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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HSF2

Z-value: 0.65

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Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
HSF2
ENSG00000025156.8 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF2hg19_v2_chr6_+_122720681_122720713-0.183.8e-01Click!

Activity profile of HSF2 motif

Sorted Z-values of HSF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_30960915 1.51 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr8_-_81083341 1.30 ENST00000519303.2
TPD52
tumor protein D52
chr6_+_149539767 1.11 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr8_-_81083890 0.95 ENST00000518937.1
TPD52
tumor protein D52
chr4_-_186877806 0.88 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr5_+_118691706 0.79 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr4_-_186877502 0.71 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chrX_+_135279179 0.70 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr8_-_81083731 0.70 ENST00000379096.5
TPD52
tumor protein D52
chr9_+_33025209 0.65 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chrX_+_135230712 0.63 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr15_-_70388599 0.59 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr19_-_14628645 0.58 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chrX_+_135278908 0.57 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr7_+_75931861 0.56 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr11_+_12695944 0.53 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr15_-_70388943 0.53 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr5_+_56469843 0.51 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr2_-_188419078 0.51 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_123011476 0.50 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr18_-_52989217 0.49 ENST00000570287.2
TCF4
transcription factor 4
chr17_+_56315936 0.46 ENST00000543544.1
LPO
lactoperoxidase
chr5_+_56469939 0.46 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr5_+_56469775 0.45 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr2_-_188419200 0.44 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_10007448 0.43 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr11_+_46316677 0.42 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr12_-_14721283 0.42 ENST00000240617.5
PLBD1
phospholipase B domain containing 1
chr11_+_117063295 0.42 ENST00000525478.1
ENST00000532062.1
SIDT2
SID1 transmembrane family, member 2
chr11_-_71791518 0.41 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chr7_+_130126165 0.41 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr7_+_130126012 0.40 ENST00000341441.5
MEST
mesoderm specific transcript
chr11_-_71791726 0.40 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr3_-_64673668 0.39 ENST00000498707.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr17_-_79817091 0.37 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chrX_-_30993201 0.36 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr18_-_812231 0.36 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr12_+_2904102 0.33 ENST00000001008.4
FKBP4
FK506 binding protein 4, 59kDa
chr3_-_112360116 0.33 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr6_+_44215603 0.33 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr12_+_69979210 0.32 ENST00000544368.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr6_+_29364416 0.32 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr5_-_112770674 0.31 ENST00000390666.3
TSSK1B
testis-specific serine kinase 1B
chr18_-_52989525 0.31 ENST00000457482.3
TCF4
transcription factor 4
chr6_+_31783291 0.30 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A
heat shock 70kDa protein 1A
chr7_+_23637763 0.29 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr2_-_85581623 0.28 ENST00000449375.1
ENST00000409984.2
ENST00000457495.2
ENST00000263854.6
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr2_-_178128250 0.28 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_-_151936416 0.28 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_-_123011536 0.27 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr4_-_6383594 0.27 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr2_+_28615669 0.26 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr5_+_79331164 0.26 ENST00000350881.2
THBS4
thrombospondin 4
chr19_-_14629224 0.26 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_+_74648848 0.25 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54
WD repeat domain 54
chr4_-_22517620 0.25 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr14_+_103800513 0.25 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr12_+_69979113 0.24 ENST00000299300.6
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr12_+_11802753 0.24 ENST00000396373.4
ETV6
ets variant 6
chr3_-_183735651 0.24 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_+_65134088 0.23 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr12_+_69979446 0.22 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr8_+_134125727 0.22 ENST00000521107.1
TG
thyroglobulin
chr11_+_86013253 0.22 ENST00000533986.1
ENST00000278483.3
C11orf73
chromosome 11 open reading frame 73
chr11_-_414948 0.22 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr7_-_4901625 0.22 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chr2_-_97405775 0.22 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chrX_-_107225600 0.21 ENST00000302917.1
TEX13B
testis expressed 13B
chr5_-_159739532 0.21 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr6_+_32709119 0.21 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr2_-_85581701 0.21 ENST00000295802.4
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr9_+_91926103 0.21 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr6_-_155635583 0.21 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr6_-_53013620 0.20 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr2_+_219824357 0.20 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr13_+_24144796 0.19 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr19_-_49522727 0.19 ENST00000600007.1
CTB-60B18.10
CTB-60B18.10
chr17_-_74137374 0.18 ENST00000322957.6
FOXJ1
forkhead box J1
chr13_+_24144509 0.18 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr7_-_26240357 0.18 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr13_+_46276441 0.17 ENST00000310521.1
ENST00000533564.1
SPERT
spermatid associated
chr20_+_57427765 0.17 ENST00000371100.4
GNAS
GNAS complex locus
chr7_-_33080506 0.17 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr17_-_76573465 0.17 ENST00000585328.1
ENST00000389840.5
DNAH17
dynein, axonemal, heavy chain 17
chr14_+_89060749 0.16 ENST00000555900.1
ENST00000406216.3
ENST00000557737.1
ZC3H14
zinc finger CCCH-type containing 14
chr15_+_36338242 0.16 ENST00000560056.1
RP11-684B21.1
RP11-684B21.1
chr12_-_45269430 0.16 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr10_+_120116527 0.16 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr17_-_56494908 0.16 ENST00000577716.1
RNF43
ring finger protein 43
chr13_-_31736132 0.16 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr6_+_106534192 0.16 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr7_-_14880892 0.15 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chrX_-_51239425 0.15 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_+_65770227 0.15 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr9_+_34989638 0.15 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr17_-_56494882 0.15 ENST00000584437.1
RNF43
ring finger protein 43
chr14_+_89060739 0.15 ENST00000318308.6
ZC3H14
zinc finger CCCH-type containing 14
chr7_+_132333553 0.14 ENST00000332558.4
AC009365.3
AC009365.3
chr11_+_12696102 0.14 ENST00000527636.1
ENST00000527376.1
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr15_-_43785274 0.14 ENST00000413546.1
TP53BP1
tumor protein p53 binding protein 1
chr19_-_49560987 0.14 ENST00000596965.1
CGB7
chorionic gonadotropin, beta polypeptide 7
chr17_-_56494713 0.13 ENST00000407977.2
RNF43
ring finger protein 43
chr21_+_35445811 0.13 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr12_-_45270077 0.13 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr3_+_39509070 0.13 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr11_+_65769946 0.13 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr4_+_123161120 0.13 ENST00000446180.1
KIAA1109
KIAA1109
chr13_-_31736478 0.13 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr20_+_4666882 0.13 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr7_+_142378566 0.12 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr18_+_3451584 0.12 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr2_-_10978103 0.12 ENST00000404824.2
PDIA6
protein disulfide isomerase family A, member 6
chr20_+_31755934 0.12 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr20_+_61867235 0.12 ENST00000342412.6
ENST00000217169.3
BIRC7
baculoviral IAP repeat containing 7
chr11_+_65769550 0.12 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr2_-_197226875 0.12 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr22_+_40297079 0.11 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chr11_+_66276550 0.11 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr18_+_3451646 0.11 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr8_-_141931287 0.11 ENST00000517887.1
PTK2
protein tyrosine kinase 2
chr6_-_53213780 0.11 ENST00000304434.6
ENST00000370918.4
ELOVL5
ELOVL fatty acid elongase 5
chr9_-_4666337 0.11 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr4_-_159644507 0.11 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr2_-_152589670 0.10 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr17_+_7608511 0.10 ENST00000226091.2
EFNB3
ephrin-B3
chr12_+_54891495 0.10 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr19_+_54606145 0.10 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr22_+_40297105 0.10 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chr3_-_183735731 0.10 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_-_36781352 0.10 ENST00000416516.2
DCLK3
doublecortin-like kinase 3
chr17_+_73663402 0.09 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr9_-_4666421 0.09 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr1_+_192544857 0.09 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr14_-_57277178 0.09 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr4_+_154387480 0.08 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr20_+_33292068 0.08 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr6_+_32121218 0.08 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr6_-_32339649 0.08 ENST00000527965.1
ENST00000532023.1
ENST00000447241.2
ENST00000375007.4
ENST00000534588.1
C6orf10
chromosome 6 open reading frame 10
chr1_+_168195229 0.07 ENST00000271375.4
ENST00000367825.3
SFT2D2
SFT2 domain containing 2
chr6_-_32339671 0.07 ENST00000442822.2
ENST00000375015.4
ENST00000533191.1
C6orf10
chromosome 6 open reading frame 10
chr15_+_78556428 0.07 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_120629653 0.07 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr11_-_122932730 0.07 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr1_-_168698433 0.07 ENST00000367817.3
DPT
dermatopontin
chr10_-_1246317 0.07 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr10_+_104535994 0.06 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr8_-_120605194 0.06 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_-_82997420 0.06 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr11_+_75273246 0.06 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_+_75273101 0.06 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chrX_-_101718085 0.06 ENST00000372750.1
ENST00000372752.1
NXF2B
nuclear RNA export factor 2B
chr5_-_35089722 0.05 ENST00000511486.1
ENST00000310101.5
ENST00000231423.3
ENST00000513753.1
ENST00000348262.3
ENST00000397391.3
ENST00000542609.1
PRLR
prolactin receptor
chr13_-_20805109 0.05 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr11_-_65769594 0.05 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chr15_-_81616446 0.05 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr21_-_30445886 0.05 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr3_+_158787041 0.05 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr21_+_45148735 0.05 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr14_+_93357749 0.05 ENST00000557689.1
RP11-862G15.1
RP11-862G15.1
chr17_-_71410794 0.05 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr19_+_1438383 0.05 ENST00000586686.2
ENST00000591032.1
ENST00000586656.1
ENST00000589656.2
ENST00000593052.1
ENST00000586096.2
ENST00000591804.2
RPS15
ribosomal protein S15
chr6_+_41303372 0.04 ENST00000373083.4
ENST00000373089.5
ENST00000373086.3
NCR2
natural cytotoxicity triggering receptor 2
chr14_-_25479811 0.04 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr19_-_55691614 0.04 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr13_-_31736027 0.04 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr6_+_32121789 0.04 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr18_+_3449821 0.04 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr19_+_1438351 0.04 ENST00000233609.4
RPS15
ribosomal protein S15
chrX_+_101478829 0.04 ENST00000372763.1
ENST00000372758.1
NXF2
nuclear RNA export factor 2
chr1_-_228613026 0.04 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr6_+_32121908 0.04 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr2_+_198365122 0.03 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr3_+_96533413 0.03 ENST00000470610.2
ENST00000389672.5
EPHA6
EPH receptor A6
chr6_+_31795506 0.03 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr15_+_78556809 0.03 ENST00000343789.3
ENST00000394852.3
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr19_+_782755 0.03 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr6_-_123957942 0.03 ENST00000398178.3
TRDN
triadin
chr3_-_49131013 0.03 ENST00000424300.1
QRICH1
glutamine-rich 1
chr10_+_135340859 0.03 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr15_+_96869165 0.03 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_+_58138800 0.02 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31
tetraspanin 31
chr3_+_39509163 0.02 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr8_+_87878640 0.02 ENST00000518476.1
CNBD1
cyclic nucleotide binding domain containing 1
chr7_-_150652924 0.02 ENST00000330883.4
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_-_123958141 0.02 ENST00000334268.4
TRDN
triadin
chr11_+_27062502 0.02 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_-_216596738 0.01 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr3_-_185655795 0.01 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B
transformer 2 beta homolog (Drosophila)
chr16_+_55600580 0.01 ENST00000457326.2
CAPNS2
calpain, small subunit 2
chrX_+_106163626 0.01 ENST00000336803.1
CLDN2
claudin 2
chr19_+_14142535 0.01 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr3_-_48632593 0.01 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr1_+_151171012 0.01 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr4_-_107957454 0.01 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr11_+_27062860 0.01 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_55691472 0.00 ENST00000537500.1
SYT5
synaptotagmin V
chrX_-_102941596 0.00 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chr11_+_71791693 0.00 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr14_-_94970559 0.00 ENST00000556881.1
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr14_-_77889860 0.00 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0035378 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.3 0.8 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3 0.8 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.6 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.0 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.2 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078) regulation of NK T cell differentiation(GO:0051136)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 1.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 1.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.7 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 3.0 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3 0.8 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 1.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0031403 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 3.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse