Inflammatory response time course, HUVEC (Wada et al., 2009)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
IRF7 | hg19_v2_chr11_-_615942_615999 | 0.88 | 6.9e-09 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr10_+_91152303 Show fit | 19.02 |
ENST00000371804.3
|
interferon-induced protein with tetratricopeptide repeats 1 |
|
chr6_+_32821924 Show fit | 15.71 |
ENST00000374859.2
ENST00000453265.2 |
proteasome (prosome, macropain) subunit, beta type, 9 |
|
chr13_-_43566301 Show fit | 14.11 |
ENST00000398762.3
ENST00000313640.7 ENST00000313624.7 |
epithelial stromal interaction 1 (breast) |
|
chr4_-_76944621 Show fit | 12.95 |
ENST00000306602.1
|
chemokine (C-X-C motif) ligand 10 |
|
chr12_+_113344755 Show fit | 11.15 |
ENST00000550883.1
|
2'-5'-oligoadenylate synthetase 1, 40/46kDa |
|
chr6_-_29527702 Show fit | 10.65 |
ENST00000377050.4
|
ubiquitin D |
|
chr10_+_91092241 Show fit | 9.46 |
ENST00000371811.4
|
interferon-induced protein with tetratricopeptide repeats 3 |
|
chr16_-_67970990 Show fit | 8.20 |
ENST00000358514.4
|
proteasome (prosome, macropain) subunit, beta type, 10 |
|
chr12_+_113344582 Show fit | 8.10 |
ENST00000202917.5
ENST00000445409.2 ENST00000452357.2 |
2'-5'-oligoadenylate synthetase 1, 40/46kDa |
|
chr1_+_79086088 Show fit | 7.67 |
ENST00000370751.5
ENST00000342282.3 |
interferon-induced protein 44-like |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 38.1 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
0.2 | 20.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
6.3 | 19.0 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
1.9 | 18.7 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
1.4 | 17.9 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
4.7 | 14.2 | GO:0045062 | extrathymic T cell selection(GO:0045062) |
2.7 | 10.9 | GO:0046967 | cytosol to ER transport(GO:0046967) |
2.1 | 10.7 | GO:0070842 | aggresome assembly(GO:0070842) |
1.0 | 10.4 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.4 | 10.1 | GO:1900115 | extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 29.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.0 | 24.8 | GO:0005739 | mitochondrion(GO:0005739) |
0.1 | 16.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
1.8 | 12.8 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 12.5 | GO:0031965 | nuclear membrane(GO:0031965) |
0.2 | 11.2 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 11.0 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
1.7 | 10.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.5 | 9.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 7.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.6 | 40.1 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
1.0 | 30.0 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
3.7 | 18.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.4 | 17.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 16.1 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.1 | 15.2 | GO:0004386 | helicase activity(GO:0004386) |
1.6 | 12.8 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
0.1 | 12.2 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.5 | 10.7 | GO:0070628 | proteasome binding(GO:0070628) |
3.4 | 10.1 | GO:0042007 | interleukin-18 binding(GO:0042007) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 18.9 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
0.1 | 9.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.3 | 8.9 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
0.3 | 8.9 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 8.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.1 | 8.0 | PID AURORA A PATHWAY | Aurora A signaling |
0.1 | 7.7 | PID BCR 5PATHWAY | BCR signaling pathway |
0.0 | 6.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 5.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.2 | 5.7 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 74.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.6 | 49.4 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
0.3 | 17.1 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.4 | 12.1 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.3 | 10.0 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
0.2 | 8.7 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.2 | 7.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 6.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.1 | 6.1 | REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
0.3 | 5.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |