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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for MAX_TFEB

Z-value: 0.55

Motif logo

Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
ENSG00000125952.14 MYC associated factor X
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41701581_417016130.242.5e-01Click!
MAXhg19_v2_chr14_-_65569186_655692430.213.0e-01Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57023406 1.57 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLR family, CARD domain containing 5
chr10_-_14050522 1.31 ENST00000342409.2
FERM domain containing 4A
chr1_-_212873267 1.29 ENST00000243440.1
basic leucine zipper transcription factor, ATF-like 3
chr3_-_127541679 1.19 ENST00000265052.5
monoglyceride lipase
chr15_+_89182178 1.14 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 1.14 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr21_+_42792442 1.13 ENST00000398600.2
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr12_-_123849374 1.13 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr19_+_45504688 1.12 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr19_+_49458107 1.11 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr19_+_10764937 1.09 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr1_+_154193325 1.04 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr14_+_93799556 1.03 ENST00000256339.4
unc-79 homolog (C. elegans)
chr15_+_89181974 1.02 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr10_-_49860525 0.95 ENST00000435790.2
Rho GTPase activating protein 22
chr20_-_44519839 0.94 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr12_+_113354341 0.90 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr16_+_5083950 0.90 ENST00000588623.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr2_-_133427767 0.86 ENST00000397463.2
LY6/PLAUR domain containing 1
chr1_+_11866270 0.84 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr19_+_10765003 0.81 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr19_+_10812108 0.76 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr1_-_154600421 0.75 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr11_+_69455855 0.74 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr19_-_47734448 0.73 ENST00000439096.2
BCL2 binding component 3
chr2_-_10587897 0.72 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr4_+_89299885 0.72 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr6_+_7107830 0.71 ENST00000379933.3
ras responsive element binding protein 1
chr14_+_24630465 0.71 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
interferon regulatory factor 9
chr4_+_89299994 0.70 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr6_+_7108210 0.70 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr19_-_10764509 0.69 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr6_+_87865262 0.69 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr12_-_58146128 0.68 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr1_-_241520385 0.67 ENST00000366564.1
regulator of G-protein signaling 7
chr9_+_74526384 0.66 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr1_+_92414952 0.64 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr13_+_113951532 0.64 ENST00000332556.4
lysosomal-associated membrane protein 1
chr12_-_122751002 0.63 ENST00000267199.4
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr1_-_241520525 0.62 ENST00000366565.1
regulator of G-protein signaling 7
chr14_+_77564440 0.62 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
CLOCK-interacting pacemaker
chr21_-_36421535 0.61 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr19_+_1067271 0.61 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr1_-_111743285 0.60 ENST00000357640.4
DENN/MADD domain containing 2D
chr7_+_100464760 0.59 ENST00000200457.4
thyroid hormone receptor interactor 6
chr12_-_49463753 0.59 ENST00000301068.6
Ras homolog enriched in brain like 1
chr21_-_36421626 0.59 ENST00000300305.3
runt-related transcription factor 1
chr5_-_121413974 0.59 ENST00000231004.4
lysyl oxidase
chr12_-_122750957 0.57 ENST00000451053.2
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr11_+_1718425 0.57 ENST00000382160.1
keratin associated protein 5-6
chr17_-_7137582 0.57 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr19_+_1067144 0.56 ENST00000313093.2
histocompatibility (minor) HA-1
chr19_-_5720123 0.56 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
lon peptidase 1, mitochondrial
chr19_-_5720248 0.55 ENST00000360614.3
lon peptidase 1, mitochondrial
chr12_-_58146048 0.55 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr10_-_31320840 0.55 ENST00000375311.1
zinc finger protein 438
chr4_-_47465666 0.55 ENST00000381571.4
COMM domain containing 8
chr19_+_14544099 0.55 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr5_+_176730769 0.55 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr5_+_34656569 0.54 ENST00000428746.2
retinoic acid induced 14
chr1_+_26737253 0.54 ENST00000326279.6
lin-28 homolog A (C. elegans)
chr19_-_5719860 0.54 ENST00000590729.1
lon peptidase 1, mitochondrial
chr5_+_34656331 0.53 ENST00000265109.3
retinoic acid induced 14
chr6_+_32811885 0.53 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_73851285 0.51 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr21_+_26934165 0.51 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr12_+_101673872 0.51 ENST00000261637.4
UTP20, small subunit (SSU) processome component, homolog (yeast)
chrX_+_30671476 0.51 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr7_-_2354099 0.50 ENST00000222990.3
sorting nexin 8
chr5_+_133706865 0.50 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr19_+_1067492 0.49 ENST00000586866.1
histocompatibility (minor) HA-1
chrX_+_128913906 0.48 ENST00000356892.3
SAM and SH3 domain containing 3
chr1_+_26737292 0.48 ENST00000254231.4
lin-28 homolog A (C. elegans)
chr8_+_104383728 0.48 ENST00000330295.5
collagen triple helix repeat containing 1
chr1_-_33116128 0.47 ENST00000436661.1
ENST00000373501.2
ENST00000341885.5
ENST00000468695.1
zinc finger and BTB domain containing 8 opposite strand
chr20_+_48552908 0.47 ENST00000244061.2
ring finger protein 114
chr10_-_25305011 0.47 ENST00000331161.4
ENST00000376363.1
enkurin, TRPC channel interacting protein
chr15_-_82555000 0.47 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr12_-_121342170 0.46 ENST00000353487.2
signal peptide peptidase like 3
chr10_+_51827648 0.46 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr1_+_40627038 0.45 ENST00000372771.4
rearranged L-myc fusion
chr10_-_99258135 0.45 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr6_+_7107999 0.44 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr7_-_41742697 0.44 ENST00000242208.4
inhibin, beta A
chr19_+_7587491 0.43 ENST00000264079.6
mucolipin 1
chr5_-_176730676 0.43 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr1_+_11796177 0.42 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
angiotensin II receptor-associated protein
chr16_+_57220193 0.42 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
ring finger and SPRY domain containing 1
chr1_-_100643765 0.42 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr2_+_216176540 0.42 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_-_27135591 0.42 ENST00000343060.4
ENST00000355633.5
homeobox A1
chr12_+_66217911 0.41 ENST00000403681.2
high mobility group AT-hook 2
chrX_+_95939638 0.41 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr5_+_148786518 0.41 ENST00000518014.1
ENST00000505340.1
ENST00000509909.1
AC131025.8
MIR143 host gene (non-protein coding)
chr12_+_64845660 0.41 ENST00000331710.5
TANK-binding kinase 1
chr12_+_56109926 0.41 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr9_-_34048873 0.41 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
ubiquitin associated protein 2
chr7_+_100271446 0.40 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr10_+_70883908 0.40 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
vacuolar protein sorting 26 homolog A (S. pombe)
chr1_+_11796126 0.40 ENST00000376637.3
angiotensin II receptor-associated protein
chr2_+_85981008 0.40 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr14_-_68283291 0.40 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr3_-_49967292 0.39 ENST00000455683.2
MON1 secretory trafficking family member A
chr7_+_916183 0.39 ENST00000265857.3
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr16_-_1401799 0.39 ENST00000007390.2
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr11_-_85780086 0.39 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr15_+_89164520 0.39 ENST00000332810.3
apoptosis enhancing nuclease
chr16_+_5121814 0.39 ENST00000262374.5
ENST00000586840.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr12_+_56109810 0.39 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr9_-_139137648 0.38 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr8_+_104426942 0.38 ENST00000297579.5
DDB1 and CUL4 associated factor 13
chr15_+_41913690 0.38 ENST00000563576.1
MGA, MAX dimerization protein
chr2_+_232063260 0.38 ENST00000349938.4
armadillo repeat containing 9
chr4_-_177713788 0.38 ENST00000280193.2
vascular endothelial growth factor C
chr7_+_100271355 0.37 ENST00000436220.1
ENST00000424361.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr18_+_9708162 0.37 ENST00000578921.1
RAB31, member RAS oncogene family
chr1_-_231376836 0.37 ENST00000451322.1
chromosome 1 open reading frame 131
chr1_-_111746966 0.37 ENST00000369752.5
DENN/MADD domain containing 2D
chr12_+_28343365 0.37 ENST00000545336.1
coiled-coil domain containing 91
chr11_-_615570 0.36 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr20_+_61287711 0.36 ENST00000370507.1
solute carrier organic anion transporter family, member 4A1
chr12_+_6833237 0.36 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COP9 signalosome subunit 7A
chr17_+_77030267 0.36 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr12_+_20848282 0.36 ENST00000545604.1
solute carrier organic anion transporter family, member 1C1
chr7_+_150759634 0.36 ENST00000392826.2
ENST00000461735.1
solute carrier family 4 (anion exchanger), member 2
chr6_-_134861089 0.36 ENST00000606039.1
RP11-557H15.4
chr20_-_44540686 0.36 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
phospholipid transfer protein
chr17_+_6915730 0.36 ENST00000548577.1
ribonuclease, RNase K
chr1_-_222885770 0.36 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr14_-_81687197 0.35 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr12_+_20848377 0.35 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
solute carrier organic anion transporter family, member 1C1
chrX_-_107979616 0.35 ENST00000372129.2
insulin receptor substrate 4
chr2_+_216176761 0.35 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_-_120980939 0.34 ENST00000426077.2
transmembrane protein 185B
chr10_+_60028818 0.34 ENST00000333926.5
CDGSH iron sulfur domain 1
chr1_-_155232221 0.34 ENST00000355379.3
secretory carrier membrane protein 3
chr12_+_7023735 0.34 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr17_-_41623716 0.34 ENST00000319349.5
ets variant 4
chr19_-_6424783 0.33 ENST00000398148.3
KH-type splicing regulatory protein
chrX_+_95939711 0.33 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr17_+_6915798 0.33 ENST00000402093.1
ribonuclease, RNase K
chr20_+_43595115 0.33 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
serine/threonine kinase 4
chr1_-_155232047 0.33 ENST00000302631.3
secretory carrier membrane protein 3
chr7_+_4815238 0.33 ENST00000348624.4
ENST00000401897.1
adaptor-related protein complex 5, zeta 1 subunit
chr2_-_176866978 0.33 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr19_-_36545649 0.33 ENST00000292894.1
THAP domain containing 8
chr17_-_36904437 0.32 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
polycomb group ring finger 2
chr1_+_11333245 0.32 ENST00000376810.5
UbiA prenyltransferase domain containing 1
chr2_-_10588630 0.32 ENST00000234111.4
ornithine decarboxylase 1
chr6_-_43197189 0.32 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr5_-_133706695 0.32 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr19_+_1275917 0.32 ENST00000469144.1
chromosome 19 open reading frame 24
chrX_+_131157322 0.32 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr11_-_72463421 0.32 ENST00000393609.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_+_110074685 0.32 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr6_-_43496605 0.31 ENST00000455285.2
exportin 5
chr17_+_40440481 0.31 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr12_-_114404111 0.31 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RNA binding motif protein 19
chrX_+_131157290 0.31 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr7_+_75024903 0.31 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr19_-_47290535 0.31 ENST00000412532.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr9_+_6757634 0.31 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr6_+_139349817 0.31 ENST00000367660.3
ABRA C-terminal like
chr18_-_3247084 0.31 ENST00000609924.1
RP13-270P17.3
chr20_+_2821340 0.31 ENST00000380445.3
ENST00000380469.3
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr1_-_52831796 0.31 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
coiled-coil and C2 domain containing 1B
chr12_+_7023491 0.31 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chrX_+_100663243 0.30 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_-_43337180 0.30 ENST00000318149.3
ENST00000361428.2
zinc finger protein 318
chr16_+_2098003 0.30 ENST00000439673.2
ENST00000350773.4
tuberous sclerosis 2
chr16_+_84178874 0.30 ENST00000378553.5
dynein, axonemal, assembly factor 1
chr12_-_125473600 0.30 ENST00000308736.2
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr11_-_615942 0.30 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr19_+_40854559 0.30 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr3_-_49761337 0.30 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chrX_+_146993449 0.30 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr2_-_148778258 0.30 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr2_-_148778323 0.30 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr15_-_83316254 0.29 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr14_-_65569186 0.29 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MYC associated factor X
chr16_+_2570340 0.29 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr1_-_205290865 0.29 ENST00000367157.3
NUAK family, SNF1-like kinase, 2
chr16_-_4466622 0.29 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr11_+_64781657 0.29 ENST00000533729.1
ADP-ribosylation factor-like 2
chr17_-_39216344 0.29 ENST00000391418.2
keratin associated protein 2-3
chr19_+_45681997 0.28 ENST00000433642.2
biogenesis of lysosomal organelles complex-1, subunit 3
chr16_-_5083917 0.28 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_+_156712372 0.28 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr16_-_4466565 0.28 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16 readthrough
coronin 7
chr12_+_54332535 0.28 ENST00000243056.3
homeobox C13
chr12_-_76953573 0.28 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr15_-_40213080 0.28 ENST00000561100.1
G protein-coupled receptor 176
chr10_+_46222648 0.28 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
family with sequence similarity 21, member C
chr19_-_12833164 0.28 ENST00000356861.5
transportin 2
chr6_-_32811771 0.28 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr2_-_47572105 0.28 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr10_+_70480963 0.27 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
cell division cycle and apoptosis regulator 1
chr12_+_53662110 0.27 ENST00000552462.1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr19_-_40854417 0.27 ENST00000582006.1
ENST00000582783.1
chromosome 19 open reading frame 47
chr1_+_171454639 0.27 ENST00000392078.3
ENST00000426496.2
proline-rich coiled-coil 2C

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 1.7 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.5 1.9 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 1.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 1.8 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 1.6 GO:0060339 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 1.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 0.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.2 0.7 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.9 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 1.2 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.8 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 1.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 1.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.5 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.5 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.4 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.7 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 1.1 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 1.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.4 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:1901355 response to rapamycin(GO:1901355)
0.1 2.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.3 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.4 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.3 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.5 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.2 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0032764 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.1 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 2.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:1902024 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0034163 negative regulation of interferon-alpha production(GO:0032687) regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 1.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.7 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1901859 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:1901098 maintenance of Golgi location(GO:0051684) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.3 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:1902902 posttranslational protein targeting to membrane(GO:0006620) negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:1904415 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0 0.1 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.4 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.0 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.5 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:0051798 positive regulation of hair follicle development(GO:0051798) death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 1.2 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.5 GO:0019034 viral replication complex(GO:0019034)
0.2 1.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.6 GO:0030897 HOPS complex(GO:0030897)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 2.9 GO:0015030 Cajal body(GO:0015030)
0.0 2.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.7 GO:0030684 preribosome(GO:0030684)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 2.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:1903349 extrinsic component of omegasome membrane(GO:0097629) omegasome membrane(GO:1903349)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 1.7 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.7 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.2 0.5 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.2 0.5 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.4 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.4 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 3.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 2.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.0 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL