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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for JUN

Z-value: 0.88

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Transcription factors associated with JUN

Gene Symbol Gene ID Gene Info
JUN
ENSG00000177606.5 Jun proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNhg19_v2_chr1_-_59249732_59249785-0.404.7e-02Click!

Activity profile of JUN motif

Sorted Z-values of JUN motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_61554932 3.41 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_+_113344755 3.18 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_+_45504688 2.59 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr14_+_96671016 2.57 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr11_-_8832182 2.56 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5
suppression of tumorigenicity 5
chr11_-_72496976 2.54 ENST00000539138.1
ENST00000542989.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr5_+_113697983 2.48 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_2039946 2.43 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr11_-_1593150 2.34 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr17_-_34207295 2.20 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr7_-_92777606 2.15 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr12_+_113344582 2.11 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr11_-_64647144 1.87 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1
EH-domain containing 1
chr1_-_32264356 1.82 ENST00000452755.2
SPOCD1
SPOC domain containing 1
chr16_+_50776021 1.77 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_50775971 1.58 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr5_-_95297678 1.55 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr16_+_50775948 1.55 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr2_-_220264703 1.50 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr12_+_113344811 1.50 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_129240151 1.49 ENST00000305031.4
CHSY3
chondroitin sulfate synthase 3
chr5_-_95297534 1.46 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr19_+_49109990 1.40 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chr16_+_3115323 1.36 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
IL32
interleukin 32
chr16_+_3115298 1.36 ENST00000325568.5
ENST00000534507.1
IL32
interleukin 32
chr9_+_111624577 1.36 ENST00000333999.3
ACTL7A
actin-like 7A
chr16_+_31044413 1.36 ENST00000394998.1
STX4
syntaxin 4
chr16_+_3115378 1.35 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
IL32
interleukin 32
chr19_-_50979981 1.35 ENST00000595790.1
ENST00000600100.1
FAM71E1
family with sequence similarity 71, member E1
chr16_+_3115611 1.32 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
IL32
interleukin 32
chr17_+_32646055 1.30 ENST00000394620.1
CCL8
chemokine (C-C motif) ligand 8
chr14_+_59655369 1.27 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1
dishevelled associated activator of morphogenesis 1
chr12_+_75874984 1.25 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr6_-_3157760 1.25 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr11_+_6226782 1.24 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr12_+_75874580 1.22 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr3_-_50374869 1.22 ENST00000327761.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr11_-_3078838 1.21 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr8_-_119124045 1.21 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr17_-_8151353 1.20 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr9_-_130477912 1.18 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr4_+_86525299 1.16 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr1_-_154600421 1.15 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr22_+_38597889 1.15 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr5_-_133304473 1.14 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr1_-_89736434 1.13 ENST00000370459.3
GBP5
guanylate binding protein 5
chr14_-_75389975 1.13 ENST00000555647.1
ENST00000557413.1
RPS6KL1
ribosomal protein S6 kinase-like 1
chr11_-_65430554 1.12 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_6739662 1.07 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr12_-_18890940 1.06 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr16_+_2564254 1.03 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_-_49124230 1.03 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr8_-_27115931 1.02 ENST00000523048.1
STMN4
stathmin-like 4
chr17_-_1083078 1.01 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr18_+_23806437 1.01 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_166808692 1.00 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr11_-_65430251 0.99 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr6_+_126277842 0.98 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr1_+_17866290 0.97 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_31543334 0.97 ENST00000449264.2
TNF
tumor necrosis factor
chr7_-_140624499 0.97 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr22_+_25003606 0.97 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr11_+_33061543 0.97 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr11_+_117070037 0.96 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr19_+_17666403 0.96 ENST00000252599.4
COLGALT1
collagen beta(1-O)galactosyltransferase 1
chr16_+_85942594 0.94 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr1_-_16482554 0.94 ENST00000358432.5
EPHA2
EPH receptor A2
chr10_+_23983671 0.93 ENST00000376462.1
KIAA1217
KIAA1217
chr19_+_49622646 0.92 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr7_+_5632436 0.92 ENST00000340250.6
ENST00000382361.3
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr15_+_42841008 0.92 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr6_-_46293378 0.91 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr10_+_124134201 0.90 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_125740514 0.88 ENST00000325064.5
ENST00000518547.1
MTSS1
metastasis suppressor 1
chr9_+_135457530 0.88 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr8_-_125740730 0.87 ENST00000354184.4
MTSS1
metastasis suppressor 1
chr19_+_36119975 0.86 ENST00000589559.1
ENST00000360475.4
RBM42
RNA binding motif protein 42
chr21_-_43430440 0.85 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chrX_-_83757399 0.85 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr11_+_5423827 0.84 ENST00000332043.1
OR51J1
olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)
chr18_+_11490077 0.84 ENST00000586947.1
ENST00000591431.1
RP11-712C7.1
RP11-712C7.1
chr1_+_25071848 0.84 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr9_+_34989638 0.84 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr7_-_100493744 0.82 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr3_+_38206975 0.82 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr12_-_58165870 0.81 ENST00000257848.7
METTL1
methyltransferase like 1
chr7_+_28725585 0.80 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr4_-_69536346 0.80 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr21_-_35899113 0.80 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr1_+_28099683 0.80 ENST00000373943.4
STX12
syntaxin 12
chr19_+_36120009 0.79 ENST00000589871.1
RBM42
RNA binding motif protein 42
chr11_+_102217936 0.79 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr19_+_35849362 0.79 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr18_+_32073253 0.79 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr19_+_44081344 0.78 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr10_-_105615164 0.78 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr14_+_23352374 0.78 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr19_+_35862192 0.75 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr20_+_33146510 0.75 ENST00000397709.1
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr1_+_40713573 0.74 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr19_+_35861831 0.74 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr19_+_35849723 0.73 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr18_+_72163443 0.73 ENST00000324262.4
ENST00000580672.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chrX_+_102965835 0.73 ENST00000319560.6
TMEM31
transmembrane protein 31
chr11_-_5531215 0.73 ENST00000311659.4
UBQLN3
ubiquilin 3
chr19_+_10362882 0.72 ENST00000393733.2
ENST00000588502.1
MRPL4
mitochondrial ribosomal protein L4
chr19_+_10362577 0.72 ENST00000592514.1
ENST00000307422.5
ENST00000253099.6
ENST00000590150.1
ENST00000590669.1
MRPL4
mitochondrial ribosomal protein L4
chr10_+_123923105 0.72 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr10_+_123922941 0.72 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_+_36119929 0.71 ENST00000588161.1
ENST00000262633.4
ENST00000592202.1
ENST00000586618.1
RBM42
RNA binding motif protein 42
chr7_+_154720173 0.71 ENST00000397551.2
PAXIP1-AS2
PAXIP1 antisense RNA 2
chr20_+_58179582 0.70 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr5_+_156696362 0.70 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr9_+_34990219 0.70 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_+_30751953 0.70 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr1_-_205904950 0.70 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr3_+_148447887 0.69 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chrX_-_68385354 0.68 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr3_-_119182523 0.68 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr12_-_323689 0.68 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr19_+_18043810 0.68 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chrX_-_68385274 0.68 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_-_1112141 0.67 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr6_+_151042224 0.67 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr19_-_44100275 0.67 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr10_+_27444268 0.67 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr6_+_43211418 0.67 ENST00000259750.4
TTBK1
tau tubulin kinase 1
chr11_+_18416103 0.66 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
LDHA
lactate dehydrogenase A
chr17_-_72864739 0.65 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr6_-_53213587 0.65 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
ELOVL5
ELOVL fatty acid elongase 5
chr18_+_72163536 0.64 ENST00000579847.1
ENST00000583203.1
ENST00000581513.1
ENST00000577600.1
ENST00000579583.1
ENST00000584613.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr10_+_123923205 0.64 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr11_+_18416133 0.64 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
LDHA
lactate dehydrogenase A
chr8_-_103876383 0.63 ENST00000347770.4
AZIN1
antizyme inhibitor 1
chr18_-_5540471 0.63 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr14_+_35515598 0.63 ENST00000280987.4
FAM177A1
family with sequence similarity 177, member A1
chr4_+_81187753 0.63 ENST00000312465.7
ENST00000456523.3
FGF5
fibroblast growth factor 5
chr5_-_16916624 0.63 ENST00000513882.1
MYO10
myosin X
chr19_-_46088068 0.63 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr19_+_17830051 0.62 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr2_+_37571717 0.62 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr2_+_74757050 0.62 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr11_-_3818688 0.62 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr9_-_34048873 0.62 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2
ubiquitin associated protein 2
chr2_+_37571845 0.62 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr1_-_32860020 0.61 ENST00000527163.1
ENST00000341071.7
ENST00000530485.1
ENST00000446293.2
ENST00000413080.1
ENST00000449308.1
ENST00000526031.1
ENST00000419121.2
ENST00000455895.2
BSDC1
BSD domain containing 1
chr20_-_48530230 0.61 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr4_+_1873155 0.60 ENST00000507820.1
ENST00000514045.1
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr16_-_79634595 0.60 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr5_+_172332220 0.60 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr3_-_107941209 0.60 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr7_-_45026159 0.60 ENST00000584327.1
ENST00000438705.3
SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr8_+_86121448 0.60 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr12_-_52604607 0.59 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr15_-_41047421 0.59 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
RMDN3
regulator of microtubule dynamics 3
chr19_+_36024310 0.59 ENST00000222286.4
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_41888926 0.59 ENST00000230340.4
BYSL
bystin-like
chr4_-_119759795 0.58 ENST00000419654.2
SEC24D
SEC24 family member D
chr10_+_134351319 0.58 ENST00000368594.3
ENST00000368593.3
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr5_-_54281407 0.57 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr17_+_31318886 0.57 ENST00000269053.3
ENST00000394638.1
SPACA3
sperm acrosome associated 3
chr1_+_22307592 0.57 ENST00000400277.2
CELA3B
chymotrypsin-like elastase family, member 3B
chr7_-_45026200 0.56 ENST00000577700.1
ENST00000580458.1
ENST00000579383.1
ENST00000584686.1
ENST00000585030.1
ENST00000582727.1
SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr17_+_685513 0.56 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr12_+_6833237 0.56 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr17_+_29421900 0.56 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr2_+_70142189 0.55 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr12_-_16761007 0.55 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_-_38713428 0.55 ENST00000403904.1
ENST00000405675.3
CSNK1E
casein kinase 1, epsilon
chr11_-_123525289 0.55 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr2_-_202645612 0.55 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr7_-_45026419 0.55 ENST00000578968.1
ENST00000580528.1
SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr6_+_30130969 0.55 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr20_+_44420570 0.55 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr6_+_37225540 0.54 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr19_-_48614063 0.54 ENST00000599921.1
ENST00000599111.1
PLA2G4C
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr11_-_117699413 0.54 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chrX_+_15767971 0.54 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr2_+_54785485 0.54 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_+_118965244 0.53 ENST00000515256.1
ENST00000509264.1
FAM170A
family with sequence similarity 170, member A
chr17_-_71308119 0.53 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr8_-_95274536 0.53 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr7_-_142176790 0.52 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr20_+_34203794 0.52 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr8_+_40010989 0.52 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr20_+_33292068 0.52 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr4_-_79860506 0.52 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr12_+_6833437 0.52 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COPS7A
COP9 signalosome subunit 7A
chr20_+_42295745 0.52 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr7_-_41742697 0.51 ENST00000242208.4
INHBA
inhibin, beta A
chr19_-_56826157 0.51 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr11_-_104817919 0.51 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr7_+_117120106 0.51 ENST00000426809.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr19_+_38794797 0.51 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr10_+_24528108 0.51 ENST00000438429.1
KIAA1217
KIAA1217
chr12_+_100660909 0.51 ENST00000549687.1
SCYL2
SCY1-like 2 (S. cerevisiae)
chr6_-_34664612 0.51 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr14_-_69261310 0.50 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr7_+_30174426 0.50 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr20_+_44420617 0.50 ENST00000449078.1
ENST00000456939.1
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of JUN

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.6 2.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5 2.1 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.5 1.4 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4 2.7 GO:0030035 microspike assembly(GO:0030035)
0.4 1.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.4 1.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.4 1.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.4 1.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 1.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 1.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.3 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 1.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.3 1.3 GO:0007343 egg activation(GO:0007343)
0.3 0.9 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 0.9 GO:0048320 axial mesoderm formation(GO:0048320)
0.3 1.9 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 2.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.3 0.8 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 0.8 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 2.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 0.8 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.3 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 0.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 2.5 GO:0032782 bile acid secretion(GO:0032782)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 1.2 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.8 GO:0009386 translational attenuation(GO:0009386)
0.2 1.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.2 0.5 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.5 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.2 0.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 1.1 GO:0048539 bone marrow development(GO:0048539)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 2.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.1 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 2.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 1.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.5 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 1.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.6 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255) cellular amide catabolic process(GO:0043605)
0.1 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 3.8 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.1 0.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.1 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.4 GO:0060268 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.1 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.2 GO:0060460 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) superior vena cava morphogenesis(GO:0060578)
0.1 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0046066 dGDP metabolic process(GO:0046066)
0.1 0.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 2.2 GO:0007567 parturition(GO:0007567)
0.1 0.4 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.2 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 1.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 6.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.1 2.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0060702 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0061110 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.9 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 3.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.9 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.5 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.5 GO:0031272 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.4 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.4 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:2000322 regulation of glucocorticoid receptor signaling pathway(GO:2000322) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.9 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.6 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 1.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0030200 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 2.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.0 GO:1901253 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.5 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 1.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.9 GO:0030901 midbrain development(GO:0030901)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.6 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.9 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.8 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.6 GO:0009798 axis specification(GO:0009798)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.0 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.4 1.9 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 2.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 0.8 GO:0031523 Myb complex(GO:0031523)
0.2 2.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.9 GO:1990742 microvesicle(GO:1990742)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 0.7 GO:0097447 dendritic tree(GO:0097447)
0.2 1.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 0.9 GO:0044393 microspike(GO:0044393)
0.2 0.5 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.5 GO:0000322 storage vacuole(GO:0000322)
0.1 1.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 5.6 GO:0097542 ciliary tip(GO:0097542)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 2.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0044754 autolysosome(GO:0044754)
0.0 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 2.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 2.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.2 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 6.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5 2.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 1.4 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.4 1.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.4 1.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.4 4.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 1.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 1.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.3 0.9 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.3 1.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 0.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 1.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.7 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.2 0.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 1.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 2.2 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.9 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 4.0 GO:0005125 cytokine activity(GO:0005125)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0002039 p53 binding(GO:0002039)
0.0 2.9 GO:0001047 core promoter binding(GO:0001047)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.5 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 5.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 8.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 2.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 3.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 3.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)