Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for ISL2

Z-value: 0.36

Motif logo

Transcription factors associated with ISL2

Gene Symbol Gene ID Gene Info
ENSG00000159556.5 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL2hg19_v2_chr15_+_76629064_76629073-0.058.1e-01Click!

Activity profile of ISL2 motif

Sorted Z-values of ISL2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58212487 0.55 ENST00000549994.1
advillin
chr2_+_86669118 0.52 ENST00000427678.1
ENST00000542128.1
lysine (K)-specific demethylase 3A
chr4_+_128702969 0.50 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr12_+_131438443 0.49 ENST00000261654.5
G protein-coupled receptor 133
chr7_+_13141097 0.47 ENST00000411542.1
AC011288.2
chr4_+_95128748 0.36 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr21_-_31859755 0.36 ENST00000334055.3
keratin associated protein 19-2
chr2_+_105050794 0.35 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr3_-_141747950 0.34 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_115670804 0.33 ENST00000320239.7
transcription factor EC
chr7_-_115670792 0.33 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr11_+_5410607 0.29 ENST00000328611.3
olfactory receptor, family 51, subfamily M, member 1
chr13_+_78315295 0.28 ENST00000351546.3
SLAIN motif family, member 1
chr14_+_38677123 0.27 ENST00000267377.2
somatostatin receptor 1
chr11_-_28129656 0.27 ENST00000263181.6
kinesin family member 18A
chr1_+_149871135 0.27 ENST00000369152.5
bolA family member 1
chr11_+_28129795 0.26 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr17_-_3496171 0.25 ENST00000399756.4
transient receptor potential cation channel, subfamily V, member 1
chr3_-_191000172 0.24 ENST00000427544.2
urotensin 2B
chr14_-_67878917 0.23 ENST00000216446.4
pleckstrin 2
chr6_-_111804905 0.21 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr11_+_86085778 0.18 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
coiled-coil domain containing 81
chr12_+_64798095 0.17 ENST00000332707.5
exportin, tRNA
chrX_-_32173579 0.16 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
dystrophin
chr4_-_138453606 0.16 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr2_-_231860596 0.15 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
SPATA3 antisense RNA 1 (head to head)
chr1_-_190446759 0.15 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr5_+_32788945 0.14 ENST00000326958.1
AC026703.1
chr12_-_95945246 0.14 ENST00000258499.3
ubiquitin specific peptidase 44
chr10_-_128359074 0.14 ENST00000544758.1
chromosome 10 open reading frame 90
chr14_+_102276132 0.14 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_+_95128996 0.14 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_+_169013666 0.13 ENST00000359299.3
annexin A10
chr12_-_118628350 0.13 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr14_+_45605157 0.13 ENST00000542564.2
Fanconi anemia, complementation group M
chr6_-_24358264 0.13 ENST00000378454.3
doublecortin domain containing 2
chr10_-_5046042 0.13 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr6_+_31105426 0.13 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr11_-_124190184 0.13 ENST00000357438.2
olfactory receptor, family 8, subfamily D, member 2
chr9_-_99540328 0.13 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr6_+_130339710 0.12 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr17_-_10372875 0.12 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr17_+_4710391 0.11 ENST00000263088.6
ENST00000572940.1
phospholipase D2
chr18_-_64271316 0.11 ENST00000540086.1
ENST00000580157.1
cadherin 19, type 2
chr2_-_10587897 0.11 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chrX_+_65384182 0.10 ENST00000441993.2
ENST00000419594.1
hephaestin
chr17_-_4938712 0.10 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr1_-_232651312 0.10 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr8_+_62747349 0.10 ENST00000517953.1
ENST00000520097.1
ENST00000519766.1
RP11-705O24.1
chr6_+_151561085 0.10 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr17_-_7307358 0.10 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_+_4402659 0.09 ENST00000301280.5
ENST00000585854.1
chromatin assembly factor 1, subunit A (p150)
chr2_+_234668894 0.09 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr5_+_68860949 0.09 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr1_-_223853348 0.09 ENST00000366872.5
calpain 8
chrM_+_9207 0.09 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr21_+_39644395 0.08 ENST00000398934.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr15_-_42500351 0.08 ENST00000348544.4
ENST00000318006.5
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr1_-_93257951 0.08 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
ecotropic viral integration site 5
chr4_+_88532028 0.08 ENST00000282478.7
dentin sialophosphoprotein
chr18_+_61575200 0.08 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr5_-_130500922 0.08 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
histidine triad nucleotide binding protein 1
chr5_+_40909354 0.08 ENST00000313164.9
complement component 7
chr6_-_155776966 0.08 ENST00000159060.2
NADPH oxidase 3
chrX_-_15332665 0.08 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr2_+_32502952 0.08 ENST00000238831.4
Yip1 domain family, member 4
chr16_+_53133070 0.08 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr7_-_45151272 0.08 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
transforming growth factor beta regulator 4
chr21_+_39644305 0.08 ENST00000398930.1
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_-_77225135 0.07 ENST00000458128.1
phosphoglycerate mutase family member 4
chr1_+_234765057 0.07 ENST00000429269.1
long intergenic non-protein coding RNA 184
chr16_-_3350614 0.07 ENST00000268674.2
tigger transposable element derived 7
chr9_-_21482312 0.06 ENST00000448696.3
interferon, epsilon
chrX_-_119077695 0.06 ENST00000371410.3
NFKB activating protein
chr1_-_12946025 0.06 ENST00000235349.5
PRAME family member 4
chrX_+_65382433 0.06 ENST00000374727.3
hephaestin
chr1_-_228613026 0.06 ENST00000366696.1
histone cluster 3, H3
chr1_-_13390765 0.06 ENST00000357367.2
PRAME family member 8
chr10_+_63422695 0.06 ENST00000330194.2
ENST00000389639.3
chromosome 10 open reading frame 107
chr4_-_138453559 0.06 ENST00000511115.1
protocadherin 18
chr6_+_64345698 0.06 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHD finger protein 3
chr5_+_40841276 0.06 ENST00000254691.5
caspase recruitment domain family, member 6
chr6_+_29555683 0.06 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr9_-_100854838 0.05 ENST00000538344.1
tripartite motif containing 14
chr14_-_74025625 0.05 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEAT repeat containing 4
chr10_-_95242044 0.05 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr18_-_64271363 0.05 ENST00000262150.2
cadherin 19, type 2
chr10_-_50396407 0.05 ENST00000374153.2
ENST00000374151.3
chromosome 10 open reading frame 128
chr1_+_171227069 0.05 ENST00000354841.4
flavin containing monooxygenase 1
chr1_+_13421176 0.05 ENST00000376152.1
PRAME family member 9
chr6_-_152639479 0.05 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr3_-_193096600 0.05 ENST00000446087.1
ENST00000342358.4
ATPase type 13A5
chr12_+_26164645 0.05 ENST00000542004.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr11_+_71544246 0.05 ENST00000328698.1
defensin, beta 108B
chr15_-_72563585 0.05 ENST00000287196.9
ENST00000260376.7
poly (ADP-ribose) polymerase family, member 6
chr8_-_121457608 0.05 ENST00000306185.3
mitochondrial ribosomal protein L13
chr3_+_172468472 0.04 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr21_+_15588499 0.04 ENST00000400577.3
RNA binding motif protein 11
chr17_-_64225508 0.04 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr3_-_20053741 0.04 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr19_-_36001113 0.04 ENST00000434389.1
dermokine
chr14_-_53258314 0.04 ENST00000216410.3
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr4_+_113568207 0.04 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr6_+_26440700 0.04 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr1_-_168464875 0.04 ENST00000422253.1
RP5-968D22.3
chr2_-_87248975 0.04 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr8_-_30706608 0.04 ENST00000256246.2
testis expressed 15
chr1_+_99127225 0.04 ENST00000370189.5
ENST00000529992.1
sorting nexin 7
chr13_+_24144509 0.03 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr17_-_10325261 0.03 ENST00000403437.2
myosin, heavy chain 8, skeletal muscle, perinatal
chr3_+_172468505 0.03 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr11_-_5323226 0.03 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chrX_+_108779004 0.03 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr10_-_95241951 0.03 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr2_-_209010874 0.03 ENST00000260988.4
crystallin, gamma B
chr15_-_83378638 0.03 ENST00000261722.3
adaptor-related protein complex 3, beta 2 subunit
chr21_-_31864275 0.03 ENST00000334063.4
keratin associated protein 19-3
chr3_+_169629354 0.03 ENST00000428432.2
ENST00000335556.3
sterile alpha motif domain containing 7
chr12_-_54689532 0.03 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr21_-_30445886 0.03 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr8_-_125577940 0.03 ENST00000519168.1
ENST00000395508.2
metastasis suppressor 1
chr4_+_15471489 0.03 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
coiled-coil and C2 domain containing 2A
chr2_-_217560248 0.03 ENST00000233813.4
insulin-like growth factor binding protein 5
chr1_+_63063152 0.02 ENST00000371129.3
angiopoietin-like 3
chr2_-_217559517 0.02 ENST00000449583.1
insulin-like growth factor binding protein 5
chr19_-_51920952 0.02 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr12_-_10282836 0.02 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chrX_+_102840408 0.02 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
transcription elongation factor A (SII)-like 4
chr10_-_27529486 0.02 ENST00000375888.1
acyl-CoA binding domain containing 5
chr2_+_113825547 0.02 ENST00000341010.2
ENST00000337569.3
interleukin 1 family, member 10 (theta)
chr12_+_122356488 0.02 ENST00000397454.2
WD repeat domain 66
chr4_-_69111401 0.02 ENST00000332644.5
transmembrane protease, serine 11B
chr1_+_149871171 0.02 ENST00000369150.1
bolA family member 1
chr8_+_92261516 0.02 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr13_+_49551020 0.02 ENST00000541916.1
fibronectin type III domain containing 3A
chr15_+_79166065 0.02 ENST00000559690.1
ENST00000559158.1
mortality factor 4 like 1
chr6_+_161123270 0.02 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr11_+_12132117 0.01 ENST00000256194.4
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr19_+_29456034 0.01 ENST00000589921.1
long intergenic non-protein coding RNA 906
chr11_-_92931098 0.01 ENST00000326402.4
solute carrier family 36 (proton/amino acid symporter), member 4
chr14_-_90798418 0.01 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr12_-_10282681 0.01 ENST00000533022.1
C-type lectin domain family 7, member A
chr2_+_234826016 0.01 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr7_+_141811539 0.01 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr11_-_5255861 0.01 ENST00000380299.3
hemoglobin, delta
chr18_-_3845321 0.01 ENST00000539435.1
ENST00000400147.2
discs, large (Drosophila) homolog-associated protein 1
chr2_-_159237472 0.01 ENST00000409187.1
coiled-coil domain containing 148
chr12_-_10282742 0.01 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr13_-_45768841 0.01 ENST00000379108.1
potassium channel tetramerization domain containing 4
chr5_+_140201183 0.01 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
protocadherin alpha 5
chr7_-_16844611 0.01 ENST00000401412.1
ENST00000419304.2
anterior gradient 2
chr1_-_178840157 0.00 ENST00000367629.1
ENST00000234816.2
angiopoietin-like 1
chr3_-_20227619 0.00 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr3_-_157221380 0.00 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr2_+_88047606 0.00 ENST00000359481.4
plasminogen-like B2
chr14_+_22670455 0.00 ENST00000390460.1
T cell receptor alpha variable 26-2
chr2_+_74685413 0.00 ENST00000233615.2
WW domain binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)