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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for KLF12

Z-value: 0.86

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_747084090.272.0e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_137801160 4.22 ENST00000239938.4
EGR1
early growth response 1
chr17_-_47841485 3.26 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr2_-_225266711 2.74 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr2_-_225266743 2.73 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr13_+_58206655 2.73 ENST00000377918.3
PCDH17
protocadherin 17
chr3_+_193853927 2.71 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr15_-_52944231 2.41 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr6_+_116832789 2.25 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr1_+_61330931 2.08 ENST00000371191.1
NFIA
nuclear factor I/A
chr9_-_134151915 2.03 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr11_+_7534999 1.78 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_148804275 1.71 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr1_+_92495528 1.51 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr2_+_234104079 1.50 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr9_-_100459639 1.48 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr20_+_34713312 1.42 ENST00000373946.3
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_34742650 1.39 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_203499901 1.35 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr10_-_81205373 1.31 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr14_+_58765103 1.28 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr5_-_81046841 1.25 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr2_-_220435963 1.25 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr14_+_74417192 1.24 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr1_-_45672221 1.10 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr14_+_61788429 1.07 ENST00000332981.5
PRKCH
protein kinase C, eta
chr7_-_27224842 1.06 ENST00000517402.1
HOXA11
homeobox A11
chr7_-_27224795 1.05 ENST00000006015.3
HOXA11
homeobox A11
chr17_+_1665253 1.02 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr22_+_47016277 1.01 ENST00000406902.1
GRAMD4
GRAM domain containing 4
chr11_+_121461097 1.00 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_96184533 0.96 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr13_-_67804445 0.96 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr11_-_102401469 0.95 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr12_-_46766577 0.94 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr12_+_12878829 0.93 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr12_+_79258547 0.93 ENST00000457153.2
SYT1
synaptotagmin I
chr19_+_13051206 0.92 ENST00000586760.1
CALR
calreticulin
chr13_-_67802549 0.91 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr7_+_140373619 0.91 ENST00000483369.1
ADCK2
aarF domain containing kinase 2
chr12_+_79258444 0.89 ENST00000261205.4
SYT1
synaptotagmin I
chr14_-_92413353 0.86 ENST00000556154.1
FBLN5
fibulin 5
chr11_-_61129335 0.86 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chr5_-_81046904 0.86 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr2_+_24272576 0.85 ENST00000380986.4
ENST00000452109.1
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr14_+_63671105 0.82 ENST00000316754.3
RHOJ
ras homolog family member J
chr17_+_42634844 0.80 ENST00000315323.3
FZD2
frizzled family receptor 2
chr2_+_89999259 0.79 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr2_+_24272543 0.79 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr19_+_36602104 0.76 ENST00000585332.1
ENST00000262637.4
OVOL3
ovo-like zinc finger 3
chr6_-_31864977 0.76 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr11_-_2160180 0.76 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_-_107006596 0.73 ENST00000333274.6
EFNA5
ephrin-A5
chr16_+_3019246 0.73 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr18_+_29598335 0.72 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr11_-_62474803 0.72 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_29819096 0.71 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_24737089 0.71 ENST00000483544.1
LINC00477
long intergenic non-protein coding RNA 477
chr19_+_46000479 0.67 ENST00000456399.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_+_49917751 0.66 ENST00000325239.5
ENST00000413659.2
WDFY4
WDFY family member 4
chrX_-_74743080 0.65 ENST00000373367.3
ZDHHC15
zinc finger, DHHC-type containing 15
chr17_-_39150385 0.65 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr19_+_46000506 0.64 ENST00000396737.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_-_77161650 0.63 ENST00000372524.4
ZNF503
zinc finger protein 503
chr3_-_49722523 0.63 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_+_29819372 0.62 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_6772303 0.62 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr14_-_23288930 0.61 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_-_140178775 0.61 ENST00000474576.1
ENST00000473444.1
ENST00000471104.1
MKRN1
makorin ring finger protein 1
chr17_-_8534031 0.61 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10
myosin, heavy chain 10, non-muscle
chrX_-_10544942 0.60 ENST00000380779.1
MID1
midline 1 (Opitz/BBB syndrome)
chr16_+_29819446 0.59 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_-_103880209 0.59 ENST00000425280.1
LDB1
LIM domain binding 1
chr17_-_76899275 0.58 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr17_-_8534067 0.58 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr7_-_27702455 0.58 ENST00000265395.2
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr14_+_75469606 0.57 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr11_+_103907308 0.56 ENST00000302259.3
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr4_-_74904398 0.55 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr17_+_27071002 0.55 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr1_-_46598371 0.54 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr16_+_75256507 0.53 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr2_+_219745020 0.53 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_-_122635754 0.53 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr16_+_28875126 0.52 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr3_+_148508845 0.52 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr1_-_203144941 0.52 ENST00000255416.4
MYBPH
myosin binding protein H
chr16_+_29818857 0.52 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_2240775 0.52 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr3_-_49058479 0.51 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr12_+_7055631 0.51 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr15_+_74218787 0.51 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr19_-_2050852 0.50 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr15_+_40531621 0.50 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr9_+_126131131 0.48 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr1_+_178694300 0.48 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr19_+_45312347 0.47 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr16_-_790982 0.47 ENST00000301694.5
ENST00000251588.2
NARFL
nuclear prelamin A recognition factor-like
chr22_-_39268192 0.47 ENST00000216083.6
CBX6
chromobox homolog 6
chr12_+_50366620 0.46 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr1_-_76398077 0.46 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr12_+_7060432 0.46 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_-_71148413 0.45 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr11_-_1643368 0.45 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr1_+_6845497 0.45 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr7_-_65447192 0.45 ENST00000421103.1
ENST00000345660.6
ENST00000304895.4
GUSB
glucuronidase, beta
chr1_+_16083154 0.43 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr9_-_127952187 0.43 ENST00000451402.1
ENST00000415905.1
PPP6C
protein phosphatase 6, catalytic subunit
chr12_+_107168418 0.42 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr14_+_57857262 0.42 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr15_+_40531243 0.42 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_113933581 0.41 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr7_+_107220899 0.41 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr14_-_75530693 0.41 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr14_-_74416829 0.41 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr11_+_36616044 0.40 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chrX_+_54835493 0.40 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr20_+_61867235 0.39 ENST00000342412.6
ENST00000217169.3
BIRC7
baculoviral IAP repeat containing 7
chr6_-_43021612 0.39 ENST00000535468.1
CUL7
cullin 7
chr12_-_71148357 0.38 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_74632993 0.38 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr14_+_85996471 0.38 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr14_+_74416989 0.38 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr8_+_145691411 0.37 ENST00000301332.2
KIFC2
kinesin family member C2
chr19_+_5914213 0.37 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS
calcyphosine
chr16_-_790887 0.37 ENST00000540986.1
NARFL
nuclear prelamin A recognition factor-like
chr7_+_107220660 0.36 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr12_-_4554780 0.36 ENST00000228837.2
FGF6
fibroblast growth factor 6
chrX_-_112084043 0.36 ENST00000304758.1
AMOT
angiomotin
chr1_+_53068020 0.36 ENST00000361314.4
GPX7
glutathione peroxidase 7
chr10_-_91403625 0.36 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr22_-_31742218 0.36 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr14_+_104182105 0.36 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr14_+_85996507 0.35 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_-_127952032 0.35 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr1_-_202777535 0.35 ENST00000367264.2
KDM5B
lysine (K)-specific demethylase 5B
chr6_-_33267101 0.35 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chrX_-_129299847 0.34 ENST00000319908.3
ENST00000287295.3
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr2_-_89247338 0.34 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr1_+_109792641 0.34 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr19_-_45909585 0.34 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr10_+_76586348 0.34 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr14_+_104182061 0.34 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr13_-_100624012 0.33 ENST00000267294.4
ZIC5
Zic family member 5
chr16_-_27561209 0.33 ENST00000356183.4
ENST00000561623.1
GTF3C1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr1_-_153600656 0.33 ENST00000339556.4
ENST00000440685.2
S100A13
S100 calcium binding protein A13
chr17_+_900342 0.32 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr12_+_107168342 0.32 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chrX_-_54209640 0.32 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr12_-_54691668 0.31 ENST00000553198.1
NFE2
nuclear factor, erythroid 2
chr11_-_5323226 0.31 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr9_-_99064429 0.31 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr10_+_99473455 0.31 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chr17_+_4618734 0.31 ENST00000571206.1
ARRB2
arrestin, beta 2
chr12_-_55028664 0.31 ENST00000547511.1
ENST00000257867.4
LACRT
lacritin
chr17_-_17942473 0.31 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
chr2_-_128400788 0.30 ENST00000409286.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr12_-_109125285 0.30 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr10_+_104404218 0.30 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr6_-_111804393 0.30 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr20_-_2821271 0.30 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr11_+_20620946 0.30 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr12_+_120907622 0.30 ENST00000392509.2
ENST00000549649.1
ENST00000548342.1
DYNLL1
dynein, light chain, LC8-type 1
chr20_-_2821756 0.29 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chrX_-_129299638 0.29 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chrX_-_45060135 0.29 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr1_-_155177677 0.29 ENST00000368378.3
ENST00000541990.1
ENST00000457183.2
THBS3
thrombospondin 3
chr14_+_63671577 0.29 ENST00000555125.1
RHOJ
ras homolog family member J
chr4_-_73935409 0.29 ENST00000507544.2
ENST00000295890.4
COX18
COX18 cytochrome C oxidase assembly factor
chr9_-_130533615 0.29 ENST00000373277.4
SH2D3C
SH2 domain containing 3C
chrX_+_152953505 0.28 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chrX_+_107334895 0.28 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr20_+_34287364 0.28 ENST00000374072.1
ENST00000397416.1
ENST00000336695.4
ROMO1
reactive oxygen species modulator 1
chr13_-_52027134 0.28 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr5_+_74633036 0.28 ENST00000343975.5
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr2_+_32288657 0.28 ENST00000345662.1
SPAST
spastin
chr17_-_36906058 0.27 ENST00000580830.1
PCGF2
polycomb group ring finger 2
chr11_-_5462744 0.27 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr1_+_153600869 0.26 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr8_+_37553261 0.26 ENST00000331569.4
ZNF703
zinc finger protein 703
chr19_+_44116236 0.26 ENST00000417606.1
SRRM5
serine/arginine repetitive matrix 5
chr19_-_46272106 0.26 ENST00000560168.1
SIX5
SIX homeobox 5
chr12_+_129028500 0.26 ENST00000315208.8
TMEM132C
transmembrane protein 132C
chr2_-_89459813 0.26 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr1_-_46598284 0.25 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr3_+_52350335 0.25 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr9_+_96051469 0.25 ENST00000453718.1
WNK2
WNK lysine deficient protein kinase 2
chr6_-_41863098 0.25 ENST00000373006.1
USP49
ubiquitin specific peptidase 49
chr11_-_63993690 0.25 ENST00000394546.2
ENST00000541278.1
TRPT1
tRNA phosphotransferase 1
chr10_-_65028938 0.24 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr16_-_30798492 0.24 ENST00000262525.4
ZNF629
zinc finger protein 629
chr14_-_106174960 0.24 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr3_-_128294929 0.24 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr15_+_40763150 0.24 ENST00000306243.5
ENST00000559991.1
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr6_+_52535878 0.24 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr16_-_29875057 0.24 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr10_-_51371321 0.23 ENST00000602930.1
AGAP8
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr19_-_46272462 0.23 ENST00000317578.6
SIX5
SIX homeobox 5
chr2_+_36923830 0.23 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr12_-_54778471 0.23 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
ZNF385A
zinc finger protein 385A
chr9_-_99064386 0.23 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0098759 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.9 2.7 GO:0042668 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.6 1.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.5 1.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 1.0 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 1.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 1.2 GO:0021592 fourth ventricle development(GO:0021592)
0.3 2.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.3 1.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 1.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 1.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.8 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 2.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.2 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.8 GO:0003150 membranous septum morphogenesis(GO:0003149) muscular septum morphogenesis(GO:0003150)
0.1 0.5 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 2.1 GO:0060272 mesodermal cell fate specification(GO:0007501) embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.9 GO:0032328 alanine transport(GO:0032328)
0.1 0.6 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 1.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 1.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.6 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:1904044 response to aldosterone(GO:1904044)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.5 GO:0014028 notochord formation(GO:0014028)
0.1 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.8 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.2 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 0.4 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.3 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.2 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 2.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.3 GO:0006743 ubiquinone metabolic process(GO:0006743)
0.0 1.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.2 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.6 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.5 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.9 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.3 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.4 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.8 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0061086 regulation of mRNA export from nucleus(GO:0010793) negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.8 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 2.2 GO:0006301 postreplication repair(GO:0006301)
0.0 2.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.0 GO:1900104 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1900246 regulation of RIG-I signaling pathway(GO:0039535) positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.4 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 1.2 GO:0097513 myosin II filament(GO:0097513)
0.2 1.6 GO:1990393 3M complex(GO:1990393)
0.2 1.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.8 GO:0097361 CIA complex(GO:0097361)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 1.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3 1.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.3 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.3 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 2.3 GO:0071949 FAD binding(GO:0071949)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.2 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 1.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 2.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 5.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)