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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for KLF15

Z-value: 0.61

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_1260763050.331.1e-01Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_42276574 1.63 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr4_+_55524085 1.23 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr10_+_112631547 1.10 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr2_+_48757278 1.03 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr1_+_35258592 1.02 ENST00000342280.4
ENST00000450137.1
GJA4
gap junction protein, alpha 4, 37kDa
chr10_+_8096769 0.86 ENST00000346208.3
GATA3
GATA binding protein 3
chr15_+_57668695 0.83 ENST00000281282.5
CGNL1
cingulin-like 1
chr19_-_14201776 0.82 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr9_-_14313641 0.80 ENST00000380953.1
NFIB
nuclear factor I/B
chr10_+_35416223 0.80 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr17_+_42634844 0.79 ENST00000315323.3
FZD2
frizzled family receptor 2
chr5_-_111093081 0.75 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr10_+_35415978 0.74 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr9_-_14314066 0.72 ENST00000397575.3
NFIB
nuclear factor I/B
chr1_-_85930246 0.71 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr20_-_62680984 0.67 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr9_-_14313893 0.64 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr17_-_42277203 0.64 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr1_+_61547405 0.61 ENST00000371189.4
NFIA
nuclear factor I/A
chr1_+_61548225 0.61 ENST00000371187.3
NFIA
nuclear factor I/A
chr2_-_165477971 0.57 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr1_-_47407111 0.51 ENST00000371904.4
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr16_-_30107491 0.50 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr7_+_89841024 0.49 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr2_+_33172012 0.49 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr10_+_35416090 0.49 ENST00000354759.3
CREM
cAMP responsive element modulator
chr7_+_89841000 0.49 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr2_+_33172221 0.48 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr12_+_53443963 0.48 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_149293990 0.48 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr14_+_32546145 0.47 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr13_-_49107303 0.47 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_+_53443680 0.46 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr14_+_24867992 0.45 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr4_-_39640513 0.44 ENST00000511809.1
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr16_+_29819096 0.43 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_19290483 0.43 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr10_+_8096631 0.43 ENST00000379328.3
GATA3
GATA binding protein 3
chr9_-_14693417 0.43 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr6_-_119670919 0.40 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr2_+_45878790 0.40 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr7_-_94285511 0.39 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr10_+_28822417 0.39 ENST00000428935.1
ENST00000420266.1
WAC
WW domain containing adaptor with coiled-coil
chr4_-_114682597 0.39 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr11_-_124632179 0.38 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr21_-_40685504 0.37 ENST00000380800.3
BRWD1
bromodomain and WD repeat domain containing 1
chr3_-_39196049 0.37 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr7_-_94285402 0.36 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr21_+_27107672 0.36 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr4_-_114682936 0.35 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr11_+_3876859 0.34 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr3_+_37903432 0.34 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr12_+_9067123 0.34 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr7_-_154863264 0.34 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr1_-_110933663 0.34 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr12_+_57482877 0.33 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr9_+_101867387 0.33 ENST00000374990.2
ENST00000552516.1
TGFBR1
transforming growth factor, beta receptor 1
chr7_-_94285472 0.32 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr5_-_73937244 0.32 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr17_-_19290117 0.32 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr11_+_67056755 0.32 ENST00000511455.2
ENST00000308440.6
ANKRD13D
ankyrin repeat domain 13 family, member D
chr11_+_64058820 0.32 ENST00000422670.2
KCNK4
potassium channel, subfamily K, member 4
chr19_-_46272106 0.32 ENST00000560168.1
SIX5
SIX homeobox 5
chr11_-_110167352 0.32 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr11_+_64058758 0.31 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr12_-_31744031 0.31 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr11_+_117049910 0.31 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr1_-_110933611 0.31 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr3_-_124774802 0.30 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr10_+_76871229 0.30 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr3_+_14989076 0.30 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr18_-_74207146 0.30 ENST00000443185.2
ZNF516
zinc finger protein 516
chr19_-_14201507 0.30 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr11_-_82782861 0.29 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr22_+_51112800 0.29 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr6_+_32936353 0.29 ENST00000374825.4
BRD2
bromodomain containing 2
chr1_+_203764742 0.28 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr17_+_77681075 0.28 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr12_+_9067327 0.28 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr17_-_42907564 0.28 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr2_+_242255297 0.28 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2
septin 2
chr18_+_56530136 0.27 ENST00000591083.1
ZNF532
zinc finger protein 532
chr7_+_94285637 0.27 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr9_+_101867359 0.26 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr17_-_46178527 0.26 ENST00000393408.3
CBX1
chromobox homolog 1
chr7_-_767249 0.26 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr2_+_242254679 0.26 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr7_+_36192855 0.26 ENST00000534978.1
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr10_+_21823243 0.25 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_+_65821780 0.25 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr1_-_32229523 0.25 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2
brain-specific angiogenesis inhibitor 2
chr12_+_53774423 0.25 ENST00000426431.2
SP1
Sp1 transcription factor
chr3_-_168865522 0.25 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr1_-_32229934 0.24 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr11_-_77531752 0.24 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr11_-_82782952 0.24 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr8_-_29120580 0.24 ENST00000524189.1
KIF13B
kinesin family member 13B
chr3_+_12838161 0.23 ENST00000456430.2
CAND2
cullin-associated and neddylation-dissociated 2 (putative)
chr16_+_81478775 0.23 ENST00000537098.3
CMIP
c-Maf inducing protein
chr11_+_67056867 0.23 ENST00000514166.1
ANKRD13D
ankyrin repeat domain 13 family, member D
chr3_+_111718173 0.22 ENST00000494932.1
TAGLN3
transgelin 3
chr17_-_46178741 0.22 ENST00000581003.1
ENST00000225603.4
CBX1
chromobox homolog 1
chr13_-_110438914 0.22 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr14_-_89883412 0.22 ENST00000557258.1
FOXN3
forkhead box N3
chr7_-_143059780 0.22 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr17_-_17399701 0.22 ENST00000225688.3
ENST00000579152.1
RASD1
RAS, dexamethasone-induced 1
chr10_+_120967072 0.22 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr10_+_21823079 0.22 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr3_+_9851632 0.22 ENST00000426895.4
TTLL3
tubulin tyrosine ligase-like family, member 3
chr9_-_84303269 0.21 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_242255275 0.21 ENST00000391971.2
SEPT2
septin 2
chr3_-_27764190 0.20 ENST00000537516.1
EOMES
eomesodermin
chr1_+_201798269 0.20 ENST00000361565.4
IPO9
importin 9
chr9_-_139891165 0.20 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr3_-_185542761 0.20 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_97187318 0.20 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr16_+_2521500 0.20 ENST00000293973.1
NTN3
netrin 3
chr19_+_17858509 0.20 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr14_+_58765103 0.20 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr10_+_76871353 0.19 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr17_-_58469687 0.19 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr3_-_105587879 0.19 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_+_45003675 0.19 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr2_+_242254507 0.19 ENST00000391973.2
SEPT2
septin 2
chr1_+_37940153 0.19 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_49449350 0.19 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
RHOA
ras homolog family member A
chr16_+_29819372 0.19 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_-_185542817 0.18 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_24495185 0.18 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr3_-_71802760 0.18 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr18_-_48723690 0.18 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr17_-_76921459 0.18 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_61697862 0.18 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr5_-_11904100 0.18 ENST00000359640.2
CTNND2
catenin (cadherin-associated protein), delta 2
chr6_+_24495067 0.18 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr3_-_197282821 0.17 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr5_-_137071689 0.17 ENST00000505853.1
KLHL3
kelch-like family member 3
chr15_-_34629922 0.17 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_244013384 0.17 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr1_-_32801825 0.17 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_-_141257954 0.17 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr17_+_48911942 0.17 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_+_203765437 0.16 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr10_+_27793257 0.16 ENST00000375802.3
RAB18
RAB18, member RAS oncogene family
chr11_-_71159458 0.16 ENST00000355527.3
DHCR7
7-dehydrocholesterol reductase
chr3_+_9851904 0.16 ENST00000547186.1
ENST00000397241.1
ENST00000426827.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr17_-_27333163 0.16 ENST00000360295.9
SEZ6
seizure related 6 homolog (mouse)
chr6_+_41606176 0.16 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr19_-_10047219 0.16 ENST00000264833.4
OLFM2
olfactomedin 2
chr15_-_37393406 0.15 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr15_-_34630234 0.15 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr10_+_181418 0.15 ENST00000403354.1
ENST00000381607.4
ENST00000402736.1
ZMYND11
zinc finger, MYND-type containing 11
chr10_-_52383644 0.15 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr12_-_131323719 0.15 ENST00000392373.2
STX2
syntaxin 2
chr12_-_123215306 0.15 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr19_+_55795493 0.15 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr17_-_27278445 0.15 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr7_+_92158083 0.15 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RBM48
RNA binding motif protein 48
chr16_+_29817841 0.15 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_11457232 0.15 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr7_+_65338230 0.15 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr16_+_29819446 0.15 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_-_25564750 0.14 ENST00000321117.5
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_27332931 0.14 ENST00000442608.3
ENST00000335960.6
SEZ6
seizure related 6 homolog (mouse)
chr10_+_76871454 0.14 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr11_+_1874200 0.14 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr15_-_34875771 0.14 ENST00000267731.7
GOLGA8B
golgin A8 family, member B
chr3_-_71774516 0.14 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr5_+_139505520 0.14 ENST00000333305.3
IGIP
IgA-inducing protein
chr17_-_13505219 0.14 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr7_+_116139744 0.14 ENST00000343213.2
CAV2
caveolin 2
chr11_+_34073872 0.14 ENST00000530820.1
CAPRIN1
cell cycle associated protein 1
chr13_+_95364963 0.14 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr5_+_140254884 0.14 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr9_+_125703282 0.14 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr5_+_139028510 0.14 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr1_-_153895377 0.14 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr1_-_42800860 0.14 ENST00000445886.1
ENST00000361346.1
ENST00000361776.1
FOXJ3
forkhead box J3
chr10_-_74927810 0.14 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
ECD
ecdysoneless homolog (Drosophila)
chr14_+_55738021 0.14 ENST00000313833.4
FBXO34
F-box protein 34
chr17_+_75137034 0.14 ENST00000436233.4
ENST00000443798.4
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr17_-_50236039 0.14 ENST00000451037.2
CA10
carbonic anhydrase X
chr1_+_46049706 0.13 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr1_-_42800614 0.13 ENST00000372572.1
FOXJ3
forkhead box J3
chr10_-_76995769 0.13 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr2_-_20424844 0.13 ENST00000403076.1
ENST00000254351.4
SDC1
syndecan 1
chr6_+_111580508 0.13 ENST00000368847.4
KIAA1919
KIAA1919
chr10_-_76995675 0.13 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr16_+_2205755 0.13 ENST00000326181.6
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr9_+_130911770 0.13 ENST00000372998.1
LCN2
lipocalin 2
chr2_-_39347524 0.13 ENST00000395038.2
ENST00000402219.2
SOS1
son of sevenless homolog 1 (Drosophila)
chr10_+_74927875 0.13 ENST00000242505.6
FAM149B1
family with sequence similarity 149, member B1
chr11_-_73309228 0.12 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr1_+_33207381 0.12 ENST00000401073.2
KIAA1522
KIAA1522
chr8_+_21777159 0.12 ENST00000434536.1
ENST00000252512.9
XPO7
exportin 7
chr5_+_110559784 0.12 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr7_+_66093851 0.12 ENST00000275532.3
KCTD7
potassium channel tetramerization domain containing 7
chr18_+_13218769 0.12 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr3_+_41240986 0.12 ENST00000396185.3
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
chr12_+_112856690 0.12 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.4 1.1 GO:0060940 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.3 1.3 GO:1901536 pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) negative regulation of DNA demethylation(GO:1901536)
0.3 2.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.6 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 1.2 GO:0033216 ferric iron import(GO:0033216)
0.1 0.6 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.5 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.5 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.6 GO:0060214 endocardium formation(GO:0060214)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.4 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.8 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.4 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.1 GO:1901963 regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.1 0.4 GO:0006083 acetate metabolic process(GO:0006083) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:1901725 regulation of histone deacetylase activity(GO:1901725) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.7 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 1.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0072137 mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.9 GO:0048265 response to pain(GO:0048265)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:1902462 transforming growth factor beta activation(GO:0036363) mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.0 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 1.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0000124 SAGA complex(GO:0000124)
0.1 2.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0001940 male pronucleus(GO:0001940)
0.1 0.9 GO:0097227 sperm annulus(GO:0097227)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 1.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.5 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 1.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins