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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MAF_NRL

Z-value: 1.23

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Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
MAF
ENSG00000178573.6 MAF bZIP transcription factor
NRL
ENSG00000129535.8 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFhg19_v2_chr16_-_79634595_79634620-0.776.8e-06Click!
NRLhg19_v2_chr14_-_24584138_24584223,
hg19_v2_chr14_-_24553834_24553850		0.154.6e-01Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_61869748 6.83 ENST00000357977.5
NFIA
nuclear factor I/A
chr6_+_132455118 5.05 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr4_+_42399856 4.26 ENST00000319234.4
SHISA3
shisa family member 3
chrX_-_63005405 4.18 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_100111479 3.96 ENST00000263174.4
PALMD
palmdelphin
chr1_+_100111580 3.28 ENST00000605497.1
PALMD
palmdelphin
chr1_-_208084729 3.10 ENST00000310833.7
ENST00000356522.4
CD34
CD34 molecule
chr2_+_12857043 3.04 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr2_-_191878681 2.78 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_64211112 2.65 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr19_+_39897453 2.62 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36
ZFP36 ring finger protein
chr3_+_193853927 2.34 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr2_-_191878162 2.27 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr4_+_41540160 2.25 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr15_-_70994612 2.11 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_-_70626314 2.06 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr9_-_13175823 1.99 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr22_+_27017921 1.90 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr10_+_94590910 1.88 ENST00000371547.4
EXOC6
exocyst complex component 6
chr1_+_61330931 1.87 ENST00000371191.1
NFIA
nuclear factor I/A
chr4_+_154125565 1.82 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr11_-_2160180 1.76 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_-_30107491 1.70 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr20_+_33759854 1.67 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr20_+_45338126 1.67 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr9_-_75567962 1.58 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr3_+_37903432 1.55 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr15_-_75248954 1.55 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr11_-_124632179 1.54 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr12_-_12491608 1.52 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr18_-_53253323 1.51 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr6_+_132455526 1.47 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr2_+_189156586 1.43 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr12_-_56615693 1.42 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41
ring finger protein 41
chr2_+_189156721 1.42 ENST00000409927.1
ENST00000409805.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr4_+_134070439 1.42 ENST00000264360.5
PCDH10
protocadherin 10
chr21_-_40033618 1.39 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr4_+_140586922 1.35 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr18_-_53253112 1.33 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr5_-_172198190 1.32 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr12_-_58220078 1.32 ENST00000549039.1
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr18_-_52969844 1.32 ENST00000561831.3
TCF4
transcription factor 4
chr11_+_71238313 1.29 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr2_-_191878874 1.29 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr4_+_186125391 1.29 ENST00000504273.1
SNX25
sorting nexin 25
chr12_-_42877764 1.28 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr1_-_109935819 1.26 ENST00000538502.1
SORT1
sortilin 1
chr9_-_35749162 1.25 ENST00000378094.4
ENST00000378103.3
GBA2
glucosidase, beta (bile acid) 2
chr2_-_136873735 1.20 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr4_-_99578776 1.19 ENST00000515287.1
TSPAN5
tetraspanin 5
chr3_+_38017264 1.19 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr2_+_189156389 1.19 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr5_-_111312622 1.17 ENST00000395634.3
NREP
neuronal regeneration related protein
chr19_+_39759154 1.17 ENST00000331982.5
IFNL2
interferon, lambda 2
chrX_-_62974941 1.16 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_7848364 1.15 ENST00000329913.3
GDF3
growth differentiation factor 3
chr15_-_52587945 1.15 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr1_+_33005020 1.10 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr6_+_37321748 1.07 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr2_-_188419200 1.07 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr20_+_34802295 1.07 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_-_2924720 1.06 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr5_+_179125368 1.05 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chr19_-_14628645 1.03 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_-_194991876 1.03 ENST00000310380.6
XXYLT1
xyloside xylosyltransferase 1
chr12_+_32260085 1.03 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr4_-_99578789 0.99 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr18_-_53089723 0.99 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chrX_+_13671225 0.98 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr6_-_41909191 0.98 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr1_+_78470530 0.97 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_-_111136513 0.97 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chrX_+_41306575 0.96 ENST00000342595.2
ENST00000378220.1
NYX
nyctalopin
chr12_+_51318513 0.96 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr3_+_32280159 0.96 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr15_-_82338460 0.95 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr4_-_138453606 0.95 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr2_-_220083076 0.95 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr17_+_61086917 0.95 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_+_50192499 0.94 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_-_111091948 0.93 ENST00000447165.2
NREP
neuronal regeneration related protein
chr11_-_2160611 0.93 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_129076151 0.93 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr11_-_118122996 0.91 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr14_+_23842018 0.91 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr16_-_31214051 0.89 ENST00000350605.4
PYCARD
PYD and CARD domain containing
chr2_+_219135115 0.89 ENST00000248451.3
ENST00000273077.4
PNKD
paroxysmal nonkinesigenic dyskinesia
chr6_+_37321823 0.89 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr14_+_57735614 0.88 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr7_-_94285472 0.88 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr9_-_98279241 0.87 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1
chr11_-_10829851 0.87 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr22_+_31277661 0.87 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
OSBP2
oxysterol binding protein 2
chr7_-_99679324 0.87 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr2_-_188419078 0.87 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_+_148737562 0.86 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr7_-_94285511 0.85 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr12_+_10366016 0.85 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_-_2924970 0.85 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr3_-_168864427 0.84 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr14_+_23067146 0.84 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr22_+_25465786 0.83 ENST00000401395.1
KIAA1671
KIAA1671
chr16_-_28550348 0.83 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr7_-_94285402 0.83 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr2_-_220435963 0.80 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr2_+_159313452 0.80 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr1_-_211752073 0.80 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr17_-_27503770 0.79 ENST00000533112.1
MYO18A
myosin XVIIIA
chr16_-_28550320 0.79 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr14_-_24977457 0.78 ENST00000250378.3
ENST00000206446.4
CMA1
chymase 1, mast cell
chr1_+_28764653 0.78 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr3_+_124303472 0.78 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr9_+_139557360 0.78 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7
EGF-like-domain, multiple 7
chr5_-_107717782 0.78 ENST00000542267.1
FBXL17
F-box and leucine-rich repeat protein 17
chr5_+_175298573 0.77 ENST00000512824.1
CPLX2
complexin 2
chr1_+_24645865 0.77 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr17_+_79373540 0.77 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr8_+_11666649 0.75 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chrX_-_24045303 0.75 ENST00000328046.8
KLHL15
kelch-like family member 15
chr5_+_167956121 0.75 ENST00000338333.4
FBLL1
fibrillarin-like 1
chr3_+_196366616 0.75 ENST00000426755.1
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr11_-_1780261 0.74 ENST00000427721.1
RP11-295K3.1
RP11-295K3.1
chr11_+_101785727 0.74 ENST00000263468.8
KIAA1377
KIAA1377
chr15_+_96875657 0.73 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_62704005 0.72 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr8_-_89339705 0.71 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr20_-_18774614 0.70 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr7_-_150754935 0.70 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr3_+_158991025 0.69 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr15_+_67813406 0.69 ENST00000342683.4
C15orf61
chromosome 15 open reading frame 61
chr16_-_24942655 0.68 ENST00000573765.1
ARHGAP17
Rho GTPase activating protein 17
chrY_-_6742068 0.68 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr4_-_123844084 0.68 ENST00000339154.2
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chrX_-_45060135 0.68 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr13_-_29069232 0.67 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr11_+_101983176 0.67 ENST00000524575.1
YAP1
Yes-associated protein 1
chr2_-_89385283 0.67 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr2_+_87754989 0.67 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chrX_+_84499081 0.66 ENST00000276123.3
ZNF711
zinc finger protein 711
chr20_+_4666882 0.66 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr12_-_46121554 0.66 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr2_+_87754887 0.66 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr15_-_59665062 0.66 ENST00000288235.4
MYO1E
myosin IE
chr2_+_87755054 0.66 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr1_+_24646002 0.65 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr12_+_19358228 0.65 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr3_+_50192537 0.64 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr6_+_32936353 0.64 ENST00000374825.4
BRD2
bromodomain containing 2
chr4_-_123843597 0.64 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr7_-_128415844 0.64 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr3_-_169587621 0.64 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr17_-_62084241 0.64 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr16_+_30960375 0.63 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr12_-_107380910 0.63 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr17_+_48172639 0.63 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr12_+_109785708 0.62 ENST00000310903.5
MYO1H
myosin IH
chrX_+_84498989 0.62 ENST00000395402.1
ZNF711
zinc finger protein 711
chr10_-_50396407 0.61 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr20_+_1246908 0.61 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr2_-_166651191 0.61 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr20_-_17511962 0.61 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr12_+_96588279 0.61 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr19_-_39735646 0.60 ENST00000413851.2
IFNL3
interferon, lambda 3
chr2_+_235887329 0.60 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3BP4
SH3-domain binding protein 4
chrX_+_84499038 0.60 ENST00000373165.3
ZNF711
zinc finger protein 711
chr4_-_76823681 0.59 ENST00000286719.7
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr9_+_35749203 0.59 ENST00000456972.2
ENST00000378078.4
RGP1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr17_-_76128488 0.59 ENST00000322914.3
TMC6
transmembrane channel-like 6
chr22_+_31518938 0.59 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr10_-_11653753 0.58 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr16_-_24942273 0.58 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr1_+_66999268 0.57 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_+_82186682 0.56 ENST00000376552.2
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_+_117063295 0.55 ENST00000525478.1
ENST00000532062.1
SIDT2
SID1 transmembrane family, member 2
chr22_+_36649170 0.55 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr5_+_175298674 0.55 ENST00000514150.1
CPLX2
complexin 2
chr17_+_18625336 0.54 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L
tripartite motif containing 16-like
chr19_-_58864848 0.54 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr3_+_38323785 0.54 ENST00000466887.1
ENST00000448498.1
SLC22A14
solute carrier family 22, member 14
chr3_+_152552685 0.54 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr1_-_25573977 0.54 ENST00000243189.7
C1orf63
chromosome 1 open reading frame 63
chr15_+_62359175 0.53 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chrX_+_51928002 0.53 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr17_-_39769005 0.53 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr1_+_2004901 0.53 ENST00000400921.2
PRKCZ
protein kinase C, zeta
chrX_+_123480421 0.52 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr5_+_78532003 0.52 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr3_-_98241358 0.52 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr16_-_15180257 0.51 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_-_25573937 0.51 ENST00000417642.2
ENST00000431849.2
C1orf63
chromosome 1 open reading frame 63
chr1_+_24645807 0.51 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr2_+_33701286 0.51 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_128400788 0.50 ENST00000409286.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr20_-_45985464 0.50 ENST00000458360.2
ENST00000262975.4
ZMYND8
zinc finger, MYND-type containing 8
chr7_+_95401851 0.50 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr16_+_610407 0.49 ENST00000409413.3
C16orf11
chromosome 16 open reading frame 11
chr15_+_67814008 0.49 ENST00000557807.1
C15orf61
chromosome 15 open reading frame 61
chr14_-_88459503 0.49 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr22_+_45148432 0.49 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8
Rho GTPase activating protein 8
chr7_-_8302298 0.48 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.9 2.6 GO:1904582 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.8 2.3 GO:0045608 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.8 3.1 GO:1900166 glial cell-derived neurotrophic factor secretion(GO:0044467) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.6 3.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 1.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 1.0 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.3 9.1 GO:0072189 ureter development(GO:0072189)
0.3 1.3 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.3 0.9 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 2.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 0.9 GO:0002588 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 0.9 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 0.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.3 1.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.3 0.8 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 0.8 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 0.8 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 0.8 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 2.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 1.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 1.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.9 GO:0010157 response to chlorate(GO:0010157)
0.2 1.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.6 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 1.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 1.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 0.5 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.8 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.6 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.8 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.9 GO:0009624 response to nematode(GO:0009624)
0.1 0.3 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.8 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.8 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.5 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 1.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:0060913 convergent extension involved in organogenesis(GO:0060029) cardiac cell fate determination(GO:0060913)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.4 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 2.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.7 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 1.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 1.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.9 GO:0015886 heme transport(GO:0015886)
0.1 0.7 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.5 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.5 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 0.3 GO:0042223 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.1 0.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.5 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 2.0 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 3.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.4 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.8 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.6 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 1.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.9 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 1.1 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 2.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.6 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 4.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 2.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 1.0 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 3.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 5.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 4.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.6 GO:0043090 amino acid import(GO:0043090)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.5 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.0 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.4 GO:0060324 face development(GO:0060324)
0.0 0.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.3 2.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 2.6 GO:0070578 RISC-loading complex(GO:0070578)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 2.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.0 GO:0043203 axon hillock(GO:0043203)
0.1 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.8 GO:0046930 pore complex(GO:0046930)
0.1 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 4.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 6.8 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 6.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 5.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 0.9 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 0.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.3 3.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 0.9 GO:0032090 Pyrin domain binding(GO:0032090)
0.3 0.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 3.1 GO:0043199 sulfate binding(GO:0043199)
0.3 1.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.3 1.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 0.8 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.8 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 1.1 GO:1903135 cupric ion binding(GO:1903135)
0.2 0.5 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2 1.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2 1.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 2.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.8 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 6.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 2.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 0.9 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0004096 catalase activity(GO:0004096)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 1.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 5.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0070402 NADPH binding(GO:0070402)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979) NAD+ binding(GO:0070403)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 12.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.9 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386) protein phosphatase 2B binding(GO:0030346)
0.0 0.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.0 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 6.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 8.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID ATM PATHWAY ATM pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 6.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 2.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions