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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXB3

Z-value: 0.52

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.7 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667628_46667642-0.125.7e-01Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102651343 1.20 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr6_+_127898312 0.91 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr4_+_86525299 0.87 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr5_-_61031495 0.68 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
CTD-2170G1.2
chr1_+_79115503 0.68 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr6_-_82462425 0.62 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr7_-_92777606 0.54 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr21_-_37914898 0.48 ENST00000399136.1
CLDN14
claudin 14
chr11_+_5710919 0.46 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr1_+_62439037 0.45 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_-_202563414 0.44 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_160160346 0.43 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_-_51422017 0.42 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_160160283 0.42 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr15_-_55562479 0.41 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr2_+_143635067 0.39 ENST00000264170.4
KYNU
kynureninase
chr15_-_55563072 0.39 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr18_+_61554932 0.39 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_-_117748138 0.38 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_104905840 0.37 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr18_+_55888767 0.37 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr15_-_55562582 0.36 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_+_33061543 0.35 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr2_-_220264703 0.35 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr5_-_159546396 0.34 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr2_-_120282070 0.33 ENST00000019103.5
SCTR
secretin receptor
chr1_-_67266939 0.32 ENST00000304526.2
INSL5
insulin-like 5
chr19_-_3557570 0.31 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr15_-_101835110 0.31 ENST00000560496.1
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr2_-_10587897 0.30 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr10_-_31288398 0.30 ENST00000538351.2
ZNF438
zinc finger protein 438
chr7_-_99764853 0.30 ENST00000411994.1
ENST00000426974.2
GAL3ST4
galactose-3-O-sulfotransferase 4
chrX_+_144908928 0.30 ENST00000408967.2
TMEM257
transmembrane protein 257
chr5_+_110427983 0.30 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr16_+_50730910 0.29 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr22_-_32651326 0.28 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr10_-_22292613 0.28 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr12_+_20848377 0.28 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr22_+_21996549 0.27 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr10_-_4285923 0.27 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr4_-_120243545 0.27 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr1_+_144989309 0.26 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr6_-_62996066 0.26 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr2_+_187371440 0.25 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr16_+_31885079 0.25 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr2_+_11682790 0.24 ENST00000389825.3
ENST00000381483.2
GREB1
growth regulation by estrogen in breast cancer 1
chr2_+_143635222 0.24 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr12_+_112563335 0.23 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_+_112563303 0.23 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr7_+_120628731 0.22 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_107729887 0.22 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr12_-_10959892 0.22 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr9_-_5339873 0.22 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr6_+_53883708 0.21 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr2_+_183982238 0.21 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
NUP35
nucleoporin 35kDa
chr11_-_104827425 0.21 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_65215604 0.21 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_160370344 0.21 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr16_-_28621298 0.21 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_28410128 0.21 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr20_+_9494987 0.20 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr8_-_13134045 0.20 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr15_+_64680003 0.20 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr13_-_47471155 0.20 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr19_+_10362577 0.20 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
MRPL4
mitochondrial ribosomal protein L4
chr13_+_102142296 0.20 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_-_26593779 0.19 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr3_+_147795932 0.19 ENST00000490465.1
RP11-639B1.1
RP11-639B1.1
chr10_+_18549645 0.19 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr16_-_28621312 0.19 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_155006300 0.19 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr7_-_24797546 0.19 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr19_+_10362882 0.19 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr2_+_196313239 0.19 ENST00000413290.1
AC064834.1
AC064834.1
chrX_-_48824793 0.18 ENST00000376477.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_231004220 0.18 ENST00000366663.5
C1orf198
chromosome 1 open reading frame 198
chr10_+_6779326 0.18 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr12_-_122985067 0.18 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chrX_-_77225135 0.18 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr5_-_96478466 0.17 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr19_+_48949030 0.17 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr9_+_130911770 0.17 ENST00000372998.1
LCN2
lipocalin 2
chr2_+_208423840 0.17 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr15_-_101835414 0.17 ENST00000254193.6
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr14_+_74034310 0.16 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr3_-_151034734 0.16 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr16_-_31085514 0.16 ENST00000300849.4
ZNF668
zinc finger protein 668
chr11_-_26593649 0.16 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr7_+_5919458 0.16 ENST00000416608.1
OCM
oncomodulin
chr12_+_7014126 0.16 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr11_-_26593677 0.16 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr10_+_53806501 0.16 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr4_+_110736659 0.15 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr2_+_29336855 0.15 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chrX_-_39923656 0.15 ENST00000413905.1
BCOR
BCL6 corepressor
chr17_-_73901494 0.15 ENST00000309352.3
MRPL38
mitochondrial ribosomal protein L38
chr7_+_129015484 0.15 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_-_51796226 0.15 ENST00000451380.1
ENST00000371747.3
ENST00000439482.1
TTC39A
tetratricopeptide repeat domain 39A
chr2_+_168675182 0.14 ENST00000305861.1
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr16_-_11036300 0.14 ENST00000331808.4
DEXI
Dexi homolog (mouse)
chr19_-_6737576 0.14 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr14_+_22320634 0.14 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr2_-_89160770 0.14 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr11_-_104817919 0.14 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr20_-_5485166 0.14 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr7_+_99202003 0.14 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr6_+_26045603 0.13 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr17_-_40337470 0.13 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr19_-_46088068 0.12 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr10_-_27529486 0.12 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr17_-_8770956 0.12 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr9_+_130911723 0.12 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr4_+_113568207 0.12 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr4_-_164534657 0.11 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_121944491 0.11 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr16_+_31366536 0.11 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_+_67219867 0.11 ENST00000438189.2
CABP4
calcium binding protein 4
chr3_+_114012819 0.11 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr6_-_82957433 0.11 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_88125471 0.11 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr14_+_57671888 0.11 ENST00000391612.1
AL391152.1
AL391152.1
chr7_-_122339162 0.10 ENST00000340112.2
RNF133
ring finger protein 133
chr4_-_111563076 0.10 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr21_+_31768348 0.10 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr12_-_5352315 0.10 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr3_-_151047327 0.10 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr17_-_62208169 0.10 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr12_+_22778116 0.10 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr8_-_623547 0.10 ENST00000522893.1
ERICH1
glutamate-rich 1
chrX_-_21676442 0.10 ENST00000379499.2
KLHL34
kelch-like family member 34
chr2_+_234545148 0.10 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_-_207226313 0.10 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr1_-_13390765 0.09 ENST00000357367.2
PRAMEF8
PRAME family member 8
chr6_+_149721495 0.09 ENST00000326669.4
SUMO4
small ubiquitin-like modifier 4
chr12_-_6740802 0.09 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chrX_+_41548259 0.09 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr2_+_89184868 0.09 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr12_-_117175819 0.09 ENST00000261318.3
ENST00000536380.1
C12orf49
chromosome 12 open reading frame 49
chr5_+_115177178 0.09 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr19_-_6424783 0.09 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr6_+_45296391 0.09 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr15_+_78830023 0.08 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr11_-_96076334 0.08 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_-_146040968 0.08 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr12_+_55248289 0.08 ENST00000308796.6
MUCL1
mucin-like 1
chr5_+_129083772 0.08 ENST00000564719.1
KIAA1024L
KIAA1024-like
chrX_+_102024075 0.08 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr12_-_123187890 0.08 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chrX_+_41548220 0.08 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr2_+_113816215 0.08 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr4_-_8873531 0.08 ENST00000400677.3
HMX1
H6 family homeobox 1
chr8_+_50824233 0.08 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr12_-_123201337 0.08 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr2_-_113810444 0.08 ENST00000259213.4
ENST00000327407.2
IL36B
interleukin 36, beta
chr5_+_55149150 0.08 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr16_+_31724552 0.07 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr11_-_119991589 0.07 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr1_+_197237352 0.07 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chr5_-_32444828 0.07 ENST00000265069.8
ZFR
zinc finger RNA binding protein
chr5_+_140019004 0.07 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
TMCO6
transmembrane and coiled-coil domains 6
chrX_+_83116142 0.07 ENST00000329312.4
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr4_-_138453559 0.07 ENST00000511115.1
PCDH18
protocadherin 18
chr2_+_228736321 0.07 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr9_+_135937365 0.07 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr18_+_268148 0.07 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr1_+_202317815 0.07 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr1_+_156030937 0.07 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr14_-_24711865 0.07 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_78753496 0.07 ENST00000548512.1
RP11-38F22.1
RP11-38F22.1
chr9_+_124329336 0.07 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr15_+_84841242 0.07 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr9_-_100707116 0.07 ENST00000259456.3
HEMGN
hemogen
chr14_-_24711806 0.07 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr11_+_63273811 0.07 ENST00000340246.5
LGALS12
lectin, galactoside-binding, soluble, 12
chr6_+_34204642 0.07 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr16_+_6069072 0.06 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_169887827 0.06 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr16_-_66864806 0.06 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr2_+_197577841 0.06 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chrX_+_106045891 0.06 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr4_-_100212132 0.06 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_+_26204825 0.06 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr1_+_207226574 0.06 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_-_119182523 0.06 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr6_-_119256279 0.06 ENST00000316068.3
MCM9
minichromosome maintenance complex component 9
chr14_+_32798462 0.06 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_144173162 0.06 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr3_-_126327398 0.06 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr2_-_3606206 0.06 ENST00000315212.3
RNASEH1
ribonuclease H1
chr1_+_202317855 0.06 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr4_-_52883786 0.06 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr5_-_108063949 0.05 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr6_+_36562132 0.05 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chrX_+_135730373 0.05 ENST00000370628.2
CD40LG
CD40 ligand
chr6_-_133035185 0.05 ENST00000367928.4
VNN1
vanin 1
chr11_-_95522907 0.05 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr10_-_135379132 0.05 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr5_+_140019079 0.05 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr4_+_40198527 0.05 ENST00000381799.5
RHOH
ras homolog family member H
chr2_+_166095898 0.05 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0035419 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.8 GO:0014877 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline