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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for IRX2

Z-value: 0.46

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.8 iroquois homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg19_v2_chr5_-_2751762_27517840.301.5e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_80263506 0.61 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr5_+_147258266 0.60 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr3_-_127441406 0.55 ENST00000487473.1
ENST00000484451.1
MGLL
monoglyceride lipase
chrX_+_9431324 0.41 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr1_+_10292308 0.37 ENST00000377081.1
KIF1B
kinesin family member 1B
chr11_+_103907308 0.33 ENST00000302259.3
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr10_-_61122220 0.32 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr4_-_153332886 0.31 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr6_-_53013620 0.31 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr5_+_54320078 0.31 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr1_+_74701062 0.25 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chrX_-_49042778 0.24 ENST00000538114.1
ENST00000376310.3
ENST00000376317.3
ENST00000417014.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr17_-_2614927 0.24 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chrX_-_21676442 0.23 ENST00000379499.2
KLHL34
kelch-like family member 34
chr5_-_35048047 0.23 ENST00000231420.6
AGXT2
alanine--glyoxylate aminotransferase 2
chr4_+_57371509 0.22 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr11_+_33037652 0.22 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr3_+_97887544 0.22 ENST00000356526.2
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr14_+_29236269 0.20 ENST00000313071.4
FOXG1
forkhead box G1
chr1_-_207095324 0.20 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr8_+_40018977 0.19 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr19_-_35719609 0.19 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr12_-_16758304 0.19 ENST00000320122.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_157811588 0.19 ENST00000368174.4
CD5L
CD5 molecule-like
chr4_-_168155417 0.19 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chrX_+_30261847 0.19 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr12_-_16758059 0.18 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_+_62648336 0.18 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_+_16308711 0.18 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr6_-_31620455 0.17 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
BAG6
BCL2-associated athanogene 6
chr21_-_31538971 0.17 ENST00000286808.3
CLDN17
claudin 17
chr18_-_33702078 0.17 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr5_-_94417314 0.17 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr4_-_70505358 0.17 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr16_+_21244986 0.16 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr3_-_151102529 0.16 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr12_+_32655110 0.16 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_+_66218903 0.16 ENST00000393577.3
HMGA2
high mobility group AT-hook 2
chr6_+_88117683 0.15 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr5_-_94417339 0.15 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr6_-_31620403 0.15 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
BAG6
BCL2-associated athanogene 6
chr2_+_159651821 0.15 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr4_-_80247162 0.15 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr6_+_37897735 0.15 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr11_+_111126707 0.15 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr1_-_238649319 0.15 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr6_-_9933500 0.14 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr1_+_31883048 0.14 ENST00000536859.1
SERINC2
serine incorporator 2
chrX_+_150869023 0.14 ENST00000448324.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr10_+_46997926 0.14 ENST00000374314.4
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr21_+_43823983 0.13 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr4_-_14889791 0.13 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr1_+_113009163 0.13 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr1_-_207095212 0.13 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr3_-_11645925 0.12 ENST00000413604.1
VGLL4
vestigial like 4 (Drosophila)
chr8_+_24151553 0.12 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr19_+_3762645 0.12 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr1_+_113010056 0.12 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr4_+_80748640 0.12 ENST00000514836.1
PCAT4
prostate cancer associated transcript 4 (non-protein coding)
chr18_+_5748793 0.12 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1
chr1_-_111506562 0.12 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr10_-_100027943 0.12 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr14_+_75536280 0.11 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr16_+_68678892 0.11 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr3_-_112565703 0.11 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr6_-_159466136 0.11 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr8_+_30244580 0.11 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chrX_-_100129128 0.11 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr11_-_59383617 0.10 ENST00000263847.1
OSBP
oxysterol binding protein
chrX_+_19373700 0.10 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr1_-_173793458 0.10 ENST00000356198.2
CENPL
centromere protein L
chr14_+_50999744 0.10 ENST00000441560.2
ATL1
atlastin GTPase 1
chr15_-_20193370 0.10 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr7_-_107770794 0.10 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
LAMB4
laminin, beta 4
chr14_+_75536335 0.10 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr19_-_38720354 0.10 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chr12_+_66218598 0.10 ENST00000541363.1
HMGA2
high mobility group AT-hook 2
chr12_+_40787194 0.09 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr5_-_180242534 0.09 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr6_-_27841289 0.09 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr11_-_118305921 0.09 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr12_+_54402790 0.09 ENST00000040584.4
HOXC8
homeobox C8
chr5_+_167913450 0.09 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr3_-_122102065 0.09 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chrX_+_155227371 0.09 ENST00000369423.2
ENST00000540897.1
IL9R
interleukin 9 receptor
chr1_-_156698181 0.09 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chrX_+_155227246 0.08 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr16_-_4401258 0.08 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr14_-_106312010 0.08 ENST00000390556.2
IGHD
immunoglobulin heavy constant delta
chr5_-_142814241 0.08 ENST00000504572.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_27925019 0.08 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr3_-_167371740 0.08 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr3_-_186262166 0.08 ENST00000307944.5
CRYGS
crystallin, gamma S
chr20_+_56136136 0.08 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_+_29138654 0.08 ENST00000234961.2
OPRD1
opioid receptor, delta 1
chr17_+_900342 0.08 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr6_-_159466042 0.07 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr4_+_189060573 0.07 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr8_-_82359662 0.07 ENST00000519260.1
ENST00000256103.2
PMP2
peripheral myelin protein 2
chr1_-_190446759 0.07 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr11_-_76381029 0.07 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr1_+_215747118 0.07 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr19_-_40336969 0.06 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
FBL
fibrillarin
chr12_+_4714145 0.06 ENST00000545342.1
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chrX_-_24045303 0.06 ENST00000328046.8
KLHL15
kelch-like family member 15
chr19_+_18669809 0.06 ENST00000602094.1
KXD1
KxDL motif containing 1
chr10_+_102672712 0.06 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr2_+_242577097 0.06 ENST00000419606.1
ENST00000474739.2
ENST00000396411.3
ENST00000425239.1
ENST00000400771.3
ENST00000430617.2
ATG4B
autophagy related 4B, cysteine peptidase
chr7_+_95115210 0.06 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr3_+_108541545 0.06 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_+_128399965 0.06 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr18_+_55018044 0.06 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr3_+_132843652 0.06 ENST00000508711.1
TMEM108
transmembrane protein 108
chr1_+_166958346 0.06 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr2_+_168675182 0.05 ENST00000305861.1
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chrX_-_100129320 0.05 ENST00000372966.3
NOX1
NADPH oxidase 1
chr17_-_3337135 0.05 ENST00000248384.1
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr22_-_36013368 0.05 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr7_-_14880892 0.05 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr6_+_24775153 0.05 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr2_-_109605663 0.05 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr3_+_46616017 0.05 ENST00000542931.1
TDGF1
teratocarcinoma-derived growth factor 1
chr1_+_166958497 0.05 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr10_-_28270795 0.05 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr12_-_91505608 0.05 ENST00000266718.4
LUM
lumican
chr19_-_29704448 0.05 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr16_-_5083917 0.04 ENST00000312251.3
ENST00000381955.3
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr2_+_196313239 0.04 ENST00000413290.1
AC064834.1
AC064834.1
chr10_+_134150835 0.04 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr2_-_98280383 0.04 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr4_+_88896819 0.04 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr1_-_151148442 0.04 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr10_+_1095416 0.04 ENST00000358220.1
WDR37
WD repeat domain 37
chr14_-_65289812 0.04 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB
spectrin, beta, erythrocytic
chr2_-_233877912 0.04 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr10_-_4285923 0.04 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr19_-_38720294 0.04 ENST00000412732.1
ENST00000456296.1
DPF1
D4, zinc and double PHD fingers family 1
chr8_+_94767072 0.04 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67
transmembrane protein 67
chr6_-_136847099 0.03 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr4_-_109541539 0.03 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr1_-_173572181 0.03 ENST00000536496.1
ENST00000367714.3
SLC9C2
solute carrier family 9, member C2 (putative)
chr6_+_46661575 0.03 ENST00000450697.1
TDRD6
tudor domain containing 6
chr3_-_194072019 0.03 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr17_-_7761256 0.03 ENST00000575208.1
LSMD1
LSM domain containing 1
chrX_-_132095419 0.03 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr6_-_136847610 0.03 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr18_+_50278430 0.03 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC
deleted in colorectal carcinoma
chr20_+_43849941 0.03 ENST00000372769.3
SEMG2
semenogelin II
chr1_+_67673297 0.03 ENST00000425614.1
ENST00000395227.1
IL23R
interleukin 23 receptor
chr8_+_67405794 0.03 ENST00000522977.1
ENST00000480005.1
C8orf46
chromosome 8 open reading frame 46
chr4_+_114214125 0.03 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr16_+_69373323 0.03 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr17_-_26127525 0.02 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chr4_+_158141843 0.02 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr7_-_33140498 0.02 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr4_+_158141899 0.02 ENST00000264426.9
ENST00000506284.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr11_+_59824127 0.02 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr1_+_110527308 0.02 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr7_+_150065278 0.02 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr19_-_42463418 0.02 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1
Rab acceptor 1 (prenylated)
chr16_+_58426296 0.02 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chr2_+_27851863 0.02 ENST00000264718.3
ENST00000610189.1
GPN1
GPN-loop GTPase 1
chr14_+_52327109 0.02 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_151148492 0.02 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr6_+_30908747 0.02 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr4_+_159131630 0.02 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr12_+_66218212 0.02 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr19_+_13134772 0.01 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr16_+_81272287 0.01 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr7_-_105332084 0.01 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr2_-_70520539 0.01 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chrX_-_70331298 0.01 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr5_-_138210977 0.01 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr7_+_80275953 0.01 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr2_-_166060571 0.01 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr14_+_23790655 0.01 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr1_+_152691998 0.01 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr2_-_89160770 0.01 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr11_+_98891797 0.01 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5
contactin 5
chr3_+_148457585 0.01 ENST00000402260.1
AGTR1
angiotensin II receptor, type 1
chr1_+_204839959 0.01 ENST00000404076.1
NFASC
neurofascin
chr4_+_187187337 0.01 ENST00000492972.2
F11
coagulation factor XI
chr18_+_32455201 0.00 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr12_+_128399917 0.00 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chrX_-_138790348 0.00 ENST00000414978.1
ENST00000519895.1
MCF2
MCF.2 cell line derived transforming sequence
chr2_+_171034646 0.00 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr1_+_166958504 0.00 ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904647 response to rotenone(GO:1904647)
0.1 0.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.3 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.3 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression