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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for HSFY2

Z-value: 0.56

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Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_209356210.222.8e-01Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_49860525 0.66 ENST00000435790.2
Rho GTPase activating protein 22
chr2_-_169769787 0.60 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr3_-_20227619 0.51 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr16_-_67969888 0.49 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr11_+_34654011 0.47 ENST00000531794.1
ets homologous factor
chr14_-_85996332 0.47 ENST00000380722.1
RP11-497E19.1
chr5_-_135290705 0.45 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr14_+_21525981 0.43 ENST00000308227.2
ribonuclease, RNase A family, 8
chr6_-_44281043 0.42 ENST00000244571.4
alanyl-tRNA synthetase 2, mitochondrial
chr22_-_17073700 0.40 ENST00000359963.3
chaperonin containing TCP1, subunit 8 (theta)-like 2
chr4_-_100356291 0.38 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_1418154 0.38 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr10_+_114135004 0.38 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr13_-_41706864 0.37 ENST00000379485.1
ENST00000499385.2
kelch repeat and BTB (POZ) domain containing 6
chr10_+_114133773 0.37 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr7_+_138943265 0.35 ENST00000483726.1
ubinuclein 2
chr12_+_66217911 0.34 ENST00000403681.2
high mobility group AT-hook 2
chr2_+_234959323 0.33 ENST00000373368.1
ENST00000168148.3
secreted phosphoprotein 2, 24kDa
chr15_-_80263506 0.33 ENST00000335661.6
BCL2-related protein A1
chr13_-_33112823 0.33 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr9_+_470288 0.31 ENST00000382303.1
KN motif and ankyrin repeat domains 1
chr12_+_113376157 0.31 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr5_+_42756903 0.31 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr11_+_5372738 0.29 ENST00000380219.1
olfactory receptor, family 51, subfamily B, member 6
chr15_-_85197501 0.27 ENST00000434634.2
WD repeat domain 73
chr1_-_67142710 0.27 ENST00000502413.2
Uncharacterized protein
chr13_+_76378357 0.27 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr12_+_109785708 0.27 ENST00000310903.5
myosin IH
chr10_+_106113515 0.27 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chr6_-_29343068 0.27 ENST00000396806.3
olfactory receptor, family 12, subfamily D, member 3
chr2_+_74056066 0.26 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAM binding protein
chrX_+_38211777 0.26 ENST00000039007.4
ornithine carbamoyltransferase
chr9_-_25678856 0.26 ENST00000358022.3
tumor suppressor candidate 1
chr9_-_99180597 0.26 ENST00000375256.4
zinc finger protein 367
chrX_+_56259316 0.26 ENST00000468660.1
Kruppel-like factor 8
chr6_+_125524785 0.25 ENST00000392482.2
tumor protein D52-like 1
chr11_-_88796803 0.24 ENST00000418177.2
ENST00000455756.2
glutamate receptor, metabotropic 5
chr3_+_142838091 0.24 ENST00000309575.3
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr2_+_39005336 0.24 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr19_+_58341656 0.24 ENST00000442832.4
ENST00000594901.1
zinc finger protein 587B
chr18_+_51795774 0.24 ENST00000579534.1
ENST00000406285.3
ENST00000577612.1
ENST00000579434.1
ENST00000583136.1
polymerase (DNA directed) iota
chr12_-_54691668 0.24 ENST00000553198.1
nuclear factor, erythroid 2
chr19_-_14952689 0.24 ENST00000248058.1
olfactory receptor, family 7, subfamily A, member 10
chr15_+_71389281 0.23 ENST00000355327.3
thrombospondin, type I, domain containing 4
chr1_+_28052456 0.23 ENST00000373954.6
ENST00000419687.2
family with sequence similarity 76, member A
chr3_-_146187088 0.23 ENST00000497985.1
phospholipid scramblase 2
chr6_-_39902160 0.23 ENST00000340692.5
molybdenum cofactor synthesis 1
chr4_+_118955500 0.23 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr12_-_132628847 0.23 ENST00000397333.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr4_+_9172135 0.23 ENST00000512047.1
family with sequence similarity 90, member A26
chr14_+_96722539 0.23 ENST00000553356.1
bradykinin receptor B1
chr1_-_39339777 0.22 ENST00000397572.2
MYC binding protein
chr3_+_173116225 0.22 ENST00000457714.1
neuroligin 1
chr20_+_814377 0.22 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr13_-_28024681 0.22 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
mitochondrial translational initiation factor 3
chr1_+_1109272 0.22 ENST00000379290.1
ENST00000379289.1
tubulin tyrosine ligase-like family, member 10
chr22_+_23241661 0.22 ENST00000390322.2
immunoglobulin lambda joining 2
chr19_-_4540486 0.22 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr6_+_127898312 0.22 ENST00000329722.7
chromosome 6 open reading frame 58
chr11_-_506316 0.21 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr11_+_124543694 0.21 ENST00000227135.2
ENST00000532692.1
sperm autoantigenic protein 17
chr13_+_25875785 0.21 ENST00000381747.3
nucleoporin like 1
chr10_-_101380121 0.21 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chr11_+_111126707 0.21 ENST00000280325.4
chromosome 11 open reading frame 53
chr15_+_75074385 0.21 ENST00000220003.9
c-src tyrosine kinase
chr10_-_102046417 0.20 ENST00000370372.2
biogenesis of lysosomal organelles complex-1, subunit 2
chr3_+_155838337 0.20 ENST00000490337.1
ENST00000389636.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr17_+_55163075 0.20 ENST00000571629.1
ENST00000570423.1
ENST00000575186.1
ENST00000573085.1
ENST00000572814.1
A kinase (PRKA) anchor protein 1
chr2_-_55496344 0.20 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr11_+_17281900 0.20 ENST00000530527.1
nucleobindin 2
chr1_+_111888890 0.20 ENST00000369738.4
primary cilia formation
chr2_+_127413677 0.20 ENST00000356887.7
glycophorin C (Gerbich blood group)
chr1_-_145075847 0.20 ENST00000530740.1
ENST00000369359.4
phosphodiesterase 4D interacting protein
chr1_-_109203997 0.20 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr10_-_22292613 0.20 ENST00000376980.3
DnaJ (Hsp40) homolog, subfamily C, member 1
chr5_-_37371278 0.20 ENST00000231498.3
nucleoporin 155kDa
chr17_-_74533963 0.20 ENST00000293230.5
cytoglobin
chr10_-_95462265 0.20 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chrX_+_46940254 0.19 ENST00000336169.3
regucalcin
chr3_-_52804872 0.19 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NIMA-related kinase 4
chr1_-_117210290 0.19 ENST00000369483.1
ENST00000369486.3
immunoglobulin superfamily, member 3
chr9_+_125273081 0.19 ENST00000335302.5
olfactory receptor, family 1, subfamily J, member 2
chr7_-_32338917 0.19 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr3_+_122399444 0.19 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr10_-_102046098 0.19 ENST00000441611.1
biogenesis of lysosomal organelles complex-1, subunit 2
chr1_+_54569968 0.19 ENST00000391366.1
Uncharacterized protein
chr13_+_37581115 0.19 ENST00000481013.1
exosome component 8
chr16_-_20367584 0.19 ENST00000570689.1
uromodulin
chr7_-_102789629 0.19 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr1_-_150207017 0.19 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_-_155635583 0.18 ENST00000367166.4
transcription factor B1, mitochondrial
chr15_+_89182156 0.18 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr1_-_197115818 0.18 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr8_+_124084899 0.18 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr3_-_72149553 0.18 ENST00000468646.2
ENST00000464271.1
long intergenic non-protein coding RNA 877
chr16_+_11038345 0.18 ENST00000409790.1
C-type lectin domain family 16, member A
chr16_+_31483374 0.18 ENST00000394863.3
transforming growth factor beta 1 induced transcript 1
chr1_-_94344754 0.18 ENST00000436063.2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr9_+_96793076 0.17 ENST00000375360.3
protein tyrosine phosphatase domain containing 1
chr2_+_36923933 0.17 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
vitrin
chrX_-_153979315 0.17 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GRB2-associated binding protein 3
chr6_+_30614779 0.17 ENST00000293604.6
ENST00000376473.5
chromosome 6 open reading frame 136
chr16_-_5147743 0.17 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
family with sequence similarity 86, member A
chr22_-_45559540 0.17 ENST00000432502.1
CTA-217C2.1
chr2_+_234959376 0.17 ENST00000425558.1
secreted phosphoprotein 2, 24kDa
chr12_+_68042495 0.17 ENST00000344096.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr16_-_84220604 0.17 ENST00000567759.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr19_+_51273721 0.17 ENST00000270590.4
G protein-coupled receptor 32
chr6_-_39902185 0.16 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
molybdenum cofactor synthesis 1
chr19_+_44576296 0.16 ENST00000421176.3
zinc finger protein 284
chr5_+_178368186 0.16 ENST00000320129.3
ENST00000519564.1
zinc finger protein 454
chr6_+_132891461 0.16 ENST00000275198.1
trace amine associated receptor 6
chr14_+_39583427 0.16 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr20_-_62203808 0.16 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chr3_-_50336826 0.16 ENST00000443842.1
ENST00000354862.4
ENST00000443094.2
ENST00000415204.1
ENST00000336307.1
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr1_+_111889212 0.16 ENST00000369737.4
primary cilia formation
chr11_-_62439012 0.16 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
chromosome 11 open reading frame 48
chr1_+_234509413 0.16 ENST00000366613.1
ENST00000366612.1
cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
chr4_+_113558272 0.16 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr17_-_78428487 0.16 ENST00000562672.2
CTD-2526A2.2
chr9_+_99212403 0.16 ENST00000375251.3
ENST00000375249.4
hyaluronan binding protein 4
chr1_+_62417957 0.16 ENST00000307297.7
ENST00000543708.1
InaD-like (Drosophila)
chr3_+_184053703 0.16 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
family with sequence similarity 131, member A
chr1_+_55181490 0.16 ENST00000371281.3
tetratricopeptide repeat domain 4
chrX_-_33146477 0.15 ENST00000378677.2
dystrophin
chr2_+_65216462 0.15 ENST00000234256.3
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_+_14572070 0.15 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr22_-_45559642 0.15 ENST00000426282.2
CTA-217C2.1
chr6_+_110501621 0.15 ENST00000368930.1
ENST00000307731.1
cell division cycle 40
chr12_+_7053228 0.15 ENST00000540506.2
chromosome 12 open reading frame 57
chr17_-_46682321 0.15 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr2_+_220492287 0.15 ENST00000273063.6
ENST00000373762.3
solute carrier family 4 (anion exchanger), member 3
chr4_+_76871883 0.15 ENST00000599764.1
Uncharacterized protein
chr14_+_105267250 0.15 ENST00000342537.7
zinc finger and BTB domain containing 42
chr19_+_58193337 0.15 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551
chr9_+_131037623 0.15 ENST00000495313.1
ENST00000372898.2
SWI5 recombination repair homolog (yeast)
chr12_+_107168418 0.15 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr4_+_119606523 0.15 ENST00000388822.5
ENST00000506780.1
ENST00000508801.1
methyltransferase like 14
chr19_+_50529212 0.15 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
zinc finger protein 473
chr19_+_33182823 0.15 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr5_+_149109825 0.15 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_222763240 0.15 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr6_+_163148161 0.14 ENST00000337019.3
ENST00000366889.2
PARK2 co-regulated
chr2_+_220492116 0.14 ENST00000373760.2
solute carrier family 4 (anion exchanger), member 3
chr15_+_84115868 0.14 ENST00000427482.2
SH3-domain GRB2-like 3
chr7_-_91509986 0.14 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
mitochondrial transcription termination factor
chr9_+_95820966 0.14 ENST00000375472.3
ENST00000465709.1
sushi domain containing 3
chr9_-_6015607 0.14 ENST00000259569.5
RAN binding protein 6
chr21_-_37838739 0.14 ENST00000399139.1
claudin 14
chr15_+_84116106 0.14 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3
chr10_-_43133950 0.14 ENST00000359467.3
zinc finger protein 33B
chr10_-_22292675 0.14 ENST00000376946.1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr8_+_22224811 0.14 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr2_+_89986318 0.14 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr4_-_104119528 0.14 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr21_-_40720974 0.14 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr1_+_214776516 0.14 ENST00000366955.3
centromere protein F, 350/400kDa
chr15_+_75074410 0.14 ENST00000439220.2
c-src tyrosine kinase
chr11_+_62439126 0.14 ENST00000377953.3
chromosome 11 open reading frame 83
chr1_-_89458415 0.13 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr12_-_48419165 0.13 ENST00000547602.1
Uncharacterized protein
chr15_-_41624685 0.13 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr5_-_19988339 0.13 ENST00000382275.1
cadherin 18, type 2
chr15_-_57025759 0.13 ENST00000267807.7
zinc finger protein 280D
chr12_-_50419177 0.13 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr5_+_122181184 0.13 ENST00000513881.1
sorting nexin 24
chr12_-_42877408 0.13 ENST00000552240.1
prickle homolog 1 (Drosophila)
chr2_+_219110149 0.13 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_209131059 0.13 ENST00000422495.1
ENST00000452564.1
phosphoinositide kinase, FYVE finger containing
chr5_+_122181279 0.13 ENST00000395451.4
ENST00000506996.1
sorting nexin 24
chr1_+_93646238 0.13 ENST00000448243.1
ENST00000370276.1
coiled-coil domain containing 18
chr3_+_23847394 0.13 ENST00000306627.3
ubiquitin-conjugating enzyme E2E 1
chr16_+_50775971 0.13 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
cylindromatosis (turban tumor syndrome)
chr3_+_196669494 0.13 ENST00000602845.1
NCBP2 antisense RNA 2 (head to head)
chr10_-_129691195 0.13 ENST00000368671.3
clarin 3
chr9_-_74675521 0.13 ENST00000377024.3
chromosome 9 open reading frame 57
chr17_-_38574169 0.13 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr2_+_36923830 0.13 ENST00000379242.3
ENST00000389975.3
vitrin
chr15_+_39542867 0.13 ENST00000318578.3
ENST00000561223.1
chromosome 15 open reading frame 54
chr16_-_84220633 0.13 ENST00000566732.1
ENST00000561955.1
ENST00000564454.1
ENST00000341690.6
ENST00000541676.1
ENST00000570117.1
ENST00000564345.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr13_-_24463530 0.13 ENST00000382172.3
mitochondrial intermediate peptidase
chr10_-_71930222 0.13 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr15_+_89181974 0.13 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr19_-_52489923 0.12 ENST00000593596.1
ENST00000243644.4
ENST00000594929.1
ENST00000601430.1
zinc finger protein 350
chr3_+_62936098 0.12 ENST00000475886.1
ENST00000465684.1
ENST00000465262.1
ENST00000468072.1
long intergenic non-protein coding RNA 698
chr12_+_66218212 0.12 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
high mobility group AT-hook 2
chrX_+_100353153 0.12 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr15_+_45694523 0.12 ENST00000305560.6
spermatogenesis associated 5-like 1
chr10_-_115614127 0.12 ENST00000369305.1
DNA cross-link repair 1A
chr3_+_3168600 0.12 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
tRNA nucleotidyl transferase, CCA-adding, 1
chr7_-_138363824 0.12 ENST00000419765.3
SVOP-like
chr17_+_30469579 0.12 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr16_+_20817839 0.12 ENST00000348433.6
ENST00000568501.1
ENST00000566276.1
Putative RNA exonuclease NEF-sp
chr1_-_53163992 0.12 ENST00000371538.3
cytochrome c oxidase assembly factor 7
chr18_-_48351743 0.12 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
maestro
chr9_+_37485932 0.12 ENST00000377798.4
ENST00000442009.2
polymerase (RNA) I polypeptide E, 53kDa
chr15_+_69365265 0.12 ENST00000415504.1
long intergenic non-protein coding RNA 277
chr8_+_144120648 0.12 ENST00000395172.1
chromosome 8 open reading frame 31
chr19_+_44716678 0.12 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
zinc finger protein 227
chr9_-_35815013 0.12 ENST00000259667.5
histidine triad nucleotide binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.3 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.2 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.5 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0071029 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.1 GO:1905154 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:2000232 regulation of rRNA processing(GO:2000232)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.0 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.5 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0043813 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA