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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for IRX3

Z-value: 0.78

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Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.11 iroquois homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_543207150.242.4e-01Click!

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_127541194 1.96 ENST00000453507.2
monoglyceride lipase
chr5_+_54320078 1.66 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr12_-_71182695 1.42 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr12_+_117348742 1.40 ENST00000309909.5
ENST00000455858.2
F-box and WD repeat domain containing 8
chr10_+_118305435 1.36 ENST00000369221.2
pancreatic lipase
chr5_+_35856951 1.32 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr4_-_70080449 1.24 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_-_76957214 1.22 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr1_+_87012753 1.21 ENST00000370563.3
chloride channel accessory 4
chr3_+_122399444 1.07 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr11_+_35201826 1.04 ENST00000531873.1
CD44 molecule (Indian blood group)
chr7_-_92777606 1.03 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr3_-_127441406 1.02 ENST00000487473.1
ENST00000484451.1
monoglyceride lipase
chr2_-_89545079 1.01 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr1_-_89488510 1.00 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr3_-_123512688 0.98 ENST00000475616.1
myosin light chain kinase
chr11_+_35211429 0.94 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr1_-_201438282 0.86 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr4_+_74606223 0.82 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr17_-_34207295 0.82 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr13_+_97928395 0.82 ENST00000445661.2
muscleblind-like splicing regulator 2
chr22_-_36556821 0.80 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr10_-_90712520 0.80 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr15_+_67420441 0.78 ENST00000558894.1
SMAD family member 3
chr21_-_43528548 0.76 ENST00000329015.2
chromosome 21 open reading frame 128
chr10_+_91092241 0.75 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_89975669 0.74 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr11_+_20044600 0.73 ENST00000311043.8
neuron navigator 2
chr15_+_72947079 0.70 ENST00000421285.3
golgin A6 family, member B
chr5_-_59481406 0.65 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr5_+_135385202 0.65 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr2_-_216878305 0.62 ENST00000263268.6
melanoregulin
chr3_-_122283079 0.61 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr13_-_88323218 0.61 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr17_+_25958174 0.59 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr17_+_18380051 0.58 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
lectin, galactoside-binding, soluble, 9C
chr3_+_122283064 0.58 ENST00000296161.4
deltex 3-like (Drosophila)
chr8_-_125577940 0.56 ENST00000519168.1
ENST00000395508.2
metastasis suppressor 1
chr5_+_175490540 0.56 ENST00000515817.1
family with sequence similarity 153, member B
chr2_-_207629997 0.55 ENST00000454776.2
malate dehydrogenase 1B, NAD (soluble)
chr5_+_147443534 0.55 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
serine peptidase inhibitor, Kazal type 5
chr5_-_13944652 0.54 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr19_+_20959098 0.54 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr7_-_41742697 0.53 ENST00000242208.4
inhibin, beta A
chr2_-_16804320 0.53 ENST00000355549.2
family with sequence similarity 49, member A
chr4_-_95264008 0.51 ENST00000295256.5
hematopoietic prostaglandin D synthase
chr7_+_55086703 0.51 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
epidermal growth factor receptor
chr7_-_122339162 0.50 ENST00000340112.2
ring finger protein 133
chr1_-_197115818 0.50 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_-_231989808 0.49 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr5_+_159848807 0.49 ENST00000352433.5
pituitary tumor-transforming 1
chr1_+_87458692 0.49 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr5_-_177207634 0.48 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr6_-_35765088 0.48 ENST00000259938.2
colipase, pancreatic
chr4_+_122722466 0.48 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr1_+_196857144 0.47 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr2_-_207630033 0.47 ENST00000449792.1
malate dehydrogenase 1B, NAD (soluble)
chr4_-_104119528 0.46 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr5_+_110427983 0.46 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr2_-_231090344 0.46 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr15_+_75575176 0.45 ENST00000434739.3
golgin A6 family, member D
chr3_+_173116225 0.45 ENST00000457714.1
neuroligin 1
chrX_-_15353629 0.45 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
phosphatidylinositol glycan anchor biosynthesis, class A
chr8_+_95558771 0.44 ENST00000391679.1
HCG2009141; PRO2397; Uncharacterized protein
chr7_+_20687017 0.44 ENST00000258738.6
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr18_+_45778672 0.44 ENST00000600091.1
HCG1818186; Uncharacterized protein
chr18_+_9885961 0.44 ENST00000306084.6
thioredoxin domain containing 2 (spermatozoa)
chr1_+_31883048 0.44 ENST00000536859.1
serine incorporator 2
chr17_+_56232494 0.44 ENST00000268912.5
olfactory receptor, family 4, subfamily D, member 1
chr22_+_30821732 0.43 ENST00000355143.4
mitochondrial fission process 1
chr7_-_101212244 0.43 ENST00000451953.1
ENST00000434537.1
ENST00000437900.1
long intergenic non-protein coding RNA 1007
chr14_+_73563735 0.43 ENST00000532192.1
RNA binding motif protein 25
chr3_+_171561127 0.42 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr4_-_70826725 0.42 ENST00000353151.3
casein beta
chrX_+_15767971 0.42 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr11_-_104905840 0.42 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr3_-_27498235 0.41 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr8_+_12803176 0.40 ENST00000524591.2
KIAA1456
chr12_-_91574142 0.40 ENST00000547937.1
decorin
chr5_+_159848854 0.39 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr22_+_37309662 0.38 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr3_+_173302222 0.38 ENST00000361589.4
neuroligin 1
chr11_-_57177586 0.38 ENST00000529411.1
Uncharacterized protein
chr11_+_111783450 0.38 ENST00000537382.1
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr4_+_175839506 0.37 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM metallopeptidase domain 29
chr16_+_19421803 0.37 ENST00000541464.1
transmembrane channel-like 5
chr1_+_158985457 0.37 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr21_-_34186006 0.36 ENST00000490358.1
chromosome 21 open reading frame 62
chr3_-_122283100 0.36 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr12_-_91573132 0.36 ENST00000550563.1
ENST00000546370.1
decorin
chr8_+_9009202 0.36 ENST00000518496.1
Uncharacterized protein
chr12_-_87232644 0.36 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr19_-_10491234 0.35 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
tyrosine kinase 2
chr15_-_89089860 0.35 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
de-etiolated homolog 1 (Arabidopsis)
chr3_-_50378235 0.35 ENST00000357043.2
Ras association (RalGDS/AF-6) domain family member 1
chr11_-_102496063 0.34 ENST00000260228.2
matrix metallopeptidase 20
chr7_+_123241908 0.34 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chr2_+_233527443 0.34 ENST00000410095.1
EF-hand domain family, member D1
chr2_+_133874577 0.33 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr12_-_10251603 0.33 ENST00000457018.2
C-type lectin domain family 1, member A
chr10_+_118350468 0.33 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
pancreatic lipase-related protein 1
chr8_+_9009296 0.33 ENST00000521718.1
Uncharacterized protein
chr3_-_191000172 0.33 ENST00000427544.2
urotensin 2B
chr5_+_68485433 0.32 ENST00000502689.1
centromere protein H
chr17_-_29641084 0.32 ENST00000544462.1
ecotropic viral integration site 2B
chr10_+_118350522 0.32 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
pancreatic lipase-related protein 1
chr3_+_142838091 0.32 ENST00000309575.3
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr19_+_38779778 0.32 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4
chr4_-_34041504 0.31 ENST00000512581.1
ENST00000505018.1
RP11-79E3.3
chr2_+_143635222 0.31 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr1_-_89591749 0.31 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr3_+_52245458 0.31 ENST00000459884.1
aminolevulinate, delta-, synthase 1
chr12_-_6451235 0.31 ENST00000440083.2
ENST00000162749.2
tumor necrosis factor receptor superfamily, member 1A
chr11_-_111782696 0.31 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr1_-_52870104 0.30 ENST00000371568.3
origin recognition complex, subunit 1
chr8_+_132952112 0.30 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr2_-_166060552 0.30 ENST00000283254.7
ENST00000453007.1
sodium channel, voltage-gated, type III, alpha subunit
chr5_-_45696253 0.30 ENST00000303230.4
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr14_-_105487381 0.30 ENST00000392590.3
ENST00000336219.3
cell division cycle associated 4
chr11_+_12308447 0.30 ENST00000256186.2
MICAL C-terminal like
chr4_-_83769996 0.29 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr2_+_161993465 0.29 ENST00000457476.1
TRAF family member-associated NFKB activator
chr17_-_29648761 0.29 ENST00000247270.3
ENST00000462804.2
ecotropic viral integration site 2A
chr11_-_89653576 0.29 ENST00000420869.1
tripartite motif containing 49D1
chr13_-_20080080 0.29 ENST00000400103.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr21_-_34185989 0.29 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr2_-_69098566 0.29 ENST00000295379.1
bone morphogenetic protein 10
chr16_+_56969284 0.29 ENST00000568358.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_-_134585221 0.29 ENST00000372190.3
ENST00000427994.1
Rap guanine nucleotide exchange factor (GEF) 1
chr5_+_162887556 0.28 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr2_-_151428735 0.28 ENST00000441356.1
AC104777.2
chr8_+_27631903 0.28 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_+_127661942 0.28 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr4_-_170924888 0.28 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr10_+_94352956 0.28 ENST00000260731.3
kinesin family member 11
chr19_+_38085731 0.28 ENST00000589117.1
zinc finger protein 540
chr22_+_24030321 0.27 ENST00000401461.1
ral guanine nucleotide dissociation stimulator-like 4
chr7_+_44240520 0.27 ENST00000496112.1
ENST00000223369.2
YKT6 v-SNARE homolog (S. cerevisiae)
chr15_+_69706585 0.27 ENST00000559279.1
ENST00000395392.2
kinesin family member 23
chr15_-_56757329 0.27 ENST00000260453.3
meiosis-specific nuclear structural 1
chr2_+_101591314 0.27 ENST00000450763.1
neuronal PAS domain protein 2
chr1_-_53608249 0.27 ENST00000371494.4
solute carrier family 1 (glutamate transporter), member 7
chr12_+_8309630 0.27 ENST00000396570.3
zinc finger protein 705A
chr5_+_169010638 0.27 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr9_+_100174232 0.26 ENST00000355295.4
tudor domain containing 7
chr1_-_9714644 0.26 ENST00000377320.3
chromosome 1 open reading frame 200
chr16_+_21689835 0.26 ENST00000286149.4
ENST00000388958.3
otoancorin
chr6_+_22569784 0.26 ENST00000510882.2
hepatoma derived growth factor-like 1
chr5_-_95297678 0.26 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr6_+_29407083 0.26 ENST00000444197.2
olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr19_+_41281282 0.26 ENST00000263369.3
melanoma inhibitory activity
chrX_+_30261847 0.26 ENST00000378981.3
ENST00000397550.1
melanoma antigen family B, 1
chr12_-_21487829 0.25 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
solute carrier organic anion transporter family, member 1A2
chr18_+_32173276 0.25 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr10_-_127371675 0.25 ENST00000532135.1
ENST00000526819.1
ENST00000368821.3
testis expressed 36
chr3_-_157251383 0.25 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr5_+_32788945 0.25 ENST00000326958.1
AC026703.1
chr15_+_52155001 0.25 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr8_-_134072593 0.25 ENST00000427060.2
Src-like-adaptor
chr6_-_27835357 0.25 ENST00000331442.3
histone cluster 1, H1b
chr7_+_144052381 0.25 ENST00000498580.1
ENST00000056217.5
Rho guanine nucleotide exchange factor (GEF) 5
chr4_-_103997862 0.24 ENST00000394785.3
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr20_-_18477862 0.24 ENST00000337227.4
retinoblastoma binding protein 9
chr4_-_47983519 0.24 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr5_+_59783540 0.24 ENST00000515734.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr2_+_9983483 0.24 ENST00000263663.5
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr3_-_72897545 0.24 ENST00000325599.8
SHQ1, H/ACA ribonucleoprotein assembly factor
chr5_+_81601166 0.24 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr6_+_126277842 0.24 ENST00000229633.5
histidine triad nucleotide binding protein 3
chr20_+_34824355 0.23 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2 splicing factor homolog (S. cerevisiae)
chr8_-_101962777 0.23 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr19_-_48059113 0.23 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
zinc finger protein 541
chr8_+_22225041 0.23 ENST00000289952.5
ENST00000524285.1
solute carrier family 39 (zinc transporter), member 14
chr2_+_113885138 0.23 ENST00000409930.3
interleukin 1 receptor antagonist
chr2_+_106679690 0.23 ENST00000409944.1
chromosome 2 open reading frame 40
chr20_+_57875758 0.23 ENST00000395654.3
endothelin 3
chr1_-_47407097 0.23 ENST00000457840.2
cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_-_27384737 0.23 ENST00000317945.6
coiled-coil domain containing 34
chr14_+_52164820 0.23 ENST00000554167.1
FERM domain containing 6
chr1_+_44584522 0.23 ENST00000372299.3
Kruppel-like factor 17
chr20_-_1373682 0.22 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr17_+_35732955 0.22 ENST00000300618.4
chromosome 17 open reading frame 78
chr14_+_96722152 0.22 ENST00000216629.6
bradykinin receptor B1
chr16_+_1578674 0.22 ENST00000253934.5
transmembrane protein 204
chr4_+_169842707 0.22 ENST00000503290.1
palladin, cytoskeletal associated protein
chr6_-_32784687 0.22 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr3_-_46068969 0.22 ENST00000542109.1
ENST00000395946.2
chemokine (C motif) receptor 1
chr20_+_43990576 0.22 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr17_+_34639793 0.22 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
chemokine (C-C motif) ligand 4-like 2
chr16_+_78056412 0.22 ENST00000299642.4
ENST00000575655.1
C-type lectin domain family 3, member A
chr6_+_63921399 0.22 ENST00000356170.3
FK506 binding protein 1C
chr5_-_131879205 0.22 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chrX_+_49969405 0.22 ENST00000376042.1
cyclin B3
chr12_+_75874460 0.21 ENST00000266659.3
GLI pathogenesis-related 1
chr13_-_95248511 0.21 ENST00000261296.5
TDP-glucose 4,6-dehydratase
chr1_-_182369751 0.21 ENST00000367565.1
transmembrane epididymal protein 1
chr6_-_26199471 0.21 ENST00000341023.1
histone cluster 1, H2ad
chr9_+_96846740 0.21 ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chrX_-_83757399 0.21 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
highly divergent homeobox
chr10_+_52094298 0.21 ENST00000595931.1
HCG1745369; PRO3073; Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 0.8 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2 2.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.6 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 0.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 1.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 0.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.5 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 1.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 1.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.6 GO:0030035 microspike assembly(GO:0030035)
0.1 0.7 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.5 GO:0048749 compound eye development(GO:0048749)
0.1 0.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.2 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.2 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 0.3 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.6 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) negative regulation of defense response to bacterium(GO:1900425)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 1.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.1 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 1.4 GO:0060716 spongiotrophoblast layer development(GO:0060712) labyrinthine layer blood vessel development(GO:0060716)
0.1 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.5 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0002586 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.0 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.5 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.2 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.8 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.6 GO:0032402 melanosome transport(GO:0032402)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0044241 lipid digestion(GO:0044241)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.0 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.0 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.4 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 3.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 2.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 2.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins