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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXC8

Z-value: 0.86

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Transcription factors associated with HOXC8

Gene Symbol Gene ID Gene Info
ENSG00000037965.4 homeobox C8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC8hg19_v2_chr12_+_54402790_54402832-0.164.4e-01Click!

Activity profile of HOXC8 motif

Sorted Z-values of HOXC8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102651343 1.13 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr6_+_53883790 0.93 ENST00000509997.1
muscular LMNA-interacting protein
chr2_+_161993465 0.93 ENST00000457476.1
TRAF family member-associated NFKB activator
chr2_+_89890533 0.88 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr15_+_67418047 0.84 ENST00000540846.2
SMAD family member 3
chr6_+_53883708 0.83 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr12_+_113344755 0.81 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_156693091 0.73 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
cytoplasmic FMR1 interacting protein 2
chr6_+_42847649 0.72 ENST00000424341.2
ENST00000602561.1
ribosomal protein L7-like 1
chr11_+_1718425 0.69 ENST00000382160.1
keratin associated protein 5-6
chrX_+_13671225 0.67 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr1_+_158900568 0.65 ENST00000458222.1
pyrin and HIN domain family, member 1
chr6_-_154751629 0.64 ENST00000424998.1
CNKSR family member 3
chr7_-_22234381 0.63 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_197226875 0.63 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_-_76398077 0.58 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chr1_-_209824643 0.55 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr2_-_225811747 0.55 ENST00000409592.3
dedicator of cytokinesis 10
chr2_+_161993412 0.54 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr15_+_28624878 0.53 ENST00000450328.2
golgin A8 family, member F
chr2_-_202562774 0.52 ENST00000396886.3
ENST00000409143.1
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr12_-_772901 0.49 ENST00000305108.4
ninjurin 2
chr1_+_159409512 0.49 ENST00000423932.3
olfactory receptor, family 10, subfamily J, member 1
chr21_-_15918618 0.49 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_89920030 0.49 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr19_+_45449301 0.48 ENST00000591597.1
apolipoprotein C-II
chr10_+_62538089 0.48 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr3_+_111630451 0.46 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr2_-_202562716 0.46 ENST00000428900.2
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr5_+_135385202 0.46 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr4_-_23735183 0.45 ENST00000507666.1
RP11-380P13.2
chr10_-_90712520 0.44 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr12_+_113354341 0.44 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_90139056 0.43 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr18_+_61445007 0.43 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr4_-_70080449 0.42 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr19_+_41698927 0.42 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr11_+_35198118 0.42 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr10_+_62538248 0.42 ENST00000448257.2
cyclin-dependent kinase 1
chr13_+_34392185 0.41 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr3_+_151531810 0.41 ENST00000232892.7
arylacetamide deacetylase
chr3_+_10206545 0.41 ENST00000256458.4
interleukin-1 receptor-associated kinase 2
chr1_+_144989309 0.41 ENST00000596396.1
Uncharacterized protein
chr6_-_27114577 0.40 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr18_+_61554932 0.39 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr8_-_8318847 0.39 ENST00000521218.1
CTA-398F10.2
chr10_-_4285923 0.39 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr2_-_89630186 0.39 ENST00000390264.2
immunoglobulin kappa variable 2-40
chr12_-_95510743 0.37 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr9_+_131267052 0.37 ENST00000539582.1
GLE1 RNA export mediator
chr19_-_56826157 0.37 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr6_-_52705641 0.37 ENST00000370989.2
glutathione S-transferase alpha 5
chr2_-_89521942 0.36 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr1_-_149783914 0.36 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr6_-_82462425 0.35 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr1_-_243326612 0.35 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
centrosomal protein 170kDa
chr1_-_153085984 0.34 ENST00000468739.1
small proline-rich protein 2F
chr1_+_12851545 0.34 ENST00000332296.7
PRAME family member 1
chr1_-_201438282 0.34 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr12_+_75874580 0.34 ENST00000456650.3
GLI pathogenesis-related 1
chr8_-_38008783 0.33 ENST00000276449.4
steroidogenic acute regulatory protein
chr22_+_21133469 0.33 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr7_-_107443652 0.33 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr10_-_1071796 0.33 ENST00000277517.1
isopentenyl-diphosphate delta isomerase 2
chr17_+_55183261 0.33 ENST00000576295.1
A kinase (PRKA) anchor protein 1
chr12_+_21207503 0.33 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr9_-_21368075 0.32 ENST00000449498.1
interferon, alpha 13
chr2_-_89247338 0.32 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr17_+_66509019 0.32 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_-_14996355 0.32 ENST00000228936.4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr21_-_27423339 0.32 ENST00000415997.1
amyloid beta (A4) precursor protein
chr14_-_94421923 0.32 ENST00000555507.1
ankyrin repeat and SOCS box containing 2
chr6_+_27833034 0.31 ENST00000357320.2
histone cluster 1, H2al
chr19_+_51728316 0.31 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33 molecule
chr11_+_5410607 0.31 ENST00000328611.3
olfactory receptor, family 51, subfamily M, member 1
chr8_+_31497271 0.31 ENST00000520407.1
neuregulin 1
chr5_+_102594403 0.31 ENST00000319933.2
chromosome 5 open reading frame 30
chr14_-_106733624 0.30 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr15_+_79165222 0.30 ENST00000559930.1
mortality factor 4 like 1
chr2_+_162016804 0.30 ENST00000392749.2
ENST00000440506.1
TRAF family member-associated NFKB activator
chr21_-_31744557 0.30 ENST00000399889.2
keratin associated protein 13-2
chr4_+_25314388 0.30 ENST00000302874.4
zinc finger, CCHC domain containing 4
chrM_-_14670 0.30 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chr11_+_35198243 0.29 ENST00000528455.1
CD44 molecule (Indian blood group)
chr17_-_34207295 0.29 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr6_+_27775899 0.29 ENST00000358739.3
histone cluster 1, H2ai
chr5_+_134181625 0.28 ENST00000394976.3
chromosome 5 open reading frame 24
chr7_-_151433393 0.28 ENST00000492843.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_-_169654139 0.28 ENST00000366787.3
thrombospondin 2
chr11_+_5710919 0.28 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr19_+_45449228 0.28 ENST00000252490.4
apolipoprotein C-II
chr7_-_151433342 0.28 ENST00000433631.2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr17_-_62493131 0.27 ENST00000539111.2
polymerase (DNA directed), gamma 2, accessory subunit
chr16_-_46655538 0.27 ENST00000303383.3
SHC SH2-domain binding protein 1
chr3_+_45927994 0.27 ENST00000357632.2
ENST00000395963.2
chemokine (C-C motif) receptor 9
chr11_+_35201826 0.27 ENST00000531873.1
CD44 molecule (Indian blood group)
chr7_+_134528635 0.27 ENST00000445569.2
caldesmon 1
chr20_-_30311703 0.27 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2-like 1
chr8_-_101962777 0.26 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr13_+_100741269 0.26 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
propionyl CoA carboxylase, alpha polypeptide
chr1_-_57045228 0.26 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr3_+_42897512 0.26 ENST00000493193.1
atypical chemokine receptor 2
chr12_-_10978957 0.26 ENST00000240619.2
taste receptor, type 2, member 10
chr3_-_182703688 0.26 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
DCN1, defective in cullin neddylation 1, domain containing 1
chr18_-_70210764 0.26 ENST00000585159.1
ENST00000584764.1
cerebellin 2 precursor
chr3_-_197024965 0.26 ENST00000392382.2
discs, large homolog 1 (Drosophila)
chr17_-_38938786 0.26 ENST00000301656.3
keratin 27
chr7_-_22233442 0.26 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr11_+_6947720 0.26 ENST00000414517.2
zinc finger protein 215
chr2_+_201994042 0.26 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr10_+_13652047 0.26 ENST00000601460.1
Uncharacterized protein
chr7_+_20687017 0.25 ENST00000258738.6
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr12_-_12491608 0.25 ENST00000545735.1
MANSC domain containing 1
chr6_-_26199471 0.25 ENST00000341023.1
histone cluster 1, H2ad
chrX_+_150869023 0.25 ENST00000448324.1
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr6_-_26235206 0.25 ENST00000244534.5
histone cluster 1, H1d
chr12_-_15104040 0.25 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr18_+_48918368 0.25 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
chr6_-_47009996 0.25 ENST00000371243.2
G protein-coupled receptor 110
chr2_+_90248739 0.25 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr16_-_46865286 0.25 ENST00000285697.4
chromosome 16 open reading frame 87
chr11_-_128457446 0.24 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr3_+_30647994 0.24 ENST00000295754.5
transforming growth factor, beta receptor II (70/80kDa)
chr2_+_183989157 0.24 ENST00000541912.1
nucleoporin 35kDa
chr13_-_46679144 0.24 ENST00000181383.4
carboxypeptidase B2 (plasma)
chrY_+_2709527 0.24 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr10_+_5238793 0.24 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr9_+_133274029 0.24 ENST00000277491.7
AL354898.1
chr8_-_27695552 0.24 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr5_-_94890648 0.24 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr2_+_234600253 0.24 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_168043793 0.24 ENST00000409273.1
ENST00000409605.1
xin actin-binding repeat containing 2
chr13_-_46679185 0.24 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr1_-_85930246 0.24 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr3_+_111717511 0.24 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr1_+_11724167 0.24 ENST00000376753.4
F-box protein 6
chr3_-_197025447 0.23 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
discs, large homolog 1 (Drosophila)
chr11_-_18610246 0.23 ENST00000379387.4
ENST00000541984.1
UEV and lactate/malate dehyrogenase domains
chr2_+_201997676 0.23 ENST00000462763.1
ENST00000479953.2
CASP8 and FADD-like apoptosis regulator
chr2_-_89399845 0.23 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr3_-_120461353 0.23 ENST00000483733.1
RAB, member of RAS oncogene family-like 3
chr4_-_84255935 0.23 ENST00000513463.1
heparanase
chr19_-_14945933 0.23 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr8_-_135522425 0.23 ENST00000521673.1
zinc finger and AT hook domain containing
chr2_+_183989083 0.23 ENST00000295119.4
nucleoporin 35kDa
chr5_+_138609441 0.22 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr16_-_11681023 0.22 ENST00000570904.1
ENST00000574701.1
lipopolysaccharide-induced TNF factor
chr1_+_101702417 0.22 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr15_+_66994561 0.22 ENST00000288840.5
SMAD family member 6
chr3_+_101818088 0.22 ENST00000491959.1
zona pellucida-like domain containing 1
chr2_-_201753980 0.22 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
peptidylprolyl isomerase (cyclophilin)-like 3
chr11_-_18956556 0.22 ENST00000302797.3
MAS-related GPR, member X1
chr11_-_7847519 0.22 ENST00000328375.1
olfactory receptor, family 5, subfamily P, member 3
chr14_-_105420241 0.22 ENST00000557457.1
AHNAK nucleoprotein 2
chr1_+_87012753 0.22 ENST00000370563.3
chloride channel accessory 4
chr19_-_10697895 0.22 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr9_+_470288 0.22 ENST00000382303.1
KN motif and ankyrin repeat domains 1
chr9_-_97090926 0.22 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUT family member 2F
chr22_+_23487513 0.22 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr2_+_79347577 0.22 ENST00000233735.1
regenerating islet-derived 1 alpha
chr12_+_22199108 0.22 ENST00000229329.2
cytidine monophosphate N-acetylneuraminic acid synthetase
chr6_-_44281043 0.22 ENST00000244571.4
alanyl-tRNA synthetase 2, mitochondrial
chr11_+_55578854 0.22 ENST00000333973.2
olfactory receptor, family 5, subfamily L, member 1
chr8_+_104310661 0.22 ENST00000522566.1
frizzled family receptor 6
chr3_-_157251383 0.22 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr12_-_102455846 0.21 ENST00000545679.1
coiled-coil domain containing 53
chr21_-_43735628 0.21 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr19_+_45844032 0.21 ENST00000589837.1
kinesin light chain 3
chr3_+_111451321 0.21 ENST00000393923.3
pleckstrin homology-like domain, family B, member 2
chr12_+_51236703 0.21 ENST00000551456.1
ENST00000398458.3
transmembrane (C-terminal) protease, serine 12
chr2_+_143886877 0.21 ENST00000295095.6
Rho GTPase activating protein 15
chr13_-_103019744 0.21 ENST00000437115.2
FGF14 intronic transcript 1 (non-protein coding)
chr15_-_56757329 0.21 ENST00000260453.3
meiosis-specific nuclear structural 1
chr2_-_111435610 0.21 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1 mitotic checkpoint serine/threonine kinase
chr7_-_128415844 0.21 ENST00000249389.2
opsin 1 (cone pigments), short-wave-sensitive
chr5_-_146781153 0.21 ENST00000520473.1
dihydropyrimidinase-like 3
chr1_+_110993795 0.21 ENST00000271331.3
prokineticin 1
chrX_+_30261847 0.21 ENST00000378981.3
ENST00000397550.1
melanoma antigen family B, 1
chrX_-_41782592 0.21 ENST00000378158.1
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr16_+_89696692 0.21 ENST00000261615.4
dipeptidase 1 (renal)
chr14_+_52164820 0.21 ENST00000554167.1
FERM domain containing 6
chr4_+_122722466 0.20 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr14_-_106539557 0.20 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr19_+_42301079 0.20 ENST00000596544.1
carcinoembryonic antigen-related cell adhesion molecule 3
chr12_-_54652060 0.20 ENST00000552562.1
chromobox homolog 5
chr15_+_52155001 0.20 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr2_-_177502254 0.20 ENST00000339037.3
long intergenic non-protein coding RNA 1116
chr2_+_242811874 0.20 ENST00000343216.3
CXXC finger protein 11
chr4_-_104119528 0.20 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr8_+_104892639 0.20 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr10_+_96522361 0.20 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr6_-_32498046 0.20 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr18_+_3466248 0.20 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr1_+_207262881 0.20 ENST00000451804.2
complement component 4 binding protein, beta
chr2_+_216176540 0.20 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr12_-_102455902 0.20 ENST00000240079.6
coiled-coil domain containing 53
chrX_+_41548220 0.19 ENST00000378142.4
G protein-coupled receptor 34
chr4_+_79472673 0.19 ENST00000264908.6
annexin A3
chr2_+_201450591 0.19 ENST00000374700.2
aldehyde oxidase 1
chr1_-_52456352 0.19 ENST00000371655.3
RAB3B, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.9 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.9 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 1.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0070859 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.4 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.2 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.2 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.1 GO:0032672 regulation of interleukin-3 production(GO:0032672)
0.1 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0019087 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.0 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.2 GO:0051586 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.7 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0090647 modulation of age-related behavioral decline(GO:0090647)
0.0 0.0 GO:0002652 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.4 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.6 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 2.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.3 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.0 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.7 GO:0010965 regulation of mitotic sister chromatid separation(GO:0010965)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.6 GO:0043219 lateral loop(GO:0043219)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.9 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.7 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.7 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases