Project

Inflammatory response time course, HUVEC (Wada et al., 2009)

Navigation
Downloads

Results for MBD2

Z-value: 0.85

Motif logo

logo of

Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51751132_517511580.222.9e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_39317868 4.08 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr17_+_65821636 3.63 ENST00000544778.2
BPTF
bromodomain PHD finger transcription factor
chr17_+_65821780 2.73 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr8_+_37654693 2.18 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr11_+_74459876 2.12 ENST00000299563.4
RNF169
ring finger protein 169
chr5_+_153570285 1.96 ENST00000425427.2
ENST00000297107.6
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr8_-_93115445 1.96 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_37654424 1.83 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr17_-_62915574 1.82 ENST00000339474.5
ENST00000581368.1
LRRC37A3
leucine rich repeat containing 37, member A3
chr1_+_82266053 1.72 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr19_-_14201507 1.68 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr17_+_68165657 1.49 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_-_124774802 1.45 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr2_+_42275153 1.45 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr12_+_27396901 1.42 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr5_+_153570319 1.37 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr1_+_84543734 1.36 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_-_80915059 1.34 ENST00000377104.3
SPRY2
sprouty homolog 2 (Drosophila)
chr11_-_89224488 1.31 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr11_-_89224299 1.24 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NOX4
NADPH oxidase 4
chr12_+_122064673 1.18 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_+_25870070 1.17 ENST00000374338.4
LDLRAP1
low density lipoprotein receptor adaptor protein 1
chr6_+_37321748 1.11 ENST00000373479.4
ENST00000394443.4
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr2_+_9346892 1.06 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr13_+_27131798 1.04 ENST00000361042.4
WASF3
WAS protein family, member 3
chr17_-_61920280 1.02 ENST00000448276.2
ENST00000577990.1
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr11_-_89224508 1.01 ENST00000525196.1
NOX4
NADPH oxidase 4
chr6_+_1610681 1.01 ENST00000380874.2
FOXC1
forkhead box C1
chr13_+_27131887 1.00 ENST00000335327.5
WASF3
WAS protein family, member 3
chr19_-_11308190 0.98 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr7_-_21985656 0.98 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr11_-_89224139 0.97 ENST00000413594.2
NOX4
NADPH oxidase 4
chr1_+_6845578 0.96 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr11_-_2160180 0.95 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_107811162 0.95 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr15_-_65067773 0.94 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr18_+_77155942 0.94 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr12_-_57824739 0.94 ENST00000347140.3
ENST00000402412.1
R3HDM2
R3H domain containing 2
chr6_-_16761678 0.93 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr1_+_6845497 0.92 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr8_-_57123815 0.92 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr12_-_31744031 0.90 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr14_+_53019993 0.89 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr14_-_89883412 0.89 ENST00000557258.1
FOXN3
forkhead box N3
chr15_-_56035177 0.89 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr14_+_53019822 0.84 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr2_-_54014127 0.83 ENST00000394717.2
GPR75-ASB3
GPR75-ASB3 readthrough
chr12_+_19282713 0.82 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr2_+_47630255 0.81 ENST00000406134.1
MSH2
mutS homolog 2
chrX_-_62974941 0.81 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_-_89224638 0.79 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr19_-_11373128 0.79 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chr19_-_19051103 0.79 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr10_+_129845823 0.78 ENST00000306042.5
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_-_17356697 0.78 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr13_+_21277482 0.77 ENST00000304920.3
IL17D
interleukin 17D
chr17_+_19552036 0.76 ENST00000581518.1
ENST00000395575.2
ENST00000584332.2
ENST00000339618.4
ENST00000579855.1
ALDH3A2
aldehyde dehydrogenase 3 family, member A2
chr4_+_79697495 0.74 ENST00000502871.1
ENST00000335016.5
BMP2K
BMP2 inducible kinase
chr18_+_77155856 0.74 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr11_-_75236867 0.74 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr6_+_148663729 0.73 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr18_-_72921303 0.71 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr11_-_2160611 0.70 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_-_128206759 0.69 ENST00000430265.2
GATA2
GATA binding protein 2
chr4_-_78740511 0.69 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr1_+_215740709 0.69 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr16_+_3019552 0.68 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr5_-_180076613 0.67 ENST00000261937.6
ENST00000393347.3
FLT4
fms-related tyrosine kinase 4
chr16_+_3019246 0.66 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr19_+_35491174 0.64 ENST00000317991.5
ENST00000504615.2
GRAMD1A
GRAM domain containing 1A
chr9_-_130617029 0.64 ENST00000373203.4
ENG
endoglin
chr11_+_43380459 0.63 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr9_-_130616915 0.63 ENST00000344849.3
ENG
endoglin
chr5_-_39425290 0.62 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_+_86781847 0.61 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr7_+_73082152 0.61 ENST00000324941.4
ENST00000451519.1
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr19_+_10527449 0.61 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr18_-_34408802 0.61 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr5_+_122847908 0.59 ENST00000511130.2
ENST00000512718.3
CSNK1G3
casein kinase 1, gamma 3
chr2_-_54014055 0.59 ENST00000263634.3
ENST00000406687.1
GPR75-ASB3
GPR75-ASB3 readthrough
chr19_+_39904168 0.59 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_-_89787360 0.57 ENST00000389386.3
VPS9D1
VPS9 domain containing 1
chr16_-_49890016 0.55 ENST00000563137.2
ZNF423
zinc finger protein 423
chr19_-_14201776 0.55 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr3_+_170075436 0.55 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr12_+_19282643 0.54 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr19_+_35491330 0.53 ENST00000411896.2
ENST00000424536.2
GRAMD1A
GRAM domain containing 1A
chr18_+_56530794 0.53 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr7_+_86781677 0.53 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_-_107717058 0.53 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr22_+_19701985 0.53 ENST00000455784.2
ENST00000406395.1
SEPT5
septin 5
chr6_+_90142884 0.53 ENST00000369408.5
ENST00000339746.4
ENST00000447838.2
ANKRD6
ankyrin repeat domain 6
chr1_+_116184566 0.52 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chr11_+_67056755 0.51 ENST00000511455.2
ENST00000308440.6
ANKRD13D
ankyrin repeat domain 13 family, member D
chr19_-_42759300 0.51 ENST00000222329.4
ERF
Ets2 repressor factor
chr2_-_129076151 0.51 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr10_-_103880209 0.49 ENST00000425280.1
LDB1
LIM domain binding 1
chr2_+_11052054 0.49 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr11_+_67056867 0.48 ENST00000514166.1
ANKRD13D
ankyrin repeat domain 13 family, member D
chr14_-_74416829 0.48 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr15_-_82338460 0.48 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr10_+_35416223 0.48 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr12_-_31743901 0.48 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr11_+_67055986 0.48 ENST00000447274.2
ANKRD13D
ankyrin repeat domain 13 family, member D
chr3_+_33155444 0.48 ENST00000320954.6
CRTAP
cartilage associated protein
chr1_+_84543821 0.47 ENST00000370688.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_50222187 0.47 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr20_-_60640866 0.47 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr1_+_156698234 0.46 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr17_-_27278304 0.46 ENST00000577226.1
PHF12
PHD finger protein 12
chrX_+_9983602 0.45 ENST00000380861.4
WWC3
WWC family member 3
chr2_+_220306745 0.45 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr14_-_75593708 0.45 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr12_+_46123448 0.44 ENST00000334344.6
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr3_-_196295437 0.44 ENST00000429115.1
WDR53
WD repeat domain 53
chr20_-_46415341 0.44 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr20_-_46415297 0.43 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr19_+_56152262 0.43 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr14_+_93651296 0.42 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr14_+_93651358 0.42 ENST00000415050.2
TMEM251
transmembrane protein 251
chr16_-_4166186 0.42 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr19_-_36545649 0.41 ENST00000292894.1
THAP8
THAP domain containing 8
chr12_-_57400227 0.41 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr1_-_6545502 0.41 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_+_14989186 0.41 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr2_+_113033164 0.40 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr2_+_181845074 0.40 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr14_-_93581615 0.40 ENST00000555553.1
ENST00000555495.1
ENST00000554999.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr7_-_8301869 0.40 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr5_-_81046841 0.39 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr3_-_196295468 0.38 ENST00000332629.5
ENST00000433160.1
WDR53
WD repeat domain 53
chr18_-_812231 0.38 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_-_153919128 0.38 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr10_-_25012597 0.38 ENST00000396432.2
ARHGAP21
Rho GTPase activating protein 21
chr7_-_17980091 0.38 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr3_-_183735651 0.38 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_8301768 0.38 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr7_-_8301682 0.37 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr12_-_56583243 0.37 ENST00000550164.1
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr1_-_36022979 0.37 ENST00000469892.1
ENST00000325722.3
KIAA0319L
KIAA0319-like
chr18_-_53255766 0.36 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr18_+_33552667 0.36 ENST00000333234.5
C18orf21
chromosome 18 open reading frame 21
chr2_+_178257372 0.36 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr7_-_94285402 0.35 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr2_+_198669365 0.35 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr4_+_71570430 0.35 ENST00000417478.2
RUFY3
RUN and FYVE domain containing 3
chr4_+_174089904 0.35 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr18_-_812517 0.35 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr17_+_54671047 0.35 ENST00000332822.4
NOG
noggin
chr11_-_47198380 0.35 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr17_-_46690839 0.34 ENST00000498634.2
HOXB8
homeobox B8
chr2_+_181845843 0.34 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_+_52608046 0.34 ENST00000357206.2
ENST00000287727.3
ZFYVE9
zinc finger, FYVE domain containing 9
chr5_-_37249397 0.34 ENST00000425232.2
ENST00000274258.7
C5orf42
chromosome 5 open reading frame 42
chr14_+_102829300 0.33 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr4_-_16228083 0.33 ENST00000399920.3
TAPT1
transmembrane anterior posterior transformation 1
chr13_-_52027134 0.33 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chrX_-_134049233 0.33 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr2_+_219264466 0.33 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_-_10341948 0.33 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr22_-_20004330 0.33 ENST00000263207.3
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr7_-_94285472 0.33 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr2_+_181845298 0.33 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr13_-_21476900 0.33 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr7_-_94285511 0.33 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr1_+_3689325 0.33 ENST00000444870.2
ENST00000452264.1
SMIM1
small integral membrane protein 1 (Vel blood group)
chr2_+_219536749 0.32 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36
serine/threonine kinase 36
chr3_+_197518100 0.32 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_-_105307711 0.32 ENST00000519645.1
ENST00000262903.4
ENST00000369125.2
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr12_+_57482665 0.32 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr7_+_129710350 0.32 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr10_+_104404218 0.31 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr11_-_73309228 0.31 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr5_+_176237478 0.31 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr12_+_46123682 0.31 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr18_-_34408902 0.31 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr12_+_2986359 0.31 ENST00000538636.1
ENST00000461997.2
ENST00000489288.2
ENST00000366285.2
ENST00000538700.1
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr21_+_45875354 0.31 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr3_-_185542761 0.30 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_220408430 0.30 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr5_-_176900610 0.30 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
DBN1
drebrin 1
chr18_-_34408693 0.29 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr7_+_69064566 0.29 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr12_+_111051832 0.29 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr1_-_154531095 0.28 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_7037461 0.28 ENST00000396684.2
ATN1
atrophin 1
chr7_+_69064300 0.28 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr12_+_57482877 0.28 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr9_+_35605274 0.28 ENST00000336395.5
TESK1
testis-specific kinase 1
chr12_+_111051902 0.28 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr16_-_17564738 0.28 ENST00000261381.6
XYLT1
xylosyltransferase I
chr2_+_219537015 0.28 ENST00000440309.1
ENST00000424080.1
STK36
serine/threonine kinase 36
chr14_-_103523745 0.27 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr14_+_74417192 0.27 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr3_-_185542817 0.27 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr3_-_149688896 0.27 ENST00000239940.7
PFN2
profilin 2
chr2_-_100106419 0.27 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chrX_+_18443703 0.27 ENST00000379996.3
CDKL5
cyclin-dependent kinase-like 5
chr9_+_132597722 0.27 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
USP20
ubiquitin specific peptidase 20
chr12_+_107168418 0.27 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 1.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.3 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.0 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 1.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 1.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3 1.8 GO:0097338 response to clozapine(GO:0097338)
0.3 0.3 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.7 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 1.4 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 0.8 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.2 0.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 5.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 1.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 2.0 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 4.7 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.8 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.7 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.2 GO:0003163 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.1 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 2.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 3.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0002652 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 1.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0048711 positive regulation of isotype switching to IgE isotypes(GO:0048295) positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.7 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 1.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0035878 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 1.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.6 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.4 GO:0016589 NURF complex(GO:0016589)
0.4 1.3 GO:0072563 endothelial microparticle(GO:0072563)
0.3 5.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 0.8 GO:0032302 MutSbeta complex(GO:0032302)
0.2 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.4 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 3.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 0.8 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.3 0.8 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.3 GO:0005534 galactose binding(GO:0005534)
0.2 0.9 GO:0034046 poly(G) binding(GO:0034046)
0.1 3.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 1.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 6.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 7.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 3.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions