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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXC12_HOXD12

Z-value: 0.96

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC12hg19_v2_chr12_+_54348618_54348693-0.232.7e-01Click!
HOXD12hg19_v2_chr2_+_176964458_176964540-0.154.8e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_113354341 4.14 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr21_-_46012386 2.96 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr7_-_41742697 2.55 ENST00000242208.4
INHBA
inhibin, beta A
chr15_-_99789736 1.84 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr13_+_53030107 1.74 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr7_-_27183263 1.52 ENST00000222726.3
HOXA5
homeobox A5
chr3_-_112127981 1.39 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr11_+_7618413 1.35 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_-_27219849 1.33 ENST00000396344.4
HOXA10
homeobox A10
chr1_+_158975744 1.22 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr19_-_48752812 1.18 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr11_-_107328527 1.17 ENST00000282251.5
ENST00000433523.1
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr19_-_48753104 1.15 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr7_-_27169801 1.13 ENST00000511914.1
HOXA4
homeobox A4
chr19_-_23941680 1.13 ENST00000402377.3
ZNF681
zinc finger protein 681
chr18_+_3466248 1.11 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr1_-_47407097 1.09 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr7_+_138145145 1.07 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr3_+_132036243 1.00 ENST00000475741.1
ENST00000351273.7
ACPP
acid phosphatase, prostate
chr12_-_30887948 0.99 ENST00000433722.2
CAPRIN2
caprin family member 2
chr13_+_53029564 0.98 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr10_-_52383644 0.97 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr1_+_158900568 0.88 ENST00000458222.1
PYHIN1
pyrin and HIN domain family, member 1
chrY_+_2709527 0.84 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr7_+_138145076 0.84 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr10_-_90712520 0.84 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr21_-_31859755 0.84 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr1_+_63989004 0.82 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr11_+_22696314 0.81 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr10_-_113943447 0.80 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr4_-_123843597 0.80 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr19_-_44905741 0.80 ENST00000591679.1
ENST00000544719.2
ENST00000330997.4
ENST00000585868.1
ENST00000588212.1
ZNF285
CTC-512J12.6
zinc finger protein 285
Uncharacterized protein
chr12_+_6603253 0.79 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr7_+_90339169 0.79 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr11_-_102668879 0.78 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr3_-_18466026 0.76 ENST00000417717.2
SATB1
SATB homeobox 1
chr4_-_148605265 0.76 ENST00000541232.1
ENST00000322396.6
PRMT10
protein arginine methyltransferase 10 (putative)
chr1_-_15735925 0.76 ENST00000427824.1
RP3-467K16.4
RP3-467K16.4
chrY_+_26997726 0.75 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr2_+_74056066 0.73 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP
STAM binding protein
chr16_-_28303360 0.73 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr8_-_93029865 0.73 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_159656437 0.72 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr17_+_56769924 0.72 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr9_-_124976154 0.71 ENST00000482062.1
LHX6
LIM homeobox 6
chr9_-_124976185 0.71 ENST00000464484.2
LHX6
LIM homeobox 6
chr3_+_32737027 0.68 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr5_+_169010638 0.67 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr2_-_170430366 0.67 ENST00000453153.2
ENST00000445210.1
FASTKD1
FAST kinase domains 1
chr3_+_143690640 0.67 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr9_+_137979506 0.66 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr19_-_48759119 0.63 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
CARD8
caspase recruitment domain family, member 8
chr10_-_70287231 0.62 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr13_+_50570019 0.60 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr8_+_107738240 0.60 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr1_+_219347203 0.59 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr19_+_42212501 0.58 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr13_-_79233314 0.58 ENST00000282003.6
RNF219
ring finger protein 219
chr21_-_15918618 0.57 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr8_+_118147498 0.57 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr2_+_190541153 0.56 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr12_-_10007448 0.56 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr1_+_202431859 0.56 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_+_67624430 0.55 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr6_+_71122974 0.55 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr2_-_177502254 0.54 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr13_+_34392200 0.53 ENST00000434425.1
RFC3
replication factor C (activator 1) 3, 38kDa
chr11_+_111896090 0.52 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr2_-_211179883 0.51 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr6_-_166796461 0.49 ENST00000360961.6
ENST00000341756.6
MPC1
mitochondrial pyruvate carrier 1
chr8_-_13134045 0.49 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr13_-_46543805 0.48 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr1_-_101491319 0.48 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr12_-_31743901 0.47 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr13_+_53602894 0.46 ENST00000219022.2
OLFM4
olfactomedin 4
chr19_-_48753028 0.46 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr8_-_92053212 0.46 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr6_-_51952418 0.45 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr19_+_21264980 0.44 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr2_+_101869262 0.44 ENST00000289382.3
CNOT11
CCR4-NOT transcription complex, subunit 11
chr2_+_61372226 0.44 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr19_-_48753064 0.43 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
CARD8
caspase recruitment domain family, member 8
chr20_+_36946029 0.43 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr9_-_130533615 0.43 ENST00000373277.4
SH2D3C
SH2 domain containing 3C
chr2_+_37571845 0.43 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_+_37571717 0.42 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_-_201753717 0.41 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr4_+_39460620 0.41 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr12_-_95945246 0.41 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr14_-_22005343 0.41 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr7_+_64838786 0.41 ENST00000450302.2
ZNF92
zinc finger protein 92
chr19_+_21106081 0.40 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chrX_-_133792480 0.40 ENST00000359237.4
PLAC1
placenta-specific 1
chr3_+_148508845 0.40 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr1_+_171750776 0.40 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr12_-_11287243 0.39 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr19_+_37342547 0.38 ENST00000331800.4
ENST00000586646.1
ZNF345
zinc finger protein 345
chr11_+_101785727 0.38 ENST00000263468.8
KIAA1377
KIAA1377
chr2_-_201753980 0.38 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr7_+_149535455 0.37 ENST00000223210.4
ENST00000460379.1
ZNF862
zinc finger protein 862
chr3_-_56502375 0.37 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr13_-_47471155 0.37 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr20_+_36932521 0.36 ENST00000262865.4
BPI
bactericidal/permeability-increasing protein
chr3_+_16306837 0.36 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chrY_+_2709906 0.36 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr9_+_2029019 0.36 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_1071796 0.36 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr12_-_88535747 0.36 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr7_+_64838712 0.35 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr2_-_201753859 0.35 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr2_+_74056147 0.35 ENST00000394070.2
ENST00000536064.1
STAMBP
STAM binding protein
chr14_-_39901618 0.34 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr14_+_90422239 0.34 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr1_+_219347186 0.34 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr10_-_74856608 0.33 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr22_-_36925186 0.33 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr22_-_36924944 0.32 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr19_-_23869970 0.32 ENST00000601010.1
ZNF675
zinc finger protein 675
chr2_+_201754050 0.32 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_-_11986442 0.32 ENST00000376572.3
ENST00000376576.3
KIAA2013
KIAA2013
chr19_+_21579958 0.32 ENST00000339914.6
ENST00000599461.1
ZNF493
zinc finger protein 493
chr14_+_57046530 0.32 ENST00000536419.1
ENST00000538838.1
TMEM260
transmembrane protein 260
chr9_-_98269481 0.32 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr3_+_137906109 0.31 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr19_+_21579908 0.31 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr17_-_36904437 0.31 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr10_-_99052382 0.31 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr2_+_138721850 0.30 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr9_+_115513003 0.30 ENST00000374232.3
SNX30
sorting nexin family member 30
chr8_+_17013515 0.30 ENST00000262096.8
ZDHHC2
zinc finger, DHHC-type containing 2
chr10_-_70287172 0.30 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr5_+_135468516 0.30 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chrX_-_100548045 0.29 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr16_+_67906919 0.29 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr7_+_152456904 0.29 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr2_-_100721923 0.29 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr17_-_29624343 0.29 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr12_+_120105558 0.29 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr14_-_68000442 0.28 ENST00000554278.1
TMEM229B
transmembrane protein 229B
chr7_+_57509877 0.28 ENST00000420713.1
ZNF716
zinc finger protein 716
chr7_-_112758665 0.28 ENST00000397764.3
LINC00998
long intergenic non-protein coding RNA 998
chr4_+_6202448 0.28 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr7_+_90012986 0.28 ENST00000416322.1
CLDN12
claudin 12
chr21_+_46359907 0.28 ENST00000291634.6
ENST00000397826.3
ENST00000458015.1
FAM207A
family with sequence similarity 207, member A
chr7_-_121944491 0.27 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr5_+_140254884 0.27 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr11_+_111896320 0.27 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr7_-_99149715 0.27 ENST00000449309.1
FAM200A
family with sequence similarity 200, member A
chr4_-_16085340 0.26 ENST00000508167.1
PROM1
prominin 1
chr5_+_140535577 0.26 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr19_+_21265028 0.26 ENST00000291770.7
ZNF714
zinc finger protein 714
chr2_+_201754135 0.25 ENST00000409357.1
ENST00000409129.2
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_+_117297007 0.25 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr17_+_18759612 0.25 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr14_+_21387508 0.25 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr17_-_7232585 0.25 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr20_-_17539456 0.25 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr14_+_57046500 0.25 ENST00000261556.6
TMEM260
transmembrane protein 260
chr17_-_73127778 0.25 ENST00000578407.1
NT5C
5', 3'-nucleotidase, cytosolic
chr1_-_23504176 0.25 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr4_-_682960 0.25 ENST00000512249.1
ENST00000515118.1
ENST00000347950.5
MFSD7
major facilitator superfamily domain containing 7
chr19_-_38085633 0.24 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr14_+_55494323 0.24 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr1_-_23886285 0.24 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr5_+_140514782 0.24 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr4_-_16085314 0.24 ENST00000510224.1
PROM1
prominin 1
chr12_-_6602955 0.24 ENST00000543703.1
MRPL51
mitochondrial ribosomal protein L51
chr1_-_161015752 0.24 ENST00000435396.1
ENST00000368021.3
USF1
upstream transcription factor 1
chr3_+_179322481 0.24 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr3_-_165555200 0.24 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr17_-_73127826 0.23 ENST00000582170.1
ENST00000245552.2
NT5C
5', 3'-nucleotidase, cytosolic
chr18_-_19994830 0.23 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr4_-_153601136 0.23 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr2_-_27435125 0.23 ENST00000414408.1
ENST00000310574.3
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr6_-_116601044 0.23 ENST00000368608.3
TSPYL1
TSPY-like 1
chr1_+_151584544 0.23 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr4_-_95264008 0.23 ENST00000295256.5
HPGDS
hematopoietic prostaglandin D synthase
chr10_+_6625733 0.23 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr8_+_16884740 0.23 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr1_+_149230680 0.23 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr19_-_58326267 0.23 ENST00000391701.1
ZNF552
zinc finger protein 552
chr11_+_35160709 0.23 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44
CD44 molecule (Indian blood group)
chr7_+_76090993 0.22 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr11_+_36616044 0.22 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr19_-_23869999 0.22 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr12_-_76879852 0.22 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr7_-_130080977 0.22 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr14_+_21387491 0.22 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr14_-_50319758 0.21 ENST00000298310.5
NEMF
nuclear export mediator factor
chr17_-_71228357 0.21 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A
family with sequence similarity 104, member A
chr4_+_110354928 0.21 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24B
SEC24 family member B
chrX_+_118425471 0.21 ENST00000428222.1
RP5-1139I1.1
RP5-1139I1.1
chr22_+_23134974 0.21 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr5_+_140227048 0.21 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr13_+_78315466 0.21 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr14_-_50319482 0.20 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr5_+_140213815 0.20 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr18_-_5544241 0.20 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr4_-_83765613 0.20 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr20_-_48782639 0.20 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 1.5 GO:0060435 bronchiole development(GO:0060435)
0.3 1.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 0.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3 1.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 3.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2 0.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 0.8 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 1.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 2.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.7 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.2 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.2 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 5.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.9 GO:0010510 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 1.3 GO:0060065 uterus development(GO:0060065)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.8 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 1.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0071051 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.7 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.6 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.7 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 3.0 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 3.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 0.8 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 3.9 GO:0032089 NACHT domain binding(GO:0032089)
0.4 1.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.4 4.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 0.8 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 0.6 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.9 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.7 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.6 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0019784 SUMO-specific protease activity(GO:0016929) NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 4.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease