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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for IRX5

Z-value: 0.47

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Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
IRX5
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_549647890.213.1e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_22379753 0.64 ENST00000397121.2
ZNF676
zinc finger protein 676
chr13_+_97928395 0.55 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr10_-_115904361 0.47 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr17_-_29641084 0.43 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr2_+_133874577 0.38 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr2_+_173686303 0.35 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_96722539 0.32 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr3_-_9994021 0.31 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr4_+_141264597 0.31 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr14_+_22386325 0.30 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chrY_-_6742068 0.29 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr1_-_85870177 0.28 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr15_-_80634104 0.28 ENST00000561432.1
ENST00000558913.1
ENST00000558578.1
LINC00927
long intergenic non-protein coding RNA 927
chr4_-_104119528 0.27 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr1_+_97188188 0.26 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr4_+_41361616 0.25 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_196857144 0.24 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr4_+_169842707 0.23 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr8_-_12668962 0.23 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr4_-_22444733 0.23 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr6_-_26216872 0.22 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr7_+_13141097 0.22 ENST00000411542.1
AC011288.2
AC011288.2
chr8_-_17555164 0.21 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr5_-_177207634 0.20 ENST00000513554.1
ENST00000440605.3
FAM153A
family with sequence similarity 153, member A
chr12_-_127174806 0.20 ENST00000545853.1
ENST00000537478.1
RP11-407A16.3
RP11-407A16.3
chr1_-_244006528 0.20 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr5_+_147443534 0.20 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr3_-_27498235 0.20 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr5_-_156390230 0.19 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr15_-_64665911 0.18 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr2_+_191792376 0.17 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr6_-_52705641 0.17 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr5_+_175490540 0.17 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr1_-_112106578 0.16 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr13_-_46716969 0.16 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_213020991 0.16 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chr1_-_152086556 0.16 ENST00000368804.1
TCHH
trichohyalin
chr20_+_43990576 0.16 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr14_-_23623577 0.16 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr8_-_101962777 0.15 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr12_-_52867569 0.15 ENST00000252250.6
KRT6C
keratin 6C
chr16_+_21689835 0.15 ENST00000286149.4
ENST00000388958.3
OTOA
otoancorin
chr15_+_41057818 0.15 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr20_+_10199468 0.15 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr13_-_20080080 0.15 ENST00000400103.2
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr3_+_180586536 0.14 ENST00000465551.1
FXR1
fragile X mental retardation, autosomal homolog 1
chr14_+_73563735 0.14 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr11_+_60048004 0.14 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr21_+_38792602 0.14 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr2_+_160590469 0.14 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chrX_+_36065053 0.14 ENST00000313548.4
CHDC2
calponin homology domain containing 2
chr9_+_117904097 0.13 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr18_+_616672 0.13 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr14_-_23624511 0.13 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr6_+_140175987 0.13 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr5_+_128300810 0.13 ENST00000262462.4
SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr1_+_196743943 0.12 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr1_+_158969752 0.12 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr12_+_101869096 0.12 ENST00000551346.1
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chrX_-_15333736 0.12 ENST00000380470.3
ASB11
ankyrin repeat and SOCS box containing 11
chr1_+_196743912 0.12 ENST00000367425.4
CFHR3
complement factor H-related 3
chr16_+_56969284 0.12 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_-_36001108 0.11 ENST00000333811.4
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chrX_-_15353629 0.11 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr12_+_8309630 0.11 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr13_-_88323218 0.11 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr3_-_52713729 0.11 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr17_+_58018269 0.11 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr7_-_92777606 0.11 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr20_+_54933971 0.10 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr14_-_106967788 0.10 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr4_+_75480629 0.10 ENST00000380846.3
AREGB
amphiregulin B
chr12_-_100486668 0.10 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr4_-_38784592 0.10 ENST00000502321.1
TLR10
toll-like receptor 10
chr22_-_24096562 0.10 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr2_-_88427568 0.10 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr21_-_48024986 0.10 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr12_+_32655048 0.10 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr16_-_58585513 0.10 ENST00000245138.4
ENST00000567285.1
CNOT1
CCR4-NOT transcription complex, subunit 1
chr8_+_71520812 0.10 ENST00000499227.2
RP11-382J12.1
Uncharacterized protein
chr6_-_117747015 0.09 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr4_-_143481822 0.09 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_-_62190793 0.09 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr5_+_169010638 0.09 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr7_-_138348969 0.09 ENST00000436657.1
SVOPL
SVOP-like
chr14_+_51706886 0.09 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr8_+_22225041 0.09 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr11_+_22688150 0.09 ENST00000454584.2
GAS2
growth arrest-specific 2
chr8_-_108510224 0.09 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr4_+_76995855 0.09 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chr10_+_118187379 0.08 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr8_-_16035454 0.08 ENST00000355282.2
MSR1
macrophage scavenger receptor 1
chr11_-_89653576 0.08 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr12_-_11036844 0.08 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr4_+_75310851 0.08 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr1_+_53308398 0.08 ENST00000371528.1
ZYG11A
zyg-11 family member A, cell cycle regulator
chr1_+_53480598 0.08 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr9_-_125667618 0.08 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr6_+_29364416 0.07 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr19_-_52227221 0.07 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr12_-_21757774 0.07 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr4_+_159131630 0.07 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr4_+_130017268 0.07 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr7_-_86595190 0.07 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr14_-_95624227 0.07 ENST00000526495.1
DICER1
dicer 1, ribonuclease type III
chr1_+_152975488 0.07 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr1_-_89488510 0.07 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr11_+_31531291 0.07 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr17_-_29641104 0.07 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr19_-_40596828 0.07 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
ZNF780A
zinc finger protein 780A
chr11_-_22647350 0.07 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr2_-_183106641 0.07 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_+_68053359 0.07 ENST00000478136.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr12_-_4553385 0.06 ENST00000543077.1
FGF6
fibroblast growth factor 6
chr1_+_15668240 0.06 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr11_+_59807748 0.06 ENST00000278855.2
ENST00000532905.1
PLAC1L
oocyte secreted protein 2
chr2_+_113829895 0.06 ENST00000393197.2
IL1F10
interleukin 1 family, member 10 (theta)
chrX_-_120071012 0.06 ENST00000457020.2
CT47A11
cancer/testis antigen family 47, member A11
chr15_+_54901540 0.06 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr3_+_12392971 0.06 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr13_-_41768654 0.06 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr16_+_87636474 0.06 ENST00000284262.2
JPH3
junctophilin 3
chr12_-_102224704 0.06 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr7_-_112430427 0.06 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr3_-_149470229 0.06 ENST00000473414.1
COMMD2
COMM domain containing 2
chr4_-_186392898 0.06 ENST00000510617.1
ENST00000307588.3
CCDC110
coiled-coil domain containing 110
chr19_+_50691437 0.06 ENST00000598205.1
MYH14
myosin, heavy chain 14, non-muscle
chr3_+_53528659 0.06 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_-_120066151 0.06 ENST00000419982.2
ENST00000416816.1
CT47A12
cancer/testis antigen family 47, member A12
chr17_+_3379284 0.06 ENST00000263080.2
ASPA
aspartoacylase
chr8_+_9009296 0.06 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr9_+_42704004 0.05 ENST00000457288.1
CBWD7
COBW domain containing 7
chr18_+_6729725 0.05 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr16_-_90128733 0.05 ENST00000325921.6
PRDM7
PR domain containing 7
chr22_+_18721427 0.05 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr4_+_80584903 0.05 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr12_-_25102252 0.05 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr8_+_27631903 0.05 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr10_+_118350522 0.05 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr3_-_20053741 0.05 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr8_+_67976593 0.05 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr6_+_42584847 0.05 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_112106556 0.05 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr6_-_111804905 0.05 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_+_71833550 0.05 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr11_+_114310237 0.05 ENST00000539119.1
REXO2
RNA exonuclease 2
chr8_-_16050288 0.05 ENST00000350896.3
MSR1
macrophage scavenger receptor 1
chr1_-_241683001 0.05 ENST00000366560.3
FH
fumarate hydratase
chrX_+_15767971 0.05 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr1_-_114355083 0.05 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr14_-_74769759 0.04 ENST00000356924.4
ABCD4
ATP-binding cassette, sub-family D (ALD), member 4
chr10_+_118350468 0.04 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr2_-_40657397 0.04 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_116502527 0.04 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr4_+_185973026 0.04 ENST00000506338.1
ENST00000509017.1
RP11-386B13.3
RP11-386B13.3
chr4_-_103998439 0.04 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr19_-_23456996 0.04 ENST00000594653.1
RP11-15H20.7
RP11-15H20.7
chr6_+_146920116 0.04 ENST00000367493.3
ADGB
androglobin
chr1_+_63989004 0.04 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr6_-_111804393 0.04 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr6_+_146920097 0.04 ENST00000397944.3
ENST00000522242.1
ADGB
androglobin
chr17_+_35732955 0.04 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr15_+_49170083 0.04 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr16_+_19535235 0.04 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr14_-_23877474 0.04 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr12_-_10282681 0.04 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr3_-_81792780 0.04 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr14_-_23876801 0.04 ENST00000356287.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chrX_-_52258669 0.04 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr4_+_113739244 0.04 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr15_+_25200108 0.04 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr3_-_139199565 0.04 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr14_+_50291993 0.04 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr11_-_35547572 0.04 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr14_-_106845789 0.03 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr3_+_35681728 0.03 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr18_+_33709834 0.03 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
ELP2
elongator acetyltransferase complex subunit 2
chr12_-_10282836 0.03 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr1_+_109256067 0.03 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr6_-_52774464 0.03 ENST00000370968.1
ENST00000211122.3
GSTA3
glutathione S-transferase alpha 3
chr7_+_77469439 0.03 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr3_+_155838337 0.03 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr11_+_114310102 0.03 ENST00000265881.5
REXO2
RNA exonuclease 2
chrX_+_52513455 0.03 ENST00000446098.1
XAGE1C
X antigen family, member 1C
chr12_-_120315074 0.03 ENST00000261833.7
ENST00000392521.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr9_-_100707116 0.03 ENST00000259456.3
HEMGN
hemogen
chr4_+_56212270 0.03 ENST00000264228.4
SRD5A3
steroid 5 alpha-reductase 3
chr7_-_92855762 0.03 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr2_+_201173667 0.03 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr10_+_95326416 0.03 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
FFAR4
free fatty acid receptor 4
chrX_+_52240504 0.03 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr18_-_32924372 0.03 ENST00000261332.6
ENST00000399061.3
ZNF24
zinc finger protein 24
chr14_-_21737551 0.03 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr16_+_19535133 0.03 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr12_-_10282742 0.03 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr6_+_149887377 0.03 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr17_-_3301704 0.03 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr6_-_128239685 0.03 ENST00000368250.1
THEMIS
thymocyte selection associated
chr9_-_4666421 0.03 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr19_-_44952635 0.03 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.0 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling