+_28605516 0.19 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_-_2334888 0.19 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr5_+_161274685 0.19 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_173316341 0.19 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr7_-_71868354 0.19 ENST00000412588.1
CALN1
calneuron 1
chrX_-_19688475 0.19 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_14133053 0.19 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr18_-_53089723 0.19 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr10_-_33623310 0.18 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr3_-_54962100 0.18 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr10_-_77161533 0.18 ENST00000535216.1
ZNF503
zinc finger protein 503
chr1_+_61330931 0.18 ENST00000371191.1
NFIA
nuclear factor I/A
chr1_+_167298281 0.18 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr3_+_152017360 0.17 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr16_-_67517716 0.17 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chrM_+_9207 0.17 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr20_+_32150140 0.17 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr21_-_31538971 0.17 ENST00000286808.3
CLDN17
claudin 17
chr2_-_183291741 0.16 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_-_104909435 0.16 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr4_+_41614720 0.16 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr17_-_10372875 0.16 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr12_-_102874102 0.15 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr9_-_14722715 0.15 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr10_-_106240032 0.14 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr4_-_116034979 0.14 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr17_-_46692287 0.14 ENST00000239144.4
HOXB8
homeobox B8
chr8_+_42873548 0.14 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr5_+_161494521 0.13 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr20_-_49547731 0.13 ENST00000396029.3
ADNP
activity-dependent neuroprotector homeobox
chr14_-_24551195 0.13 ENST00000560550.1
NRL
neural retina leucine zipper
chr21_-_39870339 0.13 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr14_+_72052983 0.13 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr15_+_36994210 0.13 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr4_+_41614909 0.13 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr8_-_122653630 0.13 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr9_-_124990680 0.13 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chr14_-_24551137 0.13 ENST00000396995.1
NRL
neural retina leucine zipper
chr1_-_102312517 0.13 ENST00000338858.5
OLFM3
olfactomedin 3
chr17_-_26220366 0.13 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr3_+_152017181 0.13 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr15_+_48498480 0.12 ENST00000380993.3
ENST00000396577.3
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr14_-_92413727 0.12 ENST00000267620.10
FBLN5
fibulin 5
chr2_-_161056762 0.12 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr5_-_88119580 0.12 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr15_+_71839566 0.11 ENST00000357769.4
THSD4
thrombospondin, type I, domain containing 4
chr18_-_53070913 0.11 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr5_-_124081008 0.11 ENST00000306315.5
ZNF608
zinc finger protein 608
chr18_-_53177984 0.11 ENST00000543082.1
TCF4
transcription factor 4
chr8_-_42234745 0.11 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr1_-_152131703 0.10 ENST00000316073.3
RPTN
repetin
chr2_-_50201327 0.10 ENST00000412315.1
NRXN1
neurexin 1
chr7_-_112727774 0.10 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr8_+_104892639 0.10 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr1_-_203055129 0.10 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr12_-_102591604 0.10 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr5_-_1882858 0.10 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr8_-_18744528 0.09 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr18_+_28956740 0.09 ENST00000308128.4
ENST00000359747.4
DSG4
desmoglein 4
chr14_-_92413353 0.09 ENST00000556154.1
FBLN5
fibulin 5
chr3_-_72149553 0.09 ENST00000468646.2
ENST00000464271.1
LINC00877
long intergenic non-protein coding RNA 877
chr5_+_59783540 0.09 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_168250194 0.09 ENST00000367821.3
TBX19
T-box 19
chr2_+_33359646 0.09 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.09 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_84630367 0.09 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_-_95131923 0.09 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr20_-_50419055 0.09 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr18_-_52989217 0.08 ENST00000570287.2
TCF4
transcription factor 4
chr12_-_16758304 0.08 ENST00000320122.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_-_13165457 0.08 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr1_-_186430222 0.08 ENST00000391997.2
PDC
phosducin
chr1_+_81771806 0.08 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr9_+_130026756 0.08 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr1_-_53608289 0.07 ENST00000371491.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr12_-_16758059 0.07 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_18541603 0.07 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_161494770 0.07 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_210444748 0.07 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr6_-_9933500 0.07 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr12_-_53994805 0.07 ENST00000328463.7
ATF7
activating transcription factor 7
chr2_+_182850551 0.07 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr8_-_133123406 0.07 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr14_+_61654271 0.07 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr14_-_98444461 0.07 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr3_+_69985792 0.06 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr5_-_76935513 0.06 ENST00000306422.3
OTP
orthopedia homeobox
chr20_+_59654146 0.06 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr15_+_58724184 0.06 ENST00000433326.2
LIPC
lipase, hepatic
chr3_+_35721182 0.06 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr22_-_36236623 0.05 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr18_+_32173276 0.05 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr11_+_131240373 0.05 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr12_-_16759711 0.05 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16761007 0.05 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr20_+_62795827 0.05 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr2_-_233641265 0.05 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
KCNJ13
potassium inwardly-rectifying channel, subfamily J, member 13
chrX_+_11311533 0.04 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX
amelogenin, X-linked
chr9_-_73483926 0.04 ENST00000396283.1
ENST00000361823.5
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr1_+_12538594 0.04 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr13_+_31774073 0.04 ENST00000343307.4
B3GALTL
beta 1,3-galactosyltransferase-like
chr2_+_210444142 0.04 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr6_+_42584847 0.04 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_217250231 0.03 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr5_-_27038683 0.03 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0060435 bronchiole development(GO:0060435)
0.3 0.9 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.1 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 1.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.5 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.2 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 3.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:2000741 asymmetric neuroblast division(GO:0055059) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:1903862 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)