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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXC11

Z-value: 0.58

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 homeobox C11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC11hg19_v2_chr12_+_54366894_543669220.222.8e-01Click!

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32812568 1.58 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr7_-_47579188 0.91 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3
tensin 3
chr3_-_79816965 0.90 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_127898312 0.84 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr7_+_35756092 0.82 ENST00000458087.3
AC018647.3
AC018647.3
chr7_+_35756186 0.81 ENST00000430518.1
AC018647.3
AC018647.3
chr15_+_67418047 0.73 ENST00000540846.2
SMAD3
SMAD family member 3
chr20_+_52105495 0.68 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_+_228678550 0.65 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr17_+_7461613 0.65 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_-_81399411 0.58 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_-_37216055 0.57 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr12_-_52779433 0.57 ENST00000257951.3
KRT84
keratin 84
chr2_-_136678123 0.56 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr4_-_174451370 0.55 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr17_-_39646116 0.54 ENST00000328119.6
KRT36
keratin 36
chr1_-_12677714 0.53 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr19_+_46367518 0.53 ENST00000302177.2
FOXA3
forkhead box A3
chr2_-_190044480 0.53 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr16_+_57653989 0.51 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr10_-_24770632 0.51 ENST00000596413.1
AL353583.1
AL353583.1
chr16_+_57653854 0.50 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr5_-_36301984 0.49 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr1_-_237167718 0.46 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr19_-_10420459 0.45 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr4_+_95972822 0.44 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr22_+_41697520 0.44 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr2_-_145278475 0.42 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_209878182 0.41 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_+_108210012 0.37 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_-_77924627 0.36 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr8_+_38831683 0.35 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr2_+_166428839 0.34 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_-_133814455 0.34 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr8_+_104831472 0.33 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr6_+_108487245 0.33 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr1_+_209859510 0.33 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr3_-_57326704 0.33 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr1_-_204135450 0.32 ENST00000272190.8
ENST00000367195.2
REN
renin
chr1_-_9129895 0.32 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_-_106240032 0.32 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr4_+_146539415 0.30 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr4_+_169013666 0.30 ENST00000359299.3
ANXA10
annexin A10
chr5_-_76935513 0.29 ENST00000306422.3
OTP
orthopedia homeobox
chr12_+_70219052 0.29 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr3_-_71294304 0.29 ENST00000498215.1
FOXP1
forkhead box P1
chr3_+_173116225 0.28 ENST00000457714.1
NLGN1
neuroligin 1
chr6_+_26156551 0.27 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr7_-_20826504 0.27 ENST00000418710.2
ENST00000361443.4
SP8
Sp8 transcription factor
chr17_-_39684550 0.26 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr7_-_27169801 0.26 ENST00000511914.1
HOXA4
homeobox A4
chr10_-_115614127 0.26 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr22_+_39916558 0.26 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr12_+_130646999 0.26 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr14_+_97925151 0.25 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr1_+_75600567 0.25 ENST00000356261.3
LHX8
LIM homeobox 8
chr11_-_132813566 0.24 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr11_-_5537920 0.22 ENST00000380184.1
UBQLNL
ubiquilin-like
chr11_+_34664014 0.22 ENST00000527935.1
EHF
ets homologous factor
chr2_-_68052694 0.22 ENST00000457448.1
AC010987.6
AC010987.6
chr19_+_1440838 0.22 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr1_+_167298281 0.21 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr6_+_132873832 0.21 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr11_-_118305921 0.20 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr20_+_58713514 0.20 ENST00000432910.1
RP5-1043L13.1
RP5-1043L13.1
chr6_-_64029879 0.20 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr1_-_152131703 0.20 ENST00000316073.3
RPTN
repetin
chr9_+_44868935 0.20 ENST00000448436.2
RP11-160N1.10
RP11-160N1.10
chr6_+_46761118 0.19 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr8_+_104831554 0.19 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_114710516 0.19 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_-_57272366 0.18 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr7_-_108209897 0.18 ENST00000313516.5
THAP5
THAP domain containing 5
chr12_+_25205666 0.18 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr14_-_101295407 0.17 ENST00000596284.1
AL117190.2
AL117190.2
chr12_-_111358372 0.17 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr8_-_18666360 0.17 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr20_+_58179582 0.17 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr3_+_63428982 0.17 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr4_-_107957454 0.16 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr10_+_26505179 0.16 ENST00000376261.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr7_-_81399329 0.16 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_-_16705069 0.16 ENST00000471301.2
BNC2
basonuclin 2
chr3_-_45838011 0.15 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr5_+_145718587 0.15 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr5_-_115872142 0.15 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_-_45837959 0.14 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr6_-_137815524 0.14 ENST00000367734.2
OLIG3
oligodendrocyte transcription factor 3
chr5_+_176731572 0.14 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr14_-_57277178 0.14 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr8_+_134203303 0.14 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr7_+_114055052 0.14 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr10_-_96829246 0.14 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr16_-_67978016 0.14 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr13_-_46679185 0.13 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr17_-_79876010 0.13 ENST00000328666.6
SIRT7
sirtuin 7
chrX_+_65382433 0.13 ENST00000374727.3
HEPH
hephaestin
chr14_-_25479811 0.13 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr13_-_46679144 0.13 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr12_-_47219733 0.13 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr5_+_67586465 0.12 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_109799793 0.12 ENST00000297459.3
TMEM74
transmembrane protein 74
chrX_+_65382381 0.12 ENST00000519389.1
HEPH
hephaestin
chrX_+_65384182 0.12 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr2_-_166930131 0.12 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr17_+_58018269 0.12 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr20_+_42984330 0.11 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chrX_+_65384052 0.11 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr15_+_49715293 0.11 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr19_+_19626531 0.11 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr14_+_73706308 0.10 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr22_-_30642782 0.10 ENST00000249075.3
LIF
leukemia inhibitory factor
chr9_-_124990680 0.09 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chr2_+_68872954 0.09 ENST00000394342.2
PROKR1
prokineticin receptor 1
chrX_-_100604184 0.09 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr16_+_67906919 0.09 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr7_-_81399355 0.09 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr19_-_19626838 0.08 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr8_-_114449112 0.08 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr1_+_23345943 0.08 ENST00000400181.4
ENST00000542151.1
KDM1A
lysine (K)-specific demethylase 1A
chr7_-_81399438 0.08 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr21_+_35736302 0.08 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr12_-_18243119 0.08 ENST00000538724.1
ENST00000229002.2
RERGL
RERG/RAS-like
chr5_-_34043310 0.08 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr1_+_23345930 0.08 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chrX_+_14547632 0.07 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr16_-_2314222 0.07 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr17_-_41739283 0.07 ENST00000393661.2
ENST00000318579.4
MEOX1
mesenchyme homeobox 1
chr15_-_68497657 0.06 ENST00000448060.2
ENST00000467889.1
CALML4
calmodulin-like 4
chr9_+_95736758 0.06 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr19_+_35634146 0.06 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr1_-_9129735 0.06 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_-_20053741 0.06 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr8_-_59412717 0.06 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr19_-_36233332 0.06 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr15_+_36887069 0.06 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr2_+_149402553 0.06 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr7_-_75401513 0.06 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr1_-_9129631 0.05 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_+_4402659 0.05 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr12_+_52203789 0.05 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr8_-_21669826 0.05 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chr11_+_34663913 0.05 ENST00000532302.1
EHF
ets homologous factor
chr6_-_91296602 0.05 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr18_+_63417864 0.05 ENST00000536984.2
CDH7
cadherin 7, type 2
chr2_+_211421262 0.05 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr8_+_134203273 0.05 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr12_-_24102576 0.05 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5
SRY (sex determining region Y)-box 5
chr1_+_183774240 0.04 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr6_-_91296737 0.04 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr5_+_148521381 0.04 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr13_-_103719196 0.04 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr14_-_60952739 0.04 ENST00000555476.1
ENST00000321731.3
C14orf39
chromosome 14 open reading frame 39
chr19_+_36036477 0.04 ENST00000222284.5
ENST00000392204.2
TMEM147
transmembrane protein 147
chr15_-_54025300 0.04 ENST00000559418.1
WDR72
WD repeat domain 72
chr8_-_95220775 0.04 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr6_-_31745085 0.03 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr5_-_169626104 0.03 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr17_-_46806540 0.03 ENST00000290295.7
HOXB13
homeobox B13
chr16_-_21663919 0.03 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr7_+_134464376 0.03 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr2_-_207023918 0.03 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chrX_-_105282712 0.03 ENST00000372563.1
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr22_+_41956767 0.03 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr12_+_25205568 0.03 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr14_-_57277163 0.03 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr6_-_41703952 0.03 ENST00000358871.2
ENST00000403298.4
TFEB
transcription factor EB
chr19_+_36036583 0.03 ENST00000392205.1
TMEM147
transmembrane protein 147
chr3_+_89156799 0.03 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr1_-_242162375 0.03 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr2_+_128293323 0.02 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr8_-_57123815 0.02 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr7_-_151217001 0.02 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr12_-_52828147 0.02 ENST00000252245.5
KRT75
keratin 75
chr6_-_31745037 0.02 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr16_-_3350614 0.02 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr19_-_39924349 0.02 ENST00000602153.1
RPS16
ribosomal protein S16
chr4_-_87028478 0.02 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr6_+_88054530 0.01 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr2_+_158114051 0.01 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_-_107682702 0.01 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr1_+_46152886 0.01 ENST00000372025.4
TMEM69
transmembrane protein 69
chr8_+_76452097 0.01 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_200379180 0.01 ENST00000294740.3
ZNF281
zinc finger protein 281
chr7_-_122840015 0.00 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr1_-_7913089 0.00 ENST00000361696.5
UTS2
urotensin 2
chr7_-_41742697 0.00 ENST00000242208.4
INHBA
inhibin, beta A
chr16_+_14805546 0.00 ENST00000552140.1
NPIPA3
nuclear pore complex interacting protein family, member A3
chr20_+_4702548 0.00 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr13_-_81801115 0.00 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 0.6 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.6 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.5 GO:0003219 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.1 0.3 GO:0099545 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.6 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:1902159 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.9 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation