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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXA9

Z-value: 0.74

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Transcription factors associated with HOXA9

Gene Symbol Gene ID Gene Info
ENSG00000078399.11 homeobox A9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA9hg19_v2_chr7_-_27205136_27205164-0.554.1e-03Click!

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_101185290 4.64 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr15_+_67418047 3.18 ENST00000540846.2
SMAD family member 3
chr2_-_225811747 3.09 ENST00000409592.3
dedicator of cytokinesis 10
chr4_-_76944621 2.98 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr2_+_143635067 2.42 ENST00000264170.4
kynureninase
chr7_+_55177416 1.83 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr10_+_91092241 1.72 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr4_-_69536346 1.62 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr8_+_31497271 1.54 ENST00000520407.1
neuregulin 1
chr6_+_126240442 1.50 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr1_-_173176452 1.49 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr2_+_143635222 1.49 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr10_-_24770632 1.38 ENST00000596413.1
AL353583.1
chr21_+_37507210 1.28 ENST00000290354.5
carbonyl reductase 3
chr7_-_83824169 1.27 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_-_146833222 1.25 ENST00000534907.1
dihydropyrimidinase-like 3
chr2_-_197226875 1.24 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr12_-_57472522 1.19 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr2_+_161993465 1.11 ENST00000457476.1
TRAF family member-associated NFKB activator
chrX_+_9431324 1.02 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr8_-_20040638 0.91 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr11_-_108464465 0.89 ENST00000525344.1
exophilin 5
chr11_-_57092381 0.86 ENST00000358252.3
tankyrase 1 binding protein 1, 182kDa
chr1_-_89591749 0.84 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr10_+_24755416 0.84 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr2_+_161993412 0.82 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr10_-_14050522 0.80 ENST00000342409.2
FERM domain containing 4A
chr3_-_58613323 0.80 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr6_-_137539651 0.78 ENST00000543628.1
interferon gamma receptor 1
chr5_-_146833485 0.78 ENST00000398514.3
dihydropyrimidinase-like 3
chr2_+_232063260 0.75 ENST00000349938.4
armadillo repeat containing 9
chr4_+_39046615 0.75 ENST00000261425.3
ENST00000508137.2
kelch-like family member 5
chr11_-_104905840 0.74 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr22_+_30477000 0.73 ENST00000403975.1
HORMA domain containing 2
chr6_+_18155560 0.72 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
lysine (K)-specific demethylase 1B
chr4_-_70080449 0.70 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr5_-_94417314 0.69 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr3_-_190167571 0.69 ENST00000354905.2
transmembrane protein 207
chr8_-_10512569 0.68 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr15_+_63414760 0.67 ENST00000557972.1
lactamase, beta
chr11_-_126870655 0.66 ENST00000525144.2
kin of IRRE like 3 (Drosophila)
chr4_+_146539415 0.65 ENST00000281317.5
methylmalonic aciduria (cobalamin deficiency) cblA type
chr2_+_232063436 0.65 ENST00000440107.1
armadillo repeat containing 9
chr5_+_176731572 0.64 ENST00000503853.1
PRELI domain containing 1
chr9_-_95640218 0.62 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
zinc finger protein 484
chr4_-_48018580 0.61 ENST00000514170.1
cyclic nucleotide gated channel alpha 1
chr8_-_20040601 0.61 ENST00000265808.7
ENST00000522513.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr16_+_56691606 0.60 ENST00000334350.6
metallothionein 1F
chrX_+_95939638 0.60 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chrX_-_45629661 0.59 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr16_+_56691838 0.58 ENST00000394501.2
metallothionein 1F
chr16_+_56691911 0.58 ENST00000568475.1
metallothionein 1F
chrX_+_144908928 0.57 ENST00000408967.2
transmembrane protein 257
chr11_+_6866883 0.57 ENST00000299454.4
ENST00000379831.2
olfactory receptor, family 10, subfamily A, member 5
chr1_+_50575292 0.57 ENST00000371821.1
ENST00000371819.1
ELAV like neuron-specific RNA binding protein 4
chr1_+_50574585 0.55 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr6_+_26365443 0.55 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr14_+_22977587 0.54 ENST00000390504.1
T cell receptor alpha joining 33
chr2_-_209028300 0.54 ENST00000304502.4
crystallin, gamma A
chr10_-_90712520 0.53 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr2_-_69098566 0.50 ENST00000295379.1
bone morphogenetic protein 10
chr22_-_30642782 0.50 ENST00000249075.3
leukemia inhibitory factor
chr17_-_37934466 0.49 ENST00000583368.1
IKAROS family zinc finger 3 (Aiolos)
chr12_+_21207503 0.48 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrX_-_63615297 0.47 ENST00000374852.3
ENST00000453546.1
myotubularin related protein 8
chr20_+_43211149 0.47 ENST00000372886.1
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr16_+_70613770 0.47 ENST00000429149.2
ENST00000563721.2
interleukin 34
chr17_-_39165366 0.47 ENST00000391588.1
keratin associated protein 3-1
chr3_+_119298523 0.46 ENST00000357003.3
ADP-ribosylarginine hydrolase
chr2_+_108994466 0.46 ENST00000272452.2
sulfotransferase family, cytosolic, 1C, member 4
chr3_-_112693865 0.46 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200 receptor 1
chr21_-_19775973 0.46 ENST00000284885.3
transmembrane protease, serine 15
chr2_+_171571827 0.46 ENST00000375281.3
Sp5 transcription factor
chr21_-_30257669 0.45 ENST00000303775.5
ENST00000351429.3
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr5_+_68485433 0.44 ENST00000502689.1
centromere protein H
chr7_-_27169801 0.44 ENST00000511914.1
homeobox A4
chrX_-_110513703 0.44 ENST00000324068.1
calpain 6
chr11_-_5345582 0.43 ENST00000328813.2
olfactory receptor, family 51, subfamily B, member 2
chr6_+_160327974 0.42 ENST00000252660.4
MAS1 oncogene
chr2_-_190044480 0.41 ENST00000374866.3
collagen, type V, alpha 2
chr16_+_67063855 0.40 ENST00000563939.2
core-binding factor, beta subunit
chr11_+_5474638 0.39 ENST00000341449.2
olfactory receptor, family 51, subfamily I, member 2
chr17_+_73663402 0.39 ENST00000355423.3
SAP30 binding protein
chr12_-_121477039 0.39 ENST00000257570.5
2'-5'-oligoadenylate synthetase-like
chr9_-_134955246 0.38 ENST00000357028.2
ENST00000474263.1
ENST00000292035.5
mediator complex subunit 27
chr2_-_130031335 0.37 ENST00000375987.3
AC079586.1
chr6_-_138539627 0.37 ENST00000527246.2
prostate and breast cancer overexpressed 1
chr18_+_9102592 0.37 ENST00000318388.6
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr1_-_7913089 0.37 ENST00000361696.5
urotensin 2
chr11_-_22647350 0.37 ENST00000327470.3
Fanconi anemia, complementation group F
chr2_+_108994633 0.37 ENST00000409309.3
sulfotransferase family, cytosolic, 1C, member 4
chr9_-_95244781 0.36 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr10_+_15001430 0.36 ENST00000407572.1
meiosis/spermiogenesis associated 1
chr2_+_27255806 0.36 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr2_-_88427568 0.35 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr12_-_13248598 0.34 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chr1_-_197169672 0.34 ENST00000367405.4
zinc finger and BTB domain containing 41
chr3_-_195310802 0.34 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr6_+_108977520 0.34 ENST00000540898.1
forkhead box O3
chr10_+_102222798 0.34 ENST00000343737.5
wingless-type MMTV integration site family, member 8B
chr16_+_3074002 0.33 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
THO complex 6 homolog (Drosophila)
chr3_+_185300391 0.33 ENST00000545472.1
SUMO1/sentrin/SMT3 specific peptidase 2
chr19_-_42133420 0.33 ENST00000221954.2
ENST00000600925.1
carcinoembryonic antigen-related cell adhesion molecule 4
chr7_+_128312346 0.32 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
family with sequence similarity 71, member F2
chr7_+_20370746 0.31 ENST00000222573.4
integrin, beta 8
chr5_+_34915444 0.31 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr17_-_7232585 0.31 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
neuralized E3 ubiquitin protein ligase 4
chr6_+_111195973 0.30 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr12_+_122181529 0.30 ENST00000541467.1
transmembrane protein 120B
chr15_+_59730348 0.30 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr7_+_120628731 0.30 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chrX_+_95939711 0.29 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr1_-_85100703 0.28 ENST00000370624.1
chromosome 1 open reading frame 180
chr18_+_45778672 0.28 ENST00000600091.1
HCG1818186; Uncharacterized protein
chr7_+_119913688 0.28 ENST00000331113.4
potassium voltage-gated channel, Shal-related subfamily, member 2
chr2_-_209051727 0.28 ENST00000453017.1
ENST00000423952.2
chromosome 2 open reading frame 80
chr4_-_74964904 0.28 ENST00000508487.2
chemokine (C-X-C motif) ligand 2
chr2_+_27799389 0.28 ENST00000408964.2
chromosome 2 open reading frame 16
chr3_-_108836977 0.27 ENST00000232603.5
MORC family CW-type zinc finger 1
chr1_+_44584522 0.27 ENST00000372299.3
Kruppel-like factor 17
chr4_-_159644507 0.27 ENST00000307720.3
peptidylprolyl isomerase D
chr2_+_89986318 0.27 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr18_-_72264805 0.27 ENST00000577806.1
long intergenic non-protein coding RNA 909
chr3_+_108321623 0.27 ENST00000497905.1
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr4_+_113970772 0.26 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr17_+_60447579 0.26 ENST00000450662.2
EF-hand calcium binding domain 3
chr15_+_40643227 0.26 ENST00000448599.2
proline/histidine/glycine-rich 1
chr6_-_9939552 0.26 ENST00000460363.2
orofacial cleft 1 candidate 1
chr12_+_70219052 0.26 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr19_-_10420459 0.25 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr12_-_13248705 0.25 ENST00000396310.2
germ cell associated 1
chrX_-_13338518 0.25 ENST00000380622.2
ataxin 3-like
chr1_+_117963209 0.25 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr1_-_36948879 0.25 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
colony stimulating factor 3 receptor (granulocyte)
chr12_-_13248732 0.25 ENST00000396302.3
germ cell associated 1
chr1_-_153085984 0.25 ENST00000468739.1
small proline-rich protein 2F
chr6_-_25832254 0.25 ENST00000476801.1
ENST00000244527.4
ENST00000427328.1
solute carrier family 17 (organic anion transporter), member 1
chr5_-_101834617 0.25 ENST00000513675.1
ENST00000379807.3
solute carrier organic anion transporter family, member 6A1
chr6_+_99282570 0.24 ENST00000328345.5
POU class 3 homeobox 2
chr2_+_208423840 0.24 ENST00000539789.1
cAMP responsive element binding protein 1
chr5_+_38845960 0.24 ENST00000502536.1
oncostatin M receptor
chr8_+_24151620 0.24 ENST00000437154.2
ADAM metallopeptidase domain 28
chr19_+_50529212 0.24 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
zinc finger protein 473
chr17_+_4853442 0.24 ENST00000522301.1
enolase 3 (beta, muscle)
chr15_-_68497657 0.24 ENST00000448060.2
ENST00000467889.1
calmodulin-like 4
chr15_+_65134088 0.24 ENST00000323544.4
ENST00000437723.1
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr2_+_149894968 0.24 ENST00000409642.3
LY6/PLAUR domain containing 6B
chr8_+_16884740 0.23 ENST00000318063.5
mitochondrial calcium uptake family, member 3
chr18_-_72265035 0.23 ENST00000585279.1
ENST00000580048.1
long intergenic non-protein coding RNA 909
chr4_-_109090106 0.23 ENST00000379951.2
lymphoid enhancer-binding factor 1
chr3_+_35721106 0.23 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr5_-_101834712 0.23 ENST00000506729.1
ENST00000389019.3
ENST00000379810.1
solute carrier organic anion transporter family, member 6A1
chr8_+_24151553 0.23 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr11_-_3400330 0.23 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
zinc finger protein 195
chr1_+_24645807 0.23 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr14_+_97925151 0.23 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
chr2_+_11864458 0.23 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
lipin 1
chr2_-_224467093 0.23 ENST00000305409.2
secretogranin II
chr12_-_13248562 0.22 ENST00000457134.2
ENST00000537302.1
germ cell associated 1
chr5_-_43515231 0.22 ENST00000306862.2
chromosome 5 open reading frame 34
chr1_-_11024258 0.22 ENST00000418570.2
chromosome 1 open reading frame 127
chr11_-_3400442 0.22 ENST00000429541.2
ENST00000532539.1
zinc finger protein 195
chr12_+_122880045 0.22 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
chr19_+_50528971 0.21 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
zinc finger protein 473
chr7_+_117251671 0.21 ENST00000468795.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr14_-_78174344 0.21 ENST00000216489.3
alkB, alkylation repair homolog 1 (E. coli)
chr6_-_133035185 0.21 ENST00000367928.4
vanin 1
chr12_-_54778471 0.21 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
zinc finger protein 385A
chr7_+_23749767 0.21 ENST00000355870.3
serine/threonine kinase 31
chr3_+_178276488 0.21 ENST00000432997.1
ENST00000455865.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_+_233390863 0.21 ENST00000449596.1
ENST00000543200.1
cholinergic receptor, nicotinic, delta (muscle)
chr15_+_33022885 0.21 ENST00000322805.4
gremlin 1, DAN family BMP antagonist
chrX_-_13835147 0.21 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_63428752 0.21 ENST00000295894.5
synaptoporin
chr5_+_149877334 0.21 ENST00000523767.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_3982548 0.21 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
poly (ADP-ribose) polymerase family, member 11
chr3_+_157154578 0.20 ENST00000295927.3
pentraxin 3, long
chr5_-_148758839 0.20 ENST00000261796.3
interleukin 17B
chr3_+_138340067 0.20 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr12_-_9913489 0.20 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr4_-_77328458 0.20 ENST00000388914.3
ENST00000434846.2
coiled-coil domain containing 158
chr10_+_64893039 0.20 ENST00000277746.6
ENST00000435510.2
nuclear receptor binding factor 2
chr2_+_32502952 0.20 ENST00000238831.4
Yip1 domain family, member 4
chr15_+_66797455 0.19 ENST00000446801.2
zwilch kinetochore protein
chr7_+_54609995 0.19 ENST00000302287.3
ENST00000407838.3
V-set and transmembrane domain containing 2A
chr13_-_46425865 0.19 ENST00000400405.2
siah E3 ubiquitin protein ligase family member 3
chr4_+_70796784 0.19 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr16_-_18911366 0.19 ENST00000565224.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_-_207095324 0.19 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr1_+_101702417 0.19 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr9_+_71819927 0.19 ENST00000535702.1
tight junction protein 2
chr7_+_23749945 0.19 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
serine/threonine kinase 31
chr5_-_54281491 0.18 ENST00000381405.4
endothelial cell-specific molecule 1
chr11_-_108464321 0.18 ENST00000265843.4
exophilin 5
chr1_+_104615595 0.18 ENST00000418362.1
RP11-364B6.1
chr9_-_27529726 0.18 ENST00000262244.5
MOB kinase activator 3B
chr3_-_48130707 0.18 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chr8_+_55528627 0.18 ENST00000220676.1
retinitis pigmentosa 1 (autosomal dominant)
chr1_+_192127578 0.18 ENST00000367460.3
regulator of G-protein signaling 18
chr17_+_73663470 0.17 ENST00000583536.1
SAP30 binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.7 4.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.6 3.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.5 1.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5 1.8 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 1.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 3.0 GO:1901509 positive regulation of cAMP-mediated signaling(GO:0043950) regulation of endothelial tube morphogenesis(GO:1901509)
0.3 1.3 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3 1.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.3 GO:0048880 sensory system development(GO:0048880)
0.2 3.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.7 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.1 2.0 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.7 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.7 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.5 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.2 GO:0035552 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 2.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.5 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0033152 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.3 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.7 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.6 1.8 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 3.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.5 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:1990423 RZZ complex(GO:1990423)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.8 GO:0043197 dendritic spine(GO:0043197)
0.0 3.9 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6 3.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.6 3.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 4.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 1.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 1.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 2.8 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 6.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors