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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXC6_HOXA7

Z-value: 0.47

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Transcription factors associated with HOXC6_HOXA7

Gene Symbol Gene ID Gene Info
ENSG00000197757.7 homeobox C6
ENSG00000122592.6 homeobox A7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA7hg19_v2_chr7_-_27196267_27196311-0.386.0e-02Click!
HOXC6hg19_v2_chr12_+_54422142_54422239-0.048.4e-01Click!

Activity profile of HOXC6_HOXA7 motif

Sorted Z-values of HOXC6_HOXA7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_67418047 2.66 ENST00000540846.2
SMAD family member 3
chr2_+_152214098 0.86 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr11_-_102651343 0.86 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr14_-_101295407 0.72 ENST00000596284.1
AL117190.2
chr7_-_92777606 0.43 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr16_+_12059050 0.40 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr12_+_112279782 0.39 ENST00000550735.2
mitogen-activated protein kinase-activated protein kinase 5
chr18_-_70211691 0.39 ENST00000269503.4
cerebellin 2 precursor
chr17_+_39261584 0.39 ENST00000391415.1
keratin associated protein 4-9
chr12_-_10151773 0.36 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr3_+_111717600 0.36 ENST00000273368.4
transgelin 3
chr3_+_111717511 0.36 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_111718036 0.32 ENST00000455401.2
transgelin 3
chr3_-_191000172 0.31 ENST00000427544.2
urotensin 2B
chrX_+_144908928 0.30 ENST00000408967.2
transmembrane protein 257
chr17_-_76220740 0.29 ENST00000600484.1
Uncharacterized protein
chr1_+_160370344 0.28 ENST00000368061.2
VANGL planar cell polarity protein 2
chr6_+_114178512 0.28 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr4_-_39979576 0.27 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr13_+_32313658 0.27 ENST00000380314.1
ENST00000298386.2
relaxin/insulin-like family peptide receptor 2
chr17_+_1674982 0.26 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_14945933 0.26 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr3_+_138340049 0.26 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr5_+_66300446 0.25 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr18_-_74839891 0.25 ENST00000581878.1
myelin basic protein
chr6_+_26365443 0.24 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chrX_+_9431324 0.24 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr15_-_75748115 0.24 ENST00000360439.4
SIN3 transcription regulator family member A
chr3_+_138340067 0.24 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr12_-_89920030 0.23 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr6_+_26440700 0.23 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr4_+_155484103 0.22 ENST00000302068.4
fibrinogen beta chain
chr9_+_125132803 0.21 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr21_-_43346790 0.21 ENST00000329623.7
C2 calcium-dependent domain containing 2
chr15_+_64680003 0.20 ENST00000261884.3
thyroid hormone receptor interactor 4
chr12_-_91573132 0.20 ENST00000550563.1
ENST00000546370.1
decorin
chr4_+_155484155 0.20 ENST00000509493.1
fibrinogen beta chain
chr2_-_25391468 0.19 ENST00000395826.2
proopiomelanocortin
chr2_-_25391772 0.19 ENST00000405623.1
proopiomelanocortin
chr2_-_25391507 0.19 ENST00000380794.1
proopiomelanocortin
chr2_-_25391425 0.19 ENST00000264708.3
ENST00000449220.1
proopiomelanocortin
chr3_-_194188956 0.19 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr13_-_36050819 0.18 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr8_+_54764346 0.18 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr2_-_40680578 0.18 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr17_-_39623681 0.17 ENST00000225899.3
keratin 32
chr2_+_25015968 0.17 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr2_+_202098203 0.17 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
caspase 8, apoptosis-related cysteine peptidase
chr6_-_36515177 0.17 ENST00000229812.7
serine/threonine kinase 38
chr4_+_169418195 0.16 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr4_-_8873531 0.16 ENST00000400677.3
H6 family homeobox 1
chr11_-_104827425 0.16 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr18_+_5748793 0.16 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr3_+_111718173 0.15 ENST00000494932.1
transgelin 3
chr8_+_70850403 0.15 ENST00000602248.1
Uncharacterized protein
chr4_+_70796784 0.15 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr4_-_119759795 0.15 ENST00000419654.2
SEC24 family member D
chr1_+_225600404 0.14 ENST00000366845.2
AC092811.1
chr11_-_26593677 0.14 ENST00000527569.1
mucin 15, cell surface associated
chr11_+_33061543 0.14 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr5_+_55149150 0.14 ENST00000297015.3
interleukin 31 receptor A
chr11_-_26593779 0.14 ENST00000529533.1
mucin 15, cell surface associated
chr3_+_149191723 0.13 ENST00000305354.4
transmembrane 4 L six family member 4
chr1_+_202317815 0.13 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr2_+_169757750 0.13 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr19_+_55043977 0.13 ENST00000335056.3
killer cell immunoglobulin-like receptor, three domains, X1
chr6_+_26402465 0.13 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chrX_-_130423200 0.12 ENST00000361420.3
immunoglobulin superfamily, member 1
chr4_+_169418255 0.12 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr12_-_89919765 0.12 ENST00000541909.1
ENST00000313546.3
POC1 centriolar protein B
chr1_-_160924589 0.12 ENST00000368029.3
intelectin 2
chr6_-_9933500 0.11 ENST00000492169.1
orofacial cleft 1 candidate 1
chr1_+_202317855 0.11 ENST00000356764.2
protein phosphatase 1, regulatory subunit 12B
chr9_-_215744 0.11 ENST00000382387.2
chromosome 9 open reading frame 66
chr10_-_112678904 0.11 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr5_-_16916624 0.10 ENST00000513882.1
myosin X
chr4_+_71108300 0.10 ENST00000304954.3
casein kappa
chr11_-_107729887 0.10 ENST00000525815.1
solute carrier family 35, member F2
chr6_-_34639733 0.09 ENST00000374021.1
chromosome 6 open reading frame 106
chr4_-_120243545 0.09 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr10_-_112678692 0.08 ENST00000605742.1
BBSome interacting protein 1
chr15_+_69857515 0.08 ENST00000559477.1
RP11-279F6.1
chr1_+_117963209 0.08 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr11_-_121986923 0.08 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr10_+_90660832 0.08 ENST00000371924.1
STAM binding protein-like 1
chr3_+_156799587 0.08 ENST00000469196.1
RP11-6F2.5
chr11_-_5323226 0.08 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr9_-_27005686 0.07 ENST00000380055.5
leucine rich repeat containing 19
chr12_-_91573249 0.07 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr2_+_105050794 0.07 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr2_-_134326009 0.07 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr7_+_134528635 0.07 ENST00000445569.2
caldesmon 1
chr16_-_28634874 0.07 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_+_125133315 0.07 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_46761118 0.07 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chrX_-_77225135 0.07 ENST00000458128.1
phosphoglycerate mutase family member 4
chr16_-_29934558 0.06 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr17_-_4938712 0.06 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr20_+_15177480 0.06 ENST00000402914.1
MACRO domain containing 2
chr15_+_92006567 0.06 ENST00000554333.1
RP11-661P17.1
chr11_-_62911693 0.06 ENST00000417740.1
ENST00000326192.5
solute carrier family 22, member 24
chr14_-_106552755 0.06 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr14_+_56584414 0.06 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr8_-_42623747 0.06 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr6_+_111408698 0.06 ENST00000368851.5
solute carrier family 16 (aromatic amino acid transporter), member 10
chr6_+_30029008 0.06 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
zinc ribbon domain containing 1
chr8_+_24151620 0.06 ENST00000437154.2
ADAM metallopeptidase domain 28
chr2_+_228736335 0.06 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr2_-_128284020 0.05 ENST00000295321.4
ENST00000455721.2
IWS1 homolog (S. cerevisiae)
chr12_-_112279694 0.05 ENST00000443596.1
ENST00000442119.1
MAPKAPK5 antisense RNA 1
chr8_-_41166953 0.05 ENST00000220772.3
secreted frizzled-related protein 1
chr14_+_22465771 0.05 ENST00000390445.2
T cell receptor alpha variable 17
chr2_+_234826016 0.05 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr12_+_26348246 0.05 ENST00000422622.2
sarcospan
chr4_+_108745711 0.05 ENST00000394684.4
sphingomyelin synthase 2
chr7_+_134671234 0.05 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
ATP/GTP binding protein-like 3
chr11_-_63376013 0.05 ENST00000540943.1
phospholipase A2, group XVI
chr7_-_32338917 0.05 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_232651312 0.05 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr2_-_176046391 0.05 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_+_182850743 0.05 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_+_126173647 0.05 ENST00000263579.4
decapping enzyme, scavenger
chr17_-_64225508 0.05 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr7_-_111032971 0.05 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_+_26402517 0.04 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr19_-_54618650 0.04 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr5_+_140625147 0.04 ENST00000231173.3
protocadherin beta 15
chr4_-_87281196 0.04 ENST00000359221.3
mitogen-activated protein kinase 10
chr5_-_86534822 0.04 ENST00000445770.2
Uncharacterized protein
chr8_+_145215928 0.04 ENST00000528919.1
maestro heat-like repeat family member 1
chr4_+_113568207 0.04 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr3_+_157154578 0.04 ENST00000295927.3
pentraxin 3, long
chr3_-_196911002 0.04 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr7_-_22862406 0.04 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr16_+_15489603 0.04 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr6_-_133035185 0.04 ENST00000367928.4
vanin 1
chr11_+_2405833 0.04 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr3_-_164796269 0.04 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr12_+_26348429 0.04 ENST00000242729.2
sarcospan
chr10_+_99205894 0.04 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr1_+_234765057 0.04 ENST00000429269.1
long intergenic non-protein coding RNA 184
chr11_+_59824060 0.04 ENST00000395032.2
ENST00000358152.2
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr10_+_99205959 0.03 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr10_-_99205607 0.03 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr14_-_23058063 0.03 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
defender against cell death 1
chr15_+_58430567 0.03 ENST00000536493.1
aquaporin 9
chr16_-_28937027 0.03 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr7_-_22862448 0.03 ENST00000358435.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr13_-_81801115 0.03 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr7_+_130794846 0.03 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr11_+_59824127 0.03 ENST00000278865.3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr7_+_141811539 0.03 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr4_-_159956333 0.03 ENST00000434826.2
chromosome 4 open reading frame 45
chr7_-_122635754 0.03 ENST00000249284.2
taste receptor, type 2, member 16
chr4_-_46126093 0.03 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr17_-_39324424 0.03 ENST00000391356.2
keratin associated protein 4-3
chr2_+_90211643 0.03 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr19_+_12175504 0.03 ENST00000439326.3
zinc finger protein 844
chr1_-_211307404 0.03 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr7_-_44122063 0.03 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr16_+_28565230 0.03 ENST00000317058.3
coiled-coil domain containing 101
chr3_-_167191814 0.03 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr4_-_87281224 0.02 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr19_-_54619006 0.02 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chrX_-_138724994 0.02 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr12_-_86650077 0.02 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_76398077 0.02 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chr18_-_7117813 0.02 ENST00000389658.3
laminin, alpha 1
chr9_-_5339873 0.02 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr11_-_13517565 0.02 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr12_+_107078474 0.02 ENST00000552866.1
ENST00000229387.5
regulatory factor X, 4 (influences HLA class II expression)
chr2_+_90273679 0.02 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr17_-_39254391 0.02 ENST00000333822.4
keratin associated protein 4-8
chr8_+_77593448 0.02 ENST00000521891.2
zinc finger homeobox 4
chr19_+_54619125 0.02 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr11_-_128894053 0.02 ENST00000392657.3
Rho GTPase activating protein 32
chr1_+_15668240 0.02 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr5_-_126409159 0.02 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
chromosome 5 open reading frame 63
chr11_+_89764274 0.02 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chr17_-_72772462 0.02 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr10_+_90424196 0.01 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
lipase, gastric
chrX_-_16887963 0.01 ENST00000380084.4
retinoblastoma binding protein 7
chr8_+_92261516 0.01 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr12_-_50643664 0.01 ENST00000550592.1
LIM domain and actin binding 1
chr3_-_20053741 0.01 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr4_-_74486109 0.01 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr11_-_26593649 0.01 ENST00000455601.2
mucin 15, cell surface associated
chr8_-_133772794 0.01 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr7_+_148936732 0.01 ENST00000335870.2
zinc finger protein 212
chr12_-_10282742 0.01 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr22_-_41258074 0.01 ENST00000307221.4
DnaJ (Hsp40) homolog, subfamily B, member 7
chrM_+_10053 0.01 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr18_-_47018769 0.01 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr15_+_35270552 0.01 ENST00000391457.2
HCG37415; PRO1914; Uncharacterized protein
chr1_-_190446759 0.01 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr12_-_10282681 0.01 ENST00000533022.1
C-type lectin domain family 7, member A
chr5_-_22853429 0.01 ENST00000504376.2
cadherin 12, type 2 (N-cadherin 2)
chr3_+_132316081 0.01 ENST00000249887.2
atypical chemokine receptor 4
chr5_+_40909354 0.01 ENST00000313164.9
complement component 7
chr11_+_66276550 0.00 ENST00000419755.3
Bardet-Biedl syndrome 1 protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.8 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.3 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.9 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex