Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for LMX1B_MNX1_RAX2

Z-value: 0.47

Motif logo

logo of logo of logo of

Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LIM homeobox transcription factor 1 beta
MNX1
ENSG00000130675.10 motor neuron and pancreas homeobox 1
RAX2
ENSG00000173976.11 retina and anterior neural fold homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LMX1Bhg19_v2_chr9_+_129376722_129376748-0.193.6e-01Click!
MNX1hg19_v2_chr7_-_156803329_156803362-0.077.4e-01Click!
RAX2hg19_v2_chr19_-_3772209_3772236-0.029.2e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76944621 1.34 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr7_-_92777606 1.21 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr12_+_26348582 0.95 ENST00000535504.1
SSPN
sarcospan
chr2_+_152214098 0.65 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_-_150738261 0.64 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr3_+_173116225 0.62 ENST00000457714.1
NLGN1
neuroligin 1
chr2_-_136678123 0.58 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr17_+_47448102 0.56 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr4_+_169418195 0.54 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr6_-_87804815 0.54 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr11_-_124190184 0.54 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr5_-_24645078 0.54 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr14_-_51027838 0.53 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_-_191000172 0.52 ENST00000427544.2
UTS2B
urotensin 2B
chr12_-_28122980 0.48 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr4_+_169013666 0.47 ENST00000359299.3
ANXA10
annexin A10
chr3_-_157221380 0.46 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr7_-_27169801 0.45 ENST00000511914.1
HOXA4
homeobox A4
chr1_-_101360331 0.41 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr3_-_79816965 0.41 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr7_-_22234381 0.40 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chrX_-_21676442 0.37 ENST00000379499.2
KLHL34
kelch-like family member 34
chr11_+_33061543 0.37 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr3_-_157221357 0.36 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr1_-_152131703 0.35 ENST00000316073.3
RPTN
repetin
chr18_+_32173276 0.35 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr7_+_134464376 0.34 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr12_+_41831485 0.34 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr7_-_92855762 0.34 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr1_-_237167718 0.33 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr1_-_168464875 0.33 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr13_-_46716969 0.33 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_+_41363854 0.32 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr16_+_53133070 0.32 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_-_39979576 0.32 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr3_+_130569429 0.31 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr8_+_105235572 0.28 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr2_-_145277569 0.28 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr3_+_111717511 0.27 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr8_-_109799793 0.27 ENST00000297459.3
TMEM74
transmembrane protein 74
chr1_+_160370344 0.27 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr3_+_111717600 0.27 ENST00000273368.4
TAGLN3
transgelin 3
chr18_-_71959159 0.26 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr2_+_103035102 0.26 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr6_+_105404899 0.26 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr3_+_111718036 0.26 ENST00000455401.2
TAGLN3
transgelin 3
chr8_+_107460147 0.26 ENST00000442977.2
OXR1
oxidation resistance 1
chr1_+_107683436 0.26 ENST00000370068.1
NTNG1
netrin G1
chr17_-_64225508 0.25 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr8_+_50824233 0.25 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr12_-_28123206 0.25 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr19_-_56110859 0.24 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr18_-_33709268 0.23 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_-_139163491 0.23 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_-_110655306 0.23 ENST00000371993.2
DCX
doublecortin
chr3_-_151034734 0.22 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_+_31193847 0.22 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr1_+_68150744 0.22 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr15_+_93443419 0.21 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr11_-_102576537 0.21 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr2_-_61697862 0.21 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr5_+_125758865 0.21 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125758813 0.21 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr21_-_42219065 0.20 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr6_-_161085291 0.20 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr2_-_99871570 0.20 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr10_+_118083919 0.20 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr1_+_101003687 0.19 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr4_+_114214125 0.19 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr17_-_39623681 0.18 ENST00000225899.3
KRT32
keratin 32
chr15_-_55562582 0.18 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr3_-_33686925 0.18 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr10_-_24770632 0.18 ENST00000596413.1
AL353583.1
AL353583.1
chr12_+_26348246 0.18 ENST00000422622.2
SSPN
sarcospan
chr7_+_134464414 0.18 ENST00000361901.2
CALD1
caldesmon 1
chr1_+_155023757 0.18 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM15
ADAM metallopeptidase domain 15
chr12_-_86650045 0.18 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_-_108248169 0.17 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr15_-_55562479 0.17 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 0.17 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr8_+_24298531 0.17 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr8_+_24298597 0.17 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr2_-_208031943 0.16 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr21_+_35736302 0.16 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr2_-_145278475 0.15 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_66300446 0.15 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_157824292 0.15 ENST00000483851.2
SHOX2
short stature homeobox 2
chr12_+_81110684 0.15 ENST00000228644.3
MYF5
myogenic factor 5
chr12_+_93096619 0.15 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr3_-_141747950 0.15 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_71458012 0.15 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr1_+_50569575 0.14 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr9_+_82188077 0.14 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_190446759 0.14 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_190541153 0.13 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr5_-_147286065 0.13 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr1_+_107683644 0.13 ENST00000370067.1
NTNG1
netrin G1
chr4_+_71457970 0.13 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr15_+_75080883 0.13 ENST00000567571.1
CSK
c-src tyrosine kinase
chr8_+_38831683 0.13 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr10_+_24497704 0.13 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr17_+_39240459 0.13 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr2_+_90248739 0.12 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr1_+_107682629 0.12 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr17_-_39280419 0.12 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr18_+_34124507 0.12 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr8_+_76452097 0.12 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr13_+_77522632 0.12 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr21_-_31538971 0.12 ENST00000286808.3
CLDN17
claudin 17
chr4_-_116034979 0.12 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr6_+_26365443 0.12 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr2_+_187454749 0.11 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr11_-_30608413 0.11 ENST00000528686.1
MPPED2
metallophosphoesterase domain containing 2
chr5_-_145562147 0.11 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr8_+_92261516 0.11 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr17_-_77924627 0.11 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr20_+_52105495 0.11 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_+_105050794 0.11 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr2_+_223162866 0.11 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr12_+_26348429 0.11 ENST00000242729.2
SSPN
sarcospan
chr7_+_50348268 0.11 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr8_-_40755333 0.11 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr12_-_3862245 0.10 ENST00000252322.1
ENST00000440314.2
EFCAB4B
EF-hand calcium binding domain 4B
chr7_+_148287657 0.10 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr6_-_100912785 0.10 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr4_+_88754069 0.10 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr7_-_23510086 0.10 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_214016314 0.10 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_-_138453559 0.10 ENST00000511115.1
PCDH18
protocadherin 18
chr1_-_39347255 0.10 ENST00000454994.2
ENST00000357771.3
GJA9
gap junction protein, alpha 9, 59kDa
chr12_+_93096759 0.10 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr16_+_57279004 0.10 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr5_-_36301984 0.09 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr1_-_152386732 0.09 ENST00000271835.3
CRNN
cornulin
chr5_+_67586465 0.09 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_88754113 0.09 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr3_-_167191814 0.09 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_+_122688090 0.09 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr5_-_126409159 0.09 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr2_+_179318295 0.09 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr1_-_149900122 0.09 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr18_+_32556892 0.08 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_+_98741041 0.08 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr7_-_25268104 0.08 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr8_+_22424551 0.08 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr18_+_61575200 0.08 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_-_100712292 0.08 ENST00000495063.1
ENST00000530539.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_-_28220354 0.08 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr7_-_83278322 0.08 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_+_151042224 0.08 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr9_+_82187630 0.08 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_+_69857515 0.08 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr6_+_12007897 0.08 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr9_+_82187487 0.08 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_+_99129513 0.08 ENST00000522319.1
ENST00000401707.2
POP1
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chrX_+_78003204 0.08 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr5_+_126984710 0.08 ENST00000379445.3
CTXN3
cortexin 3
chr4_-_87028478 0.07 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr17_-_40337470 0.07 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr5_+_140855495 0.07 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr3_-_12587055 0.07 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr2_-_207024233 0.07 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr3_+_111718173 0.07 ENST00000494932.1
TAGLN3
transgelin 3
chr2_-_207024134 0.07 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr19_+_10397648 0.07 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr18_-_3219847 0.07 ENST00000261606.7
MYOM1
myomesin 1
chr4_-_20985632 0.07 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr2_-_227050079 0.07 ENST00000423838.1
AC068138.1
AC068138.1
chr9_-_131486367 0.07 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr22_+_39101728 0.07 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr12_-_91573132 0.06 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr3_-_52090461 0.06 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr22_-_40929812 0.06 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_-_57272366 0.06 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr4_+_37962018 0.06 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr15_-_31393910 0.06 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr3_+_141106643 0.06 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chrX_+_139791917 0.06 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr3_-_138048682 0.06 ENST00000383180.2
NME9
NME/NM23 family member 9
chr14_-_38064198 0.06 ENST00000250448.2
FOXA1
forkhead box A1
chr1_-_67266939 0.06 ENST00000304526.2
INSL5
insulin-like 5
chr15_-_75748115 0.06 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr2_+_45168875 0.06 ENST00000260653.3
SIX3
SIX homeobox 3
chr2_-_207023918 0.06 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_+_154229547 0.06 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr9_+_82186872 0.06 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_16759711 0.06 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_10421853 0.06 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr8_-_18744528 0.06 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr6_+_135502501 0.06 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_185597619 0.05 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr5_-_1882858 0.05 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr3_-_54962100 0.05 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr3_+_121774202 0.05 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr14_+_73706308 0.05 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr2_+_68961905 0.05 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr12_-_110937351 0.05 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr2_-_224467093 0.05 ENST00000305409.2
SCG2
secretogranin II
chr4_-_57547454 0.05 ENST00000556376.2
HOPX
HOP homeobox
chr2_-_180610767 0.05 ENST00000409343.1
ZNF385B
zinc finger protein 385B

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2 0.6 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 1.3 GO:1901509 positive regulation of cAMP-mediated signaling(GO:0043950) regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0061346 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:1902159 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.6 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0045404 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.4 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters