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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXA6

Z-value: 0.55

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Transcription factors associated with HOXA6

Gene Symbol Gene ID Gene Info
ENSG00000106006.6 homeobox A6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v2_chr7_-_27187393_271873930.222.8e-01Click!

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27205136 2.67 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr7_-_27183263 2.36 ENST00000222726.3
homeobox A5
chr8_-_93107443 1.61 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_136172820 1.55 ENST00000308191.6
phosphodiesterase 7B
chr18_+_72922710 1.07 ENST00000322038.5
teashirt zinc finger homeobox 1
chr2_+_66662510 0.99 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr2_+_66662690 0.97 ENST00000488550.1
Meis homeobox 1
chr4_+_129730947 0.96 ENST00000452328.2
ENST00000504089.1
jade family PHD finger 1
chr14_-_54423529 0.94 ENST00000245451.4
ENST00000559087.1
bone morphogenetic protein 4
chr8_-_93107696 0.90 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_129730779 0.89 ENST00000226319.6
jade family PHD finger 1
chr4_-_41884620 0.81 ENST00000504870.1
long intergenic non-protein coding RNA 682
chr17_-_56082455 0.72 ENST00000578794.1
Uncharacterized protein
chr8_-_93107827 0.69 ENST00000520724.1
ENST00000518844.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_27723158 0.68 ENST00000395980.2
brain-derived neurotrophic factor
chr9_-_124989804 0.62 ENST00000373755.2
ENST00000373754.2
LIM homeobox 6
chr1_+_61869748 0.55 ENST00000357977.5
nuclear factor I/A
chr2_-_164592497 0.54 ENST00000333129.3
ENST00000409634.1
fidgetin
chr18_-_22932080 0.54 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
zinc finger protein 521
chr6_+_130339710 0.54 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr16_+_53242350 0.53 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr6_+_50681541 0.50 ENST00000008391.3
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr10_-_77161650 0.50 ENST00000372524.4
zinc finger protein 503
chr17_+_42634844 0.50 ENST00000315323.3
frizzled family receptor 2
chr13_-_67802549 0.49 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr9_+_2015335 0.49 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_244214577 0.49 ENST00000358704.4
zinc finger and BTB domain containing 18
chr17_-_46671323 0.48 ENST00000239151.5
homeobox B5
chr15_+_96869165 0.48 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr5_-_88179302 0.47 ENST00000504921.2
myocyte enhancer factor 2C
chr11_+_22696314 0.44 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr7_-_41742697 0.43 ENST00000242208.4
inhibin, beta A
chr1_+_65730385 0.43 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_+_6949964 0.43 ENST00000541978.1
ENST00000435982.2
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr11_+_123396528 0.41 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr7_-_27142290 0.40 ENST00000222718.5
homeobox A2
chr1_+_87797351 0.39 ENST00000370542.1
LIM domain only 4
chr6_-_85474219 0.39 ENST00000369663.5
T-box 18
chr14_-_98444438 0.39 ENST00000512901.2
chromosome 14 open reading frame 64
chr16_+_53133070 0.38 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr2_+_176987088 0.38 ENST00000249499.6
homeobox D9
chr11_-_8290263 0.37 ENST00000428101.2
LIM domain only 1 (rhombotin 1)
chr14_-_95236551 0.37 ENST00000238558.3
goosecoid homeobox
chr18_-_30353025 0.36 ENST00000359358.4
kelch-like family member 14
chr17_-_46688334 0.36 ENST00000239165.7
homeobox B7
chr5_+_161274940 0.36 ENST00000393943.4
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_104831554 0.36 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr9_+_2158485 0.35 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_177502659 0.34 ENST00000295549.4
long intergenic non-protein coding RNA 1116
chr20_-_50418947 0.33 ENST00000371539.3
spalt-like transcription factor 4
chr7_-_14026123 0.33 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chr16_+_53241854 0.33 ENST00000565803.1
chromodomain helicase DNA binding protein 9
chr7_-_112726393 0.32 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
G protein-coupled receptor 85
chr20_-_50418972 0.32 ENST00000395997.3
spalt-like transcription factor 4
chr9_+_2158443 0.31 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_37051798 0.31 ENST00000258829.5
NK2 homeobox 8
chr7_+_107110488 0.31 ENST00000304402.4
G protein-coupled receptor 22
chrX_-_33146477 0.30 ENST00000378677.2
dystrophin
chr11_+_20620946 0.30 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr16_+_89334512 0.30 ENST00000602042.1
AC137932.1
chr17_-_46682321 0.30 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr1_+_84630053 0.29 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_96876340 0.29 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr6_+_143929307 0.28 ENST00000427704.2
ENST00000305766.6
phosphatase and actin regulator 2
chr9_-_20622478 0.27 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_+_160188889 0.26 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr3_+_88188254 0.26 ENST00000309495.5
zinc finger protein 654
chr12_-_5352315 0.26 ENST00000536518.1
RP11-319E16.1
chr4_-_72649763 0.25 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr1_+_206557366 0.25 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_8285405 0.25 ENST00000335790.3
ENST00000534484.1
LIM domain only 1 (rhombotin 1)
chr9_+_2159850 0.25 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrY_-_6742068 0.24 ENST00000215479.5
amelogenin, Y-linked
chr12_-_24103954 0.24 ENST00000441133.2
ENST00000545921.1
SRY (sex determining region Y)-box 5
chr21_-_40033618 0.24 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chr7_-_5463175 0.24 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr4_-_153274078 0.24 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_174151536 0.23 ENST00000239243.6
ENST00000507785.1
msh homeobox 2
chr3_-_114477962 0.23 ENST00000471418.1
zinc finger and BTB domain containing 20
chr15_+_80364901 0.22 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr2_-_29297127 0.21 ENST00000331664.5
chromosome 2 open reading frame 71
chr3_-_114477787 0.21 ENST00000464560.1
zinc finger and BTB domain containing 20
chr2_-_99871570 0.21 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
lysozyme G-like 2
chr5_+_161275320 0.21 ENST00000437025.2
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_+_177015950 0.20 ENST00000306324.3
homeobox D4
chr9_+_77230499 0.20 ENST00000396204.2
RAR-related orphan receptor B
chr12_-_122240792 0.20 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr6_-_32157947 0.20 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr3_-_114343039 0.20 ENST00000481632.1
zinc finger and BTB domain containing 20
chr6_-_10115007 0.20 ENST00000485268.1
orofacial cleft 1 candidate 1
chr15_-_54025300 0.20 ENST00000559418.1
WD repeat domain 72
chr5_-_34043310 0.20 ENST00000231338.7
C1q and tumor necrosis factor related protein 3
chr18_-_52989525 0.20 ENST00000457482.3
transcription factor 4
chr12_-_102874330 0.19 ENST00000307046.8
insulin-like growth factor 1 (somatomedin C)
chr20_+_11898507 0.19 ENST00000378226.2
BTB (POZ) domain containing 3
chrX_+_28605516 0.19 ENST00000378993.1
interleukin 1 receptor accessory protein-like 1
chr2_-_2334888 0.19 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr5_+_161274685 0.19 ENST00000428797.2
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_173316341 0.19 ENST00000520867.1
ENST00000334035.5
cytoplasmic polyadenylation element binding protein 4
chr7_-_71868354 0.19 ENST00000412588.1
calneuron 1
chrX_-_19688475 0.19 ENST00000541422.1
SH3-domain kinase binding protein 1
chr12_-_14133053 0.19 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr18_-_53089723 0.19 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr10_-_33623310 0.18 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
neuropilin 1
chr3_-_54962100 0.18 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chr10_-_77161533 0.18 ENST00000535216.1
zinc finger protein 503
chr1_+_61330931 0.18 ENST00000371191.1
nuclear factor I/A
chr1_+_167298281 0.18 ENST00000367862.5
POU class 2 homeobox 1
chr3_+_152017360 0.17 ENST00000485910.1
ENST00000463374.1
muscleblind-like splicing regulator 1
chr16_-_67517716 0.17 ENST00000290953.2
agouti related protein homolog (mouse)
chrM_+_9207 0.17 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr20_+_32150140 0.17 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr21_-_31538971 0.17 ENST00000286808.3
claudin 17
chr2_-_183291741 0.16 ENST00000351439.5
ENST00000409365.1
phosphodiesterase 1A, calmodulin-dependent
chr7_-_104909435 0.16 ENST00000357311.3
SRSF protein kinase 2
chr4_+_41614720 0.16 ENST00000509277.1
LIM and calponin homology domains 1
chr17_-_10372875 0.16 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr12_-_102874102 0.15 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr9_-_14722715 0.15 ENST00000380911.3
cerberus 1, DAN family BMP antagonist
chr10_-_106240032 0.14 ENST00000447860.1
RP11-127O4.3
chr4_-_116034979 0.14 ENST00000264363.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr17_-_46692287 0.14 ENST00000239144.4
homeobox B8
chr8_+_42873548 0.14 ENST00000533338.1
ENST00000534420.1
hook microtubule-tethering protein 3
Uncharacterized protein
chr5_+_161494521 0.13 ENST00000356592.3
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr20_-_49547731 0.13 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr14_-_24551195 0.13 ENST00000560550.1
neural retina leucine zipper
chr21_-_39870339 0.13 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
v-ets avian erythroblastosis virus E26 oncogene homolog
chr14_+_72052983 0.13 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr15_+_36994210 0.13 ENST00000562489.1
chromosome 15 open reading frame 41
chr4_+_41614909 0.13 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr8_-_122653630 0.13 ENST00000303924.4
hyaluronan synthase 2
chr9_-_124990680 0.13 ENST00000541397.2
ENST00000560485.1
LIM homeobox 6
chr14_-_24551137 0.13 ENST00000396995.1
neural retina leucine zipper
chr1_-_102312517 0.13 ENST00000338858.5
olfactomedin 3
chr17_-_26220366 0.13 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr3_+_152017181 0.13 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr15_+_48498480 0.12 ENST00000380993.3
ENST00000396577.3
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr14_-_92413727 0.12 ENST00000267620.10
fibulin 5
chr2_-_161056762 0.12 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr5_-_88119580 0.12 ENST00000539796.1
myocyte enhancer factor 2C
chr15_+_71839566 0.11 ENST00000357769.4
thrombospondin, type I, domain containing 4
chr18_-_53070913 0.11 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr5_-_124081008 0.11 ENST00000306315.5
zinc finger protein 608
chr18_-_53177984 0.11 ENST00000543082.1
transcription factor 4
chr8_-_42234745 0.11 ENST00000220812.2
dickkopf WNT signaling pathway inhibitor 4
chr1_-_152131703 0.10 ENST00000316073.3
repetin
chr2_-_50201327 0.10 ENST00000412315.1
neurexin 1
chr7_-_112727774 0.10 ENST00000297146.3
ENST00000501255.2
G protein-coupled receptor 85
chr8_+_104892639 0.10 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr1_-_203055129 0.10 ENST00000241651.4
myogenin (myogenic factor 4)
chr12_-_102591604 0.10 ENST00000329406.4
pro-melanin-concentrating hormone
chr5_-_1882858 0.10 ENST00000511126.1
ENST00000231357.2
iroquois homeobox 4
chr8_-_18744528 0.09 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr18_+_28956740 0.09 ENST00000308128.4
ENST00000359747.4
desmoglein 4
chr14_-_92413353 0.09 ENST00000556154.1
fibulin 5
chr3_-_72149553 0.09 ENST00000468646.2
ENST00000464271.1
long intergenic non-protein coding RNA 877
chr5_+_59783540 0.09 ENST00000515734.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_168250194 0.09 ENST00000367821.3
T-box 19
chr2_+_33359646 0.09 ENST00000390003.4
ENST00000418533.2
latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.09 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
latent transforming growth factor beta binding protein 1
chr1_+_84630367 0.09 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr13_-_95131923 0.09 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr20_-_50419055 0.09 ENST00000217086.4
spalt-like transcription factor 4
chr18_-_52989217 0.08 ENST00000570287.2
transcription factor 4
chr12_-_16758304 0.08 ENST00000320122.6
LIM domain only 3 (rhombotin-like 2)
chr9_-_13165457 0.08 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr1_-_186430222 0.08 ENST00000391997.2
phosducin
chr1_+_81771806 0.08 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr9_+_130026756 0.08 ENST00000314904.5
ENST00000373387.4
GTPase activating Rap/RanGAP domain-like 3
chr1_-_53608289 0.07 ENST00000371491.4
solute carrier family 1 (glutamate transporter), member 7
chr12_-_16758059 0.07 ENST00000261169.6
LIM domain only 3 (rhombotin-like 2)
chr8_-_18541603 0.07 ENST00000428502.2
pleckstrin and Sec7 domain containing 3
chr5_+_161494770 0.07 ENST00000414552.2
ENST00000361925.4
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_210444748 0.07 ENST00000392194.1
microtubule-associated protein 2
chr6_-_9933500 0.07 ENST00000492169.1
orofacial cleft 1 candidate 1
chr12_-_53994805 0.07 ENST00000328463.7
activating transcription factor 7
chr2_+_182850551 0.07 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr8_-_133123406 0.07 ENST00000434736.2
HERV-H LTR-associating 1
chr14_+_61654271 0.07 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr14_-_98444461 0.07 ENST00000499006.2
chromosome 14 open reading frame 64
chr3_+_69985792 0.06 ENST00000531774.1
microphthalmia-associated transcription factor
chr5_-_76935513 0.06 ENST00000306422.3
orthopedia homeobox
chr20_+_59654146 0.06 ENST00000441660.1
RP5-827L5.1
chr15_+_58724184 0.06 ENST00000433326.2
lipase, hepatic
chr3_+_35721182 0.06 ENST00000413378.1
ENST00000417925.1
cAMP-regulated phosphoprotein, 21kDa
chr22_-_36236623 0.05 ENST00000405409.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr18_+_32173276 0.05 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr11_+_131240373 0.05 ENST00000374791.3
ENST00000436745.1
neurotrimin
chr12_-_16759711 0.05 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_16761007 0.05 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr20_+_62795827 0.05 ENST00000328439.1
ENST00000536311.1
myelin transcription factor 1
chr2_-_233641265 0.05 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chrX_+_11311533 0.04 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
amelogenin, X-linked
chr9_-_73483926 0.04 ENST00000396283.1
ENST00000361823.5
transient receptor potential cation channel, subfamily M, member 3
chr1_+_12538594 0.04 ENST00000543710.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr13_+_31774073 0.04 ENST00000343307.4
beta 1,3-galactosyltransferase-like
chr2_+_210444142 0.04 ENST00000360351.4
ENST00000361559.4
microtubule-associated protein 2
chr6_+_42584847 0.04 ENST00000372883.3
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_217250231 0.03 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr5_-_27038683 0.03 ENST00000511822.1
ENST00000231021.4
cadherin 9, type 2 (T1-cadherin)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0060435 bronchiole development(GO:0060435)
0.3 0.9 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 0.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 1.1 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 1.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.5 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.2 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.3 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 3.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:2000741 asymmetric neuroblast division(GO:0055059) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:1903862 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)