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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HOXD10

Z-value: 0.65

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.5 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_176981307-0.628.5e-04Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_74675521 1.28 ENST00000377024.3
chromosome 9 open reading frame 57
chr18_+_48918368 1.28 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
chr6_+_147527103 1.18 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr18_-_22932080 1.04 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
zinc finger protein 521
chr3_-_64211112 0.94 ENST00000295902.6
prickle homolog 2 (Drosophila)
chr8_+_124084899 0.92 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr13_+_114567131 0.90 ENST00000608651.1
GAS6 antisense RNA 2 (head to head)
chr2_-_188312971 0.85 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr1_+_78470530 0.79 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr12_-_10022735 0.73 ENST00000228438.2
C-type lectin domain family 2, member B
chr1_+_158978768 0.71 ENST00000447473.2
interferon, gamma-inducible protein 16
chr9_-_47314222 0.67 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
chr1_-_76398077 0.67 ENST00000284142.6
ankyrin repeat and SOCS box containing 17
chr12_+_20963632 0.63 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr20_-_17539456 0.63 ENST00000544874.1
ENST00000377868.2
beaded filament structural protein 1, filensin
chr1_+_164528866 0.62 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr12_+_20963647 0.62 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr3_+_43328004 0.62 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNF related kinase
chr2_-_165424973 0.61 ENST00000543549.1
growth factor receptor-bound protein 14
chr4_+_86748898 0.61 ENST00000509300.1
Rho GTPase activating protein 24
chr18_-_25616519 0.58 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_89951028 0.57 ENST00000506913.1
family with sequence similarity 13, member A
chr14_-_106453155 0.56 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr12_-_76817036 0.56 ENST00000546946.1
oxysterol binding protein-like 8
chr5_-_55529115 0.55 ENST00000513241.2
ENST00000341048.4
ankyrin repeat domain 55
chr8_-_95274536 0.55 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr1_-_149459549 0.54 ENST00000369175.3
family with sequence similarity 72, member C
chr8_+_74903580 0.49 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr2_-_190627481 0.48 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
O-sialoglycoprotein endopeptidase-like 1
chr9_+_75263565 0.47 ENST00000396237.3
transmembrane channel-like 1
chr3_+_107318157 0.47 ENST00000406780.1
bobby sox homolog (Drosophila)
chr21_-_35016231 0.47 ENST00000438788.1
crystallin, zeta (quinone reductase)-like 1
chr2_-_89521942 0.46 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr1_+_62439037 0.46 ENST00000545929.1
InaD-like (Drosophila)
chr2_+_47630255 0.44 ENST00000406134.1
mutS homolog 2
chr10_-_52008313 0.43 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr1_+_40713573 0.42 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr4_+_108910870 0.42 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chr14_-_20774092 0.42 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
tetratricopeptide repeat domain 5
chr10_+_94594351 0.42 ENST00000371552.4
exocyst complex component 6
chr6_+_96025341 0.42 ENST00000369293.1
ENST00000358812.4
mannosidase, endo-alpha
chr12_-_71148413 0.42 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
protein tyrosine phosphatase, receptor type, R
chr12_-_71148357 0.41 ENST00000378778.1
protein tyrosine phosphatase, receptor type, R
chr4_+_77356248 0.41 ENST00000296043.6
shroom family member 3
chr5_+_131892603 0.40 ENST00000378823.3
ENST00000265335.6
RAD50 homolog (S. cerevisiae)
chr13_-_67802549 0.40 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr4_+_86749045 0.38 ENST00000514229.1
Rho GTPase activating protein 24
chr13_+_33160553 0.38 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr20_+_59654146 0.36 ENST00000441660.1
RP5-827L5.1
chr11_+_22689648 0.36 ENST00000278187.3
growth arrest-specific 2
chr4_-_90758227 0.36 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
synuclein, alpha (non A4 component of amyloid precursor)
chr12_-_100656134 0.35 ENST00000548313.1
DEP domain containing 4
chr3_+_186435065 0.35 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr2_+_88047606 0.34 ENST00000359481.4
plasminogen-like B2
chr3_+_169629354 0.34 ENST00000428432.2
ENST00000335556.3
sterile alpha motif domain containing 7
chr1_+_79115503 0.34 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chrX_-_8139308 0.34 ENST00000317103.4
variable charge, X-linked 2
chr4_+_40198527 0.33 ENST00000381799.5
ras homolog family member H
chr1_-_232598163 0.33 ENST00000308942.4
signal-induced proliferation-associated 1 like 2
chr1_+_78383813 0.33 ENST00000342754.5
nexilin (F actin binding protein)
chr16_-_30122717 0.33 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr4_-_102268628 0.33 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_75229616 0.32 ENST00000340019.3
transmembrane channel-like 1
chr6_+_132455118 0.31 ENST00000458028.1
long intergenic non-protein coding RNA 1013
chr15_+_57511609 0.31 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr4_-_102268484 0.31 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_+_79258547 0.31 ENST00000457153.2
synaptotagmin I
chr16_-_71610985 0.30 ENST00000355962.4
tyrosine aminotransferase
chr15_+_76352178 0.30 ENST00000388942.3
chromosome 15 open reading frame 27
chr6_-_76072719 0.30 ENST00000370020.1
filamin A interacting protein 1
chr3_-_157221128 0.30 ENST00000392833.2
ENST00000362010.2
ventricular zone expressed PH domain-containing 1
chr2_+_89998789 0.30 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr6_-_8102714 0.29 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr2_-_211341411 0.29 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr7_+_135611542 0.29 ENST00000416501.1
AC015987.2
chr11_+_7110165 0.29 ENST00000306904.5
RNA binding motif protein, X-linked-like 2
chr9_+_27109133 0.29 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr11_+_63137251 0.29 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr11_-_77791156 0.28 ENST00000281031.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr2_+_207804278 0.28 ENST00000272852.3
carboxypeptidase O
chrX_+_10031499 0.28 ENST00000454666.1
WWC family member 3
chr5_+_140227048 0.28 ENST00000532602.1
protocadherin alpha 9
chr6_+_24667257 0.28 ENST00000537591.1
ENST00000230048.4
acyl-CoA thioesterase 13
chr9_-_130517522 0.27 ENST00000373274.3
ENST00000420366.1
SH2 domain containing 3C
chr11_+_120255997 0.27 ENST00000532993.1
Rho guanine nucleotide exchange factor (GEF) 12
chr2_-_130902567 0.26 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
coiled-coil domain containing 74B
chr1_+_186798073 0.26 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr1_+_207262881 0.26 ENST00000451804.2
complement component 4 binding protein, beta
chr15_+_48498480 0.26 ENST00000380993.3
ENST00000396577.3
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr12_-_7656357 0.25 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr12_-_118797475 0.25 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr6_+_121756809 0.25 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chrX_+_37639302 0.25 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr6_-_119031228 0.24 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr6_+_166945369 0.24 ENST00000598601.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr1_-_231560790 0.24 ENST00000366641.3
egl-9 family hypoxia-inducible factor 1
chr14_+_22771851 0.24 ENST00000390466.1
T cell receptor alpha variable 39
chrX_+_107334895 0.24 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr1_+_15986364 0.24 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr16_-_15736881 0.23 ENST00000540441.2
KIAA0430
chr17_+_48823896 0.23 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr1_-_153113927 0.23 ENST00000368752.4
small proline-rich protein 2B
chr5_+_140254884 0.23 ENST00000398631.2
protocadherin alpha 12
chr12_+_8309630 0.23 ENST00000396570.3
zinc finger protein 705A
chr5_-_111312622 0.23 ENST00000395634.3
neuronal regeneration related protein
chr19_-_44388116 0.23 ENST00000587539.1
zinc finger protein 404
chr5_-_36152031 0.22 ENST00000296603.4
LMBR1 domain containing 2
chr7_+_77469439 0.22 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr10_-_120925054 0.22 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
sideroflexin 4
chr15_+_41099254 0.22 ENST00000570108.1
ENST00000564258.1
ENST00000355341.4
ENST00000336455.5
zinc finger, FYVE domain containing 19
chr10_+_116697946 0.22 ENST00000298746.3
TruB pseudouridine (psi) synthase family member 1
chr18_+_3252206 0.22 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_118814344 0.22 ENST00000397564.2
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr8_+_26150628 0.22 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr18_+_6729698 0.22 ENST00000383472.4
Rho GTPase activating protein 28
chr5_-_122759032 0.22 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
centrosomal protein 120kDa
chr11_+_112047087 0.22 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr13_+_76378305 0.21 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr12_+_118814185 0.21 ENST00000543473.1
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr11_-_31531121 0.21 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr9_+_42671887 0.21 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr1_+_206972215 0.20 ENST00000340758.2
interleukin 19
chr7_+_107224364 0.20 ENST00000491150.1
B-cell receptor-associated protein 29
chr7_-_7782204 0.20 ENST00000418534.2
AC007161.5
chr10_+_124739964 0.20 ENST00000406217.2
phosphoseryl-tRNA kinase
chrX_+_10124977 0.20 ENST00000380833.4
chloride channel, voltage-sensitive 4
chr6_-_29324054 0.20 ENST00000543825.1
olfactory receptor, family 5, subfamily V, member 1
chr12_-_10324716 0.20 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr14_-_82089405 0.20 ENST00000554211.1
RP11-799P8.1
chr1_-_243326612 0.19 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
centrosomal protein 170kDa
chr12_+_16109519 0.19 ENST00000526530.1
deoxyribose-phosphate aldolase (putative)
chr1_+_41204506 0.19 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
nuclear transcription factor Y, gamma
chr11_-_77790865 0.19 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFC2-KCTD14 readthrough
chr10_+_695888 0.19 ENST00000441152.2
proline rich 26
chr6_-_15586238 0.19 ENST00000462989.2
dystrobrevin binding protein 1
chr1_+_174844645 0.18 ENST00000486220.1
RAB GTPase activating protein 1-like
chr9_+_70856397 0.18 ENST00000360171.6
COBW domain containing 3
chr12_-_11214893 0.18 ENST00000533467.1
taste receptor, type 2, member 46
chr12_-_9102549 0.18 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr10_+_124739911 0.18 ENST00000405485.1
phosphoseryl-tRNA kinase
chr18_+_3252265 0.17 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr8_+_21823726 0.17 ENST00000433566.4
exportin 7
chr8_-_124279627 0.17 ENST00000357082.4
ZHX1-C8ORF76 readthrough
chr4_+_130017268 0.17 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr2_-_87248975 0.17 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr5_-_135290705 0.17 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr10_+_35456444 0.16 ENST00000361599.4
cAMP responsive element modulator
chr3_+_35721182 0.16 ENST00000413378.1
ENST00000417925.1
cAMP-regulated phosphoprotein, 21kDa
chr10_+_5488564 0.16 ENST00000449083.1
ENST00000380359.3
neuroepithelial cell transforming 1
chr6_-_160679905 0.16 ENST00000366953.3
solute carrier family 22 (organic cation transporter), member 2
chr13_+_76378357 0.16 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr5_-_111754948 0.16 ENST00000261486.5
erythrocyte membrane protein band 4.1 like 4A
chr11_-_110583912 0.16 ENST00000533353.1
ENST00000527598.1
Rho GTPase activating protein 20
chr6_-_26250835 0.16 ENST00000446824.2
histone cluster 1, H3f
chr18_-_10701979 0.16 ENST00000538948.1
ENST00000285141.4
piezo-type mechanosensitive ion channel component 2
chr11_-_124180733 0.16 ENST00000357821.2
olfactory receptor, family 8, subfamily D, member 1
chr6_+_28317685 0.16 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr4_-_90756769 0.16 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_64064748 0.15 ENST00000381070.3
ENST00000508024.1
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr1_-_156399184 0.15 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr8_-_101719159 0.15 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr11_-_102576537 0.15 ENST00000260229.4
matrix metallopeptidase 27
chr11_-_104769141 0.15 ENST00000508062.1
ENST00000422698.2
caspase 12 (gene/pseudogene)
chr1_+_248185250 0.15 ENST00000355281.1
olfactory receptor, family 2, subfamily L, member 5
chr1_-_54405773 0.15 ENST00000371376.1
heat shock protein family B (small), member 11
chr3_+_186435137 0.15 ENST00000447445.1
kininogen 1
chr9_-_95166841 0.14 ENST00000262551.4
osteoglycin
chr16_+_57481382 0.14 ENST00000564655.1
ENST00000567072.1
ENST00000567933.1
ENST00000563166.1
coenzyme Q9
chr6_+_25963020 0.14 ENST00000357085.3
tripartite motif containing 38
chr6_-_150067696 0.14 ENST00000340413.2
ENST00000367403.3
nucleoporin 43kDa
chr1_+_207277590 0.14 ENST00000367070.3
complement component 4 binding protein, alpha
chr3_-_126327398 0.14 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr11_+_18433840 0.14 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr5_+_122181128 0.14 ENST00000261369.4
sorting nexin 24
chr12_+_60083118 0.14 ENST00000261187.4
ENST00000543448.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_+_158288999 0.14 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
myeloid leukemia factor 1
chr6_-_20212630 0.14 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
membrane bound O-acyltransferase domain containing 1
chr9_+_108006880 0.14 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
solute carrier family 44 (choline transporter), member 1
chr3_-_185538849 0.14 ENST00000421047.2
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_53770972 0.13 ENST00000311170.4
vomeronasal 1 receptor 4
chr3_-_128206759 0.13 ENST00000430265.2
GATA binding protein 2
chr4_+_166300084 0.13 ENST00000402744.4
carboxypeptidase E
chr18_+_61445007 0.13 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr15_+_71389281 0.13 ENST00000355327.3
thrombospondin, type I, domain containing 4
chrX_-_41449204 0.13 ENST00000378179.3
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr1_-_242162375 0.13 ENST00000357246.3
microtubule-associated protein 1 light chain 3 gamma
chr6_+_158733692 0.13 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr8_+_39770803 0.13 ENST00000518237.1
indoleamine 2,3-dioxygenase 1
chr4_-_84035905 0.13 ENST00000311507.4
placenta-specific 8
chr18_+_46065393 0.13 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr6_-_132967142 0.12 ENST00000275216.1
trace amine associated receptor 1
chr1_-_89736434 0.12 ENST00000370459.3
guanylate binding protein 5
chr16_+_20499024 0.12 ENST00000593357.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr5_+_118407053 0.12 ENST00000311085.8
ENST00000539542.1
Dmx-like 1
chr5_-_137475071 0.12 ENST00000265191.2
NME/NM23 family member 5
chr4_+_78804393 0.12 ENST00000502384.1
mitochondrial ribosomal protein L1
chr1_+_244214577 0.12 ENST00000358704.4
zinc finger and BTB domain containing 18
chr18_-_19997878 0.12 ENST00000391403.2
cutaneous T-cell lymphoma-associated antigen 1
chr9_+_4839762 0.12 ENST00000448872.2
ENST00000441844.1
RNA terminal phosphate cyclase-like 1
chr7_+_90338712 0.12 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.5 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.3 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.9 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.4 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.4 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0071284 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0032252 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.2 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.1 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.0 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.6 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0042311 vasodilation(GO:0042311)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation