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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXC13

Z-value: 0.54

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
HOXC13
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.145.2e-01Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112127981 1.85 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr2_+_161993465 0.73 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr9_-_74675521 0.69 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr11_+_118175132 0.67 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr2_+_162016827 0.65 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr1_-_150208320 0.60 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr21_-_27423339 0.58 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr11_+_30252549 0.56 ENST00000254122.3
ENST00000417547.1
FSHB
follicle stimulating hormone, beta polypeptide
chr2_-_177502254 0.54 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr21_-_46012386 0.53 ENST00000400368.1
KRTAP10-6
keratin associated protein 10-6
chr12_+_45609862 0.44 ENST00000423947.3
ENST00000435642.1
ANO6
anoctamin 6
chr2_+_161993412 0.43 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr12_+_45609797 0.43 ENST00000425752.2
ANO6
anoctamin 6
chr6_-_11807277 0.42 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr2_+_162016804 0.39 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr12_-_47473425 0.38 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr16_-_68033356 0.36 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
DPEP2
dipeptidase 2
chr2_+_162016916 0.33 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr17_-_3496171 0.33 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr16_-_46865286 0.31 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr3_-_155461515 0.29 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr17_+_56769924 0.27 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr13_+_34392185 0.26 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr14_+_96722539 0.26 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr1_+_109656719 0.25 ENST00000457623.2
ENST00000529753.1
KIAA1324
KIAA1324
chr12_+_96883347 0.25 ENST00000524981.4
ENST00000298953.3
C12orf55
chromosome 12 open reading frame 55
chr2_+_241499719 0.25 ENST00000405954.1
DUSP28
dual specificity phosphatase 28
chr1_-_150208291 0.24 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_-_58571445 0.24 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr7_+_134551583 0.24 ENST00000435928.1
CALD1
caldesmon 1
chr5_+_134181625 0.22 ENST00000394976.3
C5orf24
chromosome 5 open reading frame 24
chr1_-_166845515 0.22 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr10_+_94352956 0.22 ENST00000260731.3
KIF11
kinesin family member 11
chr1_+_109656532 0.21 ENST00000531664.1
ENST00000534476.1
KIAA1324
KIAA1324
chrX_-_30993201 0.21 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_174128639 0.21 ENST00000251507.4
RABGAP1L
RAB GTPase activating protein 1-like
chr4_+_54243917 0.20 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr4_-_128887069 0.20 ENST00000541133.1
ENST00000296468.3
ENST00000513559.1
MFSD8
major facilitator superfamily domain containing 8
chr1_-_150208363 0.20 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_+_141178440 0.20 ENST00000394205.3
SCOC
short coiled-coil protein
chr1_+_84630645 0.19 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_109656579 0.19 ENST00000526264.1
ENST00000369939.3
KIAA1324
KIAA1324
chr1_+_179050512 0.19 ENST00000367627.3
TOR3A
torsin family 3, member A
chr6_-_130031358 0.19 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr17_+_66521936 0.18 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr6_+_151042224 0.18 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_-_231560790 0.18 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr19_-_8809139 0.18 ENST00000324436.3
ACTL9
actin-like 9
chr11_-_85565906 0.18 ENST00000544076.1
AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr13_-_20077417 0.18 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr10_+_13628933 0.18 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr3_+_111630451 0.18 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr7_+_80275621 0.17 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr14_-_50319482 0.17 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr1_+_174844645 0.17 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_64023410 0.17 ENST00000447137.2
ZNF680
zinc finger protein 680
chr17_+_48450575 0.17 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr4_+_122722466 0.17 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
EXOSC9
exosome component 9
chr18_+_3466248 0.17 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr7_+_23749945 0.16 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
STK31
serine/threonine kinase 31
chr4_+_170581213 0.16 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_+_201390843 0.16 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chr8_-_27850141 0.15 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr7_+_23749767 0.15 ENST00000355870.3
STK31
serine/threonine kinase 31
chr4_-_148605265 0.15 ENST00000541232.1
ENST00000322396.6
PRMT10
protein arginine methyltransferase 10 (putative)
chr7_+_106505696 0.15 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_78511586 0.15 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr19_+_38085731 0.15 ENST00000589117.1
ZNF540
zinc finger protein 540
chr1_-_150208412 0.15 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_+_21265028 0.15 ENST00000291770.7
ZNF714
zinc finger protein 714
chr20_-_18810797 0.15 ENST00000278779.4
C20orf78
chromosome 20 open reading frame 78
chr2_+_138721850 0.14 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr1_+_219347203 0.14 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr14_-_50319758 0.14 ENST00000298310.5
NEMF
nuclear export mediator factor
chr3_+_101498269 0.14 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr7_+_80275953 0.13 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_-_150208498 0.13 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_-_58571935 0.13 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_102514019 0.13 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr4_-_150736962 0.13 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
RP11-526A4.1
chr19_+_3762645 0.13 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr7_+_106505912 0.13 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr7_-_32534850 0.13 ENST00000409952.3
ENST00000409909.3
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_148508845 0.13 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr2_+_61372226 0.13 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr7_-_27169801 0.13 ENST00000511914.1
HOXA4
homeobox A4
chr16_-_11367452 0.13 ENST00000327157.2
PRM3
protamine 3
chr3_+_122513642 0.12 ENST00000261038.5
DIRC2
disrupted in renal carcinoma 2
chr7_-_16872932 0.12 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr4_+_118955500 0.12 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr15_+_79166065 0.12 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr11_+_61891445 0.12 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr1_-_246580705 0.12 ENST00000541742.1
SMYD3
SET and MYND domain containing 3
chr3_-_123339418 0.12 ENST00000583087.1
MYLK
myosin light chain kinase
chr4_+_128702969 0.12 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chr21_+_47706537 0.12 ENST00000397691.1
YBEY
ybeY metallopeptidase (putative)
chr14_+_24701819 0.12 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chr1_+_219347186 0.12 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr22_+_38142235 0.11 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIOBP
TRIO and F-actin binding protein
chr9_+_40028620 0.11 ENST00000426179.1
AL353791.1
AL353791.1
chr1_+_158979680 0.11 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr14_+_24701628 0.11 ENST00000355299.4
ENST00000559836.1
GMPR2
guanosine monophosphate reductase 2
chr1_+_158979686 0.11 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr19_+_45409011 0.11 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr4_+_88720698 0.11 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr4_-_170533723 0.11 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1
NIMA-related kinase 1
chr14_+_73634537 0.11 ENST00000406768.1
PSEN1
presenilin 1
chr18_-_5544241 0.11 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr3_-_123339343 0.11 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_-_11287243 0.11 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr16_-_18908196 0.11 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr19_-_38085633 0.11 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr16_-_2379688 0.11 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr2_+_48010312 0.10 ENST00000540021.1
MSH6
mutS homolog 6
chr1_-_85097431 0.10 ENST00000327308.3
C1orf180
chromosome 1 open reading frame 180
chr3_+_148545586 0.10 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr2_+_102953608 0.10 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr1_+_50571949 0.10 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr8_-_17555164 0.10 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr4_+_70861647 0.10 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chrX_+_13707235 0.10 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chr15_+_92006567 0.10 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr1_-_220220000 0.10 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr14_+_72052983 0.10 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr14_+_24702099 0.10 ENST00000420554.2
GMPR2
guanosine monophosphate reductase 2
chr17_-_39538550 0.10 ENST00000394001.1
KRT34
keratin 34
chr14_+_24702073 0.10 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr2_+_172778952 0.10 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr5_-_146781153 0.10 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr15_+_69854027 0.10 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr17_-_56769382 0.09 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr4_-_164395014 0.09 ENST00000280605.3
TKTL2
transketolase-like 2
chr3_-_179169181 0.09 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr12_-_91539918 0.09 ENST00000548218.1
DCN
decorin
chr16_+_12059050 0.09 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_-_17513702 0.09 ENST00000428702.2
ENST00000508623.1
ENST00000513615.1
QDPR
quinoid dihydropteridine reductase
chr2_-_225811747 0.09 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr21_+_25801041 0.09 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr5_-_79287060 0.09 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr8_+_118147498 0.08 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr10_+_70847852 0.08 ENST00000242465.3
SRGN
serglycin
chr7_+_80275752 0.08 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_206858232 0.08 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr1_+_90460661 0.08 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
ZNF326
zinc finger protein 326
chr1_-_109656439 0.08 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr19_+_21264980 0.08 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr6_+_29141311 0.08 ENST00000377167.2
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr10_+_90354503 0.08 ENST00000531458.1
LIPJ
lipase, family member J
chr7_+_23749894 0.07 ENST00000433467.2
STK31
serine/threonine kinase 31
chr6_-_51952418 0.07 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr5_+_169010638 0.07 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr11_+_62037622 0.07 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chr6_-_146057144 0.07 ENST00000367519.3
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr10_-_79398250 0.07 ENST00000286627.5
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_+_7011509 0.07 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr4_-_17513851 0.07 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr1_+_46769303 0.07 ENST00000311672.5
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr5_+_138678131 0.07 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr9_-_5304432 0.07 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr16_+_86612112 0.07 ENST00000320241.3
FOXL1
forkhead box L1
chr14_+_24702127 0.07 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr1_-_112106556 0.07 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr4_-_155533787 0.07 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr1_+_55107449 0.07 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
MROH7
maestro heat-like repeat family member 7
chr10_-_69455873 0.07 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_-_114430570 0.07 ENST00000251921.2
NXPE1
neurexophilin and PC-esterase domain family, member 1
chr2_+_33359687 0.07 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr12_-_89413456 0.07 ENST00000500381.2
RP11-13A1.1
RP11-13A1.1
chr7_+_90012986 0.07 ENST00000416322.1
CLDN12
claudin 12
chr11_+_22689648 0.07 ENST00000278187.3
GAS2
growth arrest-specific 2
chr1_-_168464875 0.07 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr1_+_246887349 0.06 ENST00000366510.3
SCCPDH
saccharopine dehydrogenase (putative)
chr22_+_23101182 0.06 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr2_+_138722028 0.06 ENST00000280096.5
HNMT
histamine N-methyltransferase
chrM_+_8527 0.06 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr2_-_37384175 0.06 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr14_-_106725723 0.06 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr5_-_64920115 0.06 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr10_-_51623203 0.06 ENST00000444743.1
ENST00000374065.3
ENST00000374064.3
ENST00000260867.4
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr4_-_175204765 0.06 ENST00000513696.1
ENST00000503293.1
FBXO8
F-box protein 8
chr7_-_30066233 0.06 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr1_+_153631130 0.06 ENST00000368685.5
SNAPIN
SNAP-associated protein
chr6_+_88182643 0.06 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr22_-_19435209 0.06 ENST00000546308.1
ENST00000541063.1
ENST00000399568.1
ENST00000333059.5
HIRA
C22orf39
histone cell cycle regulator
chromosome 22 open reading frame 39
chr13_-_103451307 0.06 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr17_-_17480779 0.06 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr17_-_39140549 0.06 ENST00000377755.4
KRT40
keratin 40
chr9_-_69229650 0.06 ENST00000416428.1
CBWD6
COBW domain containing 6
chr2_+_48796120 0.06 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr11_+_94706804 0.05 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr2_+_33359646 0.05 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_-_165424973 0.05 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr1_+_248402231 0.05 ENST00000306687.1
OR2M4
olfactory receptor, family 2, subfamily M, member 4
chrX_+_49687216 0.05 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr10_+_51371390 0.05 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
TIMM23B
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr6_-_33239712 0.05 ENST00000436044.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr11_-_102576537 0.05 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr11_+_7618413 0.05 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_-_79398127 0.05 ENST00000372443.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_86174065 0.05 ENST00000370574.3
ENST00000431532.2
ZNHIT6
zinc finger, HIT-type containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.9 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.6 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.3 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.6 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.2 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.4 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.3 GO:0032252 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0051344 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.5 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.6 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB