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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for IRF7

Z-value: 1.88

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615942_6159990.886.9e-09Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91152303 19.02 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr6_+_32821924 15.71 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr13_-_43566301 14.11 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
epithelial stromal interaction 1 (breast)
chr4_-_76944621 12.95 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr12_+_113344755 11.15 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_29527702 10.65 ENST00000377050.4
ubiquitin D
chr10_+_91092241 9.46 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr16_-_67970990 8.20 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_113344582 8.10 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_79086088 7.67 ENST00000370751.5
ENST00000342282.3
interferon-induced protein 44-like
chr12_+_113416191 7.08 ENST00000342315.4
ENST00000392583.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_-_150738261 7.07 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr1_+_79115503 6.65 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr3_+_122399444 6.61 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr6_-_32821599 6.38 ENST00000354258.4
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_91087651 6.37 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_+_19799327 6.18 ENST00000540292.1
neuron navigator 2
chr6_-_160147925 6.08 ENST00000535561.1
superoxide dismutase 2, mitochondrial
chr4_+_142557717 5.96 ENST00000320650.4
ENST00000296545.7
interleukin 15
chr9_+_5510492 5.94 ENST00000397745.2
programmed cell death 1 ligand 2
chr22_-_36556821 5.86 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr10_-_6019984 5.86 ENST00000525219.2
interleukin 15 receptor, alpha
chr9_+_5510558 5.82 ENST00000397747.3
programmed cell death 1 ligand 2
chr2_-_231084659 5.81 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110 nuclear body protein
chr4_-_76957214 5.74 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr2_-_7005785 5.70 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr2_-_231084820 5.70 ENST00000258382.5
ENST00000338556.3
SP110 nuclear body protein
chr17_-_40264692 5.66 ENST00000591220.1
ENST00000251642.3
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_+_69455855 5.62 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr17_-_20370847 5.58 ENST00000423676.3
ENST00000324290.5
lectin, galactoside-binding, soluble, 9B
chr12_+_113376157 5.51 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr6_-_32806506 5.50 ENST00000374897.2
ENST00000452392.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr4_+_142557771 5.32 ENST00000514653.1
interleukin 15
chr16_+_57023406 5.27 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLR family, CARD domain containing 5
chr2_-_231084617 5.19 ENST00000409815.2
SP110 nuclear body protein
chr2_+_7017796 5.04 ENST00000382040.3
radical S-adenosyl methionine domain containing 2
chr1_-_89531041 4.94 ENST00000370473.4
guanylate binding protein 1, interferon-inducible
chr15_-_80263506 4.92 ENST00000335661.6
BCL2-related protein A1
chr7_+_55177416 4.88 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr17_+_41158742 4.74 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr10_+_91174314 4.69 ENST00000371795.4
interferon-induced protein with tetratricopeptide repeats 5
chr6_+_26440700 4.63 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr11_-_4414880 4.49 ENST00000254436.7
ENST00000543625.1
tripartite motif containing 21
chr8_+_27632083 4.49 ENST00000519637.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_+_102271129 4.43 ENST00000258534.8
DNA-damage regulated autophagy modulator 1
chr11_-_57335280 4.36 ENST00000287156.4
ubiquitin-conjugating enzyme E2L 6
chr10_-_6019552 4.29 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr6_+_26402465 4.24 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chr8_+_54764346 4.21 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr17_+_6659153 4.19 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XIAP associated factor 1
chr22_+_18632666 4.11 ENST00000215794.7
ubiquitin specific peptidase 18
chr3_-_122283079 4.07 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr2_+_127413677 4.06 ENST00000356887.7
glycophorin C (Gerbich blood group)
chr2_+_127413704 4.02 ENST00000409836.3
glycophorin C (Gerbich blood group)
chr1_-_89488510 4.00 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr12_+_113344811 3.87 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_127413481 3.82 ENST00000259254.4
glycophorin C (Gerbich blood group)
chr11_+_71710973 3.79 ENST00000393707.4
interleukin 18 binding protein
chr7_-_92777606 3.69 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr1_+_101185290 3.59 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr11_+_71710648 3.58 ENST00000260049.5
interleukin 18 binding protein
chr21_+_43619796 3.49 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr22_+_36044411 3.45 ENST00000409652.4
apolipoprotein L, 6
chr2_-_202562774 3.43 ENST00000396886.3
ENST00000409143.1
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_165796753 3.34 ENST00000367879.4
uridine-cytidine kinase 2
chr6_+_32811885 3.33 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr15_+_90544532 3.33 ENST00000268154.4
zinc finger protein 710
chr14_-_24615805 3.30 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_-_24615523 3.29 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_+_94577074 3.28 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr11_+_20044096 3.19 ENST00000533917.1
neuron navigator 2
chr11_-_117748138 3.19 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr4_-_169401628 3.19 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr21_+_27011584 3.16 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
junctional adhesion molecule 2
chr10_+_6625605 3.15 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr19_+_10196781 3.12 ENST00000253110.11
chromosome 19 open reading frame 66
chr21_+_43933946 3.10 ENST00000352133.2
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr11_-_104905840 3.08 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr20_+_53092123 3.05 ENST00000262593.5
docking protein 5
chr11_-_615570 3.05 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr3_+_122283064 3.04 ENST00000296161.4
deltex 3-like (Drosophila)
chr4_-_169239921 3.03 ENST00000514995.1
ENST00000393743.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr4_+_142558078 2.94 ENST00000529613.1
interleukin 15
chr22_+_36649056 2.92 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
apolipoprotein L, 1
chr2_-_231989808 2.92 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_615942 2.90 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr18_+_61554932 2.87 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr5_+_96212185 2.82 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr13_+_50070077 2.81 ENST00000378319.3
ENST00000426879.1
PHD finger protein 11
chr6_-_11779174 2.77 ENST00000379413.2
androgen-dependent TFPI-regulating protein
chr15_+_71228826 2.76 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr11_+_71709938 2.73 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
interleukin 18 binding protein
chr2_-_37899323 2.72 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr11_+_35211429 2.71 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr10_-_6019455 2.70 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
interleukin 15 receptor, alpha
chr6_-_101329157 2.66 ENST00000369143.2
activating signal cointegrator 1 complex subunit 3
chr5_+_96211643 2.66 ENST00000437043.3
ENST00000510373.1
endoplasmic reticulum aminopeptidase 2
chr2_-_231090344 2.64 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr19_+_10196981 2.63 ENST00000591813.1
chromosome 19 open reading frame 66
chr9_-_100881466 2.58 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
tripartite motif containing 14
chr8_+_27632047 2.57 ENST00000397418.2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr18_+_32173276 2.56 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr7_-_83824169 2.55 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_948803 2.49 ENST00000379389.4
ISG15 ubiquitin-like modifier
chr1_-_111746966 2.46 ENST00000369752.5
DENN/MADD domain containing 2D
chr3_-_116163830 2.40 ENST00000333617.4
limbic system-associated membrane protein
chr2_-_202562716 2.40 ENST00000428900.2
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr9_-_32526184 2.39 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_+_29322437 2.32 ENST00000434693.2
RNA binding motif, single stranded interacting protein 3
chr3_-_122283100 2.26 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr3_+_29322803 2.25 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr12_+_113416265 2.24 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr10_+_24497704 2.22 ENST00000376456.4
ENST00000458595.1
KIAA1217
chr10_+_114169299 2.20 ENST00000369410.3
acyl-CoA synthetase long-chain family member 5
chr2_-_220252603 2.18 ENST00000322176.7
ENST00000273075.4
aspartyl aminopeptidase
chr12_+_113376249 2.17 ENST00000551007.1
ENST00000548514.1
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_47735918 2.16 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BCL2 binding component 3
chr6_-_154751629 2.15 ENST00000424998.1
CNKSR family member 3
chr1_+_110453203 2.11 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
colony stimulating factor 1 (macrophage)
chr1_-_12677714 2.11 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr13_-_33780133 2.08 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr3_+_23244780 2.05 ENST00000396703.1
ubiquitin-conjugating enzyme E2E 2
chr9_+_100174232 2.04 ENST00000355295.4
tudor domain containing 7
chr10_+_91061712 2.02 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr17_-_49124230 2.02 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr7_-_122339162 2.00 ENST00000340112.2
ring finger protein 133
chr12_-_51422017 2.00 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr1_+_144989309 1.99 ENST00000596396.1
Uncharacterized protein
chr9_+_100174344 1.99 ENST00000422139.2
tudor domain containing 7
chr6_-_36355513 1.98 ENST00000340181.4
ENST00000373737.4
ets variant 7
chr6_-_101329191 1.98 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr3_+_154797877 1.95 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr6_-_32811771 1.93 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr6_-_87804815 1.92 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr9_+_102668915 1.91 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
syntaxin 17
chr2_+_32853093 1.89 ENST00000448773.1
ENST00000317907.4
tetratricopeptide repeat domain 27
chr20_-_47894569 1.88 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
zinc finger, NFX1-type containing 1
chr8_-_23540402 1.86 ENST00000523261.1
ENST00000380871.4
NK3 homeobox 1
chr12_-_26278030 1.86 ENST00000242728.4
basic helix-loop-helix family, member e41
chr6_-_35888905 1.86 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr1_+_110453608 1.78 ENST00000369801.1
colony stimulating factor 1 (macrophage)
chr2_+_102721023 1.78 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr14_+_24605389 1.77 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_111506562 1.76 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr17_-_33864772 1.76 ENST00000361112.4
schlafen family member 12-like
chr1_+_113217345 1.74 ENST00000357443.2
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr6_+_26402517 1.73 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr6_+_26365443 1.73 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr3_-_195997410 1.73 ENST00000419333.1
phosphate cytidylyltransferase 1, choline, alpha
chr12_+_72058130 1.72 ENST00000547843.1
THAP domain containing, apoptosis associated protein 2
chr16_-_79634595 1.72 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr14_+_24605361 1.72 ENST00000206451.6
ENST00000559123.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_+_113217309 1.71 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr11_-_104972158 1.70 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr10_-_92681033 1.69 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr1_+_50569575 1.67 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr1_+_113217043 1.66 ENST00000413052.2
Mov10, Moloney leukemia virus 10, homolog (mouse)
chrX_+_49969405 1.64 ENST00000376042.1
cyclin B3
chr1_+_113217073 1.64 ENST00000369645.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr4_-_139163491 1.64 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_+_9431324 1.63 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr11_-_128392085 1.63 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr5_-_96143796 1.62 ENST00000296754.3
endoplasmic reticulum aminopeptidase 1
chr11_+_35211511 1.62 ENST00000524922.1
CD44 molecule (Indian blood group)
chr7_-_138794394 1.62 ENST00000242351.5
ENST00000471652.1
zinc finger CCCH-type, antiviral 1
chr3_+_29323043 1.62 ENST00000452462.1
ENST00000456853.1
RNA binding motif, single stranded interacting protein 3
chr2_-_190044480 1.61 ENST00000374866.3
collagen, type V, alpha 2
chr10_+_115439282 1.61 ENST00000369321.2
ENST00000345633.4
caspase 7, apoptosis-related cysteine peptidase
chr20_+_44746885 1.59 ENST00000372285.3
CD40 molecule, TNF receptor superfamily member 5
chr3_+_119316689 1.59 ENST00000273371.4
phospholipase A1 member A
chr3_+_29322933 1.57 ENST00000273139.9
ENST00000383766.2
RNA binding motif, single stranded interacting protein 3
chrX_-_71526741 1.57 ENST00000454225.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr10_+_115439699 1.57 ENST00000369315.1
caspase 7, apoptosis-related cysteine peptidase
chr5_-_58571935 1.57 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr12_-_58165870 1.56 ENST00000257848.7
methyltransferase like 1
chr3_+_187086120 1.55 ENST00000259030.2
receptor (chemosensory) transporter protein 4
chr2_+_42104692 1.55 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr22_-_36635684 1.53 ENST00000358502.5
apolipoprotein L, 2
chr6_+_116575329 1.53 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
dermatan sulfate epimerase
RP3-486I3.7
chr10_+_115439630 1.50 ENST00000369318.3
caspase 7, apoptosis-related cysteine peptidase
chr10_+_24498060 1.50 ENST00000376454.3
ENST00000376452.3
KIAA1217
chr1_-_149900122 1.49 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr2_-_152146385 1.45 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr8_-_145060593 1.45 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr3_+_119316721 1.45 ENST00000488919.1
ENST00000495992.1
phospholipase A1 member A
chr11_-_85397167 1.41 ENST00000316398.3
coiled-coil domain containing 89
chr20_+_388679 1.38 ENST00000356286.5
ENST00000475269.1
RanBP-type and C3HC4-type zinc finger containing 1
chr6_+_32811861 1.37 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr5_-_58882219 1.37 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chr8_+_50822344 1.36 ENST00000518864.1
syntrophin, gamma 1
chr9_+_74764278 1.36 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr17_+_41363854 1.36 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
transmembrane protein 106A
chrX_+_56259316 1.35 ENST00000468660.1
Kruppel-like factor 8
chr8_+_27629459 1.34 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_-_49463753 1.33 ENST00000301068.6
Ras homolog enriched in brain like 1
chr4_-_47983519 1.33 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr2_-_163175133 1.32 ENST00000421365.2
ENST00000263642.2
interferon induced with helicase C domain 1
chr12_-_43833515 1.31 ENST00000549670.1
ENST00000395541.2
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr5_-_59481406 1.30 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr12_+_69201923 1.30 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 19.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
4.7 14.2 GO:0045062 extrathymic T cell selection(GO:0045062)
2.7 10.9 GO:0046967 cytosol to ER transport(GO:0046967)
2.2 8.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.1 10.7 GO:0070842 aggresome assembly(GO:0070842)
1.9 5.7 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
1.9 18.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
1.5 6.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.4 8.4 GO:0034421 post-translational protein acetylation(GO:0034421)
1.4 17.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.4 6.9 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.3 5.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.2 4.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.2 6.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
1.2 5.9 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.2 9.4 GO:0021564 vagus nerve development(GO:0021564)
1.2 9.3 GO:0018377 protein myristoylation(GO:0018377)
1.1 4.5 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
1.0 10.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.0 5.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
1.0 4.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.9 7.6 GO:0070141 response to UV-A(GO:0070141)
0.9 5.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.9 3.5 GO:0009726 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.9 8.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.8 3.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.7 7.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 3.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.7 0.7 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.6 1.9 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.6 1.9 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.6 6.8 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.6 1.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.6 10.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 4.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.6 2.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.6 3.4 GO:0071105 response to interleukin-11(GO:0071105)
0.6 1.7 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.5 4.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 1.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.5 2.5 GO:0048880 sensory system development(GO:0048880)
0.5 1.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.5 3.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.5 0.9 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.5 4.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5 2.3 GO:0015692 lead ion transport(GO:0015692)
0.5 3.6 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 1.8 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.4 0.9 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.4 1.3 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.4 3.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.4 7.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.4 2.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.4 1.6 GO:0033590 response to cobalamin(GO:0033590)
0.4 4.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 2.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 1.9 GO:0016240 autophagosome docking(GO:0016240)
0.4 1.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.4 1.1 GO:0010645 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.4 1.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.4 38.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.4 10.1 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 2.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.3 4.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.3 1.5 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 1.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.3 3.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 0.8 GO:0007518 myoblast fate determination(GO:0007518)
0.3 7.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 1.3 GO:0019401 alditol biosynthetic process(GO:0019401)
0.3 1.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 20.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 4.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 1.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 1.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 2.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 2.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.2 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.2 1.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 0.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 1.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.9 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 2.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.9 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 1.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 4.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 2.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 3.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.5 GO:0071288 T-helper 1 cell lineage commitment(GO:0002296) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 2.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.8 GO:0006116 NADH oxidation(GO:0006116)
0.1 6.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 3.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 2.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.8 GO:2000252 diet induced thermogenesis(GO:0002024) negative regulation of feeding behavior(GO:2000252)
0.1 3.3 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 0.3 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.1 1.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 1.0 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 0.6 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 1.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.1 0.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 2.9 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 2.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.9 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.7 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.1 1.8 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.6 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 3.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 3.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 6.8 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 8.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.6 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562) vestibular reflex(GO:0060005)
0.0 0.6 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 9.5 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0046549 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1903975 regulation of glial cell migration(GO:1903975)
0.0 2.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 2.3 GO:0006400 tRNA modification(GO:0006400)
0.0 2.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.6 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:1903760 regulation of potassium ion import(GO:1903286) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.8 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:1904073 trophectodermal cell proliferation(GO:0001834) negative regulation of smooth muscle cell apoptotic process(GO:0034392) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.5 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.0 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.5 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 1.3 GO:0031929 TOR signaling(GO:0031929)
0.0 0.2 GO:0007628 adult walking behavior(GO:0007628)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 29.2 GO:1990111 spermatoproteasome complex(GO:1990111)
1.8 12.8 GO:0042825 TAP complex(GO:0042825)
1.7 10.1 GO:0008537 proteasome activator complex(GO:0008537)
1.6 4.9 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.2 3.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.1 6.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.0 7.1 GO:0036021 endolysosome lumen(GO:0036021)
0.8 4.8 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.7 3.4 GO:0071797 LUBAC complex(GO:0071797)
0.6 4.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 1.8 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.6 2.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.5 1.6 GO:0005588 collagen type V trimer(GO:0005588)
0.5 9.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 2.3 GO:0070826 paraferritin complex(GO:0070826)
0.4 1.3 GO:0019034 viral replication complex(GO:0019034)
0.4 1.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.4 5.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 7.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 3.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 4.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.9 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 4.0 GO:0033391 chromatoid body(GO:0033391)
0.2 1.9 GO:0042587 glycogen granule(GO:0042587)
0.2 1.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 1.7 GO:0097255 R2TP complex(GO:0097255)
0.2 1.5 GO:0005579 membrane attack complex(GO:0005579)
0.2 11.2 GO:0016235 aggresome(GO:0016235)
0.2 0.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 0.5 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 1.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 11.0 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 0.7 GO:0097422 tubular endosome(GO:0097422)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 1.6 GO:0032059 bleb(GO:0032059)
0.1 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 4.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0036020 endolysosome membrane(GO:0036020)
0.1 16.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 7.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 2.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 6.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 1.9 GO:0005643 nuclear pore(GO:0005643)
0.0 4.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 1.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0030686 90S preribosome(GO:0030686)
0.0 1.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 12.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541) nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 2.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.9 GO:0042383 sarcolemma(GO:0042383)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 5.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 24.8 GO:0005739 mitochondrion(GO:0005739)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
3.6 40.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
3.4 10.1 GO:0042007 interleukin-18 binding(GO:0042007)
1.6 12.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
1.4 5.7 GO:0009041 uridylate kinase activity(GO:0009041)
1.3 10.1 GO:0061133 endopeptidase activator activity(GO:0061133)
1.2 3.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.1 8.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.0 4.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 30.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 6.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.8 6.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.7 2.9 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.7 6.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 1.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 10.7 GO:0070628 proteasome binding(GO:0070628)
0.5 1.5 GO:0017130 poly(C) RNA binding(GO:0017130)
0.5 2.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.5 1.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 2.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 3.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 3.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.4 1.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.4 3.8 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.4 17.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.4 1.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 3.3 GO:0004849 uridine kinase activity(GO:0004849)
0.4 7.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.9 GO:0004882 androgen receptor activity(GO:0004882)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 1.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 3.7 GO:0050693 LBD domain binding(GO:0050693)
0.2 2.9 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 2.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 7.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 4.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 4.9