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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXB3

Z-value: 0.52

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
ENSG00000120093.7 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667628_46667642-0.125.7e-01Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102651343 1.20 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr6_+_127898312 0.91 ENST00000329722.7
chromosome 6 open reading frame 58
chr4_+_86525299 0.87 ENST00000512201.1
Rho GTPase activating protein 24
chr5_-_61031495 0.68 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr1_+_79115503 0.68 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr6_-_82462425 0.62 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr7_-_92777606 0.54 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr21_-_37914898 0.48 ENST00000399136.1
claudin 14
chr11_+_5710919 0.46 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr1_+_62439037 0.45 ENST00000545929.1
InaD-like (Drosophila)
chr2_-_202563414 0.44 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_160160346 0.43 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_-_51422017 0.42 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_160160283 0.42 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr15_-_55562479 0.41 ENST00000564609.1
RAB27A, member RAS oncogene family
chr2_+_143635067 0.39 ENST00000264170.4
kynureninase
chr15_-_55563072 0.39 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr18_+_61554932 0.39 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_-_117748138 0.38 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr11_-_104905840 0.37 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr18_+_55888767 0.37 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr15_-_55562582 0.36 ENST00000396307.2
RAB27A, member RAS oncogene family
chr11_+_33061543 0.35 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr2_-_220264703 0.35 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr5_-_159546396 0.34 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr2_-_120282070 0.33 ENST00000019103.5
secretin receptor
chr1_-_67266939 0.32 ENST00000304526.2
insulin-like 5
chr19_-_3557570 0.31 ENST00000355415.2
major facilitator superfamily domain containing 12
chr15_-_101835110 0.31 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr2_-_10587897 0.30 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr10_-_31288398 0.30 ENST00000538351.2
zinc finger protein 438
chr7_-_99764853 0.30 ENST00000411994.1
ENST00000426974.2
galactose-3-O-sulfotransferase 4
chrX_+_144908928 0.30 ENST00000408967.2
transmembrane protein 257
chr5_+_110427983 0.30 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr16_+_50730910 0.29 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr22_-_32651326 0.28 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr10_-_22292613 0.28 ENST00000376980.3
DnaJ (Hsp40) homolog, subfamily C, member 1
chr12_+_20848377 0.28 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
solute carrier organic anion transporter family, member 1C1
chr22_+_21996549 0.27 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr10_-_4285923 0.27 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr4_-_120243545 0.27 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr1_+_144989309 0.26 ENST00000596396.1
Uncharacterized protein
chr6_-_62996066 0.26 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr2_+_187371440 0.25 ENST00000445547.1
zinc finger CCCH-type containing 15
chr16_+_31885079 0.25 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr2_+_11682790 0.24 ENST00000389825.3
ENST00000381483.2
growth regulation by estrogen in breast cancer 1
chr2_+_143635222 0.24 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr12_+_112563335 0.23 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr12_+_112563303 0.23 ENST00000412615.2
TRAF-type zinc finger domain containing 1
chr7_+_120628731 0.22 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr11_-_107729887 0.22 ENST00000525815.1
solute carrier family 35, member F2
chr12_-_10959892 0.22 ENST00000240615.2
taste receptor, type 2, member 8
chr9_-_5339873 0.22 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr6_+_53883708 0.21 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr2_+_183982238 0.21 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
nucleoporin 35kDa
chr11_-_104827425 0.21 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr2_+_65215604 0.21 ENST00000531327.1
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_160370344 0.21 ENST00000368061.2
VANGL planar cell polarity protein 2
chr16_-_28621298 0.21 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_28410128 0.21 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr20_+_9494987 0.20 ENST00000427562.2
ENST00000246070.2
lysosomal-associated membrane protein family, member 5
chr8_-_13134045 0.20 ENST00000512044.2
deleted in liver cancer 1
chr15_+_64680003 0.20 ENST00000261884.3
thyroid hormone receptor interactor 4
chr13_-_47471155 0.20 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr19_+_10362577 0.20 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
mitochondrial ribosomal protein L4
chr13_+_102142296 0.20 ENST00000376162.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_-_26593779 0.19 ENST00000529533.1
mucin 15, cell surface associated
chr3_+_147795932 0.19 ENST00000490465.1
RP11-639B1.1
chr10_+_18549645 0.19 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr16_-_28621312 0.19 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_155006300 0.19 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DC-STAMP domain containing 1
chr7_-_24797546 0.19 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
deafness, autosomal dominant 5
chr19_+_10362882 0.19 ENST00000393733.2
ENST00000588502.1
mitochondrial ribosomal protein L4
chr2_+_196313239 0.19 ENST00000413290.1
AC064834.1
chrX_-_48824793 0.18 ENST00000376477.1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_231004220 0.18 ENST00000366663.5
chromosome 1 open reading frame 198
chr10_+_6779326 0.18 ENST00000417112.1
RP11-554I8.2
chr12_-_122985067 0.18 ENST00000540586.1
ENST00000543897.1
zinc finger, CCHC domain containing 8
chrX_-_77225135 0.18 ENST00000458128.1
phosphoglycerate mutase family member 4
chr5_-_96478466 0.17 ENST00000274382.4
Lix1 homolog (chicken)
chr19_+_48949030 0.17 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr9_+_130911770 0.17 ENST00000372998.1
lipocalin 2
chr2_+_208423840 0.17 ENST00000539789.1
cAMP responsive element binding protein 1
chr15_-_101835414 0.17 ENST00000254193.6
small nuclear ribonucleoprotein polypeptide A'
chr14_+_74034310 0.16 ENST00000538782.1
acyl-CoA thioesterase 2
chr3_-_151034734 0.16 ENST00000260843.4
G protein-coupled receptor 87
chr16_-_31085514 0.16 ENST00000300849.4
zinc finger protein 668
chr11_-_26593649 0.16 ENST00000455601.2
mucin 15, cell surface associated
chr7_+_5919458 0.16 ENST00000416608.1
oncomodulin
chr12_+_7014126 0.16 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr11_-_26593677 0.16 ENST00000527569.1
mucin 15, cell surface associated
chr10_+_53806501 0.16 ENST00000373975.2
protein kinase, cGMP-dependent, type I
chr4_+_110736659 0.15 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr2_+_29336855 0.15 ENST00000404424.1
CAP-GLY domain containing linker protein family, member 4
chrX_-_39923656 0.15 ENST00000413905.1
BCL6 corepressor
chr17_-_73901494 0.15 ENST00000309352.3
mitochondrial ribosomal protein L38
chr7_+_129015484 0.15 ENST00000490911.1
adenosylhomocysteinase-like 2
chr1_-_51796226 0.15 ENST00000451380.1
ENST00000371747.3
ENST00000439482.1
tetratricopeptide repeat domain 39A
chr2_+_168675182 0.14 ENST00000305861.1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr16_-_11036300 0.14 ENST00000331808.4
Dexi homolog (mouse)
chr19_-_6737576 0.14 ENST00000601716.1
ENST00000264080.7
G protein-coupled receptor 108
chr14_+_22320634 0.14 ENST00000390435.1
T cell receptor alpha variable 8-3
chr2_-_89160770 0.14 ENST00000390240.2
immunoglobulin kappa joining 3
chr11_-_104817919 0.14 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr20_-_5485166 0.14 ENST00000589201.1
ENST00000379053.4
long intergenic non-protein coding RNA 654
chr7_+_99202003 0.14 ENST00000609449.1
GS1-259H13.2
chr6_+_26045603 0.13 ENST00000540144.1
histone cluster 1, H3c
chr17_-_40337470 0.13 ENST00000293330.1
hypocretin (orexin) neuropeptide precursor
chr19_-_46088068 0.12 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr10_-_27529486 0.12 ENST00000375888.1
acyl-CoA binding domain containing 5
chr17_-_8770956 0.12 ENST00000311434.9
phosphoinositide-3-kinase, regulatory subunit 6
chr9_+_130911723 0.12 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr4_+_113568207 0.12 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr4_-_164534657 0.11 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_121944491 0.11 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr16_+_31366536 0.11 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_+_67219867 0.11 ENST00000438189.2
calcium binding protein 4
chr3_+_114012819 0.11 ENST00000383671.3
T cell immunoreceptor with Ig and ITIM domains
chr6_-_82957433 0.11 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_88125471 0.11 ENST00000398146.3
RANBP2-like and GRIP domain containing 2
chr14_+_57671888 0.11 ENST00000391612.1
AL391152.1
chr7_-_122339162 0.10 ENST00000340112.2
ring finger protein 133
chr4_-_111563076 0.10 ENST00000354925.2
ENST00000511990.1
paired-like homeodomain 2
chr21_+_31768348 0.10 ENST00000355459.2
keratin associated protein 13-1
chr12_-_5352315 0.10 ENST00000536518.1
RP11-319E16.1
chr3_-_151047327 0.10 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr17_-_62208169 0.10 ENST00000606895.1
endoplasmic reticulum to nucleus signaling 1
chr12_+_22778116 0.10 ENST00000538218.1
ethanolamine kinase 1
chr8_-_623547 0.10 ENST00000522893.1
glutamate-rich 1
chrX_-_21676442 0.10 ENST00000379499.2
kelch-like family member 34
chr2_+_234545148 0.10 ENST00000373445.1
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_207226313 0.10 ENST00000367084.1
YOD1 deubiquitinase
chr1_-_13390765 0.09 ENST00000357367.2
PRAME family member 8
chr6_+_149721495 0.09 ENST00000326669.4
small ubiquitin-like modifier 4
chr12_-_6740802 0.09 ENST00000431922.1
lysophosphatidic acid receptor 5
chrX_+_41548259 0.09 ENST00000378138.5
G protein-coupled receptor 34
chr2_+_89184868 0.09 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr12_-_117175819 0.09 ENST00000261318.3
ENST00000536380.1
chromosome 12 open reading frame 49
chr5_+_115177178 0.09 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr19_-_6424783 0.09 ENST00000398148.3
KH-type splicing regulatory protein
chr6_+_45296391 0.09 ENST00000371436.6
ENST00000576263.1
runt-related transcription factor 2
chr15_+_78830023 0.08 ENST00000599596.1
HCG2005369; Uncharacterized protein
chr11_-_96076334 0.08 ENST00000524717.1
mastermind-like 2 (Drosophila)
chr1_-_146040968 0.08 ENST00000401010.3
neuroblastoma breakpoint family, member 11
chr12_+_55248289 0.08 ENST00000308796.6
mucin-like 1
chr5_+_129083772 0.08 ENST00000564719.1
KIAA1024-like
chrX_+_102024075 0.08 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr12_-_123187890 0.08 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chrX_+_41548220 0.08 ENST00000378142.4
G protein-coupled receptor 34
chr2_+_113816215 0.08 ENST00000346807.3
interleukin 36 receptor antagonist
chr4_-_8873531 0.08 ENST00000400677.3
H6 family homeobox 1
chr8_+_50824233 0.08 ENST00000522124.1
syntrophin, gamma 1
chr12_-_123201337 0.08 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr2_-_113810444 0.08 ENST00000259213.4
ENST00000327407.2
interleukin 36, beta
chr5_+_55149150 0.08 ENST00000297015.3
interleukin 31 receptor A
chr16_+_31724552 0.07 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
zinc finger protein 720
chr11_-_119991589 0.07 ENST00000526881.1
tripartite motif containing 29
chr1_+_197237352 0.07 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr5_-_32444828 0.07 ENST00000265069.8
zinc finger RNA binding protein
chr5_+_140019004 0.07 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chrX_+_83116142 0.07 ENST00000329312.4
cylicin, basic protein of sperm head cytoskeleton 1
chr4_-_138453559 0.07 ENST00000511115.1
protocadherin 18
chr2_+_228736321 0.07 ENST00000309931.2
dynein assembly factor with WDR repeat domains 1
chr9_+_135937365 0.07 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr18_+_268148 0.07 ENST00000581677.1
RP11-705O1.8
chr1_+_202317815 0.07 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr1_+_156030937 0.07 ENST00000361084.5
RAB25, member RAS oncogene family
chr14_-_24711865 0.07 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_78753496 0.07 ENST00000548512.1
RP11-38F22.1
chr9_+_124329336 0.07 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr15_+_84841242 0.07 ENST00000558195.1
ubiquitin-conjugating enzyme E2Q family member 2-like
chr9_-_100707116 0.07 ENST00000259456.3
hemogen
chr14_-_24711806 0.07 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr11_+_63273811 0.07 ENST00000340246.5
lectin, galactoside-binding, soluble, 12
chr6_+_34204642 0.07 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr16_+_6069072 0.06 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_169887827 0.06 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr16_-_66864806 0.06 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr2_+_197577841 0.06 ENST00000409270.1
coiled-coil domain containing 150
chrX_+_106045891 0.06 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr4_-_100212132 0.06 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_+_26204825 0.06 ENST00000360441.4
histone cluster 1, H4e
chr1_+_207226574 0.06 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_-_119182523 0.06 ENST00000319172.5
transmembrane protein 39A
chr6_-_119256279 0.06 ENST00000316068.3
minichromosome maintenance complex component 9
chr14_+_32798462 0.06 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr1_+_144173162 0.06 ENST00000356801.6
neuroblastoma breakpoint family, member 8
chr3_-_126327398 0.06 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr2_-_3606206 0.06 ENST00000315212.3
ribonuclease H1
chr1_+_202317855 0.06 ENST00000356764.2
protein phosphatase 1, regulatory subunit 12B
chr4_-_52883786 0.06 ENST00000343457.3
leucine rich repeat containing 66
chr5_-_108063949 0.05 ENST00000606054.1
long intergenic non-protein coding RNA 1023
chr6_+_36562132 0.05 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chrX_+_135730373 0.05 ENST00000370628.2
CD40 ligand
chr6_-_133035185 0.05 ENST00000367928.4
vanin 1
chr11_-_95522907 0.05 ENST00000358780.5
ENST00000542135.1
family with sequence similarity 76, member B
chr10_-_135379132 0.05 ENST00000343131.5
synaptonemal complex central element protein 1
chr5_+_140019079 0.05 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr4_+_40198527 0.05 ENST00000381799.5
ras homolog family member H
chr2_+_166095898 0.05 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0035419 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.8 GO:0014877 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline