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Inflammatory response time course, HUVEC (Wada et al., 2009)
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Results for HOXB6_PRRX2
Z-value: 2.19
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Transcription factors associated with HOXB6_PRRX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXB6
|
ENSG00000108511.8 | homeobox B6 |
|
PRRX2
|
ENSG00000167157.9 | paired related homeobox 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB6 | hg19_v2_chr17_-_46682321_46682362 | -0.42 | 3.9e-02 | Click! |
| PRRX2 | hg19_v2_chr9_+_132427883_132427951 | -0.40 | 4.9e-02 | Click! |
Activity profile of HOXB6_PRRX2 motif
Sorted Z-values of HOXB6_PRRX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_2159850 | 19.90 |
ENST00000416751.1
|
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr1_+_61869748 | 18.55 |
ENST00000357977.5
|
NFIA
|
nuclear factor I/A |
| chr13_-_72441315 | 13.79 |
ENST00000305425.4
ENST00000313174.7 ENST00000354591.4 |
DACH1
|
dachshund homolog 1 (Drosophila) |
| chr7_-_27183263 | 13.76 |
ENST00000222726.3
|
HOXA5
|
homeobox A5 |
| chr4_+_41614909 | 13.36 |
ENST00000509454.1
ENST00000396595.3 ENST00000381753.4 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chr1_+_84630053 | 13.31 |
ENST00000394838.2
ENST00000370682.3 ENST00000432111.1 |
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr5_-_88179302 | 13.28 |
ENST00000504921.2
|
MEF2C
|
myocyte enhancer factor 2C |
| chr9_-_14308004 | 13.15 |
ENST00000493697.1
|
NFIB
|
nuclear factor I/B |
| chr9_+_2158485 | 12.98 |
ENST00000417599.1
ENST00000382185.1 ENST00000382183.1 |
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr9_+_2158443 | 12.42 |
ENST00000302401.3
ENST00000324954.5 ENST00000423555.1 ENST00000382186.1 |
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr4_+_41614720 | 12.19 |
ENST00000509277.1
|
LIMCH1
|
LIM and calponin homology domains 1 |
| chr14_-_54423529 | 11.92 |
ENST00000245451.4
ENST00000559087.1 |
BMP4
|
bone morphogenetic protein 4 |
| chr4_-_186877806 | 10.32 |
ENST00000355634.5
|
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr1_+_84630645 | 10.28 |
ENST00000394839.2
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr9_+_2015335 | 10.00 |
ENST00000349721.2
ENST00000357248.2 ENST00000450198.1 |
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr8_-_93107443 | 9.88 |
ENST00000360348.2
ENST00000520428.1 ENST00000518992.1 ENST00000520556.1 ENST00000518317.1 ENST00000521319.1 ENST00000521375.1 ENST00000518449.1 |
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr14_-_92413353 | 9.63 |
ENST00000556154.1
|
FBLN5
|
fibulin 5 |
| chr18_+_72922710 | 8.37 |
ENST00000322038.5
|
TSHZ1
|
teashirt zinc finger homeobox 1 |
| chr6_-_76203345 | 8.27 |
ENST00000393004.2
|
FILIP1
|
filamin A interacting protein 1 |
| chr5_-_88119580 | 8.16 |
ENST00000539796.1
|
MEF2C
|
myocyte enhancer factor 2C |
| chr18_-_53089723 | 7.75 |
ENST00000561992.1
ENST00000562512.2 |
TCF4
|
transcription factor 4 |
| chr8_-_80993010 | 7.56 |
ENST00000537855.1
ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3 |
TPD52
|
tumor protein D52 |
| chr4_-_186877502 | 7.56 |
ENST00000431902.1
ENST00000284776.7 ENST00000415274.1 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr18_-_22932080 | 7.10 |
ENST00000584787.1
ENST00000361524.3 ENST00000538137.2 |
ZNF521
|
zinc finger protein 521 |
| chr9_-_13165457 | 7.03 |
ENST00000542239.1
ENST00000538841.1 ENST00000433359.2 |
MPDZ
|
multiple PDZ domain protein |
| chr1_+_61547405 | 6.95 |
ENST00000371189.4
|
NFIA
|
nuclear factor I/A |
| chr14_-_92413727 | 6.91 |
ENST00000267620.10
|
FBLN5
|
fibulin 5 |
| chr11_-_33913708 | 6.75 |
ENST00000257818.2
|
LMO2
|
LIM domain only 2 (rhombotin-like 1) |
| chr6_-_76203454 | 5.97 |
ENST00000237172.7
|
FILIP1
|
filamin A interacting protein 1 |
| chr17_-_46688334 | 5.97 |
ENST00000239165.7
|
HOXB7
|
homeobox B7 |
| chr4_-_186733363 | 5.87 |
ENST00000393523.2
ENST00000393528.3 ENST00000449407.2 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr9_-_3469181 | 5.78 |
ENST00000366116.2
|
AL365202.1
|
Uncharacterized protein |
| chr9_-_124989804 | 5.62 |
ENST00000373755.2
ENST00000373754.2 |
LHX6
|
LIM homeobox 6 |
| chr3_-_18466026 | 5.56 |
ENST00000417717.2
|
SATB1
|
SATB homeobox 1 |
| chr2_-_183291741 | 5.53 |
ENST00000351439.5
ENST00000409365.1 |
PDE1A
|
phosphodiesterase 1A, calmodulin-dependent |
| chr2_+_66662510 | 5.48 |
ENST00000272369.9
ENST00000407092.2 |
MEIS1
|
Meis homeobox 1 |
| chr13_-_45010939 | 5.43 |
ENST00000261489.2
|
TSC22D1
|
TSC22 domain family, member 1 |
| chr1_+_61548225 | 5.43 |
ENST00000371187.3
|
NFIA
|
nuclear factor I/A |
| chr2_+_66662690 | 5.34 |
ENST00000488550.1
|
MEIS1
|
Meis homeobox 1 |
| chr8_-_93107696 | 5.21 |
ENST00000436581.2
ENST00000520583.1 ENST00000519061.1 |
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr1_+_100111580 | 5.11 |
ENST00000605497.1
|
PALMD
|
palmdelphin |
| chr7_-_27205136 | 5.03 |
ENST00000396345.1
ENST00000343483.6 |
HOXA9
|
homeobox A9 |
| chr18_-_52989217 | 5.00 |
ENST00000570287.2
|
TCF4
|
transcription factor 4 |
| chr1_+_100111479 | 4.89 |
ENST00000263174.4
|
PALMD
|
palmdelphin |
| chr13_+_36050881 | 4.86 |
ENST00000537702.1
|
NBEA
|
neurobeachin |
| chr9_-_14314518 | 4.80 |
ENST00000397581.2
|
NFIB
|
nuclear factor I/B |
| chr21_+_17443434 | 4.80 |
ENST00000400178.2
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr9_-_14314566 | 4.77 |
ENST00000397579.2
|
NFIB
|
nuclear factor I/B |
| chr21_+_17909594 | 4.71 |
ENST00000441820.1
ENST00000602280.1 |
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr1_+_61330931 | 4.71 |
ENST00000371191.1
|
NFIA
|
nuclear factor I/A |
| chr5_-_111092930 | 4.64 |
ENST00000257435.7
|
NREP
|
neuronal regeneration related protein |
| chrX_-_19688475 | 4.60 |
ENST00000541422.1
|
SH3KBP1
|
SH3-domain kinase binding protein 1 |
| chr6_+_136172820 | 4.56 |
ENST00000308191.6
|
PDE7B
|
phosphodiesterase 7B |
| chr6_-_76072719 | 4.53 |
ENST00000370020.1
|
FILIP1
|
filamin A interacting protein 1 |
| chr11_+_125034586 | 4.49 |
ENST00000298282.9
|
PKNOX2
|
PBX/knotted 1 homeobox 2 |
| chr15_+_57511609 | 4.44 |
ENST00000543579.1
ENST00000537840.1 ENST00000343827.3 |
TCF12
|
transcription factor 12 |
| chr2_+_191792376 | 4.44 |
ENST00000409428.1
ENST00000409215.1 |
GLS
|
glutaminase |
| chr3_-_27764190 | 4.33 |
ENST00000537516.1
|
EOMES
|
eomesodermin |
| chr21_+_17443521 | 4.30 |
ENST00000456342.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr3_-_18480260 | 4.30 |
ENST00000454909.2
|
SATB1
|
SATB homeobox 1 |
| chr3_-_114477787 | 4.23 |
ENST00000464560.1
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr21_-_40033618 | 4.18 |
ENST00000417133.2
ENST00000398910.1 ENST00000442448.1 |
ERG
|
v-ets avian erythroblastosis virus E26 oncogene homolog |
| chr6_-_32157947 | 4.06 |
ENST00000375050.4
|
PBX2
|
pre-B-cell leukemia homeobox 2 |
| chr1_+_61548374 | 4.04 |
ENST00000485903.2
ENST00000371185.2 ENST00000371184.2 |
NFIA
|
nuclear factor I/A |
| chr17_+_42634844 | 4.04 |
ENST00000315323.3
|
FZD2
|
frizzled family receptor 2 |
| chr4_-_138453606 | 4.03 |
ENST00000412923.2
ENST00000344876.4 ENST00000507846.1 ENST00000510305.1 |
PCDH18
|
protocadherin 18 |
| chr3_-_65583561 | 4.02 |
ENST00000460329.2
|
MAGI1
|
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| chrX_+_135251783 | 4.01 |
ENST00000394153.2
|
FHL1
|
four and a half LIM domains 1 |
| chr5_-_112630598 | 3.97 |
ENST00000302475.4
|
MCC
|
mutated in colorectal cancers |
| chr5_-_111093167 | 3.97 |
ENST00000446294.2
ENST00000419114.2 |
NREP
|
neuronal regeneration related protein |
| chr12_+_79258547 | 3.92 |
ENST00000457153.2
|
SYT1
|
synaptotagmin I |
| chr12_+_79258444 | 3.91 |
ENST00000261205.4
|
SYT1
|
synaptotagmin I |
| chr1_+_84630367 | 3.89 |
ENST00000370680.1
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr7_+_102553430 | 3.88 |
ENST00000339431.4
ENST00000249377.4 |
LRRC17
|
leucine rich repeat containing 17 |
| chr3_-_114477962 | 3.82 |
ENST00000471418.1
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr6_+_130339710 | 3.73 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chr3_+_141105705 | 3.64 |
ENST00000513258.1
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr4_-_16900242 | 3.64 |
ENST00000502640.1
ENST00000506732.1 |
LDB2
|
LIM domain binding 2 |
| chrX_-_20236970 | 3.64 |
ENST00000379548.4
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| chr18_-_52989525 | 3.62 |
ENST00000457482.3
|
TCF4
|
transcription factor 4 |
| chr2_-_165424973 | 3.60 |
ENST00000543549.1
|
GRB14
|
growth factor receptor-bound protein 14 |
| chrX_+_135251835 | 3.60 |
ENST00000456445.1
|
FHL1
|
four and a half LIM domains 1 |
| chr15_+_96869165 | 3.55 |
ENST00000421109.2
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
| chr5_-_111093759 | 3.50 |
ENST00000509979.1
ENST00000513100.1 ENST00000508161.1 ENST00000455559.2 |
NREP
|
neuronal regeneration related protein |
| chrX_+_28605516 | 3.42 |
ENST00000378993.1
|
IL1RAPL1
|
interleukin 1 receptor accessory protein-like 1 |
| chr16_+_8806800 | 3.41 |
ENST00000561870.1
ENST00000396600.2 |
ABAT
|
4-aminobutyrate aminotransferase |
| chr13_+_78315466 | 3.40 |
ENST00000314070.5
ENST00000462234.1 |
SLAIN1
|
SLAIN motif family, member 1 |
| chrX_+_135279179 | 3.38 |
ENST00000370676.3
|
FHL1
|
four and a half LIM domains 1 |
| chrX_-_117119243 | 3.31 |
ENST00000539496.1
ENST00000469946.1 |
KLHL13
|
kelch-like family member 13 |
| chr4_-_99578776 | 3.29 |
ENST00000515287.1
|
TSPAN5
|
tetraspanin 5 |
| chr18_-_53070913 | 3.25 |
ENST00000568186.1
ENST00000564228.1 |
TCF4
|
transcription factor 4 |
| chr10_+_35456444 | 3.23 |
ENST00000361599.4
|
CREM
|
cAMP responsive element modulator |
| chrX_+_135278908 | 3.22 |
ENST00000539015.1
ENST00000370683.1 |
FHL1
|
four and a half LIM domains 1 |
| chr14_+_61654271 | 3.22 |
ENST00000555185.1
ENST00000557294.1 ENST00000556778.1 |
PRKCH
|
protein kinase C, eta |
| chr14_-_92414055 | 3.20 |
ENST00000342058.4
|
FBLN5
|
fibulin 5 |
| chr11_-_27723158 | 3.20 |
ENST00000395980.2
|
BDNF
|
brain-derived neurotrophic factor |
| chr20_+_11898507 | 3.15 |
ENST00000378226.2
|
BTBD3
|
BTB (POZ) domain containing 3 |
| chr4_-_101439242 | 3.12 |
ENST00000296420.4
|
EMCN
|
endomucin |
| chr3_+_25469802 | 3.11 |
ENST00000330688.4
|
RARB
|
retinoic acid receptor, beta |
| chr9_+_82188077 | 3.10 |
ENST00000425506.1
|
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr6_+_143929307 | 3.09 |
ENST00000427704.2
ENST00000305766.6 |
PHACTR2
|
phosphatase and actin regulator 2 |
| chr3_-_64211112 | 3.06 |
ENST00000295902.6
|
PRICKLE2
|
prickle homolog 2 (Drosophila) |
| chrX_+_135252050 | 2.99 |
ENST00000449474.1
ENST00000345434.3 |
FHL1
|
four and a half LIM domains 1 |
| chr9_-_14180778 | 2.98 |
ENST00000380924.1
ENST00000543693.1 |
NFIB
|
nuclear factor I/B |
| chr15_+_66994561 | 2.94 |
ENST00000288840.5
|
SMAD6
|
SMAD family member 6 |
| chr10_-_116444371 | 2.91 |
ENST00000533213.2
ENST00000369252.4 |
ABLIM1
|
actin binding LIM protein 1 |
| chr4_-_99578789 | 2.88 |
ENST00000511651.1
ENST00000505184.1 |
TSPAN5
|
tetraspanin 5 |
| chr9_+_75263565 | 2.88 |
ENST00000396237.3
|
TMC1
|
transmembrane channel-like 1 |
| chr9_-_13175823 | 2.84 |
ENST00000545857.1
|
MPDZ
|
multiple PDZ domain protein |
| chr9_-_20622478 | 2.84 |
ENST00000355930.6
ENST00000380338.4 |
MLLT3
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| chr3_+_141106458 | 2.79 |
ENST00000509883.1
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr6_+_144904334 | 2.78 |
ENST00000367526.4
|
UTRN
|
utrophin |
| chr21_+_17961006 | 2.77 |
ENST00000602323.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr10_+_94594351 | 2.76 |
ENST00000371552.4
|
EXOC6
|
exocyst complex component 6 |
| chr4_+_170581213 | 2.71 |
ENST00000507875.1
|
CLCN3
|
chloride channel, voltage-sensitive 3 |
| chr21_+_17792672 | 2.71 |
ENST00000602620.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr20_-_45985172 | 2.66 |
ENST00000536340.1
|
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chrX_+_10031499 | 2.64 |
ENST00000454666.1
|
WWC3
|
WWC family member 3 |
| chr1_+_78470530 | 2.63 |
ENST00000370763.5
|
DNAJB4
|
DnaJ (Hsp40) homolog, subfamily B, member 4 |
| chr11_-_31531121 | 2.63 |
ENST00000532287.1
ENST00000526776.1 ENST00000534812.1 ENST00000529749.1 ENST00000278200.1 ENST00000530023.1 ENST00000533642.1 |
IMMP1L
|
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) |
| chr22_-_32860427 | 2.56 |
ENST00000534972.1
ENST00000397450.1 ENST00000397452.1 |
BPIFC
|
BPI fold containing family C |
| chr2_-_183387430 | 2.53 |
ENST00000410103.1
|
PDE1A
|
phosphodiesterase 1A, calmodulin-dependent |
| chr1_+_61547894 | 2.50 |
ENST00000403491.3
|
NFIA
|
nuclear factor I/A |
| chr2_-_99279928 | 2.49 |
ENST00000414521.2
|
MGAT4A
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| chr2_-_177502659 | 2.48 |
ENST00000295549.4
|
AC017048.3
|
long intergenic non-protein coding RNA 1116 |
| chr13_+_58206655 | 2.48 |
ENST00000377918.3
|
PCDH17
|
protocadherin 17 |
| chr13_-_67802549 | 2.48 |
ENST00000328454.5
ENST00000377865.2 |
PCDH9
|
protocadherin 9 |
| chr1_-_68698197 | 2.47 |
ENST00000370973.2
ENST00000370971.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr4_-_101439148 | 2.47 |
ENST00000511970.1
ENST00000502569.1 ENST00000305864.3 |
EMCN
|
endomucin |
| chr18_+_42260861 | 2.47 |
ENST00000282030.5
|
SETBP1
|
SET binding protein 1 |
| chr4_-_159080806 | 2.44 |
ENST00000590648.1
|
FAM198B
|
family with sequence similarity 198, member B |
| chrX_-_117107542 | 2.42 |
ENST00000371878.1
|
KLHL13
|
kelch-like family member 13 |
| chr15_+_96876340 | 2.42 |
ENST00000453270.2
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
| chr8_-_93107827 | 2.40 |
ENST00000520724.1
ENST00000518844.1 |
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr2_+_176994408 | 2.38 |
ENST00000429017.1
ENST00000313173.4 ENST00000544999.1 |
HOXD8
|
homeobox D8 |
| chr12_-_58212487 | 2.38 |
ENST00000549994.1
|
AVIL
|
advillin |
| chr1_+_82266053 | 2.37 |
ENST00000370715.1
ENST00000370713.1 ENST00000319517.6 ENST00000370717.2 ENST00000394879.1 ENST00000271029.4 ENST00000335786.5 |
LPHN2
|
latrophilin 2 |
| chr3_+_25469724 | 2.36 |
ENST00000437042.2
|
RARB
|
retinoic acid receptor, beta |
| chr5_-_88178964 | 2.35 |
ENST00000513252.1
ENST00000508569.1 ENST00000510942.1 ENST00000506554.1 |
MEF2C
|
myocyte enhancer factor 2C |
| chr19_+_2476116 | 2.34 |
ENST00000215631.4
ENST00000587345.1 |
GADD45B
|
growth arrest and DNA-damage-inducible, beta |
| chr18_-_53069419 | 2.33 |
ENST00000570177.2
|
TCF4
|
transcription factor 4 |
| chr20_-_45985464 | 2.31 |
ENST00000458360.2
ENST00000262975.4 |
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr7_-_14026123 | 2.30 |
ENST00000420159.2
ENST00000399357.3 ENST00000403527.1 |
ETV1
|
ets variant 1 |
| chr6_+_155537771 | 2.30 |
ENST00000275246.7
|
TIAM2
|
T-cell lymphoma invasion and metastasis 2 |
| chr20_-_45985414 | 2.29 |
ENST00000461685.1
ENST00000372023.3 ENST00000540497.1 ENST00000435836.1 ENST00000471951.2 ENST00000352431.2 ENST00000396281.4 ENST00000355972.4 ENST00000360911.3 |
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr21_-_39870339 | 2.27 |
ENST00000429727.2
ENST00000398905.1 ENST00000398907.1 ENST00000453032.2 ENST00000288319.7 |
ERG
|
v-ets avian erythroblastosis virus E26 oncogene homolog |
| chrX_-_117107680 | 2.26 |
ENST00000447671.2
ENST00000262820.3 |
KLHL13
|
kelch-like family member 13 |
| chr5_-_111092873 | 2.25 |
ENST00000509025.1
ENST00000515855.1 |
NREP
|
neuronal regeneration related protein |
| chr2_+_120687335 | 2.24 |
ENST00000544261.1
|
PTPN4
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| chr1_+_168250194 | 2.22 |
ENST00000367821.3
|
TBX19
|
T-box 19 |
| chr2_+_176987088 | 2.20 |
ENST00000249499.6
|
HOXD9
|
homeobox D9 |
| chr7_-_27213893 | 2.19 |
ENST00000283921.4
|
HOXA10
|
homeobox A10 |
| chr8_-_17533838 | 2.18 |
ENST00000400046.1
|
MTUS1
|
microtubule associated tumor suppressor 1 |
| chr2_+_66666432 | 2.15 |
ENST00000495021.2
|
MEIS1
|
Meis homeobox 1 |
| chr12_+_93965451 | 2.13 |
ENST00000548537.1
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chr5_-_111091948 | 2.13 |
ENST00000447165.2
|
NREP
|
neuronal regeneration related protein |
| chr3_-_18466787 | 2.12 |
ENST00000338745.6
ENST00000450898.1 |
SATB1
|
SATB homeobox 1 |
| chr20_-_45981138 | 2.11 |
ENST00000446994.2
|
ZMYND8
|
zinc finger, MYND-type containing 8 |
| chr8_-_93029865 | 2.11 |
ENST00000422361.2
|
RUNX1T1
|
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| chr1_+_164528866 | 2.10 |
ENST00000420696.2
|
PBX1
|
pre-B-cell leukemia homeobox 1 |
| chr10_-_21786179 | 2.10 |
ENST00000377113.5
|
CASC10
|
cancer susceptibility candidate 10 |
| chr12_-_71031220 | 2.10 |
ENST00000334414.6
|
PTPRB
|
protein tyrosine phosphatase, receptor type, B |
| chr12_-_71031185 | 2.08 |
ENST00000548122.1
ENST00000551525.1 ENST00000550358.1 |
PTPRB
|
protein tyrosine phosphatase, receptor type, B |
| chr1_-_68698222 | 2.08 |
ENST00000370976.3
ENST00000354777.2 ENST00000262348.4 ENST00000540432.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr11_+_101983176 | 2.06 |
ENST00000524575.1
|
YAP1
|
Yes-associated protein 1 |
| chr2_+_33359646 | 2.05 |
ENST00000390003.4
ENST00000418533.2 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr2_+_33359687 | 2.04 |
ENST00000402934.1
ENST00000404525.1 ENST00000407925.1 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr12_+_32655048 | 2.04 |
ENST00000427716.2
ENST00000266482.3 |
FGD4
|
FYVE, RhoGEF and PH domain containing 4 |
| chr11_+_92085262 | 2.02 |
ENST00000298047.6
ENST00000409404.2 ENST00000541502.1 |
FAT3
|
FAT atypical cadherin 3 |
| chr18_-_500692 | 2.01 |
ENST00000400256.3
|
COLEC12
|
collectin sub-family member 12 |
| chr3_+_141105235 | 2.01 |
ENST00000503809.1
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr6_+_15246501 | 2.01 |
ENST00000341776.2
|
JARID2
|
jumonji, AT rich interactive domain 2 |
| chr13_+_78315295 | 2.01 |
ENST00000351546.3
|
SLAIN1
|
SLAIN motif family, member 1 |
| chr12_+_79439405 | 1.98 |
ENST00000552744.1
|
SYT1
|
synaptotagmin I |
| chr4_+_88529681 | 1.98 |
ENST00000399271.1
|
DSPP
|
dentin sialophosphoprotein |
| chr4_+_129730947 | 1.98 |
ENST00000452328.2
ENST00000504089.1 |
PHF17
|
jade family PHD finger 1 |
| chr12_+_93965609 | 1.97 |
ENST00000549887.1
ENST00000551556.1 |
SOCS2
|
suppressor of cytokine signaling 2 |
| chr13_-_99667960 | 1.97 |
ENST00000448493.2
|
DOCK9
|
dedicator of cytokinesis 9 |
| chr2_+_132479948 | 1.97 |
ENST00000355171.4
|
C2orf27A
|
chromosome 2 open reading frame 27A |
| chr15_+_96875657 | 1.96 |
ENST00000559679.1
ENST00000394171.2 |
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
| chr6_+_153019023 | 1.95 |
ENST00000367245.5
ENST00000529453.1 |
MYCT1
|
myc target 1 |
| chr11_+_123396528 | 1.93 |
ENST00000322282.7
ENST00000529750.1 |
GRAMD1B
|
GRAM domain containing 1B |
| chr8_+_42873548 | 1.92 |
ENST00000533338.1
ENST00000534420.1 |
HOOK3
RP11-598P20.5
|
hook microtubule-tethering protein 3 Uncharacterized protein |
| chr2_+_28618532 | 1.91 |
ENST00000545753.1
|
FOSL2
|
FOS-like antigen 2 |
| chr2_+_210444748 | 1.91 |
ENST00000392194.1
|
MAP2
|
microtubule-associated protein 2 |
| chr2_+_177015950 | 1.89 |
ENST00000306324.3
|
HOXD4
|
homeobox D4 |
| chr4_-_25865159 | 1.89 |
ENST00000502949.1
ENST00000264868.5 ENST00000513691.1 ENST00000514872.1 |
SEL1L3
|
sel-1 suppressor of lin-12-like 3 (C. elegans) |
| chr4_+_30723003 | 1.89 |
ENST00000543491.1
|
PCDH7
|
protocadherin 7 |
| chr11_-_69633792 | 1.88 |
ENST00000334134.2
|
FGF3
|
fibroblast growth factor 3 |
| chr1_-_201140673 | 1.88 |
ENST00000367333.2
|
TMEM9
|
transmembrane protein 9 |
| chr21_+_17442799 | 1.87 |
ENST00000602580.1
ENST00000458468.1 ENST00000602935.1 |
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr3_+_152017924 | 1.87 |
ENST00000465907.2
ENST00000492948.1 ENST00000485509.1 ENST00000464596.1 |
MBNL1
|
muscleblind-like splicing regulator 1 |
| chr12_+_96588279 | 1.86 |
ENST00000552142.1
|
ELK3
|
ELK3, ETS-domain protein (SRF accessory protein 2) |
| chr1_+_87797351 | 1.85 |
ENST00000370542.1
|
LMO4
|
LIM domain only 4 |
| chr17_-_46716647 | 1.85 |
ENST00000608940.1
|
RP11-357H14.17
|
RP11-357H14.17 |
| chr5_-_90679145 | 1.85 |
ENST00000265138.3
|
ARRDC3
|
arrestin domain containing 3 |
| chr6_+_153019069 | 1.81 |
ENST00000532295.1
|
MYCT1
|
myc target 1 |
| chr1_+_81771806 | 1.81 |
ENST00000370721.1
ENST00000370727.1 ENST00000370725.1 ENST00000370723.1 ENST00000370728.1 ENST00000370730.1 |
LPHN2
|
latrophilin 2 |
| chr18_-_53177984 | 1.80 |
ENST00000543082.1
|
TCF4
|
transcription factor 4 |
| chr16_-_67517716 | 1.79 |
ENST00000290953.2
|
AGRP
|
agouti related protein homolog (mouse) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB6_PRRX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.3 | 25.3 | GO:0003185 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 4.6 | 13.8 | GO:0060435 | bronchiole development(GO:0060435) |
| 4.0 | 11.9 | GO:0048390 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 3.9 | 27.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 3.7 | 25.7 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 3.3 | 9.8 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 2.0 | 6.0 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 2.0 | 7.9 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.8 | 11.0 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 1.8 | 9.0 | GO:0060023 | soft palate development(GO:0060023) |
| 1.7 | 13.3 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 1.7 | 41.3 | GO:0072189 | ureter development(GO:0072189) |
| 1.3 | 17.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 1.1 | 4.6 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.1 | 6.5 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
| 1.1 | 3.2 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.9 | 4.4 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.9 | 13.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.9 | 3.4 | GO:1904450 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.8 | 2.5 | GO:0035284 | rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.8 | 3.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.7 | 23.6 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.7 | 4.0 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
| 0.6 | 13.6 | GO:0055022 | negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117) |
| 0.6 | 11.6 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.6 | 4.4 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.6 | 5.5 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.6 | 6.0 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.6 | 3.5 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.6 | 1.1 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.5 | 2.1 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.5 | 2.1 | GO:0046373 | arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373) |
| 0.5 | 1.4 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.4 | 0.9 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.4 | 2.6 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.4 | 1.3 | GO:0060823 | canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) |
| 0.4 | 1.2 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.4 | 5.4 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.4 | 1.6 | GO:0090107 | aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.4 | 2.0 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.4 | 1.2 | GO:0090425 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.4 | 1.5 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.4 | 22.0 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.4 | 2.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.3 | 1.4 | GO:0018032 | protein amidation(GO:0018032) |
| 0.3 | 3.8 | GO:0003183 | mitral valve morphogenesis(GO:0003183) |
| 0.3 | 3.5 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.3 | 2.6 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 2.6 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.3 | 57.2 | GO:0007286 | spermatid development(GO:0007286) |
| 0.3 | 3.7 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.3 | 6.2 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.3 | 1.5 | GO:1905040 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.3 | 1.2 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 0.3 | 0.9 | GO:0003363 | lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816) |
| 0.3 | 0.9 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.3 | 2.1 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.3 | 5.9 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.3 | 3.1 | GO:0007379 | segment specification(GO:0007379) |
| 0.3 | 1.4 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.3 | 1.4 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.3 | 1.1 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.3 | 1.8 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.3 | 3.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.3 | 8.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.3 | 1.6 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.3 | 1.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.3 | 3.8 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
| 0.3 | 0.3 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.2 | 0.7 | GO:0090325 | regulation of locomotion involved in locomotory behavior(GO:0090325) |
| 0.2 | 0.7 | GO:0046005 | positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005) |
| 0.2 | 15.8 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.2 | 11.6 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 1.1 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.2 | 1.3 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.2 | 0.4 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.2 | 0.6 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.2 | 0.8 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.2 | 1.0 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.2 | 1.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 2.9 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.2 | 1.3 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.2 | 1.1 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.2 | 1.1 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.2 | 0.4 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.2 | 1.9 | GO:0055026 | negative regulation of cardiac muscle tissue development(GO:0055026) |
| 0.2 | 0.2 | GO:0033092 | positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) |
| 0.2 | 1.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 1.8 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.2 | 0.5 | GO:0016999 | antibiotic metabolic process(GO:0016999) cellular chloride ion homeostasis(GO:0030644) detoxification of mercury ion(GO:0050787) |
| 0.2 | 2.3 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.2 | 0.7 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.2 | 0.5 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 0.2 | 1.0 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.2 | 0.5 | GO:0038188 | cholecystokinin signaling pathway(GO:0038188) |
| 0.2 | 2.0 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.2 | 1.5 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.2 | 0.7 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.2 | 3.9 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.2 | 0.6 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
| 0.2 | 1.8 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.2 | 0.3 | GO:0061009 | common bile duct development(GO:0061009) |
| 0.1 | 1.0 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.7 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.1 | 0.3 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.1 | 2.0 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 0.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.1 | 1.1 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034) |
| 0.1 | 3.5 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.1 | 0.9 | GO:2000741 | asymmetric neuroblast division(GO:0055059) positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.1 | 0.7 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.1 | 1.6 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 0.5 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.1 | 6.7 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 1.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.5 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.1 | 0.4 | GO:0018315 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.1 | 0.6 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.1 | 0.4 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.1 | 0.5 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 0.7 | GO:0045683 | negative regulation of epidermis development(GO:0045683) |
| 0.1 | 1.9 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 0.4 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.1 | 0.7 | GO:0060751 | epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) |
| 0.1 | 0.6 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.9 | GO:0030903 | notochord development(GO:0030903) |
| 0.1 | 28.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 0.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 1.7 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
| 0.1 | 0.4 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 0.1 | 0.3 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.1 | 0.6 | GO:2000334 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.1 | 0.8 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 1.6 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 1.4 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.9 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.1 | 0.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.1 | 1.2 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.1 | 0.3 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 3.3 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 1.6 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 0.4 | GO:0008582 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.1 | 1.9 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.1 | 0.8 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.6 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 1.5 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 4.1 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 0.8 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.1 | 0.5 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.4 | GO:0048690 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.1 | 0.4 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.1 | 1.1 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.1 | 0.6 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.1 | 0.4 | GO:0046116 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.1 | 0.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.1 | 0.1 | GO:0035711 | T-helper 1 cell activation(GO:0035711) |
| 0.1 | 6.1 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.1 | 0.5 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 3.2 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.1 | 2.2 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 2.7 | GO:0016577 | histone demethylation(GO:0016577) |
| 0.1 | 0.1 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.1 | 0.8 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
| 0.1 | 0.8 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.1 | 1.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 0.3 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.1 | 2.0 | GO:0072662 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.1 | 0.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.1 | 1.0 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.1 | 0.9 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.1 | 0.7 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 1.1 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 2.4 | GO:0045920 | negative regulation of exocytosis(GO:0045920) |
| 0.1 | 0.5 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.1 | 0.3 | GO:0050955 | thermoception(GO:0050955) |
| 0.1 | 1.2 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.1 | 0.1 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.1 | 0.9 | GO:0051412 | response to corticosterone(GO:0051412) |
| 0.1 | 0.5 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 1.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.1 | 7.2 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.1 | 2.0 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 0.7 | GO:0071787 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.2 | GO:0060591 | chondroblast differentiation(GO:0060591) |
| 0.1 | 0.6 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.1 | 0.1 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.1 | 0.3 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.1 | 0.5 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.1 | 0.5 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.5 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 1.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 1.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 0.3 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.1 | 1.1 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 0.4 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.1 | 3.8 | GO:0045638 | negative regulation of myeloid cell differentiation(GO:0045638) |
| 0.1 | 0.2 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 0.1 | 2.8 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.3 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.1 | 0.9 | GO:0042417 | dopamine metabolic process(GO:0042417) |
| 0.1 | 11.7 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.5 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 0.2 | GO:1903936 | response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936) |
| 0.0 | 0.6 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 2.8 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 10.8 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.3 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.0 | 0.4 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.0 | 0.1 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.0 | 0.4 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.0 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.8 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 2.6 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 0.0 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.0 | 0.0 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.0 | 4.8 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.4 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.1 | GO:1904845 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.0 | 0.5 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.0 | 0.1 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 1.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.1 | GO:1904245 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.0 | 0.2 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 1.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.3 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.0 | 0.2 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.0 | 0.0 | GO:0044851 | hair cycle phase(GO:0044851) |
| 0.0 | 0.1 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.0 | 0.1 | GO:0097210 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.0 | 0.1 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.0 | 0.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.9 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.2 | GO:0032225 | regulation of synaptic transmission, dopaminergic(GO:0032225) |
| 0.0 | 0.5 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.0 | 0.1 | GO:0090043 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.8 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.7 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.3 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 2.5 | GO:0060071 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) |
| 0.0 | 0.2 | GO:0051775 | response to redox state(GO:0051775) |
| 0.0 | 0.2 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.0 | 0.2 | GO:0071313 | cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415) |
| 0.0 | 0.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.2 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 0.0 | 0.5 | GO:0038084 | vascular endothelial growth factor signaling pathway(GO:0038084) |
| 0.0 | 1.6 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
| 0.0 | 1.2 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 2.8 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.0 | 0.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.0 | 3.5 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 3.0 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 0.5 | GO:0000737 | DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.3 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.3 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 0.3 | GO:0090312 | positive regulation of protein deacetylation(GO:0090312) |
| 0.0 | 0.1 | GO:0019477 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.0 | 0.1 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.0 | 0.1 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
| 0.0 | 0.8 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 0.1 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
| 0.0 | 0.3 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.0 | 0.2 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 0.4 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.4 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.2 | GO:0001556 | oocyte maturation(GO:0001556) |
| 0.0 | 0.6 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.0 | 0.5 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.0 | 0.1 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.0 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.0 | 0.1 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.4 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 0.2 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.7 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.1 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 0.2 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.0 | 0.3 | GO:0036065 | fucosylation(GO:0036065) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.7 | GO:0050805 | negative regulation of synaptic transmission(GO:0050805) |
| 0.0 | 0.6 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.1 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.4 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.0 | 0.5 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
| 0.0 | 0.4 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.0 | 0.1 | GO:0048840 | otolith development(GO:0048840) |
| 0.0 | 0.4 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.0 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 0.0 | 0.2 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 24.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 2.3 | 55.3 | GO:0071564 | npBAF complex(GO:0071564) |
| 2.0 | 9.8 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 1.5 | 25.5 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 1.2 | 27.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.9 | 2.6 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.9 | 3.4 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.6 | 2.8 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.5 | 1.5 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.5 | 2.8 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 9.9 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.3 | 1.9 | GO:0070695 | FHF complex(GO:0070695) |
| 0.2 | 12.1 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.2 | 5.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 2.9 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 7.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 0.8 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.2 | 0.5 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 0.2 | 0.9 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.2 | 1.1 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 2.0 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.4 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.1 | 4.2 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 1.0 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.7 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 58.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 3.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.9 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.1 | 17.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.3 | GO:0035841 | new growing cell tip(GO:0035841) |
| 0.1 | 1.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 4.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 1.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.8 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 5.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 0.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 0.9 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 0.6 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 28.4 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 1.3 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.4 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 2.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 2.3 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.5 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 3.9 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.1 | 1.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 0.3 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 1.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 4.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 0.2 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.1 | 1.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 30.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 1.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.2 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.1 | 0.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.1 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.7 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 3.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 11.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 4.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 1.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 1.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.4 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 3.6 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 0.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 2.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 4.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.4 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 0.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.5 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 1.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 6.2 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 3.9 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 9.2 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 13.5 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.4 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 2.0 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.2 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.1 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 0.4 | GO:0005921 | gap junction(GO:0005921) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 29.1 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 1.7 | 11.6 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 1.5 | 9.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.5 | 27.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 1.2 | 29.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 1.2 | 6.0 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.1 | 4.4 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.1 | 3.2 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 1.0 | 3.1 | GO:0070698 | type I activin receptor binding(GO:0070698) |
| 1.0 | 5.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.9 | 2.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.9 | 11.9 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.9 | 4.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.9 | 25.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.9 | 3.4 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.8 | 14.0 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.8 | 50.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.6 | 3.2 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.6 | 3.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.5 | 1.6 | GO:0090556 | apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.5 | 1.6 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 0.5 | 2.1 | GO:0046556 | alpha-L-arabinofuranosidase activity(GO:0046556) |
| 0.5 | 3.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 5.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.4 | 1.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.4 | 1.6 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.4 | 1.1 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.4 | 1.1 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.4 | 6.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.4 | 11.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.4 | 2.5 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.4 | 4.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.3 | 1.7 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.3 | 1.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.3 | 1.8 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.3 | 5.0 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.3 | 9.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.3 | 2.0 | GO:0005534 | galactose binding(GO:0005534) |
| 0.3 | 10.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.2 | 0.5 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.2 | 3.4 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 6.3 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.2 | 5.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 4.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.2 | 0.2 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.2 | 1.1 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.2 | 0.8 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.2 | 2.8 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.2 | 1.1 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.2 | 0.5 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.2 | 0.7 | GO:0016608 | growth hormone-releasing hormone activity(GO:0016608) |
| 0.2 | 2.8 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.5 | GO:0004951 | cholecystokinin receptor activity(GO:0004951) |
| 0.2 | 2.7 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.2 | 72.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.2 | 0.8 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.2 | 1.3 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.2 | 4.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 2.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 0.9 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.2 | 0.5 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.2 | 1.1 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.2 | 4.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.0 | GO:0047522 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.1 | 0.9 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.1 | 0.5 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.1 | 0.9 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.1 | 5.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 1.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.4 | GO:0061599 | molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.1 | 1.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 0.7 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 2.0 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.8 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.8 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.1 | 0.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 20.0 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 1.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 2.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 0.7 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 0.3 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.1 | 1.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 4.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.7 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.1 | 0.6 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 1.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.1 | 0.8 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.3 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 1.8 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 0.7 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.1 | 0.4 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 1.8 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 3.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.1 | 1.1 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 0.3 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.1 | 2.6 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 0.5 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.1 | 1.0 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.1 | 1.0 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.1 | 2.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.1 | 21.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.4 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 0.4 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 0.4 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.1 | 1.5 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.3 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 1.0 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.1 | 0.4 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.0 | 1.1 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.2 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.0 | 0.1 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.0 | 0.5 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 0.5 | GO:0047035 | alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.0 | 1.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 1.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 0.7 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 0.8 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.7 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 2.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.4 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.4 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.0 | 1.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 1.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 9.2 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 1.8 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.3 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.0 | 2.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 1.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 1.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 1.4 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.0 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 14.0 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.1 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.4 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.1 | GO:0016160 | amylase activity(GO:0016160) |
| 0.0 | 3.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.6 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 1.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.2 | GO:0050664 | superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) |
| 0.0 | 0.1 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.5 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 4.5 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.1 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.6 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.9 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
| 0.0 | 0.1 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.7 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 1.0 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.1 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 0.6 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.0 | 0.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.1 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 0.1 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 2.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.0 | 0.6 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 6.2 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.2 | GO:0030507 | spectrin binding(GO:0030507) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 70.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.6 | 55.2 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.5 | 24.4 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.5 | 24.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.3 | 33.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.2 | 5.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.2 | 9.4 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.2 | 11.6 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 5.5 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 14.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 3.3 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 4.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 5.6 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 5.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 8.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 2.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 6.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.6 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 1.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 3.6 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 5.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 1.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 3.6 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 15.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.2 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 0.9 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 1.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 3.2 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 4.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.5 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 3.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.1 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.4 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.7 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.1 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 0.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.0 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 53.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.8 | 25.7 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.7 | 27.5 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.7 | 11.9 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.5 | 11.4 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.3 | 4.4 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.2 | 14.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.2 | 5.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 4.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 3.8 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 6.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 3.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 4.1 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 5.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 3.2 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.1 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 0.5 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 9.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 2.0 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.1 | 1.8 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 2.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.2 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 1.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 1.2 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 8.1 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.1 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 4.4 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.1 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.0 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.6 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 0.6 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.4 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 1.1 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 1.6 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.0 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.7 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 1.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.7 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.2 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.2 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 1.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.7 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 2.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.1 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.1 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.8 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.7 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.1 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.2 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.0 | 0.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.3 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.7 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |