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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXB8

Z-value: 0.93

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Transcription factors associated with HOXB8

Gene Symbol Gene ID Gene Info
HOXB8
ENSG00000120068.5 homeobox B8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB8hg19_v2_chr17_-_46692287_466923170.116.2e-01Click!

Activity profile of HOXB8 motif

Sorted Z-values of HOXB8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_123542224 2.09 ENST00000264497.3
IL21
interleukin 21
chr12_+_113354341 2.09 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_72649763 1.61 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr10_-_90712520 1.33 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr4_+_36283213 1.27 ENST00000357504.3
DTHD1
death domain containing 1
chr8_+_31497271 1.18 ENST00000520407.1
NRG1
neuregulin 1
chr4_-_76944621 1.14 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr5_+_156696362 1.13 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_+_148545586 1.07 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr16_-_28634874 1.03 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_-_3595181 1.00 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr13_-_33760216 0.98 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_115670792 0.91 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr7_-_115670804 0.91 ENST00000320239.7
TFEC
transcription factor EC
chr3_+_173116225 0.91 ENST00000457714.1
NLGN1
neuroligin 1
chr11_-_5345582 0.90 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr5_-_135290705 0.88 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr10_+_13141585 0.86 ENST00000378764.2
OPTN
optineurin
chr9_+_72658490 0.84 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr19_+_55315087 0.83 ENST00000345540.5
ENST00000357494.4
ENST00000396293.1
ENST00000346587.4
ENST00000396289.5
KIR2DL4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr7_-_138363824 0.82 ENST00000419765.3
SVOPL
SVOP-like
chr8_+_104892639 0.81 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr11_+_5710919 0.80 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr10_-_106240032 0.77 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr1_+_244515930 0.77 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr6_-_119031228 0.77 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr11_-_102496063 0.77 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr16_-_46655538 0.76 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr10_+_13142225 0.75 ENST00000378747.3
OPTN
optineurin
chr11_+_55029628 0.71 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr9_+_33629119 0.70 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr2_-_202562716 0.70 ENST00000428900.2
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr9_-_85882145 0.69 ENST00000328788.1
FRMD3
FERM domain containing 3
chr11_-_27723158 0.69 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr1_+_87012753 0.69 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr7_-_27142290 0.68 ENST00000222718.5
HOXA2
homeobox A2
chr7_+_75024903 0.68 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr1_+_214776516 0.68 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr12_-_7596735 0.68 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr4_+_74347400 0.68 ENST00000226355.3
AFM
afamin
chr22_-_22337146 0.67 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr10_+_13142075 0.65 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr22_-_22863466 0.62 ENST00000406426.1
ENST00000360412.2
ZNF280B
zinc finger protein 280B
chr3_-_145878954 0.62 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr5_-_41213607 0.62 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr12_+_113416191 0.62 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr4_-_70080449 0.62 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chrX_-_19988382 0.62 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr4_+_123653807 0.62 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr3_-_79816965 0.61 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr3_-_191000172 0.61 ENST00000427544.2
UTS2B
urotensin 2B
chr5_-_58295712 0.60 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_70146217 0.59 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr1_+_24645807 0.59 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_12908578 0.59 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr15_-_80263506 0.58 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chrX_-_110655306 0.57 ENST00000371993.2
DCX
doublecortin
chr1_-_205091115 0.57 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr10_+_13141441 0.56 ENST00000263036.5
OPTN
optineurin
chr10_-_79789291 0.56 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr7_-_92747269 0.56 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr1_+_24645865 0.55 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_+_129083772 0.55 ENST00000564719.1
KIAA1024L
KIAA1024-like
chr22_-_22337204 0.55 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr7_-_139763521 0.55 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr6_-_44281043 0.54 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr3_-_58613323 0.53 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chrX_+_30261847 0.52 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr21_-_15918618 0.52 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_104615595 0.52 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chrX_-_77225135 0.51 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr10_+_57358750 0.51 ENST00000512524.2
MTRNR2L5
MT-RNR2-like 5
chr1_-_158656488 0.50 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_55177416 0.50 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr12_+_20968608 0.50 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr18_+_21693306 0.50 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr11_-_111649015 0.49 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr5_-_41261540 0.49 ENST00000263413.3
C6
complement component 6
chr14_+_88851874 0.49 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr10_+_115674530 0.49 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr3_-_43147549 0.48 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr18_-_19994830 0.48 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr6_-_52705641 0.47 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr12_+_9980069 0.47 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr19_+_55315059 0.47 ENST00000359085.4
KIR2DL4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr6_+_160327974 0.47 ENST00000252660.4
MAS1
MAS1 oncogene
chr22_-_22337154 0.46 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr12_-_118628350 0.46 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr14_+_74058410 0.46 ENST00000326303.4
ACOT4
acyl-CoA thioesterase 4
chrX_+_2976652 0.46 ENST00000537104.1
ARSF
arylsulfatase F
chr5_+_121465207 0.46 ENST00000296600.4
ZNF474
zinc finger protein 474
chr7_-_32529973 0.46 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_22520762 0.46 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr11_+_18417813 0.45 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr10_-_120925054 0.45 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4
sideroflexin 4
chr9_+_128509624 0.45 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr11_-_7818520 0.44 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr12_+_32655110 0.44 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr10_+_69865866 0.44 ENST00000354393.2
MYPN
myopalladin
chr12_+_14956506 0.44 ENST00000330828.2
C12orf60
chromosome 12 open reading frame 60
chr2_-_190044480 0.43 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr16_-_30122717 0.43 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr11_+_134201768 0.43 ENST00000535456.2
ENST00000339772.7
GLB1L2
galactosidase, beta 1-like 2
chr19_-_10697895 0.43 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr5_-_59481406 0.43 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_-_53737722 0.43 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr11_+_7618413 0.43 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_-_79233314 0.43 ENST00000282003.6
RNF219
ring finger protein 219
chr3_-_107777208 0.42 ENST00000398258.3
CD47
CD47 molecule
chr6_+_34204642 0.42 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr3_-_112564797 0.42 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr15_-_28957469 0.42 ENST00000563027.1
ENST00000340249.3
GOLGA8M
golgin A8 family, member M
chr2_+_90108504 0.42 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr6_+_26365443 0.41 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr16_-_21663919 0.41 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_-_112106578 0.41 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr12_+_8309630 0.41 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr8_+_95565947 0.41 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr17_-_69198295 0.41 ENST00000569074.1
CASC17
cancer susceptibility candidate 17 (non-protein coding)
chr9_-_21351377 0.41 ENST00000380210.1
IFNA6
interferon, alpha 6
chr7_-_71868354 0.41 ENST00000412588.1
CALN1
calneuron 1
chr11_-_28129656 0.40 ENST00000263181.6
KIF18A
kinesin family member 18A
chr7_+_77325738 0.40 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr20_-_54967187 0.40 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr1_+_24646002 0.40 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr10_-_47173994 0.40 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr9_+_125132803 0.40 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr19_-_37663332 0.40 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr4_-_70518941 0.40 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr8_-_29208183 0.40 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr19_+_13135386 0.40 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_35417798 0.40 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
ZNF30
zinc finger protein 30
chr3_-_12587055 0.40 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr1_-_247921982 0.40 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chrX_-_154033661 0.39 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr21_-_30365136 0.39 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr4_+_156824840 0.39 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr7_-_122635754 0.39 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr12_+_21679220 0.39 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr8_+_7353368 0.39 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr9_+_111624577 0.39 ENST00000333999.3
ACTL7A
actin-like 7A
chr3_+_148508845 0.39 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr7_+_142498725 0.39 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr10_-_77161650 0.38 ENST00000372524.4
ZNF503
zinc finger protein 503
chr16_-_4817129 0.38 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr18_-_10701979 0.38 ENST00000538948.1
ENST00000285141.4
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr10_-_14996321 0.38 ENST00000378289.4
DCLRE1C
DNA cross-link repair 1C
chr5_-_78809950 0.37 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr5_+_175740083 0.37 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr1_-_67142710 0.37 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr8_-_72756667 0.37 ENST00000325509.4
MSC
musculin
chr11_+_96123158 0.37 ENST00000332349.4
ENST00000458427.1
JRKL
jerky homolog-like (mouse)
chr12_-_122985067 0.36 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr5_+_131892603 0.36 ENST00000378823.3
ENST00000265335.6
RAD50
RAD50 homolog (S. cerevisiae)
chr8_-_134072593 0.36 ENST00000427060.2
SLA
Src-like-adaptor
chr5_-_38557561 0.36 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr14_+_22977587 0.36 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr11_+_67219867 0.36 ENST00000438189.2
CABP4
calcium binding protein 4
chr5_+_159848854 0.36 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr1_-_112106556 0.35 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr7_-_99149715 0.35 ENST00000449309.1
FAM200A
family with sequence similarity 200, member A
chr14_-_101295407 0.35 ENST00000596284.1
AL117190.2
AL117190.2
chr10_+_71561630 0.35 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr1_+_84873913 0.35 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr22_+_23077065 0.35 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr18_+_61554932 0.35 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr8_-_125486755 0.35 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr19_+_782755 0.35 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr6_+_72926145 0.35 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_5410607 0.35 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr15_-_72523454 0.34 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
PKM
pyruvate kinase, muscle
chr10_+_62538248 0.34 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr10_+_94352956 0.34 ENST00000260731.3
KIF11
kinesin family member 11
chr15_+_69706643 0.34 ENST00000352331.4
ENST00000260363.4
KIF23
kinesin family member 23
chr1_-_247697141 0.34 ENST00000366487.3
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr6_-_133084580 0.33 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr16_-_740354 0.33 ENST00000293883.4
WDR24
WD repeat domain 24
chr6_-_36842784 0.33 ENST00000373699.5
PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr19_-_52598958 0.33 ENST00000594440.1
ENST00000426391.2
ENST00000389534.4
ZNF841
zinc finger protein 841
chrX_+_52926322 0.33 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr19_-_44388116 0.33 ENST00000587539.1
ZNF404
zinc finger protein 404
chr3_+_120461484 0.33 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr4_-_177116772 0.32 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr12_-_371994 0.32 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chrX_-_106243451 0.32 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr16_-_740419 0.32 ENST00000248142.6
WDR24
WD repeat domain 24
chr5_-_10761206 0.32 ENST00000432074.2
ENST00000230895.6
DAP
death-associated protein
chr19_+_35417844 0.32 ENST00000601957.1
ZNF30
zinc finger protein 30
chr20_-_1309809 0.32 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr2_+_105050794 0.32 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr15_-_89089860 0.32 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1
de-etiolated homolog 1 (Arabidopsis)
chr11_-_5323226 0.32 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr1_-_28241226 0.32 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr9_+_125133315 0.32 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_+_47894572 0.32 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr7_-_45151272 0.31 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
TBRG4
transforming growth factor beta regulator 4
chrX_+_134124968 0.31 ENST00000330288.4
SMIM10
small integral membrane protein 10
chrX_+_56590002 0.31 ENST00000338222.5
UBQLN2
ubiquilin 2
chr14_-_74417096 0.31 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr5_+_54398463 0.31 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 0.9 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 1.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.3 0.8 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 0.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 0.7 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.3 GO:0090131 mesenchyme migration(GO:0090131)
0.2 0.6 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 0.6 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.2 GO:0015747 urate transport(GO:0015747)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 1.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 1.0 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 2.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.4 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1 0.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.8 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.1 0.4 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.3 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 1.7 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.1 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.3 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 1.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 1.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.9 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.2 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 1.0 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018) regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.0 GO:0071231 cellular response to folic acid(GO:0071231)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.5 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.2 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0043605 allantoin metabolic process(GO:0000255) cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.5 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 1.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 2.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0060437 lung growth(GO:0060437) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:1900368 pre-miRNA export from nucleus(GO:0035281) regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0061046 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) mesenchymal-epithelial cell signaling(GO:0060638) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 1.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.0 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0006568 tryptophan metabolic process(GO:0006568)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.4 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0045046 peroxisome fission(GO:0016559) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0002839 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.0 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.3 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.4 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0005499 vitamin D binding(GO:0005499)
0.3 2.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 2.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.7 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 2.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions