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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for JDP2

Z-value: 0.91

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Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
JDP2
ENSG00000140044.8 Jun dimerization protein 2

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_89182178 13.12 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 12.93 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 11.38 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_+_152214098 6.64 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr21_+_26934165 6.45 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr4_+_74606223 6.01 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr1_-_153521597 5.57 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr11_-_102668879 5.50 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_153521714 5.04 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr7_+_55177416 4.76 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr16_+_57662138 3.42 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 3.40 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr1_+_183155373 3.11 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr8_+_86157699 3.11 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr5_+_35856951 3.06 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr10_+_104155450 2.61 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_122085469 2.30 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr2_-_175712270 2.29 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr17_+_74381343 2.04 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_-_2950642 1.97 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr11_+_122526383 1.82 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr18_+_21693306 1.80 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr18_+_55888767 1.78 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_-_28257080 1.77 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_-_95007193 1.76 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr7_+_28725585 1.69 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr1_-_209824643 1.54 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr4_+_86525299 1.31 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr6_+_151042224 1.21 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_+_213224572 1.20 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr11_-_133715394 1.17 ENST00000299140.3
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr21_-_36421535 1.13 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr21_-_36421626 1.08 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr3_-_195997410 1.06 ENST00000419333.1
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr7_+_134528635 1.05 ENST00000445569.2
CALD1
caldesmon 1
chr22_+_39916558 1.04 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr1_+_156084461 0.99 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr17_+_79650962 0.97 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_+_179247759 0.89 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr3_+_48507621 0.88 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr6_+_106534192 0.86 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr9_+_138453595 0.85 ENST00000479141.1
ENST00000371766.2
ENST00000277508.5
ENST00000433563.1
PAEP
progestagen-associated endometrial protein
chr6_-_84140757 0.85 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr22_+_20861858 0.85 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr1_-_111148241 0.82 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr14_+_103800513 0.80 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr3_-_191000172 0.79 ENST00000427544.2
UTS2B
urotensin 2B
chr9_-_123638633 0.79 ENST00000456291.1
PHF19
PHD finger protein 19
chr2_+_69201705 0.77 ENST00000377938.2
GKN1
gastrokine 1
chr2_+_74757050 0.77 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr12_+_75760714 0.77 ENST00000547144.1
GLIPR1L1
GLI pathogenesis-related 1 like 1
chr10_-_120514720 0.77 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr3_+_48507210 0.77 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr1_+_152881014 0.77 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr9_-_123639304 0.75 ENST00000436309.1
PHF19
PHD finger protein 19
chr6_+_45296048 0.75 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chrX_-_48901012 0.67 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr17_-_47287928 0.67 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_+_48128194 0.66 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr18_-_74839891 0.64 ENST00000581878.1
MBP
myelin basic protein
chr7_+_48128316 0.63 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr4_+_169013666 0.63 ENST00000359299.3
ANXA10
annexin A10
chr11_+_5009424 0.59 ENST00000300762.1
MMP26
matrix metallopeptidase 26
chr1_-_203198790 0.58 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr16_+_30211181 0.56 ENST00000395138.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr17_-_38911580 0.56 ENST00000312150.4
KRT25
keratin 25
chr17_-_39296739 0.52 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr17_-_33760269 0.51 ENST00000452764.3
SLFN12
schlafen family member 12
chr1_+_156096336 0.50 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr17_+_28256874 0.49 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chrX_+_41193407 0.48 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr5_-_149492904 0.48 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr17_+_30771279 0.45 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr15_+_22892663 0.43 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr16_-_31161380 0.43 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr10_-_4285923 0.43 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr20_+_30946106 0.42 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr3_+_183903811 0.42 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr12_-_71182695 0.42 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr17_+_4853442 0.41 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr5_+_72143988 0.41 ENST00000506351.2
TNPO1
transportin 1
chr2_-_180610767 0.40 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr12_-_131200810 0.39 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chrX_+_153770421 0.39 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr6_+_10521574 0.38 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr7_-_155604967 0.38 ENST00000297261.2
SHH
sonic hedgehog
chr1_-_67142710 0.36 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr2_-_220173685 0.35 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr10_+_88854926 0.32 ENST00000298784.1
ENST00000298786.4
FAM35A
family with sequence similarity 35, member A
chr11_-_57417405 0.32 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr2_+_166326157 0.31 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr10_-_31288398 0.30 ENST00000538351.2
ZNF438
zinc finger protein 438
chr2_+_12246664 0.30 ENST00000449986.1
AC096559.1
AC096559.1
chrY_+_15016725 0.29 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_+_145317356 0.29 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr17_-_1553346 0.28 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr2_-_145275228 0.28 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr3_+_98699880 0.28 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr12_-_76817036 0.28 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr3_-_48632593 0.28 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr4_+_175839506 0.26 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr3_-_49395705 0.25 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr1_-_160231451 0.25 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr9_+_140135665 0.25 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr7_+_147830776 0.25 ENST00000538075.1
CNTNAP2
contactin associated protein-like 2
chr16_+_89988259 0.25 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr19_-_35992780 0.25 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr5_+_177540444 0.25 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chrX_+_47053208 0.24 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr9_-_21335240 0.24 ENST00000537938.1
KLHL9
kelch-like family member 9
chr7_-_122342988 0.23 ENST00000434824.1
RNF148
ring finger protein 148
chr4_+_175839551 0.23 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr17_-_47785504 0.22 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1
solute carrier family 35, member B1
chr1_-_166944561 0.22 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr9_-_23826298 0.22 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr19_-_46285646 0.22 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr13_-_41593425 0.21 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chrX_-_153285395 0.21 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr16_-_69760409 0.21 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr8_-_82395461 0.20 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chrX_-_153285251 0.20 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr14_+_103801140 0.20 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5
eukaryotic translation initiation factor 5
chr9_+_44867571 0.20 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr7_-_122342966 0.20 ENST00000447240.1
RNF148
ring finger protein 148
chr12_-_6960407 0.19 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr2_-_74757066 0.18 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chr14_+_73525144 0.18 ENST00000261973.7
ENST00000540173.1
RBM25
RNA binding motif protein 25
chr10_+_121410882 0.17 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chrX_+_57618269 0.17 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr9_-_91793675 0.17 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr3_-_45957088 0.17 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr3_-_45957534 0.16 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr14_+_73525229 0.16 ENST00000527432.1
ENST00000531500.1
ENST00000525321.1
ENST00000526754.1
RBM25
RNA binding motif protein 25
chr1_+_151227179 0.16 ENST00000368884.3
ENST00000368881.4
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr7_-_14942283 0.15 ENST00000402815.1
DGKB
diacylglycerol kinase, beta 90kDa
chrX_-_70326455 0.14 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr4_-_36246060 0.14 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_49755019 0.14 ENST00000304801.3
PGK2
phosphoglycerate kinase 2
chr3_+_191046810 0.14 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr3_+_155860751 0.14 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_-_51561784 0.14 ENST00000360392.4
TRIM9
tripartite motif containing 9
chrX_+_133371077 0.14 ENST00000517294.1
ENST00000370809.4
CCDC160
coiled-coil domain containing 160
chr14_+_73525265 0.13 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr2_+_169926047 0.13 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr16_+_3692931 0.13 ENST00000407479.1
DNASE1
deoxyribonuclease I
chr2_-_11606275 0.12 ENST00000381525.3
ENST00000362009.4
E2F6
E2F transcription factor 6
chr11_-_66103867 0.12 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr3_+_19988885 0.12 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr1_-_244006528 0.11 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_-_150721570 0.11 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr18_+_2846972 0.11 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr6_+_125540951 0.11 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr1_+_15943995 0.11 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr3_+_138153451 0.11 ENST00000389567.4
ENST00000289135.4
ESYT3
extended synaptotagmin-like protein 3
chr6_-_31704282 0.10 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr15_-_54025300 0.10 ENST00000559418.1
WDR72
WD repeat domain 72
chr19_+_13842559 0.09 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr2_+_47596287 0.09 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr1_+_26606608 0.09 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_13007420 0.08 ENST00000376189.1
PRAMEF6
PRAME family member 6
chr19_+_3366547 0.08 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr7_+_23286182 0.07 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr16_+_14280564 0.07 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr9_-_21335356 0.07 ENST00000359039.4
KLHL9
kelch-like family member 9
chr10_-_90611566 0.07 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr11_-_66103932 0.07 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr17_-_73150629 0.07 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chrX_-_154493791 0.06 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr1_-_13117736 0.06 ENST00000376192.5
ENST00000376182.1
PRAMEF6
PRAME family member 6
chr19_-_51872233 0.05 ENST00000601435.1
ENST00000291715.1
CLDND2
claudin domain containing 2
chr12_-_57914275 0.04 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr20_-_62129163 0.04 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr7_-_55606346 0.04 ENST00000545390.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr6_+_56819895 0.04 ENST00000370748.3
BEND6
BEN domain containing 6
chr12_+_113860160 0.04 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL
serine dehydratase-like
chr12_+_113860042 0.03 ENST00000403593.4
SDSL
serine dehydratase-like
chr10_+_1102721 0.03 ENST00000263150.4
WDR37
WD repeat domain 37
chr2_+_68872954 0.03 ENST00000394342.2
PROKR1
prokineticin receptor 1
chr19_-_51538118 0.02 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr9_+_34958254 0.02 ENST00000242315.3
KIAA1045
KIAA1045
chr16_+_30077055 0.01 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_233897382 0.01 ENST00000233840.3
NEU2
sialidase 2 (cytosolic sialidase)
chr18_+_61442629 0.01 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr4_+_120056939 0.01 ENST00000307128.5
MYOZ2
myozenin 2
chr1_+_13359819 0.01 ENST00000376168.1
PRAMEF5
PRAME family member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 37.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.2 4.8 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.7 2.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.7 2.0 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.7 2.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.6 1.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 1.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3 1.3 GO:0006218 uridine catabolic process(GO:0006218)
0.3 1.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3 0.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.3 0.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3 3.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 0.8 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 6.6 GO:0030728 ovulation(GO:0030728)
0.2 0.9 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 0.8 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 4.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 2.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.4 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:1904207 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 4.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.3 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 1.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.6 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 1.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.3 GO:1902903 regulation of fibril organization(GO:1902903)
0.1 3.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 2.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.5 GO:0090197 positive regulation of chemokine secretion(GO:0090197)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 2.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 1.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.0 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.0 3.1 GO:0005607 laminin-2 complex(GO:0005607)
0.7 2.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 37.4 GO:0015030 Cajal body(GO:0015030)
0.3 1.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.3 0.9 GO:0044753 amphisome(GO:0044753)
0.2 1.5 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.0 GO:1990037 Lewy body core(GO:1990037)
0.2 1.5 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.1 0.3 GO:0097413 Lewy body(GO:0097413)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 6.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.1 GO:0033010 paranodal junction(GO:0033010)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.5 37.4 GO:0008859 exoribonuclease II activity(GO:0008859)
1.0 3.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.0 4.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 1.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 1.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 1.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 6.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.6 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 3.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 4.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.0 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.1 ST GAQ PATHWAY G alpha q Pathway
0.0 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 4.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 9.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 6.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 37.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 7.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 5.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 3.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 4.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network