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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for KLF3

Z-value: 0.63

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Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
KLF3
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_386658270.213.1e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_72432950 1.88 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chrX_-_71526741 0.97 ENST00000454225.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr7_+_73703728 0.80 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr12_-_57522813 0.73 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_+_67430339 0.73 ENST00000439724.3
SMAD3
SMAD family member 3
chr19_+_676385 0.70 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr10_+_115438920 0.67 ENST00000429617.1
ENST00000369331.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr22_-_21387127 0.65 ENST00000426145.1
SLC7A4
solute carrier family 7, member 4
chr20_+_55966444 0.64 ENST00000356208.5
ENST00000440234.2
RBM38
RNA binding motif protein 38
chr19_+_8117636 0.58 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr19_+_19322758 0.57 ENST00000252575.6
NCAN
neurocan
chr15_-_62457480 0.56 ENST00000380392.3
C2CD4B
C2 calcium-dependent domain containing 4B
chr17_-_3595181 0.51 ENST00000552050.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_-_127542051 0.51 ENST00000398104.1
MGLL
monoglyceride lipase
chr1_+_110453608 0.50 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr20_+_36531499 0.50 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr19_-_10464570 0.48 ENST00000529739.1
TYK2
tyrosine kinase 2
chr8_-_101348408 0.48 ENST00000519527.1
ENST00000522369.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr4_-_681114 0.46 ENST00000503156.1
MFSD7
major facilitator superfamily domain containing 7
chr7_+_65670186 0.45 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr8_+_123793633 0.43 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr8_+_22102611 0.39 ENST00000306433.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr18_+_61554932 0.38 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_-_64512469 0.38 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_-_53045948 0.38 ENST00000309680.3
KRT2
keratin 2
chr3_-_142166796 0.38 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr19_-_44174330 0.37 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr14_+_22386325 0.36 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr2_+_131369054 0.36 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr4_-_82136114 0.36 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chr14_+_22458631 0.35 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr12_-_57634475 0.35 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr19_+_16308711 0.35 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr8_-_10512569 0.34 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr6_+_80341000 0.34 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr5_+_151151471 0.34 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_133842243 0.34 ENST00000515627.2
AC005355.2
AC005355.2
chr11_-_5462744 0.34 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr3_+_186648307 0.33 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_+_15125954 0.32 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr11_-_4414880 0.32 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr1_-_57045228 0.32 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr11_-_61658853 0.32 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr11_-_65430251 0.32 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_8117881 0.31 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr3_+_11196206 0.31 ENST00000431010.2
HRH1
histamine receptor H1
chr21_-_46348626 0.31 ENST00000517563.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_-_49351148 0.31 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr1_-_38273840 0.30 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr17_+_73997796 0.30 ENST00000586261.1
CDK3
cyclin-dependent kinase 3
chr15_+_75074410 0.30 ENST00000439220.2
CSK
c-src tyrosine kinase
chr16_-_84538218 0.30 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1
TBC/LysM-associated domain containing 1
chrX_-_65253506 0.29 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr1_+_117544366 0.29 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr17_-_8198636 0.28 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr17_+_56270084 0.28 ENST00000225371.5
EPX
eosinophil peroxidase
chr16_+_56969284 0.28 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_-_5531215 0.28 ENST00000311659.4
UBQLN3
ubiquilin 3
chr11_+_65383227 0.28 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr11_-_73471655 0.28 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr2_+_233734994 0.28 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr1_+_159409512 0.28 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr16_-_1843720 0.28 ENST00000415638.3
ENST00000215539.3
IGFALS
insulin-like growth factor binding protein, acid labile subunit
chr9_+_100174344 0.27 ENST00000422139.2
TDRD7
tudor domain containing 7
chrX_-_71526813 0.27 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chrX_-_75005054 0.27 ENST00000373359.2
MAGEE2
melanoma antigen family E, 2
chr11_-_65430554 0.27 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr16_+_66914264 0.26 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr1_+_44457261 0.26 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr11_-_61659006 0.26 ENST00000278829.2
FADS3
fatty acid desaturase 3
chrX_-_71526999 0.26 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr19_+_58838369 0.25 ENST00000329665.4
ZSCAN22
zinc finger and SCAN domain containing 22
chr2_-_136743039 0.25 ENST00000537273.1
DARS
aspartyl-tRNA synthetase
chr11_+_6226782 0.25 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr15_-_78933567 0.25 ENST00000261751.3
ENST00000412074.2
CHRNB4
cholinergic receptor, nicotinic, beta 4 (neuronal)
chr17_+_27181956 0.24 ENST00000254928.5
ENST00000580917.2
ERAL1
Era-like 12S mitochondrial rRNA chaperone 1
chr16_+_618837 0.24 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr19_+_1941117 0.24 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr19_-_5784610 0.24 ENST00000390672.2
ENST00000419421.2
PRR22
proline rich 22
chr21_-_35883541 0.24 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr19_+_14492247 0.24 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr11_-_57194948 0.24 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
SLC43A3
solute carrier family 43, member 3
chr10_+_60028818 0.23 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr8_+_145582633 0.23 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr10_+_101419187 0.23 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr1_-_243326612 0.23 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr1_+_114471809 0.23 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chrX_+_153770421 0.23 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr19_-_44008863 0.23 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr7_+_86273700 0.22 ENST00000546348.1
GRM3
glutamate receptor, metabotropic 3
chr2_-_136743169 0.22 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr13_+_100634004 0.22 ENST00000376335.3
ZIC2
Zic family member 2
chr19_-_46288917 0.22 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr4_+_24797085 0.21 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr15_+_43985084 0.21 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr17_-_32690239 0.21 ENST00000225842.3
CCL1
chemokine (C-C motif) ligand 1
chr15_+_43885252 0.21 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr1_-_60539422 0.21 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr8_+_59465728 0.21 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP
syndecan binding protein (syntenin)
chr1_-_60539405 0.21 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr12_-_96390063 0.20 ENST00000541929.1
HAL
histidine ammonia-lyase
chr11_-_118966167 0.20 ENST00000530167.1
H2AFX
H2A histone family, member X
chr3_-_139199565 0.20 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr20_-_590944 0.20 ENST00000246080.3
TCF15
transcription factor 15 (basic helix-loop-helix)
chr7_+_116165754 0.20 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_+_173315283 0.20 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr20_+_46130671 0.20 ENST00000371998.3
ENST00000371997.3
NCOA3
nuclear receptor coactivator 3
chr19_+_16308659 0.20 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr1_+_18434240 0.19 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chrX_-_119249819 0.19 ENST00000217999.2
RHOXF1
Rhox homeobox family, member 1
chr5_+_151151504 0.19 ENST00000356245.3
ENST00000507878.2
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr11_+_65407331 0.19 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr3_+_14058794 0.19 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr3_-_4793274 0.19 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr22_-_30722866 0.19 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr16_+_2083265 0.19 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr14_-_65569244 0.19 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr14_-_65569057 0.18 ENST00000555419.1
ENST00000341653.2
MAX
MYC associated factor X
chr6_+_37225540 0.18 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr11_-_62313090 0.18 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr8_+_22428457 0.18 ENST00000517962.1
SORBS3
sorbin and SH3 domain containing 3
chr19_+_12902289 0.18 ENST00000302754.4
JUNB
jun B proto-oncogene
chr11_+_118826999 0.18 ENST00000264031.2
UPK2
uroplakin 2
chr8_-_90996837 0.18 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr11_-_73472096 0.18 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
RAB6A
RAB6A, member RAS oncogene family
chr16_+_84209738 0.18 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr16_+_2079501 0.18 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr22_-_50964558 0.18 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr17_+_6926339 0.18 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chrX_+_72062617 0.17 ENST00000440247.1
DMRTC1B
DMRT-like family C1B
chr16_+_30034655 0.17 ENST00000300575.2
C16orf92
chromosome 16 open reading frame 92
chr15_+_75074385 0.17 ENST00000220003.9
CSK
c-src tyrosine kinase
chr13_+_25875662 0.17 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr11_+_46638805 0.17 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
ATG13
autophagy related 13
chr19_-_9929708 0.17 ENST00000247977.4
ENST00000590277.1
ENST00000588922.1
ENST00000589626.1
ENST00000592067.1
ENST00000586469.1
FBXL12
F-box and leucine-rich repeat protein 12
chr22_-_30722912 0.17 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr15_-_58571445 0.17 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_+_119810134 0.17 ENST00000434046.2
SYNPO2
synaptopodin 2
chr1_-_166028709 0.17 ENST00000595430.1
AL626787.1
AL626787.1
chr19_-_6737576 0.17 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr19_-_14016877 0.17 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr11_-_126138808 0.17 ENST00000332118.6
ENST00000532259.1
SRPR
signal recognition particle receptor (docking protein)
chr1_+_213224572 0.17 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr12_+_116997186 0.17 ENST00000306985.4
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chrX_+_38420623 0.16 ENST00000378482.2
TSPAN7
tetraspanin 7
chrX_-_133119670 0.16 ENST00000394299.2
GPC3
glypican 3
chr19_+_44081344 0.16 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr8_+_21911054 0.16 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr16_-_850723 0.16 ENST00000248150.4
GNG13
guanine nucleotide binding protein (G protein), gamma 13
chr2_-_219925189 0.16 ENST00000295731.6
IHH
indian hedgehog
chr16_+_8715536 0.16 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr5_-_149492904 0.16 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr19_-_8675559 0.16 ENST00000597188.1
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr17_+_38171681 0.16 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr3_+_9773409 0.16 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
BRPF1
bromodomain and PHD finger containing, 1
chr13_+_102104952 0.16 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_40755987 0.16 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr22_+_35776828 0.16 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr17_+_28256874 0.15 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr19_-_44174305 0.15 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr8_-_70745575 0.15 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chrX_-_63615297 0.15 ENST00000374852.3
ENST00000453546.1
MTMR8
myotubularin related protein 8
chr1_+_17559776 0.15 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr1_-_204380919 0.15 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr22_-_32341336 0.15 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr19_-_51529849 0.15 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr12_-_96390108 0.15 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr1_+_12851545 0.15 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr8_-_134115118 0.15 ENST00000395352.3
ENST00000338087.5
SLA
Src-like-adaptor
chr21_+_45366811 0.15 ENST00000398058.1
ENST00000457068.1
ENST00000448845.1
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_36789335 0.15 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr16_+_84209539 0.15 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr13_+_25875785 0.15 ENST00000381747.3
NUPL1
nucleoporin like 1
chr2_+_9983483 0.14 ENST00000263663.5
TAF1B
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr16_-_23160591 0.14 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chrX_+_48681768 0.14 ENST00000430858.1
HDAC6
histone deacetylase 6
chr20_+_46130619 0.14 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr12_-_49504655 0.14 ENST00000551782.1
ENST00000267102.8
LMBR1L
limb development membrane protein 1-like
chr11_-_57158109 0.14 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr5_-_118324200 0.14 ENST00000515439.3
ENST00000510708.1
DTWD2
DTW domain containing 2
chr8_-_103876965 0.14 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr15_-_74659978 0.14 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr11_-_35440579 0.14 ENST00000606205.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_101962777 0.14 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr20_-_17641097 0.14 ENST00000246043.4
RRBP1
ribosome binding protein 1
chr2_+_71295733 0.14 ENST00000443938.2
ENST00000244204.6
NAGK
N-acetylglucosamine kinase
chr17_+_38171614 0.14 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr19_-_7553889 0.14 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr9_-_14910420 0.13 ENST00000380880.3
FREM1
FRAS1 related extracellular matrix 1
chr1_+_2005425 0.13 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr17_-_67264947 0.13 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr19_+_45251804 0.13 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr8_-_101963482 0.13 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_+_31637944 0.13 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr19_+_46850320 0.13 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr14_-_65569186 0.13 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MAX
MYC associated factor X
chr4_+_123300664 0.13 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr11_+_8932715 0.13 ENST00000529876.1
ENST00000525005.1
ENST00000524577.1
ENST00000534506.1
AKIP1
A kinase (PRKA) interacting protein 1
chr11_+_111169976 0.13 ENST00000398035.2
COLCA2
colorectal cancer associated 2
chr3_+_57094469 0.13 ENST00000334325.1
SPATA12
spermatogenesis associated 12

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 1.6 GO:0071105 response to interleukin-11(GO:0071105)
0.2 0.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 0.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 0.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.6 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.6 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.7 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.3 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.4 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:0014806 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.2 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.3 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0033159 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0060536 cartilage morphogenesis(GO:0060536)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.5 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 2.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.0 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis