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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for KLF6

Z-value: 0.68

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827371_3827386-0.106.3e-01Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_42277203 2.21 ENST00000587097.1
ataxin 7-like 3
chr19_+_45504688 1.92 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr16_-_11681023 1.71 ENST00000570904.1
ENST00000574701.1
lipopolysaccharide-induced TNF factor
chr1_+_169075554 1.58 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_-_29595779 1.56 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr21_+_43639211 1.33 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr6_+_83073952 1.18 ENST00000543496.1
trophoblast glycoprotein
chr17_-_53499310 1.15 ENST00000262065.3
monocyte to macrophage differentiation-associated
chr6_-_143266297 1.11 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr9_-_95896550 1.06 ENST00000375446.4
ninjurin 1
chr2_+_150187020 1.03 ENST00000334166.4
LY6/PLAUR domain containing 6
chr17_-_42276574 1.00 ENST00000589805.1
ataxin 7-like 3
chr6_+_37137939 0.99 ENST00000373509.5
pim-1 oncogene
chr6_-_137113604 0.97 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr10_-_101380121 0.94 ENST00000370495.4
solute carrier family 25 (mitochondrial iron transporter), member 28
chr3_+_133292759 0.93 ENST00000431519.2
CDV3 homolog (mouse)
chr11_-_72353451 0.92 ENST00000376450.3
phosphodiesterase 2A, cGMP-stimulated
chr6_+_127439749 0.90 ENST00000356698.4
R-spondin 3
chr6_+_37787704 0.88 ENST00000474522.1
zinc finger, AN1-type domain 3
chr8_-_101322132 0.82 ENST00000523481.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_-_114696472 0.79 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
synaptotagmin VI
chr6_+_32811885 0.79 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr17_+_6926339 0.72 ENST00000293805.5
B-cell CLL/lymphoma 6, member B
chr17_-_73874654 0.72 ENST00000254816.2
tripartite motif containing 47
chr15_-_75744014 0.71 ENST00000394947.3
ENST00000565264.1
SIN3 transcription regulator family member A
chr15_-_75743915 0.70 ENST00000394949.4
SIN3 transcription regulator family member A
chr11_-_72492903 0.69 ENST00000537947.1
StAR-related lipid transfer (START) domain containing 10
chr11_+_75526212 0.69 ENST00000356136.3
UV radiation resistance associated
chr15_-_70388943 0.67 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr14_+_93897272 0.66 ENST00000393151.2
unc-79 homolog (C. elegans)
chr19_+_13906250 0.65 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr1_-_205782304 0.62 ENST00000367137.3
solute carrier family 41 (magnesium transporter), member 1
chr22_+_31608219 0.61 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIM domain kinase 2
chr7_+_116165038 0.57 ENST00000393470.1
caveolin 1, caveolae protein, 22kDa
chr6_+_32811861 0.57 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr11_-_3862059 0.57 ENST00000396978.1
ras homolog family member G
chr19_-_47734448 0.56 ENST00000439096.2
BCL2 binding component 3
chr3_-_88108212 0.55 ENST00000482016.1
CGG triplet repeat binding protein 1
chr2_+_219433588 0.54 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_+_4861385 0.53 ENST00000382723.4
msh homeobox 1
chr14_+_93897199 0.52 ENST00000553484.1
unc-79 homolog (C. elegans)
chr19_+_34287174 0.51 ENST00000587559.1
ENST00000588637.1
potassium channel tetramerization domain containing 15
chr16_+_68678739 0.50 ENST00000264012.4
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68678892 0.50 ENST00000429102.2
cadherin 3, type 1, P-cadherin (placental)
chr5_-_94620239 0.49 ENST00000515393.1
multiple C2 domains, transmembrane 1
chr11_+_64008525 0.49 ENST00000449942.2
FK506 binding protein 2, 13kDa
chr2_-_161350305 0.48 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr18_-_51750948 0.47 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr8_-_101321584 0.47 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr8_-_80680078 0.47 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr4_-_6202247 0.46 ENST00000409021.3
ENST00000409371.3
janus kinase and microtubule interacting protein 1
chr3_+_133293278 0.46 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr11_+_64009072 0.46 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr11_+_111473108 0.45 ENST00000304987.3
salt-inducible kinase 2
chr1_-_111746966 0.45 ENST00000369752.5
DENN/MADD domain containing 2D
chr15_-_70388599 0.43 ENST00000560996.1
ENST00000558201.1
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr6_+_31588478 0.42 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr15_+_80987617 0.42 ENST00000258884.4
ENST00000558464.1
abhydrolase domain containing 17C
chr11_-_72492878 0.42 ENST00000535054.1
ENST00000545082.1
StAR-related lipid transfer (START) domain containing 10
chr1_-_6321035 0.39 ENST00000377893.2
G protein-coupled receptor 153
chr10_+_23983671 0.39 ENST00000376462.1
KIAA1217
chr11_-_108464465 0.38 ENST00000525344.1
exophilin 5
chr16_+_75033210 0.37 ENST00000566250.1
ENST00000567962.1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr19_+_10400615 0.37 ENST00000221980.4
intercellular adhesion molecule 5, telencephalin
chr2_+_219433281 0.36 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr5_+_67511524 0.36 ENST00000521381.1
ENST00000521657.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_37430822 0.35 ENST00000378621.3
ENST00000378619.3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr9_+_34989638 0.35 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_+_111878483 0.34 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2-like 11 (apoptosis facilitator)
chr1_-_156698591 0.34 ENST00000368219.1
interferon stimulated exonuclease gene 20kDa-like 2
chr4_+_8201091 0.34 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3 domain and tetratricopeptide repeats 1
chr6_+_44095347 0.34 ENST00000323267.6
transmembrane protein 63B
chr9_+_35605274 0.34 ENST00000336395.5
testis-specific kinase 1
chr16_+_25703274 0.34 ENST00000331351.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr6_-_32811771 0.34 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr1_-_161102213 0.34 ENST00000458050.2
death effector domain containing
chr20_+_37101455 0.34 ENST00000262879.6
ENST00000397042.3
ENST00000397038.1
ENST00000537204.1
Ral GTPase activating protein, beta subunit (non-catalytic)
chr5_+_170846640 0.33 ENST00000274625.5
fibroblast growth factor 18
chr20_+_37101526 0.33 ENST00000397040.1
Ral GTPase activating protein, beta subunit (non-catalytic)
chr12_+_70132632 0.32 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr19_+_10196981 0.32 ENST00000591813.1
chromosome 19 open reading frame 66
chr9_+_100174344 0.32 ENST00000422139.2
tudor domain containing 7
chr16_+_69599899 0.31 ENST00000567239.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr9_-_37465396 0.31 ENST00000307750.4
zinc finger and BTB domain containing 5
chr17_-_60885700 0.31 ENST00000583600.1
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr20_+_48807351 0.31 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr1_-_231004220 0.31 ENST00000366663.5
chromosome 1 open reading frame 198
chr22_-_38484922 0.30 ENST00000428572.1
BAI1-associated protein 2-like 2
chr12_-_49351148 0.30 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr19_+_42724423 0.30 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr20_-_31172598 0.30 ENST00000201961.2
chromosome 20 open reading frame 112
chr11_+_58346584 0.30 ENST00000316059.6
ZFP91 zinc finger protein
chr21_-_35987438 0.29 ENST00000313806.4
regulator of calcineurin 1
chr17_-_60885659 0.29 ENST00000311269.5
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr3_+_38495333 0.29 ENST00000352511.4
activin A receptor, type IIB
chr10_+_35415851 0.29 ENST00000374726.3
cAMP responsive element modulator
chr11_+_66886717 0.29 ENST00000398645.2
lysine (K)-specific demethylase 2A
chr1_+_107683436 0.28 ENST00000370068.1
netrin G1
chr6_+_99282570 0.28 ENST00000328345.5
POU class 3 homeobox 2
chr18_-_48723690 0.28 ENST00000406189.3
mex-3 RNA binding family member C
chr17_-_7120498 0.28 ENST00000485100.1
discs, large homolog 4 (Drosophila)
chr19_+_14672755 0.28 ENST00000594545.1
trans-2,3-enoyl-CoA reductase
chr15_+_52311398 0.28 ENST00000261845.5
mitogen-activated protein kinase 6
chr6_-_31926629 0.28 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr12_+_57482665 0.27 ENST00000300131.3
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_-_25475120 0.27 ENST00000380746.4
ENST00000402667.1
DNA (cytosine-5-)-methyltransferase 3 alpha
chr5_+_38845960 0.27 ENST00000502536.1
oncostatin M receptor
chr18_-_12884150 0.27 ENST00000591115.1
ENST00000309660.5
protein tyrosine phosphatase, non-receptor type 2
chr13_-_27745936 0.27 ENST00000282344.6
ubiquitin specific peptidase 12
chr10_-_75255668 0.27 ENST00000545874.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr20_+_30555805 0.26 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr7_+_116593292 0.26 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
suppression of tumorigenicity 7
chr4_-_174451370 0.26 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr17_-_28257080 0.26 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr6_+_36164487 0.25 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr2_-_161349909 0.25 ENST00000392753.3
RNA binding motif, single stranded interacting protein 1
chr16_+_75032901 0.25 ENST00000335325.4
ENST00000320619.6
zinc and ring finger 1, E3 ubiquitin protein ligase
chr2_+_27071045 0.25 ENST00000401478.1
dihydropyrimidinase-like 5
chr12_-_120554622 0.25 ENST00000229340.5
RAB35, member RAS oncogene family
chr1_+_114472481 0.25 ENST00000369555.2
homeodomain interacting protein kinase 1
chr6_+_31126291 0.25 ENST00000376257.3
ENST00000376255.4
transcription factor 19
chr22_-_17602143 0.25 ENST00000331437.3
cat eye syndrome chromosome region, candidate 6
chr6_-_35656712 0.24 ENST00000357266.4
ENST00000542713.1
FK506 binding protein 5
chr16_+_68679193 0.24 ENST00000581171.1
cadherin 3, type 1, P-cadherin (placental)
chr18_-_12884259 0.24 ENST00000353319.4
ENST00000327283.3
protein tyrosine phosphatase, non-receptor type 2
chr3_+_10290596 0.24 ENST00000448281.2
TatD DNase domain containing 2
chr19_-_41196534 0.24 ENST00000252891.4
numb homolog (Drosophila)-like
chr2_+_220299547 0.24 ENST00000312358.7
SPEG complex locus
chr6_-_82462425 0.24 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr6_-_35656685 0.24 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr7_-_100493482 0.24 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
acetylcholinesterase (Yt blood group)
chr2_-_114514181 0.23 ENST00000409342.1
solute carrier family 35, member F5
chr15_-_100273544 0.23 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LysM, putative peptidoglycan-binding, domain containing 4
chr19_-_10764509 0.23 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr1_+_107682629 0.23 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
netrin G1
chr3_+_10289707 0.23 ENST00000287652.4
TatD DNase domain containing 2
chr19_-_41220957 0.23 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
aarF domain containing kinase 4
chr12_-_120554534 0.23 ENST00000538903.1
ENST00000534951.1
RAB35, member RAS oncogene family
chr9_-_131038266 0.23 ENST00000490628.1
ENST00000421699.2
ENST00000450617.1
golgin A2
chr19_-_10444188 0.23 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr1_-_156698181 0.22 ENST00000313146.6
interferon stimulated exonuclease gene 20kDa-like 2
chr11_-_3862206 0.22 ENST00000351018.4
ras homolog family member G
chr17_+_36861735 0.22 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_-_142782862 0.22 ENST00000415690.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_+_120628731 0.22 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr17_-_7518145 0.21 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chrX_-_49056635 0.21 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
synaptophysin
chr1_-_226924980 0.21 ENST00000272117.3
inositol-trisphosphate 3-kinase B
chr12_-_49351228 0.21 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr6_+_111195973 0.21 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr22_-_17602200 0.20 ENST00000399875.1
cat eye syndrome chromosome region, candidate 6
chr17_-_74449252 0.20 ENST00000319380.7
ubiquitin-conjugating enzyme E2O
chr5_+_56111361 0.20 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr6_+_1389989 0.20 ENST00000259806.1
forkhead box F2
chr7_+_143078652 0.20 ENST00000354434.4
ENST00000449423.2
zyxin
chr2_-_27603582 0.20 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr17_+_28256874 0.20 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr14_-_73925225 0.20 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
numb homolog (Drosophila)
chr14_-_39572345 0.19 ENST00000548032.2
ENST00000556092.1
ENST00000557280.1
ENST00000545328.2
ENST00000553970.1
Sec23 homolog A (S. cerevisiae)
chr17_+_7452442 0.19 ENST00000557233.1
tumor necrosis factor (ligand) superfamily, member 12
chr15_-_66084428 0.19 ENST00000443035.3
ENST00000431932.2
DENN/MADD domain containing 4A
chr17_+_7452336 0.19 ENST00000293826.4
TNFSF12-TNFSF13 readthrough
chr5_-_168006591 0.19 ENST00000239231.6
pantothenate kinase 3
chr17_-_74733404 0.19 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
serine/arginine-rich splicing factor 2
chr4_+_184426147 0.19 ENST00000302327.3
inhibitor of growth family, member 2
chr8_-_125486755 0.19 ENST00000499418.2
ENST00000530778.1
RNF139 antisense RNA 1 (head to head)
chr2_-_30144432 0.18 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr19_-_41196458 0.18 ENST00000598779.1
numb homolog (Drosophila)-like
chr20_+_57466629 0.18 ENST00000371081.1
ENST00000338783.6
GNAS complex locus
chr1_-_23670817 0.18 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr6_-_31926208 0.18 ENST00000454913.1
ENST00000436289.2
negative elongation factor complex member E
chr1_+_6845384 0.18 ENST00000303635.7
calmodulin binding transcription activator 1
chr12_+_57482877 0.18 ENST00000342556.6
ENST00000357680.4
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr12_-_31479107 0.18 ENST00000542983.1
family with sequence similarity 60, member A
chr9_-_101984184 0.18 ENST00000476832.1
ALG2, alpha-1,3/1,6-mannosyltransferase
chr1_-_38273840 0.18 ENST00000373044.2
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr22_+_45680822 0.18 ENST00000216211.4
ENST00000396082.2
uroplakin 3A
chr17_-_1389228 0.18 ENST00000438665.2
myosin IC
chr7_+_143079000 0.18 ENST00000392910.2
zyxin
chr11_+_45907177 0.17 ENST00000241014.2
mitogen-activated protein kinase 8 interacting protein 1
chr10_+_124768482 0.17 ENST00000368869.4
ENST00000358776.4
acyl-CoA dehydrogenase, short/branched chain
chr4_+_183370146 0.17 ENST00000510504.1
teneurin transmembrane protein 3
chr16_+_50582222 0.17 ENST00000268459.3
naked cuticle homolog 1 (Drosophila)
chr1_-_38325256 0.17 ENST00000373036.4
metal-regulatory transcription factor 1
chr16_+_67465016 0.17 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr12_+_124196865 0.17 ENST00000330342.3
ATPase, H+ transporting, lysosomal V0 subunit a2
chr20_+_35201857 0.17 ENST00000373874.2
TGFB-induced factor homeobox 2
chr3_-_113415441 0.17 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr17_-_42143963 0.17 ENST00000585388.1
ENST00000293406.3
LSM12 homolog (S. cerevisiae)
chr19_+_10828724 0.16 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
dynamin 2
chr5_-_142783175 0.16 ENST00000231509.3
ENST00000394464.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_130353553 0.16 ENST00000330992.7
ENST00000445977.2
coatomer protein complex, subunit gamma 2
chr9_-_120177342 0.16 ENST00000361209.2
astrotactin 2
chr14_-_81687575 0.16 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chrX_+_56590002 0.16 ENST00000338222.5
ubiquilin 2
chr1_-_38512450 0.16 ENST00000373012.2
POU class 3 homeobox 1
chr11_+_45868957 0.16 ENST00000443527.2
cryptochrome 2 (photolyase-like)
chr2_+_105471969 0.16 ENST00000361360.2
POU class 3 homeobox 3
chr11_+_65479462 0.16 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
K(lysine) acetyltransferase 5
chr14_+_23790690 0.16 ENST00000556821.1
poly(A) binding protein, nuclear 1

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.4 1.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 1.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.3 1.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.3 0.9 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.6 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.5 GO:0090427 activation of meiosis(GO:0090427)
0.2 0.5 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.3 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 1.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.1 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.9 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 2.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 1.1 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 1.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 1.0 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0090306 Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:1903572 coronary vein morphogenesis(GO:0003169) cardiac vascular smooth muscle cell development(GO:0060948) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 1.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.2 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:0015840 urea transport(GO:0015840) urinary bladder development(GO:0060157)
0.0 0.3 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.5 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0032240 regulation of chromatin assembly(GO:0010847) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 1.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 1.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.0 GO:0021747 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0075713 establishment of integrated proviral latency(GO:0075713)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 3.2 GO:0000124 SAGA complex(GO:0000124)
0.2 1.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 0.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0002060 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0052724 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0070573 peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs