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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for INSM1

Z-value: 0.71

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Transcription factors associated with INSM1

Gene Symbol Gene ID Gene Info
INSM1
ENSG00000173404.3 INSM transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
INSM1hg19_v2_chr20_+_20348740_203487650.096.6e-01Click!

Activity profile of INSM1 motif

Sorted Z-values of INSM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_123691439 4.58 ENST00000540010.1
TRAF1
TNF receptor-associated factor 1
chr15_+_89182178 4.05 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 4.00 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 3.47 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_-_29595779 2.10 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_-_153573965 1.93 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr5_-_150466692 1.83 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr19_+_10197463 1.46 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr12_+_49372251 1.37 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr2_-_153573887 1.28 ENST00000493468.2
ENST00000545856.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_+_118307179 1.23 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A
chr1_+_65613340 1.15 ENST00000546702.1
AK4
adenylate kinase 4
chr19_+_10196781 0.96 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr10_+_91061712 0.88 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr19_+_10196981 0.88 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr1_+_65613217 0.84 ENST00000545314.1
AK4
adenylate kinase 4
chr11_-_65430554 0.74 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_-_120548779 0.74 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr1_-_205325850 0.71 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr19_+_35629702 0.71 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr1_+_160370344 0.68 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr11_-_65430251 0.67 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_35630022 0.66 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr2_+_152266604 0.66 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr10_+_35415851 0.61 ENST00000374726.3
CREM
cAMP responsive element modulator
chr14_-_51297197 0.59 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr17_+_46184911 0.59 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr15_-_51058005 0.58 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A
chrX_+_37430822 0.56 ENST00000378621.3
ENST00000378619.3
LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr12_+_53773944 0.56 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr14_-_104313824 0.53 ENST00000553739.1
ENST00000202556.9
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr12_-_51419924 0.53 ENST00000541174.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_153750622 0.53 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr12_-_51420108 0.52 ENST00000547198.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr15_-_70388943 0.51 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr3_+_185304059 0.50 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr2_+_152266392 0.50 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chr1_+_10490779 0.50 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr12_-_51420128 0.49 ENST00000262051.7
ENST00000547732.1
ENST00000262052.5
ENST00000546488.1
ENST00000550714.1
ENST00000548193.1
ENST00000547579.1
ENST00000546743.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr12_-_50101003 0.49 ENST00000550488.1
FMNL3
formin-like 3
chr14_-_51297837 0.46 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr22_+_38071615 0.45 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_-_73389854 0.43 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
GRB2
growth factor receptor-bound protein 2
chr11_-_57092381 0.42 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr17_-_1389419 0.39 ENST00000575158.1
MYO1C
myosin IC
chr12_-_76953453 0.38 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr17_-_73389737 0.38 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr2_+_153191706 0.36 ENST00000288670.9
FMNL2
formin-like 2
chr3_-_15374033 0.35 ENST00000253688.5
ENST00000383791.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr6_+_108881012 0.35 ENST00000343882.6
FOXO3
forkhead box O3
chr15_-_52263937 0.34 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr17_-_1389228 0.34 ENST00000438665.2
MYO1C
myosin IC
chr4_+_56815102 0.34 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr19_+_45394477 0.34 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr20_+_48807351 0.33 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_220863187 0.33 ENST00000294889.5
C1orf115
chromosome 1 open reading frame 115
chr14_-_85996332 0.33 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr17_+_27717415 0.32 ENST00000583121.1
ENST00000261716.3
TAOK1
TAO kinase 1
chr12_+_53645870 0.31 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr1_-_6321035 0.31 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr11_-_57417405 0.30 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr6_+_108882069 0.30 ENST00000406360.1
FOXO3
forkhead box O3
chr5_+_32174483 0.29 ENST00000606994.1
CTD-2186M15.3
CTD-2186M15.3
chr11_-_46142615 0.29 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr11_+_58346584 0.29 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr9_+_116263778 0.29 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr11_-_47400078 0.29 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chrX_+_16804544 0.29 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr1_-_36851489 0.28 ENST00000373130.3
ENST00000373132.3
STK40
serine/threonine kinase 40
chr1_-_1051455 0.28 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159
chromosome 1 open reading frame 159
chr11_-_47399942 0.28 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_-_39325431 0.28 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr19_+_42817450 0.28 ENST00000301204.3
TMEM145
transmembrane protein 145
chr6_-_9933500 0.27 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr15_+_45722727 0.27 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr9_+_116263639 0.27 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr1_-_1051736 0.27 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
C1orf159
chromosome 1 open reading frame 159
chr5_-_60140009 0.27 ENST00000505959.1
ELOVL7
ELOVL fatty acid elongase 7
chr4_+_26322409 0.27 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_73563735 0.27 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr11_+_32914579 0.26 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr5_-_60140089 0.26 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL7
ELOVL fatty acid elongase 7
chr1_-_36851475 0.26 ENST00000373129.3
STK40
serine/threonine kinase 40
chr7_-_128695147 0.25 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
TNPO3
transportin 3
chr6_+_31126291 0.24 ENST00000376257.3
ENST00000376255.4
TCF19
transcription factor 19
chr6_-_97345689 0.24 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr12_+_3000073 0.23 ENST00000397132.2
TULP3
tubby like protein 3
chr17_-_37382105 0.22 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr7_-_128694927 0.22 ENST00000471166.1
ENST00000265388.5
TNPO3
transportin 3
chr5_-_11904100 0.21 ENST00000359640.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr1_+_10490441 0.21 ENST00000470413.2
ENST00000309048.3
APITD1-CORT
APITD1
APITD1-CORT readthrough
apoptosis-inducing, TAF9-like domain 1
chr22_-_30695471 0.21 ENST00000434291.1
RP1-130H16.18
Uncharacterized protein
chr3_+_185303962 0.21 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr12_+_53774423 0.21 ENST00000426431.2
SP1
Sp1 transcription factor
chr11_-_46142948 0.21 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr2_-_27603582 0.21 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr9_-_98269699 0.20 ENST00000429896.2
PTCH1
patched 1
chrX_-_71525742 0.20 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr16_+_88704978 0.19 ENST00000244241.4
IL17C
interleukin 17C
chr17_+_19912640 0.19 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr5_-_11904152 0.19 ENST00000304623.8
ENST00000458100.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr12_-_76953513 0.19 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr9_+_115983808 0.19 ENST00000374210.6
ENST00000374212.4
SLC31A1
solute carrier family 31 (copper transporter), member 1
chr12_+_3000037 0.19 ENST00000544943.1
ENST00000448120.2
TULP3
tubby like protein 3
chr10_-_103603568 0.19 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr17_-_56606639 0.18 ENST00000579371.1
SEPT4
septin 4
chr12_-_54779511 0.18 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr11_-_47400062 0.18 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_-_236445251 0.18 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr17_-_56606664 0.18 ENST00000580844.1
SEPT4
septin 4
chr1_+_168148273 0.17 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr17_-_56606705 0.17 ENST00000317268.3
SEPT4
septin 4
chr22_+_37447771 0.17 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr2_+_208394794 0.17 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr7_+_100318423 0.17 ENST00000252723.2
EPO
erythropoietin
chr14_+_31343951 0.17 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
COCH
cochlin
chr7_-_105752651 0.16 ENST00000470347.1
ENST00000455385.2
SYPL1
synaptophysin-like 1
chr21_+_46066331 0.16 ENST00000334670.8
KRTAP10-11
keratin associated protein 10-11
chr17_+_42081914 0.16 ENST00000293404.3
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr11_-_40314652 0.16 ENST00000527150.1
LRRC4C
leucine rich repeat containing 4C
chr9_-_37034028 0.15 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr12_-_52887034 0.15 ENST00000330722.6
KRT6A
keratin 6A
chr7_-_91509986 0.15 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr19_-_49220084 0.15 ENST00000595591.1
ENST00000356751.4
ENST00000594582.1
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr17_+_52978156 0.15 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chr12_+_113860042 0.15 ENST00000403593.4
SDSL
serine dehydratase-like
chr12_+_113860160 0.15 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL
serine dehydratase-like
chr17_+_7211280 0.15 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chr7_-_105752971 0.15 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr10_+_88516396 0.15 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr20_+_44657845 0.14 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr7_+_114055052 0.14 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr9_+_140125385 0.13 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_+_49977466 0.13 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr14_+_76776957 0.13 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr12_-_6960407 0.13 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr19_+_55795493 0.13 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr3_+_35681081 0.12 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_-_151936865 0.12 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr17_-_36762095 0.12 ENST00000578925.1
ENST00000264659.7
SRCIN1
SRC kinase signaling inhibitor 1
chr9_+_140125209 0.11 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_+_48972265 0.11 ENST00000452733.2
CYTH2
cytohesin 2
chr20_-_30310797 0.11 ENST00000422920.1
BCL2L1
BCL2-like 1
chr20_+_35202909 0.11 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr16_+_67360712 0.10 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr17_+_34058639 0.10 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr6_+_155054459 0.10 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8
SR-related CTD-associated factor 8
chr2_-_73511559 0.10 ENST00000521871.1
FBXO41
F-box protein 41
chr15_+_90118685 0.10 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr2_-_25475120 0.10 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr19_+_19626531 0.10 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr5_+_178986693 0.10 ENST00000437570.2
ENST00000393438.2
RUFY1
RUN and FYVE domain containing 1
chr17_-_7297519 0.10 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_+_56814968 0.10 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr11_+_66610883 0.09 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr17_-_7297833 0.09 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr15_-_77924689 0.09 ENST00000355300.6
LINGO1
leucine rich repeat and Ig domain containing 1
chr11_-_64014379 0.09 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr13_+_47127293 0.09 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr9_-_136242956 0.09 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr1_-_99470368 0.08 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr8_-_103136481 0.08 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chr8_+_28174649 0.08 ENST00000301908.3
PNOC
prepronociceptin
chr5_-_32174369 0.08 ENST00000265070.6
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr15_+_90118723 0.08 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr11_-_118972575 0.08 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr9_+_136243117 0.08 ENST00000426926.2
ENST00000371957.3
C9orf96
chromosome 9 open reading frame 96
chr5_-_141030943 0.08 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr6_+_32938665 0.07 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr19_+_50887585 0.07 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1
polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_67525473 0.07 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr9_+_136243264 0.07 ENST00000371955.1
C9orf96
chromosome 9 open reading frame 96
chr7_+_86274145 0.07 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3
glutamate receptor, metabotropic 3
chr2_-_27435125 0.07 ENST00000414408.1
ENST00000310574.3
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr22_+_20105259 0.07 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1
RAN binding protein 1
chr1_-_99470558 0.07 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr1_-_37980344 0.07 ENST00000448519.2
ENST00000373075.2
ENST00000373073.4
ENST00000296214.5
MEAF6
MYST/Esa1-associated factor 6
chr18_-_51750948 0.06 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr14_+_106938440 0.06 ENST00000433371.1
ENST00000449670.1
ENST00000334298.3
LINC00221
long intergenic non-protein coding RNA 221
chr19_-_55881741 0.06 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11
interleukin 11
chr17_+_52978107 0.06 ENST00000445275.2
TOM1L1
target of myb1 (chicken)-like 1
chr6_+_32938692 0.06 ENST00000443797.2
BRD2
bromodomain containing 2
chr18_+_34409069 0.06 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr9_+_37650945 0.05 ENST00000377765.3
FRMPD1
FERM and PDZ domain containing 1
chr3_-_48601206 0.05 ENST00000273610.3
UCN2
urocortin 2
chr12_-_76953573 0.05 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8
oxysterol binding protein-like 8
chr17_-_47755338 0.05 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr9_-_127533519 0.05 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr1_+_44679113 0.05 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1
DNA methyltransferase 1 associated protein 1
chr8_+_99076509 0.04 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr15_+_27216297 0.04 ENST00000333743.6
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr17_-_46667628 0.04 ENST00000498678.1
HOXB3
homeobox B3
chr1_+_54411715 0.04 ENST00000371370.3
ENST00000371368.1
LRRC42
leucine rich repeat containing 42
chr6_-_38607673 0.03 ENST00000481247.1
BTBD9
BTB (POZ) domain containing 9
chr1_+_2398876 0.03 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr2_+_95963052 0.03 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr17_-_46667594 0.03 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3
homeobox B3
chr9_-_34637718 0.02 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr22_+_20104947 0.02 ENST00000402752.1
RANBP1
RAN binding protein 1
chr3_-_39195037 0.02 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of INSM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.8 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.5 1.4 GO:0061054 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.4 1.4 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.3 1.5 GO:0015692 lead ion transport(GO:0015692)
0.2 1.4 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.7 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 1.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) regulation of cellular response to drug(GO:2001038)
0.2 2.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 1.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 0.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.8 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 4.8 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 2.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0048372 tricuspid valve morphogenesis(GO:0003186) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 3.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0001711 endodermal cell fate commitment(GO:0001711) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 1.4 GO:0071159 NF-kappaB complex(GO:0071159)
0.3 1.5 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.7 GO:0045160 myosin I complex(GO:0045160)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0001940 male pronucleus(GO:0001940)
0.1 11.5 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 3.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 1.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 2.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 2.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 1.5 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 4.6 GO:0031996 thioesterase binding(GO:0031996)
0.2 1.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.4 GO:0016015 morphogen activity(GO:0016015)
0.1 0.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0030395 lactose binding(GO:0030395)
0.1 0.3 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 3.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.7 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 12.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation